LTB4R

Functionⁱ

Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

GO - Molecular functionⁱ

galanin receptor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
G protein-coupled peptide receptor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
leukotriene B4 receptor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
leukotriene receptor activity
Source: ProtInc
Traceable author statementⁱ
- 9177352
nucleotide binding
Source: ProtInc
Traceable author statementⁱ
- 8702478

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

G protein-coupled receptor signaling pathway Source: Reactome
immune response
Source: ProtInc
Traceable author statementⁱ
- 9177352
inflammatory response
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
muscle contraction
Source: ProtInc
Traceable author statementⁱ
- 8702478
neuropeptide signaling pathway
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
phospholipase C-activating G protein-coupled receptor signaling pathway
Source: ProtInc
Traceable author statementⁱ
- 8702478

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptor, Receptor, Transducer

Molecular function

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactomeⁱ	R-HSA-391906 Leukotriene receptors R-HSA-416476 G alpha (q) signalling events
SIGNORⁱ	Q15722

Protein family/group databases

TCDBⁱ

9.A.14.13.5 the g-protein-coupled receptor (gpcr) family

Chemistry databases

SwissLipidsⁱ	SLP:000001555

SwissLipidsⁱ

SLP:000001555

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Leukotriene B4 receptor 1 Short name: LTB4-R 1 Short name: LTB4-R1 Alternative name(s): Chemoattractant receptor-like 1 G-protein coupled receptor 16 P2Y purinoceptor 7 Short name: P2Y7
Gene namesⁱ	Name:LTB4R Synonyms:BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 14

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000213903.8
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:6713 LTB4R
MIMⁱ	601531 gene
neXtProtⁱ	NX_Q15722

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 19	ExtracellularSequence analysisAdd BLAST	19
Transmembraneⁱ	20 – 42	Helical; Name=1Sequence analysisAdd BLAST	23
Topological domainⁱ	43 – 54	CytoplasmicSequence analysisAdd BLAST	12
Transmembraneⁱ	55 – 75	Helical; Name=2Sequence analysisAdd BLAST	21
Topological domainⁱ	76 – 91	ExtracellularSequence analysisAdd BLAST	16
Transmembraneⁱ	92 – 113	Helical; Name=3Sequence analysisAdd BLAST	22
Topological domainⁱ	114 – 138	CytoplasmicSequence analysisAdd BLAST	25
Transmembraneⁱ	139 – 159	Helical; Name=4Sequence analysisAdd BLAST	21
Topological domainⁱ	160 – 178	ExtracellularSequence analysisAdd BLAST	19
Transmembraneⁱ	179 – 199	Helical; Name=5Sequence analysisAdd BLAST	21
Topological domainⁱ	200 – 221	CytoplasmicSequence analysisAdd BLAST	22
Transmembraneⁱ	222 – 242	Helical; Name=6Sequence analysisAdd BLAST	21
Topological domainⁱ	243 – 268	ExtracellularSequence analysisAdd BLAST	26
Transmembraneⁱ	269 – 289	Helical; Name=7Sequence analysisAdd BLAST	21
Topological domainⁱ	290 – 352	CytoplasmicSequence analysisAdd BLAST	63

Keywords - Cellular componentⁱ

Cell membrane, Membrane

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Mutagenesisⁱ	308	T → P or A: No effect on affinity for leukotriene B4, induces resistance to desensitization by GRK6, but minor effect on phosphorylation by GRK6. 1 Publication		1
Mutagenesisⁱ	310	S → A: No effect on affinity for leukotriene B4 or on desensitization by GRK6. 1 Publication		1

Organism-specific databases

DisGeNET More...DisGeNETⁱ	1241
Open Targets More...OpenTargetsⁱ	ENSG00000213903
PharmGKBⁱ	PA30476

Chemistry databases

ChEMBLⁱ	CHEMBL3911
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	267

Polymorphism and mutation databases

BioMutaⁱ	LTB4R
DMDMⁱ	3041713

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000069708	1 – 352	Leukotriene B4 receptor 1Add BLAST		352

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Glycosylationⁱ	2	N-linked (GlcNAc...) asparagineSequence analysis		1
Glycosylationⁱ	164	N-linked (GlcNAc...) asparagineSequence analysis		1

Post-translational modificationⁱ

Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.1 Publication

Keywords - PTMⁱ

Glycoprotein, Phosphoprotein

Proteomic databases

EPDⁱ	Q15722
PaxDbⁱ	Q15722
PeptideAtlas More...PeptideAtlasⁱ	Q15722
PRIDEⁱ	Q15722
ProteomicsDBⁱ	60717

PTM databases

iPTMnetⁱ	Q15722
PhosphoSitePlusⁱ	Q15722

Expressionⁱ

Tissue specificityⁱ

Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.

