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1 to 24 of 24  Show
  1. 1
    "Cloning and sequencing of cDNAs encoding the human sperm protein, Sp17."
    Lea I.A., Richardson R.T., Widgren E.E., O'Rand M.G.
    Biochim. Biophys. Acta 1307:263-266(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Tissue: Testis.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "Genomic organization of an intron-containing sperm protein 17 gene (Sp17-1) and an intronless pseudogene (Sp17-2) in humans: a new model."
    Buchli R., De Jong A., Robbins D.L.
    Biochim. Biophys. Acta 1578:29-42(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Tissue: Testis.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 1 other entries.

  3. 3
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Testis.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12931 other entries.

  4. 4
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3717 other entries.

  5. 5
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50469 other entries.

  6. 6
    "A yeast two-hybrid system using Sp17 identified ropporin as a novel cancer-testis antigen in hematologic malignancies."
    Li Z., Li W., Meklat F., Wang Z., Zhang J., Zhang Y., Lim S.H.
    Int. J. Cancer 121:1507-1511(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: POSSIBLE INTERACTION WITH ROPN1.
    Category: Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  7. 7
    "Characterization of sperm protein 17 in human somatic and neoplastic tissue."
    De Jong A., Buchli R., Robbins D.
    Cancer Lett. 186:201-209(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: Sp17 has different expression patterns in cancer cell lines as compared to normal non-testes tissues and a potential pathogenic role in diseased cellsImported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  8. 8
    "Developmental considerations of sperm protein 17 gene expression in rheumatoid arthritis synoviocytes."
    Takeoka Y., Kenny T.P., Yago H., Naiki M., Gershwin M.E., Robbins D.L.
    Dev. Immunol. 9:97-102(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: expression of Sp17 a thought to be gamete-specific protein in the synoviocytes of 8/8 female rheumatoid arthritis patientsImported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  9. 9
    "Identification of a sperm protein 17 CTL epitope restricted by HLA-A1."
    Chiriva-Internati M., Wang Z., Pochopien S., Salati E., Lim S.H.
    Int. J. Cancer 107:863-865(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: identification of a nonapeptide sequence within the Sp17 protein that is predicted to have a high binding affinity for HLA-A1 moleculesImported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  10. 10
    "Expression of sperm protein 17 (Sp17) in ovarian cancer."
    Straughn J.M. Jr., Shaw D.R., Guerrero A., Bhoola S.M., Racelis A., Wang Z., Chiriva-Internati M., Grizzle W.E., Alvarez R.D., Lim S.H., Strong T.V.
    Int. J. Cancer 108:805-811(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Expression, Sequences.
    Annotation: Sp17 is expressed in the cell nucleus of ovarian neoplasmsImported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  11. 11
    "Sp17 gene expression in myeloma cells is regulated by promoter methylation."
    Wang Z., Zhang Y., Ramsahoye B., Bowen D., Lim S.H.
    Br. J. Cancer 91:1597-1603(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Sp17 gene expression in myeloma cells is regulated by promoter methylationImported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  12. 12
    "Clinical significance of sperm protein 17 expression and immunogenicity in esophageal cancer."
    Gupta G., Sharma R., Chattopadhyay T.K., Gupta S.D., Ralhan R.
    Int. J. Cancer 120:1739-1747(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Overexpression of sperm protein 17 is associated with esophageal cancerImported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  13. 13
    "Sperm protein 17 is a suitable target for adoptive T-cell-based immunotherapy in human ovarian cancer."
    Chiriva-Internati M., Weidanz J.A., Yu Y., Frezza E.E., Jenkins M.R., Kennedy R.C., Cobos E., Kast W.M.
    J. Immunother. 31:693-703(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: in vitro cultured monoclonal cytotoxic T lymphocytes (derived either from advanced OC patients or from healthy donors) specific for sperm protein 17 can eradicate human metastatic OC cells.Imported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  14. 14
    "Sperm protein 17 is expressed in the sperm fibrous sheath."
    Chiriva-Internati M., Gagliano N., Donetti E., Costa F., Grizzi F., Franceschini B., Albani E., Levi-Setti P.E., Gioia M., Jenkins M., Cobos E., Kast W.M.
    J Transl Med 7:61-61(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Sequences.
    Annotation: Results suggest a possible role of Sp17 in regulating sperm maturation capacitation acrosomal reaction and interactions with the oocyte zona pellucida during the fertilization process.Imported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  15. 15
    "Sperm protein 17 is a novel marker for predicting cisplatin response in esophageal squamous cancer cell lines."
    Kausar T., Ahsan A., Hasan M.R., Lin L., Beer D.G., Ralhan R.
    Int. J. Cancer 126:1494-1503(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Data show that cisplatin induced decrease in Sp17 levels was due to transcriptional inhibition and cisplatin-resistant cell lines did not show this decrease in Sp17 levels in response to cisplatin treatment.Imported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  16. 16
    "Overexpression of human sperm protein 17 increases migration and decreases the chemosensitivity of human epithelial ovarian cancer cells."
    Li F.Q., Han Y.L., Liu Q., Wu B., Huang W.B., Zeng S.Y.
    BMC Cancer 9:323-323(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: HSp17 plays a role in metastatic disease and resistance of epithelial ovarian carcinoma to chemotherapyImported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  17. 17
    "Sperm protein 17 is highly expressed in endometrial and cervical cancers."
    Li F.Q., Liu Q., Han Y.L., Wu B., Yin H.L.
    BMC Cancer 10:429-429(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Sperm protein 17 is highly expressed in endometrial and cervical cancers.Imported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  18. 18
    "Limited SP17 expression within tumors diminishes its therapeutic potential."
    Gjerstorff M.F., Ditzel H.J.
    Tissue Antigens 80:523-527(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: SP17 was expressed in many cancer types with an overall frequency of 12%. SP17 was most frequently expressed in a different set of cancer types than MAGE-A and GAGE antigens and rarely overlapped with these proteins.Imported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

