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Entry version 150 (18 Sep 2019)
Sequence version 2 (30 Nov 2010)
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Protein

Tubulin-specific chaperone C

Gene

TBCC

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Tubulin-folding protein; involved in the final step of the tubulin folding pathway.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-389977 Post-chaperonin tubulin folding pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tubulin-specific chaperone C
Alternative name(s):
Tubulin-folding cofactor C
Short name:
CFC
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TBCC
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:11580 TBCC

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
602971 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q15814

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi262R → A: Inhibits stimulation of tubulin GTPase activity. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
6903

Open Targets

More...
OpenTargetsi
ENSG00000124659

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36344

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q15814

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TBCC

Domain mapping of disease mutations (DMDM)

More...
DMDMi
313104020

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000800461 – 346Tubulin-specific chaperone CAdd BLAST346

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei80PhosphoserineCombined sources1
Modified residuei168PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q15814

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q15814

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q15814

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q15814

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q15814

PeptideAtlas

More...
PeptideAtlasi
Q15814

PRoteomics IDEntifications database

More...
PRIDEi
Q15814

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
60773

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q15814

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q15814

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecting cilium at the tips of the IS (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000124659 Expressed in 216 organ(s), highest expression level in oocyte

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q15814 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035073
HPA035074

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112766, 2 interactors

Database of interacting proteins

More...
DIPi
DIP-46388N

Protein interaction database and analysis system

More...
IntActi
Q15814, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000361967

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1346
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q15814

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q15814

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini171 – 323C-CAP/cofactor C-likePROSITE-ProRule annotationAdd BLAST153

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TBCC family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2512 Eukaryota
ENOG410Y28B LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162058

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000030935

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q15814

KEGG Orthology (KO)

More...
KOi
K21766

Identification of Orthologs from Complete Genome Data

More...
OMAi
CQQLRLH

Database of Orthologous Groups

More...
OrthoDBi
1618114at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q15814

TreeFam database of animal gene trees

More...
TreeFami
TF105832

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.58.1250, 1 hit
2.160.20.70, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017901 C-CAP_CF_C-like
IPR016098 CAP/MinC_C
IPR006599 CARP_motif
IPR027684 TBCC
IPR031925 TBCC_N
IPR038397 TBCC_N_sf
IPR012945 Tubulin-bd_cofactor_C_dom

The PANTHER Classification System

More...
PANTHERi
PTHR15139 PTHR15139, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07986 TBCC, 1 hit
PF16752 TBCC_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037947 Protein_XRP2_, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00673 CARP, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51329 C_CAP_COFACTOR_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q15814-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESVSCSAAA VRTGDMESQR DLSLVPERLQ RREQERQLEV ERRKQKRQNQ
60 70 80 90 100
EVEKENSHFF VATFVRERAA VEELLERAES VERLEEAASR LQGLQKLIND
110 120 130 140 150
SVFFLAAYDL RQGQEALARL QAALAERRRG LQPKKRFAFK TRGKDAASST
160 170 180 190 200
KVDAAPGIPP AVESIQDSPL PKKAEGDLGP SWVCGFSNLE SQVLEKRASE
210 220 230 240 250
LHQRDVLLTE LSNCTVRLYG NPNTLRLTKA HSCKLLCGPV STSVFLEDCS
260 270 280 290 300
DCVLAVACQQ LRIHSTKDTR IFLQVTSRAI VEDCSGIQFA PYTWSYPEID
310 320 330 340
KDFESSGLDR SKNNWNDVDD FNWLARDMAS PNWSILPEEE RNIQWD
Length:346
Mass (Da):39,248
Last modified:November 30, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i32732BB3411FCD20
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02682265V → A4 PublicationsCorresponds to variant dbSNP:rs2234026Ensembl.1
Natural variantiVAR_06742386E → D1 PublicationCorresponds to variant dbSNP:rs144361927Ensembl.1
Natural variantiVAR_026823157G → D. Corresponds to variant dbSNP:rs7742995Ensembl.1
Natural variantiVAR_020448169P → S. Corresponds to variant dbSNP:rs2234027Ensembl.1
Natural variantiVAR_024653180P → S. Corresponds to variant dbSNP:rs2234028Ensembl.1
Natural variantiVAR_026824279A → T. Corresponds to variant dbSNP:rs12175072Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U61234 mRNA Translation: AAB17539.1
BT007002 mRNA Translation: AAP35648.1
AK312681 mRNA Translation: BAG35561.1
AL353716 Genomic DNA No translation available.
BC017479 mRNA Translation: AAH17479.1
BC020170 mRNA Translation: AAH20170.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4872.1

