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1 to 25 of 106  Show
  1. 1
    "Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity."
    Gallo K.A., Mark M.R., Scadden D.T., Wang Z., Gu Q., Godowski P.J.
    J. Biol. Chem. 269:15092-15100(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, CATALYTIC ACTIVITY, TISSUE SPECIFICITY, AUTOPHOSPHORYLATION, MUTAGENESIS OF LYS-144 AND GLU-164.
    Category: Function, Pathology & Biotech, PTM / Processing, Expression, Sequences.
    Tissue: Megakaryocyte.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain."
    Ing Y.L., Leung I.W.L., Heng H.H.Q., Tsui L.-C., Lassam N.J.
    Oncogene 9:1745-1750(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
    Category: Expression, Sequences.
    Tissue: Thymus.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12931 other entries.

  4. 4
    Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Liver and Spleen.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4270 other entries.

  6. 6
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT HIS-252.
    Category: Sequences.
    Tissue: Brain and Hippocampus.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50471 other entries.

  7. 7
    "MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6."
    Tibbles L.A., Ing Y.L., Kiefer F., Chan J., Iscove N., Woodgett J.R., Lassam N.J.
    EMBO J. 15:7026-7035(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH MAP2K4/MKK4, FUNCTION IN PHOSPHORYLATION OF MAP2K4/MKK4.
    Category: Function, PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  8. 8
    "Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3."
    Leung I.W.L., Lassam N.J.
    J. Biol. Chem. 273:32408-32415(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACTIVITY REGULATION, HOMODIMERIZATION.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).
  9. 9
    "The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation."
    Leung I.W.L., Lassam N.J.
    J. Biol. Chem. 276:1961-1967(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACTIVITY REGULATION, PHOSPHORYLATION AT THR-277 AND SER-281, MUTAGENESIS OF LYS-144; THR-277; THR-278 AND SER-281.
    Category: Function, Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).
  10. 10
    "Identification of in vivo phosphorylation sites of MLK3 by mass spectrometry and phosphopeptide mapping."
    Vacratsis P.O., Phinney B.S., Gage D.A., Gallo K.A.
    Biochemistry 41:5613-5624(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION AT SER-524; SER-555; SER-556; SER-654; SER-705; SER-724; SER-727; SER-740; SER-758; SER-770 AND SER-793.
    Category: PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 4 other entries.

  11. 11
    "A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization."
    Swenson K.I., Winkler K.E., Means A.R.
    Mol. Biol. Cell 14:156-172(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
    Category: Function, Subcellular Location.
    Source: UniProtKB/Swiss-Prot (reviewed).
  12. 12
    "MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation."
    Chadee D.N., Kyriakis J.M.
    Nat. Cell Biol. 6:770-776(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 14 other entries.

  13. 13
    "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
    Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
    Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-507, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1240 other entries.

  14. 14
    "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
    Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
    Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11; SER-507; SER-548; SER-705; THR-708; SER-748; SER-758; SER-793 AND SER-815, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2445 other entries.

  15. 15
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-789 AND SER-793, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 8732 other entries.

  16. 16
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-394; SER-507; SER-548; SER-693; SER-705; SER-748; SER-758; SER-789 AND SER-793, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1396 other entries.

  17. 17
    "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-789 AND SER-793, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Tissue: Leukemic T-cell.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5549 other entries.

  18. 18
    "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-507; SER-524 AND SER-548, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 13322 other entries.

  19. 19
    "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 11543 other entries.

  20. 20
    Category: Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 452 other entries.

  21. 21
    "Active Ras induces heterodimerization of cRaf and BRaf."
    Weber C.K., Slupsky J.R., Kalmes H.A., Rapp U.R.
    Cancer Res. 61:3595-3598(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-449607.

    This publication is mapped to 24 other entries.

  22. 22
    "Role of MLK3-mediated activation of p70 S6 kinase in Rac1 transformation."
    Lambert J.M., Karnoub A.E., Graves L.M., Campbell S.L., Der C.J.
    J. Biol. Chem. 277:4770-4777(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: MLK3 may be a negative regulator of the growth-promoting and transforming properties of Rac1Imported.
    Source: GeneRIF:4296.

    This publication is mapped to 12 other entries.

  23. 23
    "Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2."
    Chadee D.N., Yuasa T., Kyriakis J.M.
    Mol. Cell. Biol. 22:737-749(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:Q16584.

    This publication is cited by 2 and mapped to 2 other entries.

  24. 24
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-449607.

    This publication is mapped to 43 other entries.

  25. 25
    "Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival."
    Barthwal M.K., Sathyanarayana P., Kundu C.N., Rana B., Pradeep A., Sharma C., Woodgett J.R., Rana A.
    J. Biol. Chem. 278:3897-3902(2003) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: PhosphorylationImported, negative regulation by protein kinase B leads to cell survivalImported.
    Source: GeneRIF:4296, iPTMnet:Q16584, PhosphoSitePlus:Q16584.

    This publication is mapped to 8 other entries.

1 to 25 of 106  Show
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