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Protein

Transcription elongation factor A protein-like 1

Gene

TCEAL1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA-binding transcription factor activity Source: ProtInc
  • WW domain binding Source: GO_Central

GO - Biological processi

  • negative regulation of transcription by RNA polymerase II Source: ProtInc

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription elongation factor A protein-like 1
Short name:
TCEA-like protein 1
Alternative name(s):
Nuclear phosphoprotein p21/SIIR
Transcription elongation factor S-II protein-like 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TCEAL1
Synonyms:SIIR
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000172465.13

Human Gene Nomenclature Database

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HGNCi
HGNC:11616 TCEAL1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300237 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q15170

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi31 – 32SS → AA: Slight decrease of transcriptional repression. 1 Publication2
Mutagenesisi36 – 37SS → AA: Loss of transcriptional repression. 1 Publication2
Mutagenesisi41 – 42SS → AA: No effect on transcriptional repression. 1 Publication2
Mutagenesisi47 – 48SS → AA: Slight decrease of transcriptional repression. 1 Publication2

Organism-specific databases

DisGeNET

More...
DisGeNETi
9338

Open Targets

More...
OpenTargetsi
ENSG00000172465

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36375

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TCEAL1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
108935936

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002392031 – 157Transcription elongation factor A protein-like 1Add BLAST157

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei31Phosphoserine1 Publication1
Modified residuei32Phosphoserine1 Publication1
Modified residuei36Phosphoserine1 Publication1
Modified residuei37Phosphoserine1 Publication1
Modified residuei41Phosphoserine1 Publication1
Modified residuei42Phosphoserine1 Publication1
Modified residuei47Phosphoserine1 Publication1
Modified residuei48Phosphoserine1 Publication1
Isoform 2 (identifier: Q15170-2)
Modified residuei28PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylation of Ser-36 and Ser-37 is critical for transcriptional repression.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
Q15170

PeptideAtlas

More...
PeptideAtlasi
Q15170

PRoteomics IDEntifications database

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PRIDEi
Q15170

ProteomicsDB human proteome resource

More...
ProteomicsDBi
60479
60480 [Q15170-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q15170

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q15170

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in all tissues examined. Highly expressed in heart, ovary, prostate and skeletal muscle. Moderately expressed in brain, placenta, testis and small intestine. Weakly expressed in lung, liver and spleen. Expressed in several cancer cell lines.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000172465 Expressed in 221 organ(s), highest expression level in right ovary

CleanEx database of gene expression profiles

More...
CleanExi
HS_TCEAL1

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q15170 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA057345
HPA060384

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
114745, 60 interactors

Protein interaction database and analysis system

More...
IntActi
Q15170, 20 interactors

Molecular INTeraction database

More...
MINTi
Q15170

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q15170

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi15 – 72Arg/Ser-richAdd BLAST58

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TFS-II family. TFA subfamily.Curated

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154402

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231344

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG094029

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q15170

Identification of Orthologs from Complete Genome Data

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OMAi
ERPPMEQ

Database of Orthologous Groups

More...
OrthoDBi
EOG091G13IU

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q15170

TreeFam database of animal gene trees

More...
TreeFami
TF336871

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR010370 TCEAL1
IPR021156 TF_A-like/BEX

The PANTHER Classification System

More...
PANTHERi
PTHR14754:SF12 PTHR14754:SF12, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04538 BEX, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q15170-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDKPRKENEE EPQSRPRPMR RGLRWSTLPK SSPPRSSLRR SSPRRRSSFL
60 70 80 90 100
RSSCLSSCLR CSSRRTPSAG LSRKDLFEGR PPMEQPPCGV GKHKLEEGSF
110 120 130 140 150
KERLARSRPQ FRGDIHGRNL SNEEMIQAAD ELEEMKRVRN KLMIMHWKAK

RSRPYPI
Length:157
Mass (Da):18,354
Last modified:May 30, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i09D86B3735283B27
GO
Isoform 2 (identifier: Q15170-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     15-69: RPRPMRRGLR...RCSSRRTPSA → APKTDEERPP...LLSEERPPQE

