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Entry version 174 (12 Aug 2020)
Sequence version 3 (02 Nov 2010)
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Protein

Pregnancy-specific beta-1-glycoprotein 5

Gene

PSG5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q15238

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-202733, Cell surface interactions at the vascular wall

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Pregnancy-specific beta-1-glycoprotein 5
Short name:
PS-beta-G-5
Short name:
PSBG-5
Short name:
Pregnancy-specific glycoprotein 5
Alternative name(s):
Fetal liver non-specific cross-reactive antigen 3
Short name:
FL-NCA-3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PSG5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000204941.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:9522, PSG5

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
176394, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q15238

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
5673

Open Targets

More...
OpenTargetsi
ENSG00000204941

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA33867

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q15238, Tbio

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB00523, Alitretinoin

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PSG5

Domain mapping of disease mutations (DMDM)

More...
DMDMi
311033414

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 34Sequence analysisAdd BLAST34
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001491235 – 335Pregnancy-specific beta-1-glycoprotein 5Add BLAST301

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi104N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi111N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi169 ↔ 217Curated
Glycosylationi175N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi210N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi261 ↔ 301Curated

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q15238

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q15238

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q15238

PeptideAtlas

More...
PeptideAtlasi
Q15238

PRoteomics IDEntifications database

More...
PRIDEi
Q15238

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
60495

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q15238, 4 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q15238

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q15238

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Synthesized by syncytiotrophoblast of the placenta.

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

PSBG are produced in high quantity during pregnancy.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000204941, Expressed in chorionic villus and 136 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q15238, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q15238, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000204941, Tissue enriched (placenta)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
111648, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q15238, 3 interactors

Molecular INTeraction database

More...
MINTi
Q15238

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000382334

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q15238, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q15238

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 144Ig-like V-typeAdd BLAST110
Domaini147 – 234Ig-like C2-type 1Add BLAST88
Domaini239 – 317Ig-like C2-type 2Add BLAST79

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi127 – 129Cell attachment siteSequence analysis3

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the immunoglobulin superfamily. CEA family.Curated

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RWXZ, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00960000186634

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q15238

KEGG Orthology (KO)

More...
KOi
K06500

Database of Orthologous Groups

More...
OrthoDBi
998214at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q15238

TreeFam database of animal gene trees

More...
TreeFami
TF336859

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR013106, Ig_V-set

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13895, Ig_2, 2 hits
PF07686, V-set, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00409, IG, 3 hits
SM00408, IGc2, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726, SSF48726, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835, IG_LIKE, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q15238-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGPLSAPPCT QHITWKGLLL TASLLNFWNL PITAQVTIEA LPPKVSEGKD
60 70 80 90 100
VLLLVHNLPQ NLAGYIWYKG QLMDLYHYIT SYVVDGQINI YGPAYTGRET
110 120 130 140 150
VYSNASLLIQ NVTREDAGSY TLHIIKRGDR TRGVTGYFTF NLYLKLPKPY
160 170 180 190 200
ITINNSKPRE NKDVLAFTCE PKSENYTYIW WLNGQSLPVS PRVKRPIENR
210 220 230 240 250
ILILPSVTRN ETGPYECEIR DRDGGMRSDP VTLNVLYGPD LPSIYPSFTY
260 270 280 290 300
YRSGENLYLS CFAESNPPAE YFWTINGKFQ QSGQKLSIPQ ITTKHRGLYT
310 320 330
CSVRNSATGK ESSKSMTVEV SAPSGIGRLP LLNPI
Length:335
Mass (Da):37,713
Last modified:November 2, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE14EA6E9DAA88296
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7EQY3E7EQY3_HUMAN
Pregnancy-specific beta-1-glycoprot...
PSG5
333Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R1G9M0R1G9_HUMAN
Pregnancy-specific beta-1-glycoprot...
PSG5
428Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PC55E9PC55_HUMAN
Pregnancy-specific beta-1-glycoprot...
PSG5
157Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti15W → C in AAA60205 (PubMed:1922019).Curated1
Sequence conflicti20L → V in AAA36514 (PubMed:2735907).Curated1
Sequence conflicti195R → Q no nucleotide entry (PubMed:2789512).Curated1
Sequence conflicti195R → Q in AAH12607 (PubMed:15489334).Curated1
Sequence conflicti232T → S in AAA60205 (PubMed:1922019).Curated1
Sequence conflicti232T → S in AAA36514 (PubMed:2735907).Curated1
Sequence conflicti240D → Y in AAA36514 (PubMed:2735907).Curated1
Sequence conflicti288I → M in AAA36514 (PubMed:2735907).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06026018L → V4 PublicationsCorresponds to variant dbSNP:rs8107936Ensembl.1
Natural variantiVAR_016041154N → K2 PublicationsCorresponds to variant dbSNP:rs1058259Ensembl.1
Natural variantiVAR_060261168T → I. Corresponds to variant dbSNP:rs5013158Ensembl.1
Natural variantiVAR_060262227R → H4 PublicationsCorresponds to variant dbSNP:rs1058285Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M73713 mRNA Translation: AAA60205.1
M25384 mRNA Translation: AAA36514.1
AC005392 Genomic DNA No translation available.
BC012607 mRNA Translation: AAH12607.1
AH007626 Genomic DNA Translation: AAD28500.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12617.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A33514
B33251
C54312

