UniProtKB - Q15637 (SF01_HUMAN)
Protein
Splicing factor 1
Gene
SF1
Organism
Homo sapiens (Human)
Status
Functioni
Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.3 Publications
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 277 – 296 | CCHC-typePROSITE-ProRule annotationAdd BLAST | 20 |
GO - Molecular functioni
- identical protein binding Source: IntAct
- mRNA binding Source: GO_Central
- pre-mRNA branch point binding Source: InterPro
- RNA binding Source: UniProtKB
- transcription corepressor activity Source: ProtInc
- zinc ion binding Source: InterPro
GO - Biological processi
- Leydig cell differentiation Source: Ensembl
- male sex determination Source: Ensembl
- mRNA 3'-splice site recognition Source: HGNC-UCL
- mRNA splicing, via spliceosome Source: Reactome
- negative regulation of smooth muscle cell proliferation Source: Ensembl
- nuclear body organization Source: Ensembl
- regulation of alternative mRNA splicing, via spliceosome Source: GO_Central
- regulation of steroid biosynthetic process Source: Ensembl
- spliceosomal complex assembly Source: UniProtKB
Keywordsi
Molecular function | Repressor, RNA-binding |
Biological process | mRNA processing, mRNA splicing, Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
PathwayCommonsi | Q15637 |
Reactomei | R-HSA-72163, mRNA Splicing - Major Pathway |
SIGNORi | Q15637 |
Protein family/group databases
MoonDBi | Q15637, Predicted |
Names & Taxonomyi
Protein namesi | Recommended name: Splicing factor 1Alternative name(s): Mammalian branch point-binding protein Short name: BBP Short name: mBBP Transcription factor ZFM1 Zinc finger gene in MEN1 locus Zinc finger protein 162 |
Gene namesi | Name:SF1 Synonyms:ZFM1, ZNF162 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000168066.20 |
HGNCi | HGNC:12950, SF1 |
MIMi | 601516, gene |
neXtProti | NX_Q15637 |
Subcellular locationi
Nucleus
Nucleus
- nuclear body Source: Ensembl
- nucleoplasm Source: HPA
- nucleus Source: GO_Central
- spliceosomal complex Source: HGNC-UCL
Other locations
- ribosome Source: UniProtKB
Keywords - Cellular componenti
Nucleus, SpliceosomePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 15 – 17 | KKR → EED: Abolishes interaction with U2AF2. | 3 | |
Mutagenesisi | 16 – 18 | KRK → EDE: Abolishes interaction with U2AF2. 1 Publication | 3 | |
Mutagenesisi | 20 | S → A: Strongly decreases interaction with U2AF2 and spliceosome assembly. 1 Publication | 1 | |
Mutagenesisi | 20 | S → T: Decreases interaction with U2AF2. 1 Publication | 1 | |
Mutagenesisi | 21 | R → A: Decreases interaction with U2AF2 and spliceosome assembly. 1 Publication | 1 | |
Mutagenesisi | 21 | R → K: No effect. 1 Publication | 1 | |
Mutagenesisi | 22 | W → A: Abolishes interaction with U2AF2. 1 Publication | 1 | |
Mutagenesisi | 22 | W → F: No effect. 1 Publication | 1 | |
Mutagenesisi | 151 | N → A: Decreases RNA-binding. 1 Publication | 1 | |
Mutagenesisi | 160 | R → A: Strongly reduces RNA-binding. 1 Publication | 1 | |
Mutagenesisi | 184 | K → A: Abolishes RNA-binding. 1 Publication | 1 | |
Mutagenesisi | 244 | L → A: Decreases RNA-binding. 1 Publication | 1 | |
Mutagenesisi | 247 | L → A: Decreases RNA-binding. 1 Publication | 1 | |
Mutagenesisi | 254 | L → A: Slightly decreases RNA-binding. 1 Publication | 1 | |
Mutagenesisi | 255 | R → A: Slightly decreases RNA-binding. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 7536 |
OpenTargetsi | ENSG00000168066 |
PharmGKBi | PA37533 |
Miscellaneous databases
Pharosi | Q15637, Tbio |
Chemistry databases
DrugBanki | DB11638, Artenimol |
Polymorphism and mutation databases
BioMutai | SF1 |
DMDMi | 38258418 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources1 Publication | |||
ChainiPRO_0000050129 | 2 – 639 | Splicing factor 1Add BLAST | 638 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
