Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 76 (05 Jun 2019)
Sequence version 1 (25 Jul 2006)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

AAEL010606-PA

Gene

AAEL010606

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AAEL010606-PAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:AAEL010606Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7159 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008820 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1603 – 1624HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7159.AAEL010606-PA

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini17 – 110Ig-likeInterPro annotationAdd BLAST94
Domaini116 – 212Ig-likeInterPro annotationAdd BLAST97
Domaini229 – 320Ig-likeInterPro annotationAdd BLAST92
Domaini324 – 403Ig-likeInterPro annotationAdd BLAST80
Domaini410 – 504Ig-likeInterPro annotationAdd BLAST95
Domaini509 – 593Ig-likeInterPro annotationAdd BLAST85
Domaini600 – 694Ig-likeInterPro annotationAdd BLAST95
Domaini697 – 790Ig-likeInterPro annotationAdd BLAST94
Domaini795 – 887Ig-likeInterPro annotationAdd BLAST93
Domaini896 – 991Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini996 – 1098Fibronectin type-IIIInterPro annotationAdd BLAST103
Domaini1103 – 1199Fibronectin type-IIIInterPro annotationAdd BLAST97
Domaini1203 – 1294Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini1296 – 1378Ig-likeInterPro annotationAdd BLAST83
Domaini1386 – 1479Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini1483 – 1578Fibronectin type-IIIInterPro annotationAdd BLAST96

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1087 – 1106DisorderedSequence analysisAdd BLAST20
Regioni1790 – 1829DisorderedSequence analysisAdd BLAST40
Regioni1859 – 1990DisorderedSequence analysisAdd BLAST132

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1790 – 1819PolarSequence analysisAdd BLAST30
Compositional biasi1951 – 1968PolyampholyteSequence analysisAdd BLAST18

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IQJM Eukaryota
ENOG410XQX7 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000230554

