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UniProtKB - Q16864 (VATF_HUMAN)

Entry version 167 (13 Nov 2019)
Sequence version 2 (20 Feb 2007)
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Protein

V-type proton ATPase subunit F

Gene

ATP6V1F

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processHydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		MetaCyc:HS05192-MONOMER

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-1222556 ROS and RNS production in phagocytes
R-HSA-77387 Insulin receptor recycling
R-HSA-917977 Transferrin endocytosis and recycling
R-HSA-9639288 Amino acids regulate mTORC1
R-HSA-983712 Ion channel transport

Protein family/group databases

Transport Classification Database

More...TCDBi		3.A.2.2.4 the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
V-type proton ATPase subunit F
Short name:
V-ATPase subunit F
Alternative name(s):
V-ATPase 14 kDa subunit
Vacuolar proton pump subunit F
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ATP6V1F
Synonyms:ATP6S14, VATF
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:16832 ATP6V1F

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		607160 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q16864

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		9296

Open Targets

More...OpenTargetsi		ENSG00000128524

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38421

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q16864

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ATP6V1F

Domain mapping of disease mutations (DMDM)

More...DMDMi		126302612

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001447991 – 119V-type proton ATPase subunit FAdd BLAST119

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q16864

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q16864

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q16864

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q16864

PeptideAtlas

More...PeptideAtlasi		Q16864

PRoteomics IDEntifications database

More...PRIDEi		Q16864

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		61111 [Q16864-1]
8219

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q16864-1 [Q16864-1]
Q16864-2 [Q16864-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q16864

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q16864

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000128524 Expressed in 112 organ(s), highest expression level in adult mammalian kidney

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q16864 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q16864 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		CAB009529
HPA048700
HPA062011

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		114710, 63 interactors

Protein interaction database and analysis system

More...IntActi		Q16864, 22 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q16864

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the V-ATPase F subunit family.Curated

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00390000013208

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000056545

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q16864

KEGG Orthology (KO)

More...KOi		K02151

Identification of Orthologs from Complete Genome Data

More...OMAi		QNVAEMI

Database of Orthologous Groups

More...OrthoDBi		1483558at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q16864

TreeFam database of animal gene trees

More...TreeFami		TF300080

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.10580, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR008218 ATPase_V1-cplx_f_g_su
IPR005772 ATPase_V1-cplx_fsu_euk
IPR036906 ATPase_V1_fsu_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01990 ATP-synt_F, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF015945 ATPase_V1_F_euk, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF159468 SSF159468, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01101 V_ATP_synt_F, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q16864-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAGRGKLIAV IGDEDTVTGF LLGGIGELNK NRHPNFLVVE KDTTINEIED 
        60         70         80         90        100
TFRQFLNRDD IGIILINQYI AEMVRHALDA HQQSIPAVLE IPSKEHPYDA 
       110 
AKDSILRRAR GMFTAEDLR
Length:119
Mass (Da):13,370
Last modified:February 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9FE5A8BD249A85FA
GO
Isoform 2 (identifier: Q16864-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     52-52: F → FRSLGSLPGSVVEANPNQRDPPLWDEIDS

Note: No experimental confirmation available.
Show »
Length:147
Mass (Da):16,402
Checksum:i964BE12671E7C4DA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti8I → T in BAA08392 (PubMed:8581736).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04834824G → V. Corresponds to variant dbSNP:rs10958Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04595252F → FRSLGSLPGSVVEANPNQRD PPLWDEIDS in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
D49400 mRNA Translation: BAA08392.1
CR456896 mRNA Translation: CAG33177.1
AC025594 Genomic DNA No translation available.
BC104230 mRNA Translation: AAI04231.1
BC104231 mRNA Translation: AAI04232.1
BC107854 mRNA Translation: AAI07855.1
BU956696 mRNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS56511.1 [Q16864-2]
CCDS5807.1 [Q16864-1]