Modified residuei | 2 | N-acetylalanineCombined sources1 Publication | 1 | ||
Modified residuei | 14 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 20 | Phosphoserine; by PKG1 Publication | 1 | ||
Modified residuei | 80 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 82 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 87 | PhosphotyrosineCombined sources | 1 | ||
Modified residuei | 89 | PhosphoserineCombined sources | 1 | ||
Isoform 6 (identifier: Q15637-6) | |||||
Modified residuei | 463 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 467 | Omega-N-methylarginineCombined sources | 1 |
Post-translational modificationi
Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463.1 Publication
Keywords - PTMi
Acetylation, Methylation, PhosphoproteinProteomic databases
EPDi | Q15637 |
jPOSTi | Q15637 |
MassIVEi | Q15637 |
MaxQBi | Q15637 |
PaxDbi | Q15637 |
PeptideAtlasi | Q15637 |
PRIDEi | Q15637 |
ProteomicsDBi | 10457 60669 [Q15637-1] 60670 [Q15637-2] 60671 [Q15637-3] 60672 [Q15637-4] 60673 [Q15637-5] 60674 [Q15637-6] |
TopDownProteomicsi | Q15637-4 [Q15637-4] |
PTM databases
GlyGeni | Q15637, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q15637 |
MetOSitei | Q15637 |
PhosphoSitePlusi | Q15637 |
SwissPalmi | Q15637 |
Expressioni
Tissue specificityi
Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart.1 Publication
Gene expression databases
Bgeei | ENSG00000168066, Expressed in testis and 252 other tissues |
ExpressionAtlasi | Q15637, baseline and differential |
Genevisiblei | Q15637, HS |
Organism-specific databases
HPAi | ENSG00000168066, Low tissue specificity |
Interactioni
Subunit structurei
Binds U2AF2.
Interacts with U1 snRNA. Binds EWSR1, FUS and TAF15.
Interacts with RBM17.
7 PublicationsBinary interactionsi
Hide detailsQ15637
Isoform 4 [Q15637-4]
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
BioGRIDi | 113368, 192 interactors |
ComplexPortali | CPX-1074, SF1-U2AF65 splicing factor complex |
CORUMi | Q15637 |
DIPi | DIP-29410N |
ELMi | Q15637 |
IntActi | Q15637, 226 interactors |
MINTi | Q15637 |
STRINGi | 9606.ENSP00000366604 |
Miscellaneous databases
RNActi | Q15637, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
BMRBi | Q15637 |
SMRi | Q15637 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q15637 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 141 – 222 | KHPROSITE-ProRule annotationAdd BLAST | 82 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 15 – 19 | Nuclear localization signalSequence analysis | 5 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 324 – 637 | Pro-richAdd BLAST | 314 |
Sequence similaritiesi
Belongs to the BBP/SF1 family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 277 – 296 | CCHC-typePROSITE-ProRule annotationAdd BLAST | 20 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | KOG0119, Eukaryota |
GeneTreei | ENSGT00940000157258 |
HOGENOMi | CLU_016864_5_0_1 |
InParanoidi | Q15637 |
OMAi | GAAPWHQ |
OrthoDBi | 887669at2759 |
PhylomeDBi | Q15637 |
TreeFami | TF319159 |
Family and domain databases
DisProti | DP01449 |
Gene3Di | 3.30.1370.10, 1 hit |
IDEALi | IID00247 |
InterProi | View protein in InterPro IPR031150, BBP/SF1 IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf IPR032570, SF1-HH IPR001878, Znf_CCHC |
PANTHERi | PTHR11208:SF45, PTHR11208:SF45, 1 hit |
Pfami | View protein in Pfam PF00013, KH_1, 1 hit PF16275, SF1-HH, 1 hit PF00098, zf-CCHC, 1 hit |
SMARTi | View protein in SMART SM00322, KH, 1 hit SM00343, ZnF_C2HC, 1 hit |
SUPFAMi | SSF54791, SSF54791, 1 hit |
PROSITEi | View protein in PROSITE PS50084, KH_TYPE_1, 1 hit PS50158, ZF_CCHC, 1 hit |
s (7+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 7 produced by isoformsialternative splicing. AlignAdd to basketNote: Additional isoforms seem to exist.
