UniProtKB - Q166A7 (KGUA_ROSDO)
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Protein
Guanylate kinase
Gene
gmk
Organism
Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)
Status
Functioni
Essential for recycling GMP and indirectly, cGMP.UniRule annotation
Catalytic activityi
ATP + GMP = ADP + GDP.UniRule annotation
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 11 – 18 | ATPUniRule annotation | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- guanylate kinase activity Source: UniProtKB-EC
Keywordsi
Molecular function | Kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)Alternative name(s): GMP kinaseUniRule annotation |
Gene namesi | Name:gmkUniRule annotation Ordered Locus Names:RD1_2638 |
Organismi | Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) |
Taxonomic identifieri | 375451 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Roseobacter › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000266390 | 1 – 211 | Guanylate kinaseAdd BLAST | 211 |
Structurei
3D structure databases
ProteinModelPortali | Q166A7. |
SMRi | Q166A7. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 184 | Guanylate kinase-likeUniRule annotationAdd BLAST | 181 |
Sequence similaritiesi
Belongs to the guanylate kinase family.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG4108UHA. Bacteria. COG0194. LUCA. |
HOGENOMi | HOG000037638. |
KOi | K00942. |
OMAi | AGNYYGT. |
OrthoDBi | POG091H01Q4. |
Family and domain databases
HAMAPi | MF_00328. Guanylate_kinase. 1 hit. |
InterProi | View protein in InterPro IPR008145. GK/Ca_channel_bsu. IPR008144. Guanylate_kin-like_dom. IPR017665. Guanylate_kinase. IPR020590. Guanylate_kinase_CS. IPR027417. P-loop_NTPase. |
Pfami | View protein in Pfam PF00625. Guanylate_kin. 1 hit. |
SMARTi | View protein in SMART SM00072. GuKc. 1 hit. |
SUPFAMi | SSF52540. SSF52540. 1 hit. |
TIGRFAMsi | TIGR03263. guanyl_kin. 1 hit. |
PROSITEi | View protein in PROSITE PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q166A7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRRGLLIILS SPSGAGKSTL ARRLRDWDTD IEFSVSATTR AARPGEVDGR
60 70 80 90 100
EYHFVDEAAF KSQVSNGGML EHAHVFGNFY GSPSGPVQEA INAGRDVLFD
110 120 130 140 150
IDWQGAQQIT NSALSAHTLS IFLLPPSIRE LRNRLEKRAQ DDAATIARRM
160 170 180 190 200
DKSWDEISHW GSYDYVLVND DLDTTEAHLK TIVTATRLRR SQQPGLTEHV
210
RHLQSEFERL S
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000362 Genomic DNA. Translation: ABG32186.1. |
Genome annotation databases
EnsemblBacteriai | ABG32186; ABG32186; RD1_2638. |
KEGGi | rde:RD1_2638. |
Similar proteinsi
Entry informationi
Entry namei | KGUA_ROSDO | |
Accessioni | Q166A7Primary (citable) accession number: Q166A7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 12, 2006 |
Last sequence update: | July 25, 2006 | |
Last modified: | March 28, 2018 | |
This is version 73 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |