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Protein

Na(+)/H(+) antiporter NhaA 1

Gene

nhaA1

Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Na+/H+ antiporter that extrudes sodium in exchange for external protons.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAntiport, Ion transport, Sodium transport, Transport
LigandSodium

Enzyme and pathway databases

BioCyciPATL342610:G1G6R-4288-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Na(+)/H(+) antiporter NhaA 1UniRule annotation
Alternative name(s):
Sodium/proton antiporter NhaA 1UniRule annotation
Gene namesi
Name:nhaA1UniRule annotation
Ordered Locus Names:Patl_4144
OrganismiPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Taxonomic identifieri342610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
Proteomesi
  • UP000001981 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 54HelicalUniRule annotationAdd BLAST21
Transmembranei73 – 95HelicalUniRule annotationAdd BLAST23
Transmembranei116 – 136HelicalUniRule annotationAdd BLAST21
Transmembranei146 – 166HelicalUniRule annotationAdd BLAST21
Transmembranei175 – 195HelicalUniRule annotationAdd BLAST21
Transmembranei203 – 223HelicalUniRule annotationAdd BLAST21
Transmembranei227 – 247HelicalUniRule annotationAdd BLAST21
Transmembranei324 – 344HelicalUniRule annotationAdd BLAST21
Transmembranei353 – 373HelicalUniRule annotationAdd BLAST21
Transmembranei394 – 414HelicalUniRule annotationAdd BLAST21
Transmembranei428 – 448HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003343651 – 472Na(+)/H(+) antiporter NhaA 1Add BLAST472

Interactioni

Protein-protein interaction databases

STRINGi342610.Patl_4144

Structurei

3D structure databases

ProteinModelPortaliQ15N95
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DRC Bacteria
COG3004 LUCA
HOGENOMiHOG000218489
KOiK03313
OMAiLHHWVND
OrthoDBiPOG091H05CU

Family and domain databases

Gene3Di1.20.1530.10, 2 hits
HAMAPiMF_01844 NhaA, 1 hit
InterProiView protein in InterPro
IPR023171 Na/H_antiporter_dom_sf
IPR004670 NhaA
PANTHERiPTHR30341 PTHR30341, 1 hit
PfamiView protein in Pfam
PF06965 Na_H_antiport_1, 1 hit
TIGRFAMsiTIGR00773 NhaA, 1 hit

Sequencei

Sequence statusi: Complete.

Q15N95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQLQDKDRE LAPLERKFNH FICSFEQFFK SQATASITLL LAAIAAMVIA
60 70 80 90 100
NSQWHEGYEE ISHMAFSISL GDFAISHSLH TWVNDGLMVL FFFLLGLEIK
110 120 130 140 150
YECLVGDLKD FRDSSLVIAM AIGGMLLPAG IYAGVALTGV DEALRGWGIP
160 170 180 190 200
MATDTAFALG ILALLGSKAP RSAAVTLSAL AIVDDMGAVA VIGLFYTENI
210 220 230 240 250
HLTSLMYAGL TLGGLFALNV LGFRRPIFYL VGGILLWWFV LQSGVHATAA
260 270 280 290 300
GILAALAVPT KPYAQSTWFA TNMRSVLNRF EKNDRKDKSI LEQQDQHELV
310 320 330 340 350
EQAQDIAAMT TTPIQRWGHV LNRPVSLIIL PIFAFINAGV ALPDDLSKIF
360 370 380 390 400
DSVVFIGVAS AMVLGKVIGI SVFAWIAVKS GFSRLPNGLA FGHVFALACL
410 420 430 440 450
AGVGFTMSLF IASLGFAGHP ELLAQAKLGI LAGSVIAAII GTTLFLMIKH
460 470
KVHEEPKDER HNKAGLPQTD QE
Length:472
Mass (Da):51,017
Last modified:July 25, 2006 - v1
Checksum:i3E184DFBAC298A43
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000388 Genomic DNA Translation: ABG42643.1
RefSeqiWP_011576836.1, NC_008228.1

Genome annotation databases

EnsemblBacteriaiABG42643; ABG42643; Patl_4144
KEGGipat:Patl_4144

Similar proteinsi

Entry informationi

Entry nameiNHAA1_PSEA6
AccessioniPrimary (citable) accession number: Q15N95
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 25, 2006
Last modified: July 18, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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