This entry has 7 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q15637-1) [UniParc]FASTAAdd to basket
Also known as: SF1-HL1
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MATGANATPL DFPSKKRKRS RWNQDTMEQK TVIPGMPTVI PPGLTREQER
60 70 80 90 100
AYIVQLQIED LTRKLRTGDL GIPPNPEDRS PSPEPIYNSE GKRLNTREFR
110 120 130 140 150
TRKKLEEERH NLITEMVALN PDFKPPADYK PPATRVSDKV MIPQDEYPEI
160 170 180 190 200
NFVGLLIGPR GNTLKNIEKE CNAKIMIRGK GSVKEGKVGR KDGQMLPGED
210 220 230 240 250
EPLHALVTAN TMENVKKAVE QIRNILKQGI ETPEDQNDLR KMQLRELARL
260 270 280 290 300
NGTLREDDNR ILRPWQSSET RSITNTTVCT KCGGAGHIAS DCKFQRPGDP
310 320 330 340 350
QSAQDKARMD KEYLSLMAEL GEAPVPASVG STSGPATTPL ASAPRPAAPA
360 370 380 390 400
NNPPPPSLMS TTQSRPPWMN SGPSESRPYH GMHGGGPGGP GGGPHSFPHP
410 420 430 440 450
LPSLTGGHGG HPMQHNPNGP PPPWMQPPPP PMNQGPHPPG HHGPPPMDQY
460 470 480 490 500
LGSTPVGSGV YRLHQGKGMM PPPPMGMMPP PPPPPSGQPP PPPSGPLPPW
510 520 530 540 550
QQQQQQPPPP PPPSSSMASS TPLPWQQNTT TTTTSAGTGS IPPWQQQQAA
560 570 580 590 600
AAASPGAPQM QGNPTMVPLP PGVQPPLPPG APPPPPPPPP GSAGMMYAPP
610 620 630
PPPPPPMDPS NFVTMMGMGV AGMPPFGMPP APPPPPPQN
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketC9J792 | C9J792_HUMAN | Splicing factor 1 | SF1 | 62 | Annotation score: | ||
H7C0N4 | H7C0N4_HUMAN | Splicing factor 1 | SF1 | 180 | Annotation score: | ||
H7C561 | H7C561_HUMAN | Splicing factor 1 | SF1 | 291 | Annotation score: | ||
H7BZT1 | H7BZT1_HUMAN | Splicing factor 1 | SF1 | 200 | Annotation score: | ||
F8WEV5 | F8WEV5_HUMAN | Splicing factor 1 | SF1 | 110 | Annotation score: | ||
F8WEG7 | F8WEG7_HUMAN | Splicing factor 1 | SF1 | 51 | Annotation score: |
Sequence cautioni
The sequence AAH00773 differs from that shown. Reason: Erroneous initiation.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 269 | E → G in BAA05116 (PubMed:7912130).Curated | 1 | |
Sequence conflicti | 269 | E → G in BAA05117 (PubMed:7912130).Curated | 1 | |
Sequence conflicti | 348 | A → R in AAB03514 (PubMed:9192847).Curated | 1 | |
Sequence conflicti | 348 | A → R in AAB04033 (PubMed:9192847).Curated | 1 | |
Sequence conflicti | 377 | R → W in BAA05116 (PubMed:7912130).Curated | 1 | |
Sequence conflicti | 377 | R → W in BAA05117 (PubMed:7912130).Curated | 1 | |
Sequence conflicti | 570 | P → L in BAH11587 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 591 | G → V in AAB04033 (PubMed:9192847).Curated | 1 | |
Sequence conflicti | 623 | M → I in AAB04033 (PubMed:9192847).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_017196 | 357 | S → T1 Publication | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_045274 | 1 – 26 | Missing in isoform 7. 1 PublicationAdd BLAST | 26 | |
