UniProtKB - Q16720 (AT2B3_HUMAN)
Plasma membrane calcium-transporting ATPase 3
ATP2B3
Functioni
Catalytic activityi
- EC:7.2.2.10
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 473 | 4-aspartylphosphate intermediateBy similarity | 1 | |
Metal bindingi | 794 | MagnesiumBy similarity | 1 | |
Metal bindingi | 798 | MagnesiumBy similarity | 1 |
GO - Molecular functioni
- ATPase-coupled cation transmembrane transporter activity Source: GO_Central
- ATP binding Source: UniProtKB-KW
- calcium ion transmembrane transporter activity Source: SynGO-UCL
- calcium transmembrane transporter activity, phosphorylative mechanism Source: GO_Central
- calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration Source: SynGO
- calmodulin binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
- PDZ domain binding Source: GO_Central
GO - Biological processi
- calcium ion export across plasma membrane Source: SynGO-UCL
- cellular calcium ion homeostasis Source: GO_Central
- ion transmembrane transport Source: Reactome
- regulation of cardiac conduction Source: Reactome
- regulation of cytosolic calcium ion concentration Source: SynGO-UCL
Keywordsi
Molecular function | Calmodulin-binding, Translocase |
Biological process | Calcium transport, Ion transport, Transport |
Ligand | ATP-binding, Calcium, Magnesium, Metal-binding, Nucleotide-binding |
Enzyme and pathway databases
BRENDAi | 3.6.3.8, 2681 |
PathwayCommonsi | Q16720 |
Reactomei | R-HSA-418359, Reduction of cytosolic Ca++ levels R-HSA-5578775, Ion homeostasis R-HSA-936837, Ion transport by P-type ATPases |
Names & Taxonomyi
Protein namesi | Recommended name: Plasma membrane calcium-transporting ATPase 3 (EC:7.2.2.10)Short name: PMCA3 Alternative name(s): Plasma membrane calcium ATPase isoform 3 Plasma membrane calcium pump isoform 3 |
Gene namesi | Name:ATP2B3 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:816, ATP2B3 |
MIMi | 300014, gene |
neXtProti | NX_Q16720 |
VEuPathDBi | HostDB:ENSG00000067842.17 |
Subcellular locationi
Plasma membrane
Extracellular region or secreted
- extracellular vesicle Source: UniProtKB
Plasma Membrane
- plasma membrane Source: SynGO-UCL
Other locations
- GABA-ergic synapse Source: SynGO
- glutamatergic synapse Source: SynGO
- integral component of membrane Source: UniProtKB-KW
- intracellular membrane-bounded organelle Source: GO_Central
- presynapse Source: GOC
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 97 | CytoplasmicSequence analysisAdd BLAST | 97 | |
Transmembranei | 98 – 118 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 119 – 155 | ExtracellularSequence analysisAdd BLAST | 37 | |
Transmembranei | 156 – 176 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 177 – 364 | CytoplasmicSequence analysisAdd BLAST | 188 | |
Transmembranei | 365 – 384 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 385 – 417 | ExtracellularSequence analysisAdd BLAST | 33 | |
Transmembranei | 418 – 435 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 436 – 849 | CytoplasmicSequence analysisAdd BLAST | 414 | |
Transmembranei | 850 – 869 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 870 – 879 | ExtracellularSequence analysis | 10 | |
Transmembranei | 880 – 900 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 901 – 920 | CytoplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 921 – 943 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 944 – 961 | ExtracellularSequence analysisAdd BLAST | 18 | |
Transmembranei | 962 – 983 | HelicalSequence analysisAdd BLAST | 22 | |
Topological domaini | 984 – 1002 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 1003 – 1024 | HelicalSequence analysisAdd BLAST | 22 | |
Topological domaini | 1025 – 1034 | ExtracellularSequence analysis | 10 | |
Transmembranei | 1035 – 1056 | HelicalSequence analysisAdd BLAST | 22 | |
Topological domaini | 1057 – 1220 | CytoplasmicSequence analysisAdd BLAST | 164 |