Protein sequence database of the Protein Information Resource

More...PIRi		JC4193

NCBI Reference Sequences

More...RefSeqi		NP_001185838.1, NM_001198909.1 [Q16864-2]
NP_004222.2, NM_004231.3 [Q16864-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000249289; ENSP00000249289; ENSG00000128524 [Q16864-1]
ENST00000492758; ENSP00000417378; ENSG00000128524 [Q16864-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		9296

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:9296

UCSC genome browser

More...UCSCi		uc003voc.3 human [Q16864-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D49400 mRNA Translation: BAA08392.1
CR456896 mRNA Translation: CAG33177.1
AC025594 Genomic DNA No translation available.
BC104230 mRNA Translation: AAI04231.1
BC104231 mRNA Translation: AAI04232.1
BC107854 mRNA Translation: AAI07855.1
BU956696 mRNA No translation available.
CCDSiCCDS56511.1 [Q16864-2]
CCDS5807.1 [Q16864-1]
PIRiJC4193
RefSeqiNP_001185838.1, NM_001198909.1 [Q16864-2]
NP_004222.2, NM_004231.3 [Q16864-1]

3D structure databases

SMRiQ16864
ModBaseiSearch...

Protein-protein interaction databases

BioGridi114710, 63 interactors
IntActiQ16864, 22 interactors

Protein family/group databases

TCDBi3.A.2.2.4 the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily

PTM databases

iPTMnetiQ16864
PhosphoSitePlusiQ16864

Polymorphism and mutation databases

BioMutaiATP6V1F
DMDMi126302612

Proteomic databases

EPDiQ16864
jPOSTiQ16864
MassIVEiQ16864
MaxQBiQ16864
PeptideAtlasiQ16864
PRIDEiQ16864
ProteomicsDBi61111 [Q16864-1]
8219
TopDownProteomicsiQ16864-1 [Q16864-1]
Q16864-2 [Q16864-2]

Genome annotation databases

EnsembliENST00000249289; ENSP00000249289; ENSG00000128524 [Q16864-1]
ENST00000492758; ENSP00000417378; ENSG00000128524 [Q16864-2]
GeneIDi9296
KEGGihsa:9296
UCSCiuc003voc.3 human [Q16864-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		9296
DisGeNETi9296

GeneCards: human genes, protein and diseases

More...GeneCardsi		ATP6V1F
HGNCiHGNC:16832 ATP6V1F
HPAiCAB009529
HPA048700
HPA062011
MIMi607160 gene
neXtProtiNX_Q16864
OpenTargetsiENSG00000128524
PharmGKBiPA38421

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT00390000013208
HOGENOMiHOG000056545
InParanoidiQ16864
KOiK02151
OMAiQNVAEMI
OrthoDBi1483558at2759
PhylomeDBiQ16864
TreeFamiTF300080

Enzyme and pathway databases

BioCyciMetaCyc:HS05192-MONOMER
ReactomeiR-HSA-1222556 ROS and RNS production in phagocytes
R-HSA-77387 Insulin receptor recycling
R-HSA-917977 Transferrin endocytosis and recycling
R-HSA-9639288 Amino acids regulate mTORC1
R-HSA-983712 Ion channel transport

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ATP6V1F human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		ATP6V1F

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		9296
PharosiQ16864

Protein Ontology

More...PROi		PR:Q16864

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000128524 Expressed in 112 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiQ16864 baseline and differential
GenevisibleiQ16864 HS

Family and domain databases

Gene3Di3.40.50.10580, 1 hit
InterProiView protein in InterPro
IPR008218 ATPase_V1-cplx_f_g_su
IPR005772 ATPase_V1-cplx_fsu_euk
IPR036906 ATPase_V1_fsu_sf
PfamiView protein in Pfam
PF01990 ATP-synt_F, 1 hit
PIRSFiPIRSF015945 ATPase_V1_F_euk, 1 hit
SUPFAMiSSF159468 SSF159468, 1 hit
TIGRFAMsiTIGR01101 V_ATP_synt_F, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVATF_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q16864
Secondary accession number(s): C9J2K4, Q6IBA8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 20, 2007
Last modified: November 13, 2019
This is version 167 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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