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Entry version 190 (12 Aug 2020)
Sequence version 1 (01 Nov 1996)
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Protein

Mitochondrial import receptor subunit TOM20 homolog

Gene

TOMM20

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q15388

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-1268020, Mitochondrial protein import
R-HSA-5205685, Pink/Parkin Mediated Mitophagy
R-HSA-5689880, Ub-specific processing proteases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mitochondrial import receptor subunit TOM20 homolog
Alternative name(s):
Mitochondrial 20 kDa outer membrane protein
Outer mitochondrial membrane receptor Tom20
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TOMM20
Synonyms:KIAA0016
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000173726.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20947, TOMM20

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
601848, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q15388

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 6Mitochondrial intermembraneSequence analysis6
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei7 – 24HelicalSequence analysisAdd BLAST18
Topological domaini25 – 145CytoplasmicSequence analysisAdd BLAST121

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi56K → R: Defects in mitophagy; when associated with R-61 and R-68. 1 Publication1
Mutagenesisi61K → R: Defects in mitophagy; when associated with R-56 and R-68. 1 Publication1
Mutagenesisi68K → R: Defects in mitophagy; when associated with R-56 and R-61. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
9804

Open Targets

More...
OpenTargetsi
ENSG00000173726

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134964372

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q15388, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TOMM20

Domain mapping of disease mutations (DMDM)

More...
DMDMi
2498697

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000515381 – 145Mitochondrial import receptor subunit TOM20 homologAdd BLAST145

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki35Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Cross-linki56Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)2 Publications
Cross-linki61Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)2 Publications
Cross-linki68Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei135PhosphoserineCombined sources1
Modified residuei138PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.2 Publications

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q15388

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q15388

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q15388

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q15388

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q15388

PeptideAtlas

More...
PeptideAtlasi
Q15388

PRoteomics IDEntifications database

More...
PRIDEi
Q15388

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
60558

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q15388

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q15388

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q15388

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000173726, Expressed in forebrain and 252 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q15388, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q15388, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000173726, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70).

Interacts with TOM22.

Interacts with APEX1.

2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
115144, 171 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q15388

Database of interacting proteins

More...
DIPi
DIP-46735N

Protein interaction database and analysis system

More...
IntActi
Q15388, 153 interactors

Molecular INTeraction database

More...
MINTi
Q15388

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000355566

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q15388, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q15388

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Tom20 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4056, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011698

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_100000_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q15388

KEGG Orthology (KO)

More...
KOi
K17770

Identification of Orthologs from Complete Genome Data

More...
OMAi
KDEGFPT

Database of Orthologous Groups

More...
OrthoDBi
1316067at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q15388

TreeFam database of animal gene trees

More...
TreeFami
TF106200

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.960.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002056, MAS20
IPR022422, MAS20_rcpt_metazoan
IPR023392, Tom20_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR12430, PTHR12430, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02064, MAS20, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037707, MAS20_rcpt, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01989, EUOM20RECPTR
PR00351, OM20RECEPTOR

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47157, SSF47157, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00985, 3a0801s04tom, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q15388-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVGRNSAIAA GVCGALFIGY CIYFDRKRRS DPNFKNRLRE RRKKQKLAKE
60 70 80 90 100
RAGLSKLPDL KDAEAVQKFF LEEIQLGEEL LAQGEYEKGV DHLTNAIAVC
110 120 130 140
GQPQQLLQVL QQTLPPPVFQ MLLTKLPTIS QRIVSAQSLA EDDVE
Length:145
Mass (Da):16,298
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5153BD25AC5D9B3A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti145E → D in CAG32999 (Ref. 6) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052366117P → L. Corresponds to variant dbSNP:rs16991984Ensembl.1
Natural variantiVAR_052367134V → L. Corresponds to variant dbSNP:rs1049510Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF126962 AF126961 Genomic DNA Translation: AAF13354.1
D13641 mRNA Translation: BAA02804.1
AK289810 mRNA Translation: BAF82499.1
CR456718 mRNA Translation: CAG32999.1
AL732292 Genomic DNA No translation available.
CH471098 Genomic DNA Translation: EAW70003.1
BC000882 mRNA Translation: AAH00882.1
BC066335 mRNA Translation: AAH66335.1
BC071994 mRNA Translation: AAH71994.1
BC100286 mRNA Translation: AAI00287.1
BC107851 mRNA Translation: AAI07852.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1603.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S68215