NCBI Reference Sequences

More...
RefSeqi
NP_001123486.1, NM_001130014.1
NP_002772.3, NM_002781.3
XP_016882492.1, XM_017027003.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000342951; ENSP00000344413; ENSG00000204941
ENST00000366175; ENSP00000382334; ENSG00000204941
ENST00000407356; ENSP00000386008; ENSG00000204941

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5673

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:5673

UCSC genome browser

More...
UCSCi
uc002ovu.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M73713 mRNA Translation: AAA60205.1
M25384 mRNA Translation: AAA36514.1
AC005392 Genomic DNA No translation available.
BC012607 mRNA Translation: AAH12607.1
AH007626 Genomic DNA Translation: AAD28500.1
CCDSiCCDS12617.1
PIRiA33514
B33251
C54312
RefSeqiNP_001123486.1, NM_001130014.1
NP_002772.3, NM_002781.3
XP_016882492.1, XM_017027003.1

3D structure databases

SMRiQ15238
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi111648, 4 interactors
IntActiQ15238, 3 interactors
MINTiQ15238
STRINGi9606.ENSP00000382334

Chemistry databases

DrugBankiDB00523, Alitretinoin

PTM databases

GlyGeniQ15238, 4 sites
iPTMnetiQ15238
PhosphoSitePlusiQ15238

Polymorphism and mutation databases

BioMutaiPSG5
DMDMi311033414

Proteomic databases

jPOSTiQ15238
MassIVEiQ15238
PaxDbiQ15238
PeptideAtlasiQ15238
PRIDEiQ15238
ProteomicsDBi60495

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
21553, 56 antibodies

The DNASU plasmid repository

More...
DNASUi
5673

Genome annotation databases

EnsembliENST00000342951; ENSP00000344413; ENSG00000204941
ENST00000366175; ENSP00000382334; ENSG00000204941
ENST00000407356; ENSP00000386008; ENSG00000204941
GeneIDi5673
KEGGihsa:5673
UCSCiuc002ovu.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5673
DisGeNETi5673
EuPathDBiHostDB:ENSG00000204941.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PSG5
HGNCiHGNC:9522, PSG5
HPAiENSG00000204941, Tissue enriched (placenta)
MIMi176394, gene
neXtProtiNX_Q15238
OpenTargetsiENSG00000204941
PharmGKBiPA33867

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502RWXZ, Eukaryota
GeneTreeiENSGT00960000186634
InParanoidiQ15238
KOiK06500
OrthoDBi998214at2759
PhylomeDBiQ15238
TreeFamiTF336859

Enzyme and pathway databases

PathwayCommonsiQ15238
ReactomeiR-HSA-202733, Cell surface interactions at the vascular wall

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
5673, 27 hits in 861 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
PSG5, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
PSG5

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
5673
PharosiQ15238, Tbio

Protein Ontology

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PROi
PR:Q15238
RNActiQ15238, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000204941, Expressed in chorionic villus and 136 other tissues
ExpressionAtlasiQ15238, baseline and differential
GenevisibleiQ15238, HS

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR013106, Ig_V-set
PfamiView protein in Pfam
PF13895, Ig_2, 2 hits
PF07686, V-set, 1 hit
SMARTiView protein in SMART
SM00409, IG, 3 hits
SM00408, IGc2, 2 hits
SUPFAMiSSF48726, SSF48726, 3 hits
PROSITEiView protein in PROSITE
PS50835, IG_LIKE, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPSG5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q15238
Secondary accession number(s): Q15239, Q96QJ1, Q9UQ75
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 2, 2010
Last modified: August 12, 2020
This is version 174 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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