Keywords - Cellular componenti
Cell membrane, MembranePathology & Biotechi
Involvement in diseasei
Spinocerebellar ataxia, X-linked 1 (SCAX1)1 Publication
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_069308 | 1107 | G → D in SCAX1; the mutant protein is expressed at the plasma membrane but shows impaired extrusion of intracellular calcium with prolonged retention of cytoplasmic calcium compared to wild-type under physiologic conditions. 1 PublicationCorresponds to variant dbSNP:rs397514619EnsemblClinVar. | 1 |
Keywords - Diseasei
Disease variant, NeurodegenerationOrganism-specific databases
DisGeNETi | 492 |
MalaCardsi | ATP2B3 |
MIMi | 302500, phenotype |
OpenTargetsi | ENSG00000067842 |
Orphaneti | 85142, NON RARE IN EUROPE: Aldosterone-producing adenoma 314978, X-linked non progressive cerebellar ataxia |
PharmGKBi | PA25109 |
Miscellaneous databases
Pharosi | Q16720, Tbio |
Chemistry databases
DrugBanki | DB01189, Desflurane DB01159, Halothane |
Genetic variation databases
BioMutai | ATP2B3 |
DMDMi | 116241261 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000046218 | 1 – 1220 | Plasma membrane calcium-transporting ATPase 3Add BLAST | 1220 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 8 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1079 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 1113 | Phosphothreonine; by PKCBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q16720 |
jPOSTi | Q16720 |
MassIVEi | Q16720 |
MaxQBi | Q16720 |
PaxDbi | Q16720 |
PeptideAtlasi | Q16720 |
PRIDEi | Q16720 |
ProteomicsDBi | 61042 [Q16720-1] 61043 [Q16720-2] 61044 [Q16720-3] 61045 [Q16720-4] 61046 [Q16720-5] 61047 [Q16720-6] 61048 [Q16720-7] 61049 [Q16720-8] |
PTM databases
iPTMneti | Q16720 |
PhosphoSitePlusi | Q16720 |
SwissPalmi | Q16720 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000067842, Expressed in endothelial cell and 122 other tissues |
Genevisiblei | Q16720, HS |
Organism-specific databases
HPAi | ENSG00000067842, Group enriched (adrenal gland, brain) |
Interactioni
Subunit structurei
Interacts with PDZD11.
1 PublicationGO - Molecular functioni
- calmodulin binding Source: UniProtKB-KW
- PDZ domain binding Source: GO_Central
Protein-protein interaction databases
BioGRIDi | 106982, 49 interactors |
IntActi | Q16720, 29 interactors |
MINTi | Q16720 |
STRINGi | 9606.ENSP00000263519 |
Miscellaneous databases
RNActi | Q16720, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1097 – 1114 | Calmodulin-binding subdomain ABy similarityAdd BLAST | 18 | |
Regioni | 1115 – 1124 | Calmodulin-binding subdomain BBy similarity | 10 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 297 – 300 | Poly-Glu | 4 | |
Compositional biasi | 1174 – 1179 | Poly-Pro | 6 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0204, Eukaryota |
GeneTreei | ENSGT00940000160765 |
HOGENOMi | CLU_002360_9_0_1 |
InParanoidi | Q16720 |
OMAi | QTEGKWL |
OrthoDBi | 115892at2759 |
PhylomeDBi | Q16720 |
TreeFami | TF300330 |
Family and domain databases
Gene3Di | 3.40.1110.10, 1 hit 3.40.50.1000, 1 hit |
InterProi | View protein in InterPro IPR022141, ATP_Ca_trans_C IPR006068, ATPase_P-typ_cation-transptr_C IPR004014, ATPase_P-typ_cation-transptr_N IPR023299, ATPase_P-typ_cyto_dom_N IPR018303, ATPase_P-typ_P_site IPR023298, ATPase_P-typ_TM_dom_sf IPR008250, ATPase_P-typ_transduc_dom_A_sf IPR036412, HAD-like_sf IPR023214, HAD_sf IPR006408, P-type_ATPase_IIB IPR001757, P_typ_ATPase |
Pfami | View protein in Pfam PF12424, ATP_Ca_trans_C, 1 hit PF00689, Cation_ATPase_C, 1 hit PF00690, Cation_ATPase_N, 1 hit |
SMARTi | View protein in SMART SM00831, Cation_ATPase_N, 1 hit |
SUPFAMi | SSF56784, SSF56784, 1 hit SSF81653, SSF81653, 1 hit SSF81660, SSF81660, 1 hit SSF81665, SSF81665, 1 hit |
TIGRFAMsi | TIGR01517, ATPase-IIB_Ca, 1 hit TIGR01494, ATPase_P-type, 3 hits |
PROSITEi | View protein in PROSITE PS00154, ATPASE_E1_E2, 1 hit |
s (8)i Sequence
Sequence statusi: Complete.