  19. 19
    "Sperm protein 17, MAGE-C1 and NY-ESO-1 in hepatocellular carcinoma: expression frequency and their correlation with clinical parameters."
    Xia Q.Y., Liu S., Li F.Q., Huang W.B., Shi L.N., Zhou X.J.
    Int J Clin Exp Pathol 6:1610-1616(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Sp17 is highly expressed in hepatocellular carcinoma cellsImported.
    Source: GeneRIF:53340.

    This publication is mapped to 5 other entries.

  20. 20
    "Analysis of GAGE, NY-ESO-1 and SP17 cancer/testis antigen expression in early stage non-small cell lung carcinoma."
    Gjerstorff M.F., Pohl M., Olsen K.E., Ditzel H.J.
    BMC Cancer 13:466-466(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: NY-ESO-1 and SP17 was not significantly associated with a specific histotype but high-level GAGE expression was more frequent in squamous cell carcinoma. GAGE expression was demonstrated to be significantly higher in stage II-IIIa than stage I NSCLC.Imported.
    Source: GeneRIF:53340.

    This publication is mapped to 4 other entries.

  21. 21
    Category: Interaction.
    Source: IntAct:Q15506.

    This publication is mapped to 4115 other entries.

  22. 22
    "Sperm protein 17 and AKAP-associated sperm protein cancer/testis antigens are expressed in ciliated hepatic foregut cysts."
    Grizzi F., Franceschini B., Di Biccari S., Musardo S., Pedretti E., Chiriva-Internati M., Osipov V., Fernandez-Acenero M.J.
    Histopathology 67:398-403(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Annotation: Sp17 and ASP cancer/testis antigens were found in ciliated cells of four ciliated hepatic foregut cysts (CHFCs). Further characterization of Sp17 and ASP in patients with CHFCs may provide significant clues for understanding the molecular mechanisms underlying their predisposition to develop squamous cell carcinomas.Imported.
    Source: GeneRIF:53340.

    This publication is mapped to 4 other entries.

  23. 23
    "Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets."
    Mirandola L., Figueroa J.A., Phan T.T., Grizzi F., Kim M., Rahman R.L., Jenkins M.R., Cobos E., Jumper C., Alalawi R., Chiriva-Internati M.
    Oncotarget 6:2812-2826(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: SP17/AKAP4/PTTG1 are expressed in both human NSCLC cell lines and primary tumors and can elicit an immunogenic response in lung cancer patients.Imported.
    Source: GeneRIF:53340.

    This publication is mapped to 9 other entries.

  24. 24
    "Umbilical cord blood-derived dendritic cells infected by adenovirus for SP17 expression induce antigen-specific cytotoxic T cells against NSCLC cells."
    Liu Y., Tian X., Jiang S., Ren X., Liu F., Yang J., Chen Y., Jiang Y.
    Cell. Immunol. 298:18-24(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: dendritic cells from human umbilical cord blood modulated for SP17 expression induced antigen-specific anti-tumor immunity against SP17(+) non-small cell lung cancer.Imported.
    Source: GeneRIF:53340.

    This publication is mapped to 2 other entries.

1 to 24 of 24  Show
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