Alternative sequenceiVSP_008833 | 10 | L → LGKLGPPGLPPLPGPKGGFE PGPPPAPGPGAGLLAPGPPP PPPVGSMGALTAAFPFAALP PPPPPPPPPPPQQPPPPPPP PSPGASYPPPQPPPPPPLYQ RVSPPQPPPPQPPRKDQQPG PAGGGG in isoform 5. 1 Publication | 1 | |
Alternative sequenceiVSP_008834 | 448 – 548 | DQYLG…WQQQQ → GKSVPGKYACGLWGLSPASR KRYDAATTYGHDA in isoform 6. 1 PublicationAdd BLAST | 101 | |
Alternative sequenceiVSP_008835 | 528 – 548 | NTTTT…WQQQQ → RSLPAAAMARAMRVRTFRAH W in isoform 4 and isoform 5. 2 PublicationsAdd BLAST | 21 | |
Alternative sequenceiVSP_008836 | 549 – 639 | Missing in isoform 4 and isoform 5. 2 PublicationsAdd BLAST | 91 | |
Alternative sequenceiVSP_008837 | 555 – 639 | PGAPQ…PPPQN → QWAAPTPSLWSSSPMATTAA AASATPSAQQQYGFQYPLAM AAKIPPRGGDGPSHESEDFP RPLVTLPGRQPQQRPWWTGW FGKAA in isoform 6. 1 PublicationAdd BLAST | 85 | |
Alternative sequenceiVSP_008838 | 587 – 639 | PPPPG…PPPQN → RSIECLLCLLSLLTQLPLPL PKPGRQDPSPRRRWPEP in isoform 3. 1 PublicationAdd BLAST | 53 | |
Alternative sequenceiVSP_008839 | 597 – 639 | YAPPP…PPPQN → IPPRGGDGPSHESEDFPRPL VTLPGRQPQQRPWWTGWFGK AA in isoform 2. 1 PublicationAdd BLAST | 43 |
Sequence databases
Genome annotation databases
Ensembli | ENST00000227503; ENSP00000227503; ENSG00000168066 [Q15637-4] ENST00000334944; ENSP00000334414; ENSG00000168066 [Q15637-2] ENST00000377387; ENSP00000366604; ENSG00000168066 [Q15637-5] ENST00000377390; ENSP00000366607; ENSG00000168066 [Q15637-1] ENST00000377394; ENSP00000366611; ENSG00000168066 [Q15637-6] ENST00000433274; ENSP00000396793; ENSG00000168066 [Q15637-7] |
GeneIDi | 7536 |
KEGGi | hsa:7536 |
UCSCi | uc001oaz.3, human [Q15637-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1K1G | NMR | - | A | 133-260 | [»] | |
1O0P | NMR | - | B | 13-25 | [»] | |
1OPI | NMR | - | B | 13-25 | [»] | |
2M09 | NMR | - | A | 27-145 | [»] | |
2M0G | NMR | - | A | 1-145 | [»] | |
4FXW | X-ray | 2.29 | B/D | 14-132 | [»] | |
4FXX | X-ray | 2.48 | A/B/C/D | 26-132 | [»] | |
BMRBi | Q15637 | |||||
SMRi | Q15637 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 113368, 192 interactors |
ComplexPortali | CPX-1074, SF1-U2AF65 splicing factor complex |
CORUMi | Q15637 |
DIPi | DIP-29410N |
ELMi | Q15637 |
IntActi | Q15637, 226 interactors |
MINTi | Q15637 |
STRINGi | 9606.ENSP00000366604 |
Chemistry databases
DrugBanki | DB11638, Artenimol |
Protein family/group databases
MoonDBi | Q15637, Predicted |
PTM databases
GlyGeni | Q15637, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q15637 |
MetOSitei | Q15637 |
PhosphoSitePlusi | Q15637 |
SwissPalmi | Q15637 |
Polymorphism and mutation databases
BioMutai | SF1 |
DMDMi | 38258418 |
Proteomic databases
EPDi | Q15637 |
jPOSTi | Q15637 |
MassIVEi | Q15637 |
MaxQBi | Q15637 |
PaxDbi | Q15637 |
PeptideAtlasi | Q15637 |
PRIDEi | Q15637 |