Gene expression databases

Bgeeⁱ	ENSG00000213903 Expressed in 152 organ(s), highest expression level in ectocervix
CleanExⁱ	HS_LTB4R
ExpressionAtlasⁱ	Q15722 baseline and differential
Genevisibleⁱ	Q15722 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA003873

HPAⁱ

HPA003873

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	107645, 4 interactors
IntActⁱ	Q15722, 1 interactor
STRINGⁱ	9606.ENSP00000307445

Chemistry databases

BindingDBⁱ

Q15722

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q15722
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000149097
HOGENOMⁱ	HOG000008594
HOVERGENⁱ	HBG104134
InParanoidⁱ	Q15722
KEGG Orthology (KO) More...KOⁱ	K04296
OMAⁱ	FHLLFEA
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0FBQ
PhylomeDBⁱ	Q15722
TreeFamⁱ	TF330976

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR003981 Leukotriene_B4_rcpt IPR003983 Leukotriene_B4_typ-1_rcpt
PANTHERⁱ	PTHR24230:SF51 PTHR24230:SF51, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR01477 LTB1RECEPTOR PR01476 LTBRECEPTOR
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show all Align All

Q15722-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MNTTSSAAPP SLGVEFISLL AIILLSVALA VGLPGNSFVV WSILKRMQKR 
        60         70         80         90        100
SVTALMVLNL ALADLAVLLT APFFLHFLAQ GTWSFGLAGC RLCHYVCGVS 
       110        120        130        140        150
MYASVLLITA MSLDRSLAVA RPFVSQKLRT KAMARRVLAG IWVLSFLLAT 
       160        170        180        190        200
PVLAYRTVVP WKTNMSLCFP RYPSEGHRAF HLIFEAVTGF LLPFLAVVAS 
       210        220        230        240        250
YSDIGRRLQA RRFRRSRRTG RLVVLIILTF AAFWLPYHVV NLAEAGRALA 
       260        270        280        290        300
GQAAGLGLVG KRLSLARNVL IALAFLSSSV NPVLYACAGG GLLRSAGVGF 
       310        320        330        340        350
VAKLLEGTGS EASSTRRGGS LGQTARSGPA ALEPGPSESL TASSPLKLNE 

LN

Length:352

Mass (Da):37,557

Last modified:July 15, 1998 - v2

Checksum:ⁱ5A7BFC0A659AC81C

GO

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

G3V4Q5	G3V4Q5_HUMAN	Leukotriene B4 receptor 1 Leukotriene B4 receptor 1	LTB4R	232	Annotation score:
G3V244	G3V244_HUMAN	Leukotriene B4 receptor 1 Leukotriene B4 receptor 1	LTB4R	102	Annotation score:

Sequence cautionⁱ

The sequence AAB16747 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	246	G → R in CAA67001 (PubMed:8921391).Curated	1
Sequence conflictⁱ	272	A → V in AAC50628 (PubMed:8702478).Curated	1
Sequence conflictⁱ	293	L → V in AAC50628 (PubMed:8702478).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_060679	346	L → F2 PublicationsCorresponds to variant dbSNP:rs17849864Ensembl.		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U41070 mRNA Translation: AAC50628.1 U33448 Genomic DNA Translation: AAB16747.1 Different initiation. D89079 mRNA Translation: BAA20424.1 D89078 mRNA Translation: BAA20423.1 X98356 mRNA Translation: CAA67001.1 AB008193 Genomic DNA Translation: BAB00611.1 AY322535 Genomic DNA Translation: AAP84348.1 BT007267 mRNA Translation: AAP35931.1 BC004545 mRNA Translation: AAH04545.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS9626.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001137391.1, NM_001143919.2 NP_858043.1, NM_181657.3
UniGeneⁱ	Hs.567248

Genome annotation databases

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q15722	Leukotriene B4 receptor 1 (Fragment)		HUMAN		102	UniRef100_Q15722

Protein	Similar proteins		Species	Score	Length	Source
Q15722	Leukotriene B4 receptor 1 (Fragment)		HUMAN		102	UniRef90_Q15722
Uncharacterized protein		CHLSB		353
LTB4R isoform 1		PANTR		352
Uncharacterized protein		PANPA		352
Leukotriene B4 receptor		GORGO		352
+19

Protein	Similar proteins		Species	Score	Length	Source
Q15722	Leukotriene B4 receptor 1 (Fragment)		HUMAN		102	UniRef50_Q15722
Uncharacterized protein		CHLSB		353
LTB4R isoform 1		PANTR		352
Uncharacterized protein		PANPA		352
Leukotriene B4 receptor		GORGO		352
+79