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q16SD7

Identification of Orthologs from Complete Genome Data

More...
OMAi
PSIRAMK

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q16SD7

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 6 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 16 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR021012 Dscam_C
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12355 Dscam_C, 1 hit
PF00041 fn3, 6 hits
PF07679 I-set, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060 FN3, 6 hits
SM00409 IG, 9 hits
SM00408 IGc2, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 9 hits
SSF49265 SSF49265, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853 FN3, 6 hits
PS50835 IG_LIKE, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q16SD7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVESVEAASK VDDSKGPVFL KEPTNRIDFS NSTGAVVECS ATGNPPPEMI
60 70 80 90 100
WIRSDGTAVG EVPGLRQILP NGNLVFPPFR AEDYRQDVHA QVYACMAKNQ
110 120 130 140 150
FGSIISRDVN VRAVVQQYYE ADVNKEHVIR GNSAILKCLI PSFVADFVDV
160 170 180 190 200
VSWTDEENTY VYSSATAAED SDGKYMVLPS GELHIREVGP EDGYKSYQCR
210 220 230 240 250
TKHRLTGETR LSATKGRLVI TEPISSTPPK TPSLMQKPVE VNPSTDTALL
260 270 280 290 300
CLAQGFPAPN FRWYKYIEGT TRKQAVVLNE RVKQVSGTLI IKDAVVDDSG
310 320 330 340 350
KYLCVVNNSV GGESVETVLT VTAPLTAKIE PRTQTVDFGR PAVFTCKFSG
360 370 380 390 400
NPIKTVSWMK DGKALGHSDA VLRIESVKKE DKGMYQCFIR NDQESAQASA
410 420 430 440 450
ELKLGGRFDP PVIREAFPEE TRHPGPSVFL KCIAGGNPTP EISWELDGKK
460 470 480 490 500
ITNSDRYQVG QYVTVNGDVV SHLNITSLHS NDGGLYKCIA SSKVGVAEHS
510 520 530 540 550
AKLNVYGLPY VRTMEKKSIV AGETLIVTCP VAGYPIDSIV WERDNRQLPI
560 570 580 590 600
NRKQKVFPNG TLIIENVERN SDQATYTCVA KNSEGYTARG TLEVAVMVPP
610 620 630 640 650
SITPFSFGEE TLNSGESTAV QCMVYKGDAP LEIRWYFNGQ LLPSNENGVI
660 670 680 690 700
IARMTERLSS LSIDPISHYH RGVYECRAKN KAGESVQSSE LVINVPPRWI
710 720 730 740 750
LEPTDKAFAQ GSNAKVECKA DGFPKPQVSW KKAIGDTPGE YKDLRSNDSS
760 770 780 790 800
IRVEEGSLFI NNIQKSNEGY YLCEAINGIG SGLSAVILIS VQAPPEFTEK
810 820 830 840 850
LRNQTARRGE PTVLQCEAKG EKPIGILWNM NNIRLDPKSD NRYTIREEIR
860 870 880 890 900
PDGVMSSLSI KRTERSDSAL FTCMATNAFG SDDASINMII QEAPEMPYAL
910 920 930 940 950
KVLDKSGRTV QLSWAKPYDG NSPLKRYIIE FKRSRGTWEN DVDRVIVPGH
960 970 980 990 1000
TNEAQVQKLS PATTYNIRIV AENDIGVSDS SEVVTIITAE EAPSGKPQAI
1010 1020 1030 1040 1050
KVEPTNQSTL RVSWKAPPRA EWNGDILGYY VGFKQTSQNS SYIYETVNYS
1060 1070 1080 1090 1100
LEGGEGKEHS LEINNLKTYT QYSIVIQAFN KVGAGPMSEE EKQYTAEGTP
1110 1120 1130 1140 1150
DQPPSDTMCT TLTSQTIRVS WVSPPLESAN GVIKGYKVVY SPSELWNDDK
1160 1170 1180 1190 1200
NKDYKKTASS DTVLHGLKKY TNYTMQVLAT TSGGDGVRSA PIHCQTEQDV
1210 1220 1230 1240 1250
PEAPTAVKAL VMSEGSILVS WQPPSQPNGV ILQYTVYIKI GDQEPKSHKV
1260 1270 1280 1290 1300
PSYQMSYEAS GLEKNQQYDF WVTASTTIGE GQRSKMLSAM PSDKVPAKIA
1310 1320 1330 1340 1350
SFDDTFTATF KEDAKLPCLA VGSPTPDITW KIKGQEFVPN ERIRQLPEGS
1360 1370 1380 1390 1400
LFIKDVIRQD AGDYTCTAEN SIAKDSITHR LIVLAPPQSP QLTLTATTTD
1410 1420 1430 1440 1450
SLAVKLKPHE SDTAPLQGYT LHYKPEFGDW ETSDVALDAP KYTIENLYCG
1460 1470 1480 1490 1500
SRYQVYATAY NTIGAGEPSD ILNTRTKGSK PLLPEKSRFI EASSNSITLH
1510 1520 1530 1540 1550
LPAWKDGGCR MSHFVVENKK KDQPDWNQIS NNVKPGGNFV VLDLEPATWY
1560 1570 1580 1590 1600
NLRVTAHNNA GFTVAEYEFA TLTITGGTIA PTRDIPELTA EDTIRIILSN
1610 1620 1630 1640 1650
LNLVVPVVAA LLVIIIAIIV ICVLRNKGNN NKDDVVYNQS MGPAGAATLD
1660 1670 1680 1690 1700
KRRPDIRDEL GYIAPPNRKL PPVPGSNYNT CDRVKRGTVI SHNPINKSNH
1710 1720 1730 1740 1750
STWDPRRPLY EELKNVQAPA LPRRCNHPPA CYGMEDEICP YATFHLLGFR
1760 1770 1780 1790 1800
EEMDPTKAMN FQTFPHQNGM GGPGHMGTMG SNMAMQVPNH VHSRSGSQSM
1810 1820 1830 1840 1850
PRQNRYARKN SQGGQSSIYT PAPEYDDPAN CAEEDQYRRY TRINSQGGSL
1860 1870 1880 1890 1900
YCGPGPEYDD PANCAPEEDQ YGSQYGGNYG TPYDHYGSRG SVGRRSVGSP
1910 1920 1930 1940 1950
EPPPPPPRNH DTSNSSFNDS KESNEISEAE CDRDNGPRGN YGATAKTTDA
1960 1970 1980 1990
LNAEETEKLL KQRNEVKPKY AKQTAAPASA GLTAYDTMAV
Length:1,990
Mass (Da):219,098
Last modified:July 25, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i60A6540EC7D53B10
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CH477675 Genomic DNA Translation: EAT37388.1

NCBI Reference Sequences

More...
RefSeqi
XP_001660953.1, XM_001660903.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477675 Genomic DNA Translation: EAT37388.1
RefSeqiXP_001660953.1, XM_001660903.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7159.AAEL010606-PA

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IQJM Eukaryota
ENOG410XQX7 LUCA
HOGENOMiHOG000230554
InParanoidiQ16SD7
OMAiPSIRAMK
PhylomeDBiQ16SD7

Family and domain databases

CDDicd00063 FN3, 6 hits
Gene3Di2.60.40.10, 16 hits
InterProiView protein in InterPro
IPR021012 Dscam_C
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF12355 Dscam_C, 1 hit
PF00041 fn3, 6 hits
PF07679 I-set, 5 hits
SMARTiView protein in SMART
SM00060 FN3, 6 hits
SM00409 IG, 9 hits
SM00408 IGc2, 9 hits
SUPFAMiSSF48726 SSF48726, 9 hits
SSF49265 SSF49265, 3 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 6 hits
PS50835 IG_LIKE, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ16SD7_AEDAE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q16SD7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: June 5, 2019
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again