This entry describes 8 produced by isoformsialternative splicing. AlignAdd to basketThis isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGDMANSSIE FHPKPQQQRD VPQAGGFGCT LAELRTLMEL RGAEALQKIE
60 70 80 90 100
EAYGDVSGLC RRLKTSPTEG LADNTNDLEK RRQIYGQNFI PPKQPKTFLQ
110 120 130 140 150
LVWEALQDVT LIILEVAAIV SLGLSFYAPP GEESEACGNV SGGAEDEGEA
160 170 180 190 200
EAGWIEGAAI LLSVICVVLV TAFNDWSKEK QFRGLQSRIE QEQKFTVIRN
210 220 230 240 250
GQLLQVPVAA LVVGDIAQVK YGDLLPADGV LIQANDLKID ESSLTGESDH
260 270 280 290 300
VRKSADKDPM LLSGTHVMEG SGRMVVTAVG VNSQTGIIFT LLGAGGEEEE
310 320 330 340 350
KKDKKGKQQD GAMESSQTKA KKQDGAVAME MQPLKSAEGG EMEEREKKKA
360 370 380 390 400
NAPKKEKSVL QGKLTKLAVQ IGKAGLVMSA ITVIILVLYF VIETFVVEGR
410 420 430 440 450
TWLAECTPVY VQYFVKFFII GVTVLVVAVP EGLPLAVTIS LAYSVKKMMK
460 470 480 490 500
DNNLVRHLDA CETMGNATAI CSDKTGTLTT NRMTVVQSYL GDTHYKEIPA
510 520 530 540 550
PSALTPKILD LLVHAISINS AYTTKILPPE KEGALPRQVG NKTECALLGF
560 570 580 590 600
VLDLKRDFQP VREQIPEDKL YKVYTFNSVR KSMSTVIRMP DGGFRLFSKG
610 620 630 640 650
ASEILLKKCT NILNSNGELR GFRPRDRDDM VRKIIEPMAC DGLRTICIAY
660 670 680 690 700
RDFSAGQEPD WDNENEVVGD LTCIAVVGIE DPVRPEVPEA IRKCQRAGIT
710 720 730 740 750
VRMVTGDNIN TARAIAAKCG IIQPGEDFLC LEGKEFNRRI RNEKGEIEQE
760 770 780 790 800
RLDKVWPKLR VLARSSPTDK HTLVKGIIDS TTGEQRQVVA VTGDGTNDGP
810 820 830 840 850
ALKKADVGFA MGIAGTDVAK EASDIILTDD NFTSIVKAVM WGRNVYDSIS
860 870 880 890 900
KFLQFQLTVN VVAVIVAFTG ACITQDSPLK AVQMLWVNLI MDTFASLALA
910 920 930 940 950
TEPPTESLLL RKPYGRDKPL ISRTMMKNIL GHAVYQLAII FTLLFVGELF
960 970 980 990 1000
FDIDSGRNAP LHSPPSEHYT IIFNTFVMMQ LFNEINARKI HGERNVFDGI
1010 1020 1030 1040 1050
FSNPIFCTIV LGTFGIQIVI VQFGGKPFSC SPLSTEQWLW CLFVGVGELV
1060 1070 1080 1090 1100
WGQVIATIPT SQLKCLKEAG HGPGKDEMTD EELAEGEEEI DHAERELRRG
1110 1120 1130 1140 1150
QILWFRGLNR IQTQIRVVKA FRSSLYEGLE KPESKTSIHN FMATPEFLIN
1160 1170 1180 1190 1200
DYTHNIPLID DTDVDENEER LRAPPPPSPN QNNNAIDSGI YLTTHVTKSA
1210 1220
TSSVFSSSPG SPLHSVETSL
The sequence of this isoform differs from the canonical sequence as follows:
1115-1220: IRVVKAFRSS...SPLHSVETSL → MEVVSTFKRS...AGNPGGESVP
The sequence of this isoform differs from the canonical sequence as follows:
306-319: Missing.
1115-1220: IRVVKAFRSS...SPLHSVETSL → MEVVSTFKRS...AGNPGGESVP
The sequence of this isoform differs from the canonical sequence as follows:
306-319: Missing.
The sequence of this isoform differs from the canonical sequence as follows:
1115-1220: IRVVKAFRSS...SPLHSVETSL → MEVVSTFKRS...NPTSAAGSES
The sequence of this isoform differs from the canonical sequence as follows:
306-319: Missing.
1115-1220: IRVVKAFRSS...SPLHSVETSL → MEVVSTFKRS...NPTSAAGSES
The sequence of this isoform differs from the canonical sequence as follows:
1115-1220: IRVVKAFRSS...SPLHSVETSL → VCWDGKKMLRTTEVG
The sequence of this isoform differs from the canonical sequence as follows:
306-319: Missing.