NCBI Reference Sequences

More...
RefSeqi
NP_003183.1, NM_003192.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000372876; ENSP00000361967; ENSG00000124659

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6903

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6903

UCSC genome browser

More...
UCSCi
uc003osl.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U61234 mRNA Translation: AAB17539.1
BT007002 mRNA Translation: AAP35648.1
AK312681 mRNA Translation: BAG35561.1
AL353716 Genomic DNA No translation available.
BC017479 mRNA Translation: AAH17479.1
BC020170 mRNA Translation: AAH20170.1
CCDSiCCDS4872.1
RefSeqiNP_003183.1, NM_003192.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2L3LNMR-A26-135[»]
2YUHNMR-A181-346[»]
SMRiQ15814
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi112766, 2 interactors
DIPiDIP-46388N
IntActiQ15814, 2 interactors
STRINGi9606.ENSP00000361967

PTM databases

iPTMnetiQ15814
PhosphoSitePlusiQ15814

Polymorphism and mutation databases

BioMutaiTBCC
DMDMi313104020

Proteomic databases

EPDiQ15814
jPOSTiQ15814
MassIVEiQ15814
MaxQBiQ15814
PaxDbiQ15814
PeptideAtlasiQ15814
PRIDEiQ15814
ProteomicsDBi60773

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6903

Genome annotation databases

EnsembliENST00000372876; ENSP00000361967; ENSG00000124659
GeneIDi6903
KEGGihsa:6903
UCSCiuc003osl.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6903
DisGeNETi6903

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TBCC
HGNCiHGNC:11580 TBCC
HPAiHPA035073
HPA035074
MIMi602971 gene
neXtProtiNX_Q15814
OpenTargetsiENSG00000124659
PharmGKBiPA36344

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2512 Eukaryota
ENOG410Y28B LUCA
GeneTreeiENSGT00940000162058
HOGENOMiHOG000030935
InParanoidiQ15814
KOiK21766
OMAiCQQLRLH
OrthoDBi1618114at2759
PhylomeDBiQ15814
TreeFamiTF105832

Enzyme and pathway databases

ReactomeiR-HSA-389977 Post-chaperonin tubulin folding pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TBCC human
EvolutionaryTraceiQ15814

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
6903
PharosiQ15814

Protein Ontology

More...
PROi
PR:Q15814

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000124659 Expressed in 216 organ(s), highest expression level in oocyte
GenevisibleiQ15814 HS

Family and domain databases

Gene3Di1.20.58.1250, 1 hit
2.160.20.70, 1 hit
InterProiView protein in InterPro
IPR017901 C-CAP_CF_C-like
IPR016098 CAP/MinC_C
IPR006599 CARP_motif
IPR027684 TBCC
IPR031925 TBCC_N
IPR038397 TBCC_N_sf
IPR012945 Tubulin-bd_cofactor_C_dom
PANTHERiPTHR15139 PTHR15139, 1 hit
PfamiView protein in Pfam
PF07986 TBCC, 1 hit
PF16752 TBCC_N, 1 hit
PIRSFiPIRSF037947 Protein_XRP2_, 1 hit
SMARTiView protein in SMART
SM00673 CARP, 2 hits
PROSITEiView protein in PROSITE
PS51329 C_CAP_COFACTOR_C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTBCC_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q15814
Secondary accession number(s): Q53Y43, Q5T787
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 30, 2010
Last modified: September 18, 2019
This is version 150 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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