UniProtKB - Q16IB4 (DAN_AEDAE)
Protein
Protein distal antenna
Gene
dan
Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Functioni
Probable transcription factor with a role in the retinal determination (RD) network. Contributes to differentiation of antenna-specific characteristics (By similarity).By similarity
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 32 – 52 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 21 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity Source: UniProtKB
GO - Biological processi
- antennal development Source: UniProtKB
- compound eye development Source: UniProtKB
- regulation of transcription, DNA-templated Source: UniProtKB
- segment specification Source: UniProtKB
Keywordsi
Molecular function | Developmental protein, DNA-binding |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Protein distal antennaBy similarity |
Gene namesi | Name:danBy similarity ORF Names:AAEL013733 |
Organismi | Aedes aegypti (Yellowfever mosquito) (Culex aegypti) |
Taxonomic identifieri | 7159 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | VectorBase:AAEL013733 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotationBy similarity
Nucleus
- nucleus Source: UniProtKB
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000351198 | 1 – 675 | Protein distal antennaAdd BLAST | 675 |
Keywords - PTMi
PhosphoproteinProteomic databases
PRIDEi | Q16IB4 |
Interactioni
Subunit structurei
Homomers.
Interacts with itself, danr, ey and dac to form a complex (or complexes) containing the RD factors (By similarity).
By similarityProtein-protein interaction databases
STRINGi | 7159.AAEL013733-PA |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 56 | HTH psq-typePROSITE-ProRule annotationAdd BLAST | 52 |
Phylogenomic databases
eggNOGi | ENOG502S5K1, Eukaryota |
HOGENOMi | CLU_405596_0_0_1 |
InParanoidi | Q16IB4 |
OrthoDBi | 1534815at2759 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR007889, HTH_Psq IPR036388, WH-like_DNA-bd_sf |
Pfami | View protein in Pfam PF04218, CENP-B_N, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS50960, HTH_PSQ, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q16IB4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMMATKGKRP LRHLTATDKI DAIQRIHDGE SKASVARDIG VPESTLRGWC
60 70 80 90 100
KNEEKLRYMS RQSAENAEKL TNEATAAALT AVAAAELFNG PPEKRLKLEQ
110 120 130 140 150
GLFGNGKLKY DDSFYKSPRG PMNGLDLSGG DKGLGVSGGD IIMNGLHGAD
160 170 180 190 200
FSSKSKEMNL KGYGADLSKH GDPKQADLSM AAISPLTSLS HLSGMSGLAQ
210 220 230 240 250
SPLALSFNEI ATNLNLFAQL NNNHNLATMS NLGGLSAAQS LRNARPKANT
260 270 280 290 300
SQSPRTSNLS DVNGDKNPSL TVRNLAKLQQ KNSGDLSNGM MHGINLSDKY
310 320 330 340 350
KQQPSAAPLG RDTNAPVDEA LWYWLKSQQA MLGLNNLYSS MPRPSSPQQS
360 370 380 390 400
SSPPQQHQQV QHHPSTQTPT PPIVSTPQPT PPSSAPSLTP EDTKNSSWFW
410 420 430 440 450
QWYKTFGASL MPGDKSNNNT INANANSKQA AYENILYSQL TKGQNSDSLN
460 470 480 490 500
NNAQPINLNI ISSNGPENVK SEPEDLSNHN HSSSNAAAVA APAEDLQRFN
510 520 530 540 550
PSPSTSAKSE LKQEDDEEQA GPADDESPME SKCNGKVKDV LDNFLFQNPS
560 570 580 590 600
SNDRASPANL SIRSNNSPRR RSVSPAVSNH HVNSPEPENG DLAHKSDISE
610 620 630 640 650
DSNHMLVADI KSSAEAVEHG EKFLKWLEAC SDPNVTAMQV MQFKYLLNSI
660 670
KLSAERQQQN AVSSGEERTR VRRRK
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A6I8TFR3 | A0A6I8TFR3_AEDAE | Protein distal antenna | 5578527 | 677 | Annotation score: | ||
A0A6I8TQR0 | A0A6I8TQR0_AEDAE | Protein distal antenna | 5578527 | 698 | Annotation score: |
Sequence cautioni
The sequence EAT34003 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH478090 Genomic DNA Translation: EAT34003.1 Sequence problems. |
RefSeqi | XP_001663918.1, XM_001663868.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH478090 Genomic DNA Translation: EAT34003.1 Sequence problems. |
RefSeqi | XP_001663918.1, XM_001663868.1 |
3D structure databases
SMRi | Q16IB4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7159.AAEL013733-PA |
Proteomic databases
PRIDEi | Q16IB4 |
Organism-specific databases
VEuPathDBi | VectorBase:AAEL013733 |
Phylogenomic databases
eggNOGi | ENOG502S5K1, Eukaryota |
HOGENOMi | CLU_405596_0_0_1 |
InParanoidi | Q16IB4 |
OrthoDBi | 1534815at2759 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR007889, HTH_Psq IPR036388, WH-like_DNA-bd_sf |
Pfami | View protein in Pfam PF04218, CENP-B_N, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS50960, HTH_PSQ, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DAN_AEDAE | |
Accessioni | Q16IB4Primary (citable) accession number: Q16IB4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | February 10, 2021 | |
This is version 83 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |