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UniProtKB - Q15404 (RSU1_HUMAN)

Entry version 169 (11 Dec 2019)
Sequence version 3 (23 Jan 2007)
Previous versions | rss
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Protein

Ras suppressor protein 1

Gene

RSU1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-446388 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q15404

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ras suppressor protein 1
Short name:
RSP-1
Short name:
Rsu-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RSU1
Synonyms:RSP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000148484.17

Human Gene Nomenclature Database

More...HGNCi		HGNC:10464 RSU1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		179555 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q15404

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		6251

Open Targets

More...OpenTargetsi		ENSG00000148484

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA34876

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q15404 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		RSU1

Domain mapping of disease mutations (DMDM)

More...DMDMi		2498866

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000974992 – 277Ras suppressor protein 1Add BLAST276

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q15404

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q15404

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q15404

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q15404

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q15404

PeptideAtlas

More...PeptideAtlasi		Q15404

PRoteomics IDEntifications database

More...PRIDEi		Q15404

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		60570 [Q15404-1]
60571 [Q15404-2]

2D gel databases

USC-OGP 2-DE database

More...OGPi		Q15404

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q15404

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q15404

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000148484 Expressed in 235 organ(s), highest expression level in popliteal artery

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q15404 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA025927

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
P480595EBI-1057132,EBI-306928

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		112164, 33 interactors

Protein interaction database and analysis system

More...IntActi		Q15404, 12 interactors

Molecular INTeraction database

More...MINTi		Q15404

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000367154

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q15404 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati41 – 63LRR 1Add BLAST23
Repeati64 – 85LRR 2Add BLAST22
Repeati87 – 109LRR 3Add BLAST23
Repeati110 – 133LRR 4Add BLAST24
Repeati135 – 156LRR 5Add BLAST22
Repeati158 – 179LRR 6Add BLAST22
Repeati181 – 202LRR 7Add BLAST22

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0617 Eukaryota
COG4886 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158676

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000116557

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q15404

Identification of Orthologs from Complete Genome Data

More...OMAi		IRELHIQ

Database of Orthologous Groups

More...OrthoDBi		1382533at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q15404

TreeFam database of animal gene trees

More...TreeFami		TF314790

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.80.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001611 Leu-rich_rpt
IPR025875 Leu-rich_rpt_4
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12799 LRR_4, 1 hit
PF13855 LRR_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00369 LRR_TYP, 7 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51450 LRR, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q15404-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSKSLKKLVE ESREKNQPEV DMSDRGISNM LDVNGLFTLS HITQLVLSHN 
        60         70         80         90        100
KLTMVPPNIA ELKNLEVLNF FNNQIEELPT QISSLQKLKH LNLGMNRLNT 
       110        120        130        140        150
LPRGFGSLPA LEVLDLTYNN LSENSLPGNF FYLTTLRALY LSDNDFEILP 
       160        170        180        190        200
PDIGKLTKLQ ILSLRDNDLI SLPKEIGELT QLKELHIQGN RLTVLPPELG 
       210        220        230        240        250
NLDLTGQKQV FKAENNPWVT PIADQFQLGV SHVFEYIRSE TYKYLYGRHM 
       260        270 
QANPEPPKKN NDKSKKISRK PLAAKNR
Length:277
Mass (Da):31,540
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6EDB2E033F417468
GO
Isoform 2 (identifier: Q15404-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-53: Missing.

Show »
Length:224
Mass (Da):25,545
Checksum:i1ACDF598D19296E1
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0438311 – 53Missing in isoform 2. 1 PublicationAdd BLAST53

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
L12535 mRNA Translation: AAA60292.1
AK292911 mRNA Translation: BAF85600.1
AK312520 mRNA Translation: BAG35419.1
CR536521 mRNA Translation: CAG38758.1
CR541840 mRNA Translation: CAG46639.1
EF445013 Genomic DNA Translation: ACA06048.1
EF445013 Genomic DNA Translation: ACA06049.1
EF445013 Genomic DNA Translation: ACA06050.1
AC073367 Genomic DNA No translation available.
AL365215 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86222.1
CH471072 Genomic DNA Translation: EAW86223.1
CH471072 Genomic DNA Translation: EAW86224.1
BC005993 mRNA Translation: AAH05993.1
BC008691 mRNA Translation: AAH08691.1
BC015644 mRNA Translation: AAH15644.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS31157.1 [Q15404-2]
CCDS7112.1 [Q15404-1]