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U41070 mRNA Translation: AAC50628.1 U33448 Genomic DNA Translation: AAB16747.1 Different initiation. D89079 mRNA Translation: BAA20424.1 D89078 mRNA Translation: BAA20423.1 X98356 mRNA Translation: CAA67001.1 AB008193 Genomic DNA Translation: BAB00611.1 AY322535 Genomic DNA Translation: AAP84348.1 BT007267 mRNA Translation: AAP35931.1 BC004545 mRNA Translation: AAH04545.1
CCDSⁱ	CCDS9626.1
RefSeqⁱ	NP_001137391.1, NM_001143919.2 NP_858043.1, NM_181657.3
UniGeneⁱ	Hs.567248

3D structure databases

ProteinModelPortalⁱ	Q15722
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	107645, 4 interactors
IntActⁱ	Q15722, 1 interactor
STRINGⁱ	9606.ENSP00000307445

Chemistry databases

BindingDBⁱ	Q15722
ChEMBLⁱ	CHEMBL3911
GuidetoPHARMACOLOGYⁱ	267
SwissLipidsⁱ	SLP:000001555

Protein family/group databases

TCDBⁱ	9.A.14.13.5 the g-protein-coupled receptor (gpcr) family
GPCRDBⁱ	Search...

PTM databases

iPTMnetⁱ	Q15722
PhosphoSitePlusⁱ	Q15722

Polymorphism and mutation databases

BioMutaⁱ	LTB4R
DMDMⁱ	3041713

Proteomic databases

EPDⁱ	Q15722
PaxDbⁱ	Q15722
PeptideAtlasⁱ	Q15722
PRIDEⁱ	Q15722
ProteomicsDBⁱ	60717

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	1241
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000345363; ENSP00000307445; ENSG00000213903 ENST00000396782; ENSP00000380002; ENSG00000213903 ENST00000396789; ENSP00000380008; ENSG00000213903 ENST00000646659; ENSP00000495785; ENSG00000285456 ENST00000646739; ENSP00000494730; ENSG00000285456 ENST00000647085; ENSP00000495466; ENSG00000285456
GeneIDⁱ	1241
KEGGⁱ	hsa:1241
UCSCⁱ	uc001wos.4 human

Organism-specific databases

CTDⁱ	1241
DisGeNETⁱ	1241
EuPathDBⁱ	HostDB:ENSG00000213903.8
GeneCardsⁱ	LTB4R
H-InvDBⁱ	HIX0172389
HGNCⁱ	HGNC:6713 LTB4R
HPAⁱ	HPA003873
MIMⁱ	601531 gene
neXtProtⁱ	NX_Q15722
OpenTargetsⁱ	ENSG00000213903
PharmGKBⁱ	PA30476
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
GeneTreeⁱ	ENSGT00920000149097
HOGENOMⁱ	HOG000008594
HOVERGENⁱ	HBG104134
InParanoidⁱ	Q15722
KOⁱ	K04296
OMAⁱ	FHLLFEA
OrthoDBⁱ	EOG091G0FBQ
PhylomeDBⁱ	Q15722
TreeFamⁱ	TF330976

Enzyme and pathway databases

Reactomeⁱ	R-HSA-391906 Leukotriene receptors R-HSA-416476 G alpha (q) signalling events
SIGNORⁱ	Q15722

Miscellaneous databases

ChiTaRSⁱ	LTB4R human
GeneWikiⁱ	Leukotriene_B4_receptor
GenomeRNAiⁱ	1241
Protein Ontology More...PROⁱ	PR:Q15722
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000213903 Expressed in 152 organ(s), highest expression level in ectocervix
CleanExⁱ	HS_LTB4R
ExpressionAtlasⁱ	Q15722 baseline and differential
Genevisibleⁱ	Q15722 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR003981 Leukotriene_B4_rcpt IPR003983 Leukotriene_B4_typ-1_rcpt
PANTHERⁱ	PTHR24230:SF51 PTHR24230:SF51, 1 hit
Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR01477 LTB1RECEPTOR PR01476 LTBRECEPTOR
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	LT4R1_HUMAN
Accessionⁱ	Q15722Primary (citable) accession number: Q15722 Secondary accession number(s): Q13305 , Q53XV5, Q92641, Q9BSU5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
	Last sequence update:	July 15, 1998
	Last modified:	November 7, 2018
	This is version 170 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM
7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries

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UniProtKB - Q15722 (LT4R1_HUMAN)

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Leukotriene B4 receptor 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

Chemistry databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