1115-1220: IRVVKAFRSS...SPLHSVETSL → VCWDGKKMLRTTEVG
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 587 | I → V in AAB09762 (PubMed:8765088).Curated | 1 | |
Sequence conflicti | 587 | I → V in AAB38530 (PubMed:8765088).Curated | 1 | |
Sequence conflicti | 654 | S → Y in AAB09762 (PubMed:8765088).Curated | 1 | |
Sequence conflicti | 654 | S → Y in AAB38530 (PubMed:8765088).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_027928 | 198 | I → M. Corresponds to variant dbSNP:rs2269409Ensembl. | 1 | |
Natural variantiVAR_069308 | 1107 | G → D in SCAX1; the mutant protein is expressed at the plasma membrane but shows impaired extrusion of intracellular calcium with prolonged retention of cytoplasmic calcium compared to wild-type under physiologic conditions. 1 PublicationCorresponds to variant dbSNP:rs397514619EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_000392 | 306 – 319 | Missing in isoform ZA, isoform ZB, isoform ZE and isoform ZG. CuratedAdd BLAST | 14 | |
Alternative sequenceiVSP_000393 | 1115 – 1220 | IRVVK…VETSL → MEVVSTFKRSGSVQGAVRRR SSVLSQLHDVTNLSTPTHAI LSAANPTSAAGNPGGESVP in isoform XA and isoform ZA. 1 PublicationAdd BLAST | 106 | |
Alternative sequenceiVSP_000394 | 1115 – 1220 | IRVVK…VETSL → MEVVSTFKRSGSVQGAVRRR SSVLSQLHDVTNLSTPTHAI LSAANPTSAAGSES in isoform XE and isoform ZE. CuratedAdd BLAST | 106 | |
Alternative sequenceiVSP_000395 | 1115 – 1220 | IRVVK…VETSL → VCWDGKKMLRTTEVG in isoform XG and isoform ZG. CuratedAdd BLAST | 106 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U57971 mRNA Translation: AAB09762.1 U60414 mRNA Translation: AAB38530.1 AH006061 Genomic DNA Translation: AAC15078.1 CH471172 Genomic DNA Translation: EAW72859.1 U82695 Genomic DNA No translation available. U15689 mRNA Translation: AAA60986.1 U15690 mRNA Translation: AAA60987.1 |
CCDSi | CCDS14722.1 [Q16720-2] CCDS35440.1 [Q16720-1] |
RefSeqi | NP_001001344.1, NM_001001344.2 [Q16720-1] NP_068768.2, NM_021949.3 [Q16720-2] XP_005274747.1, XM_005274690.3 [Q16720-1] XP_005274748.1, XM_005274691.3 [Q16720-4] XP_005274749.1, XM_005274692.3 [Q16720-2] |
Genome annotation databases
Ensembli | ENST00000263519; ENSP00000263519; ENSG00000067842 [Q16720-1] ENST00000349466; ENSP00000343886; ENSG00000067842 [Q16720-1] ENST00000359149; ENSP00000352062; ENSG00000067842 [Q16720-2] ENST00000370186; ENSP00000359205; ENSG00000067842 [Q16720-3] ENST00000393842; ENSP00000377425; ENSG00000067842 [Q16720-6] |
GeneIDi | 492 |
KEGGi | hsa:492 |
UCSCi | uc004fhs.2, human [Q16720-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U57971 mRNA Translation: AAB09762.1 U60414 mRNA Translation: AAB38530.1 AH006061 Genomic DNA Translation: AAC15078.1 CH471172 Genomic DNA Translation: EAW72859.1 U82695 Genomic DNA No translation available. U15689 mRNA Translation: AAA60986.1 U15690 mRNA Translation: AAA60987.1 |
CCDSi | CCDS14722.1 [Q16720-2] CCDS35440.1 [Q16720-1] |
RefSeqi | NP_001001344.1, NM_001001344.2 [Q16720-1] NP_068768.2, NM_021949.3 [Q16720-2] XP_005274747.1, XM_005274690.3 [Q16720-1] XP_005274748.1, XM_005274691.3 [Q16720-4] XP_005274749.1, XM_005274692.3 [Q16720-2] |
3D structure databases
SMRi | Q16720 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 106982, 49 interactors |
IntActi | Q16720, 29 interactors |
MINTi | Q16720 |
STRINGi | 9606.ENSP00000263519 |
Chemistry databases
DrugBanki | DB01189, Desflurane DB01159, Halothane |
PTM databases
iPTMneti | Q16720 |
PhosphoSitePlusi | Q16720 |
SwissPalmi | Q16720 |
Genetic variation databases