NCBI Reference Sequences

More...
RefSeqi
NP_055580.1, NM_014765.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000366607; ENSP00000355566; ENSG00000173726

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9804

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9804

UCSC genome browser

More...
UCSCi
uc001hwl.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF126962 AF126961 Genomic DNA Translation: AAF13354.1
D13641 mRNA Translation: BAA02804.1
AK289810 mRNA Translation: BAF82499.1
CR456718 mRNA Translation: CAG32999.1
AL732292 Genomic DNA No translation available.
CH471098 Genomic DNA Translation: EAW70003.1
BC000882 mRNA Translation: AAH00882.1
BC066335 mRNA Translation: AAH66335.1
BC071994 mRNA Translation: AAH71994.1
BC100286 mRNA Translation: AAI00287.1
BC107851 mRNA Translation: AAI07852.1
CCDSiCCDS1603.1
PIRiS68215
RefSeqiNP_055580.1, NM_014765.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4APOX-ray1.90D/E140-145[»]
SMRiQ15388
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi115144, 171 interactors
CORUMiQ15388
DIPiDIP-46735N
IntActiQ15388, 153 interactors
MINTiQ15388
STRINGi9606.ENSP00000355566

PTM databases

iPTMnetiQ15388
PhosphoSitePlusiQ15388

Polymorphism and mutation databases

BioMutaiTOMM20
DMDMi2498697

Proteomic databases

EPDiQ15388
jPOSTiQ15388
MassIVEiQ15388
MaxQBiQ15388
PaxDbiQ15388
PeptideAtlasiQ15388
PRIDEiQ15388
ProteomicsDBi60558
TopDownProteomicsiQ15388

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2619, 209 antibodies

The DNASU plasmid repository

More...
DNASUi
9804

Genome annotation databases

EnsembliENST00000366607; ENSP00000355566; ENSG00000173726
GeneIDi9804
KEGGihsa:9804
UCSCiuc001hwl.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9804
DisGeNETi9804
EuPathDBiHostDB:ENSG00000173726.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TOMM20
HGNCiHGNC:20947, TOMM20
HPAiENSG00000173726, Low tissue specificity
MIMi601848, gene
neXtProtiNX_Q15388
OpenTargetsiENSG00000173726
PharmGKBiPA134964372

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4056, Eukaryota
GeneTreeiENSGT00390000011698
HOGENOMiCLU_100000_0_0_1
InParanoidiQ15388
KOiK17770
OMAiKDEGFPT
OrthoDBi1316067at2759
PhylomeDBiQ15388
TreeFamiTF106200

Enzyme and pathway databases

PathwayCommonsiQ15388
ReactomeiR-HSA-1268020, Mitochondrial protein import
R-HSA-5205685, Pink/Parkin Mediated Mitophagy
R-HSA-5689880, Ub-specific processing proteases

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
9804, 570 hits in 855 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TOMM20, human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TOMM20

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9804
PharosiQ15388, Tbio

Protein Ontology

More...
PROi
PR:Q15388
RNActiQ15388, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000173726, Expressed in forebrain and 252 other tissues
ExpressionAtlasiQ15388, baseline and differential
GenevisibleiQ15388, HS

Family and domain databases

Gene3Di1.20.960.10, 1 hit
InterProiView protein in InterPro
IPR002056, MAS20
IPR022422, MAS20_rcpt_metazoan
IPR023392, Tom20_dom_sf
PANTHERiPTHR12430, PTHR12430, 1 hit
PfamiView protein in Pfam
PF02064, MAS20, 1 hit
PIRSFiPIRSF037707, MAS20_rcpt, 1 hit
PRINTSiPR01989, EUOM20RECPTR
PR00351, OM20RECEPTOR
SUPFAMiSSF47157, SSF47157, 1 hit
TIGRFAMsiTIGR00985, 3a0801s04tom, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTOM20_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q15388
Secondary accession number(s): A8K195, Q498B3, Q6IBT4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: August 12, 2020
This is version 190 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families
  6. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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