Protein sequence database of the Protein Information Resource

More...PIRi		I60122

NCBI Reference Sequences

More...RefSeqi		NP_036557.1, NM_012425.3 [Q15404-1]
NP_689937.2, NM_152724.2 [Q15404-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000345264; ENSP00000339521; ENSG00000148484 [Q15404-1]
ENST00000377921; ENSP00000367154; ENSG00000148484 [Q15404-1]
ENST00000602389; ENSP00000473588; ENSG00000148484 [Q15404-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		6251

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:6251

UCSC genome browser

More...UCSCi		uc001iok.4 human [Q15404-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L12535 mRNA Translation: AAA60292.1
AK292911 mRNA Translation: BAF85600.1
AK312520 mRNA Translation: BAG35419.1
CR536521 mRNA Translation: CAG38758.1
CR541840 mRNA Translation: CAG46639.1
EF445013 Genomic DNA Translation: ACA06048.1
EF445013 Genomic DNA Translation: ACA06049.1
EF445013 Genomic DNA Translation: ACA06050.1
AC073367 Genomic DNA No translation available.
AL365215 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86222.1
CH471072 Genomic DNA Translation: EAW86223.1
CH471072 Genomic DNA Translation: EAW86224.1
BC005993 mRNA Translation: AAH05993.1
BC008691 mRNA Translation: AAH08691.1
BC015644 mRNA Translation: AAH15644.1
CCDSiCCDS31157.1 [Q15404-2]
CCDS7112.1 [Q15404-1]
PIRiI60122
RefSeqiNP_036557.1, NM_012425.3 [Q15404-1]
NP_689937.2, NM_152724.2 [Q15404-2]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGridi112164, 33 interactors
IntActiQ15404, 12 interactors
MINTiQ15404
STRINGi9606.ENSP00000367154

PTM databases

iPTMnetiQ15404
PhosphoSitePlusiQ15404

Polymorphism and mutation databases

BioMutaiRSU1
DMDMi2498866

2D gel databases

OGPiQ15404

Proteomic databases

EPDiQ15404
jPOSTiQ15404
MassIVEiQ15404
MaxQBiQ15404
PaxDbiQ15404
PeptideAtlasiQ15404
PRIDEiQ15404
ProteomicsDBi60570 [Q15404-1]
60571 [Q15404-2]

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		6251

Genome annotation databases

EnsembliENST00000345264; ENSP00000339521; ENSG00000148484 [Q15404-1]
ENST00000377921; ENSP00000367154; ENSG00000148484 [Q15404-1]
ENST00000602389; ENSP00000473588; ENSG00000148484 [Q15404-2]
GeneIDi6251
KEGGihsa:6251
UCSCiuc001iok.4 human [Q15404-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		6251
DisGeNETi6251
EuPathDBiHostDB:ENSG00000148484.17

GeneCards: human genes, protein and diseases

More...GeneCardsi		RSU1
HGNCiHGNC:10464 RSU1
HPAiHPA025927
MIMi179555 gene
neXtProtiNX_Q15404
OpenTargetsiENSG00000148484
PharmGKBiPA34876

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0617 Eukaryota
COG4886 LUCA
GeneTreeiENSGT00940000158676
HOGENOMiHOG000116557
InParanoidiQ15404
OMAiIRELHIQ
OrthoDBi1382533at2759
PhylomeDBiQ15404
TreeFamiTF314790

Enzyme and pathway databases

ReactomeiR-HSA-446388 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
SignaLinkiQ15404

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		RSU1 human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		RSU1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		6251
PharosiQ15404 Tbio

Protein Ontology

More...PROi		PR:Q15404
RNActiQ15404 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000148484 Expressed in 235 organ(s), highest expression level in popliteal artery
GenevisibleiQ15404 HS

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR025875 Leu-rich_rpt_4
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
PfamiView protein in Pfam
PF12799 LRR_4, 1 hit
PF13855 LRR_8, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 7 hits
PROSITEiView protein in PROSITE
PS51450 LRR, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRSU1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q15404
Secondary accession number(s): A8KA46, D3DRU3, Q6FI17
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 23, 2007
Last modified: December 11, 2019
This is version 169 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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