BioMutai | ATP2B3 |
DMDMi | 116241261 |
Proteomic databases
EPDi | Q16720 |
jPOSTi | Q16720 |
MassIVEi | Q16720 |
MaxQBi | Q16720 |
PaxDbi | Q16720 |
PeptideAtlasi | Q16720 |
PRIDEi | Q16720 |
ProteomicsDBi | 61042 [Q16720-1] 61043 [Q16720-2] 61044 [Q16720-3] 61045 [Q16720-4] 61046 [Q16720-5] 61047 [Q16720-6] 61048 [Q16720-7] 61049 [Q16720-8] |
Protocols and materials databases
Antibodypediai | 443, 67 antibodies |
Genome annotation databases
Ensembli | ENST00000263519; ENSP00000263519; ENSG00000067842 [Q16720-1] ENST00000349466; ENSP00000343886; ENSG00000067842 [Q16720-1] ENST00000359149; ENSP00000352062; ENSG00000067842 [Q16720-2] ENST00000370186; ENSP00000359205; ENSG00000067842 [Q16720-3] ENST00000393842; ENSP00000377425; ENSG00000067842 [Q16720-6] |
GeneIDi | 492 |
KEGGi | hsa:492 |
UCSCi | uc004fhs.2, human [Q16720-1] |
Organism-specific databases
CTDi | 492 |
DisGeNETi | 492 |
GeneCardsi | ATP2B3 |
HGNCi | HGNC:816, ATP2B3 |
HPAi | ENSG00000067842, Group enriched (adrenal gland, brain) |
MalaCardsi | ATP2B3 |
MIMi | 300014, gene 302500, phenotype |
neXtProti | NX_Q16720 |
OpenTargetsi | ENSG00000067842 |
Orphaneti | 85142, NON RARE IN EUROPE: Aldosterone-producing adenoma 314978, X-linked non progressive cerebellar ataxia |
PharmGKBi | PA25109 |
VEuPathDBi | HostDB:ENSG00000067842.17 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0204, Eukaryota |
GeneTreei | ENSGT00940000160765 |
HOGENOMi | CLU_002360_9_0_1 |
InParanoidi | Q16720 |
OMAi | QTEGKWL |
OrthoDBi | 115892at2759 |
PhylomeDBi | Q16720 |
TreeFami | TF300330 |
Enzyme and pathway databases
BRENDAi | 3.6.3.8, 2681 |
PathwayCommonsi | Q16720 |
Reactomei | R-HSA-418359, Reduction of cytosolic Ca++ levels R-HSA-5578775, Ion homeostasis R-HSA-936837, Ion transport by P-type ATPases |
Miscellaneous databases
BioGRID-ORCSi | 492, 7 hits in 500 CRISPR screens |
ChiTaRSi | ATP2B3, human |
GeneWikii | ATP2B3 |
GenomeRNAii | 492 |
Pharosi | Q16720, Tbio |
PROi | PR:Q16720 |
RNActi | Q16720, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000067842, Expressed in endothelial cell and 122 other tissues |
Genevisiblei | Q16720, HS |
Family and domain databases
Gene3Di | 3.40.1110.10, 1 hit 3.40.50.1000, 1 hit |
InterProi | View protein in InterPro IPR022141, ATP_Ca_trans_C IPR006068, ATPase_P-typ_cation-transptr_C IPR004014, ATPase_P-typ_cation-transptr_N IPR023299, ATPase_P-typ_cyto_dom_N IPR018303, ATPase_P-typ_P_site IPR023298, ATPase_P-typ_TM_dom_sf IPR008250, ATPase_P-typ_transduc_dom_A_sf IPR036412, HAD-like_sf IPR023214, HAD_sf IPR006408, P-type_ATPase_IIB IPR001757, P_typ_ATPase |
Pfami | View protein in Pfam PF12424, ATP_Ca_trans_C, 1 hit PF00689, Cation_ATPase_C, 1 hit PF00690, Cation_ATPase_N, 1 hit |
SMARTi | View protein in SMART SM00831, Cation_ATPase_N, 1 hit |
SUPFAMi | SSF56784, SSF56784, 1 hit SSF81653, SSF81653, 1 hit SSF81660, SSF81660, 1 hit SSF81665, SSF81665, 1 hit |
TIGRFAMsi | TIGR01517, ATPase-IIB_Ca, 1 hit TIGR01494, ATPase_P-type, 3 hits |
PROSITEi | View protein in PROSITE PS00154, ATPASE_E1_E2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | AT2B3_HUMAN | |
Accessioni | Q16720Primary (citable) accession number: Q16720 Secondary accession number(s): B7WNR8 Q16858 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | October 17, 2006 | |
Last modified: | February 10, 2021 | |
This is version 202 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome X
Human chromosome X: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families