ProteomicsDBi | 10457 60669 [Q15637-1] 60670 [Q15637-2] 60671 [Q15637-3] 60672 [Q15637-4] 60673 [Q15637-5] 60674 [Q15637-6] |
TopDownProteomicsi | Q15637-4 [Q15637-4] |
Protocols and materials databases
Antibodypediai | 15586, 399 antibodies |
DNASUi | 7536 |
Genome annotation databases
Ensembli | ENST00000227503; ENSP00000227503; ENSG00000168066 [Q15637-4] ENST00000334944; ENSP00000334414; ENSG00000168066 [Q15637-2] ENST00000377387; ENSP00000366604; ENSG00000168066 [Q15637-5] ENST00000377390; ENSP00000366607; ENSG00000168066 [Q15637-1] ENST00000377394; ENSP00000366611; ENSG00000168066 [Q15637-6] ENST00000433274; ENSP00000396793; ENSG00000168066 [Q15637-7] |
GeneIDi | 7536 |
KEGGi | hsa:7536 |
UCSCi | uc001oaz.3, human [Q15637-1] |
Organism-specific databases
CTDi | 7536 |
DisGeNETi | 7536 |
EuPathDBi | HostDB:ENSG00000168066.20 |
GeneCardsi | SF1 |
HGNCi | HGNC:12950, SF1 |
HPAi | ENSG00000168066, Low tissue specificity |
MIMi | 601516, gene |
neXtProti | NX_Q15637 |
OpenTargetsi | ENSG00000168066 |
PharmGKBi | PA37533 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0119, Eukaryota |
GeneTreei | ENSGT00940000157258 |
HOGENOMi | CLU_016864_5_0_1 |
InParanoidi | Q15637 |
OMAi | GAAPWHQ |
OrthoDBi | 887669at2759 |
PhylomeDBi | Q15637 |
TreeFami | TF319159 |
Enzyme and pathway databases
PathwayCommonsi | Q15637 |
Reactomei | R-HSA-72163, mRNA Splicing - Major Pathway |
SIGNORi | Q15637 |
Miscellaneous databases
BioGRID-ORCSi | 7536, 778 hits in 856 CRISPR screens |
ChiTaRSi | SF1, human |
EvolutionaryTracei | Q15637 |
GeneWikii | SF1_(gene) |
GenomeRNAii | 7536 |
Pharosi | Q15637, Tbio |
PROi | PR:Q15637 |
RNActi | Q15637, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000168066, Expressed in testis and 252 other tissues |
ExpressionAtlasi | Q15637, baseline and differential |
Genevisiblei | Q15637, HS |
Family and domain databases
DisProti | DP01449 |
Gene3Di | 3.30.1370.10, 1 hit |
IDEALi | IID00247 |
InterProi | View protein in InterPro IPR031150, BBP/SF1 IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf IPR032570, SF1-HH IPR001878, Znf_CCHC |
PANTHERi | PTHR11208:SF45, PTHR11208:SF45, 1 hit |
Pfami | View protein in Pfam PF00013, KH_1, 1 hit PF16275, SF1-HH, 1 hit PF00098, zf-CCHC, 1 hit |
SMARTi | View protein in SMART SM00322, KH, 1 hit SM00343, ZnF_C2HC, 1 hit |
SUPFAMi | SSF54791, SSF54791, 1 hit |
PROSITEi | View protein in PROSITE PS50084, KH_TYPE_1, 1 hit PS50158, ZF_CCHC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SF01_HUMAN | |
Accessioni | Q15637Primary (citable) accession number: Q15637 Secondary accession number(s): B7Z1Q1 Q9UEI0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 7, 2003 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 211 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations