Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 72 (29 Sep 2021)
Sequence version 1 (25 Jul 2006)
Previous versions | rss
Add a publicationFeedback
Protein

Catalase

Gene
N/A
Organism
Cryptococcus neoformans (Filobasidiella neoformans)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

UniRule annotationARBA annotation

Serves to protect cells from the toxic effects of hydrogen peroxide.

UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

hemeUniRule annotationARBA annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei82UniRule annotation1
Active sitei155UniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi369Iron (heme axial ligand)UniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxideUniRule annotationARBA annotation
LigandHemeUniRule annotationARBA annotation, Iron, Metal-binding

Protein family/group databases

PeroxiBase, a peroxidase database

More...
PeroxiBasei
5222, CnKat03_H99

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CatalaseUniRule annotationARBA annotation (EC:1.11.1.6UniRule annotationARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCryptococcus neoformans (Filobasidiella neoformans)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5207 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesCryptococcaceaeCryptococcusCryptococcus neoformans species complex

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:CKF44_00575
FungiDB:CNA05600
FungiDB:CNAG_00575
FungiDB:CNBA5410

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 422CatalaseInterPro annotationAdd BLAST388

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the catalase family.UniRule annotationARBA annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03132, GATase1_catalase, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1370.20, 1 hit
3.40.50.880, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018028, Catalase
IPR024708, Catalase_AS
IPR024712, Catalase_clade2
IPR043156, Catalase_clade2_helical
IPR011614, Catalase_core
IPR002226, Catalase_haem_BS
IPR010582, Catalase_immune_responsive
IPR041399, Catalase_large_C
IPR020835, Catalase_sf
IPR029062, Class_I_gatase-like

The PANTHER Classification System

More...
PANTHERi
PTHR42821, PTHR42821, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00199, Catalase, 1 hit
PF06628, Catalase-rel, 1 hit
PF18011, Catalase_C, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF038927, Catalase_clade2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00067, CATALASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01060, Catalase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52317, SSF52317, 1 hit
SSF56634, SSF56634, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00437, CATALASE_1, 1 hit
PS00438, CATALASE_2, 1 hit
PS51402, CATALASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q15EU5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQMLNQAAN MVTGDAKYRQ MAENTIDQDD KTPYTTYFGV KVSDTDNSLR
60 70 80 90 100
AGARGPTLLE DFHNREKIQH FDHERIPERV VHARGAGAFG EFKLHTPLTD
110 120 130 140 150
ITTAKVLTDT SKVVPAYVRF SAVAGFRGSA DTVRDVRGFA TRFYTDEGNW
160 170 180 190 200
DIVGNNMPVF FINDAIKFPD VIHAVQPEPH NQIPQAQTAH DNAWDFMSLH
210 220 230 240 250
KPALHMQQWL TSDRAVPRSY RMMQGFGVHT FRLINEEGKS TFVKYHWIPH
260 270 280 290 300
LGTHSLVWDE ALKVAGQDPD FHRRDLWDAI EVGAYPKWDL GVQLIKEEDE
310 320 330 340 350
HKFDFDLLDA TKLIPEELVP VQKIGTLTLN RNPVDYFSEV EQVAFCTQHI
360 370 380 390 400
VPGMDFTDDP LLAGRNFSYP DTQVSRLGIN WKDIPVNRPI CPFMTTMREG
410 420 430 440 450
QMSMFSKNNR TPYHPNRNEN LPLTSPKQGG FKSYPAKVSG IKERVQAPKF
460 470 480 490 500
NDHSSQATLF WNSMSDVEKK HIIDAYKFEL SHCADNLVIQ NVINRINEID
510 520 530 540 550
HGLATAVHSG FPHLSLPEAK PNHGKRTEYL SQITGKNQTF TAAGRKIGIF
560 570 580 590 600
LVPGFVYSQV APLLAAFEAA GCMVKFVGPT LGPVKASDGQ SFTTEFTFEG
610 620 630 640 650
CRSTYFDALI FAGGPDDAFV SKLKIGRLIH AAREAYMHLK AIGAVGNATQ
660 670 680 690 700
WLVETCIPGD FSPTVKTESS VVQENGVVFA PANPTLHSAQ FAKQFLETVA
710
NHRVWDREVS HIAA
Length:714
Mass (Da):80,035
Last modified:July 25, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9661106410C5288A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ468111 Genomic DNA Translation: ABG26354.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ468111 Genomic DNA Translation: ABG26354.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

PeroxiBasei5222, CnKat03_H99

Organism-specific databases

VEuPathDBiFungiDB:CKF44_00575
FungiDB:CNA05600
FungiDB:CNAG_00575
FungiDB:CNBA5410

Family and domain databases

CDDicd03132, GATase1_catalase, 1 hit
Gene3Di1.20.1370.20, 1 hit
3.40.50.880, 1 hit
InterProiView protein in InterPro
IPR018028, Catalase
IPR024708, Catalase_AS
IPR024712, Catalase_clade2
IPR043156, Catalase_clade2_helical
IPR011614, Catalase_core
IPR002226, Catalase_haem_BS
IPR010582, Catalase_immune_responsive
IPR041399, Catalase_large_C
IPR020835, Catalase_sf
IPR029062, Class_I_gatase-like
PANTHERiPTHR42821, PTHR42821, 1 hit
PfamiView protein in Pfam
PF00199, Catalase, 1 hit
PF06628, Catalase-rel, 1 hit
PF18011, Catalase_C, 1 hit
PIRSFiPIRSF038927, Catalase_clade2, 1 hit
PRINTSiPR00067, CATALASE
SMARTiView protein in SMART
SM01060, Catalase, 1 hit
SUPFAMiSSF52317, SSF52317, 1 hit
SSF56634, SSF56634, 1 hit
PROSITEiView protein in PROSITE
PS00437, CATALASE_1, 1 hit
PS00438, CATALASE_2, 1 hit
PS51402, CATALASE_3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ15EU5_CRYNE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q15EU5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: September 29, 2021
This is version 72 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again