Show »
Length:159
Mass (Da):18,641
Checksum:iFB45224005BA6B5A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti79G → V (PubMed:8206389).Curated1
Sequence conflicti79G → V (PubMed:10051408).Curated1
Sequence conflicti94K → N (PubMed:8206389).Curated1
Sequence conflicti94K → N (PubMed:10051408).Curated1
Sequence conflicti99S → I (PubMed:8206389).Curated1
Sequence conflicti99S → I (PubMed:10051408).Curated1
Sequence conflicti148K → R (PubMed:8206389).Curated1
Sequence conflicti148K → R (PubMed:10051408).Curated1
Sequence conflicti152 – 153SR → GG (PubMed:8206389).Curated2
Sequence conflicti152 – 153SR → GG (PubMed:10051408).Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0572705R → C. Corresponds to variant dbSNP:rs34421776Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01910815 – 69RPRPM…RTPSA → APKTDEERPPVEHSPEKQSP EEQSSEEQSSEEEFFPEELL PELLPEMLLSEERPPQE in isoform 2. 1 PublicationAdd BLAST55

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M99701 mRNA Translation: AAA60149.1
AF095906 Genomic DNA Translation: AAD17840.1
AL049610 Genomic DNA No translation available.
BC000809 mRNA Translation: AAH00809.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS35358.1 [Q15170-2]

Protein sequence database of the Protein Information Resource

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PIRi
I53785

NCBI Reference Sequences

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RefSeqi
NP_001006640.1, NM_001006639.1 [Q15170-2]
NP_001006641.1, NM_001006640.1 [Q15170-2]
NP_004771.2, NM_004780.2 [Q15170-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.95243

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000372624; ENSP00000361707; ENSG00000172465 [Q15170-2]
ENST00000372625; ENSP00000361708; ENSG00000172465 [Q15170-2]
ENST00000372626; ENSP00000361709; ENSG00000172465 [Q15170-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9338

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9338

UCSC genome browser

More...
UCSCi
uc004eks.4 human [Q15170-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M99701 mRNA Translation: AAA60149.1
AF095906 Genomic DNA Translation: AAD17840.1
AL049610 Genomic DNA No translation available.
BC000809 mRNA Translation: AAH00809.1
CCDSiCCDS35358.1 [Q15170-2]
PIRiI53785
RefSeqiNP_001006640.1, NM_001006639.1 [Q15170-2]
NP_001006641.1, NM_001006640.1 [Q15170-2]
NP_004771.2, NM_004780.2 [Q15170-2]
UniGeneiHs.95243

3D structure databases

ProteinModelPortaliQ15170
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi114745, 60 interactors
IntActiQ15170, 20 interactors
MINTiQ15170

PTM databases

iPTMnetiQ15170
PhosphoSitePlusiQ15170

Polymorphism and mutation databases

BioMutaiTCEAL1
DMDMi108935936

Proteomic databases

MaxQBiQ15170
PeptideAtlasiQ15170
PRIDEiQ15170
ProteomicsDBi60479
60480 [Q15170-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
9338
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000372624; ENSP00000361707; ENSG00000172465 [Q15170-2]
ENST00000372625; ENSP00000361708; ENSG00000172465 [Q15170-2]
ENST00000372626; ENSP00000361709; ENSG00000172465 [Q15170-2]
GeneIDi9338
KEGGihsa:9338
UCSCiuc004eks.4 human [Q15170-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9338
DisGeNETi9338
EuPathDBiHostDB:ENSG00000172465.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TCEAL1
HGNCiHGNC:11616 TCEAL1
HPAiHPA057345
HPA060384
MIMi300237 gene
neXtProtiNX_Q15170
OpenTargetsiENSG00000172465
PharmGKBiPA36375

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000154402
HOGENOMiHOG000231344
HOVERGENiHBG094029
InParanoidiQ15170
OMAiERPPMEQ
OrthoDBiEOG091G13IU
PhylomeDBiQ15170
TreeFamiTF336871

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TCEAL1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9338

Protein Ontology

More...
PROi
PR:Q15170

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000172465 Expressed in 221 organ(s), highest expression level in right ovary
CleanExiHS_TCEAL1
GenevisibleiQ15170 HS

Family and domain databases

InterProiView protein in InterPro
IPR010370 TCEAL1
IPR021156 TF_A-like/BEX
PANTHERiPTHR14754:SF12 PTHR14754:SF12, 1 hit
PfamiView protein in Pfam
PF04538 BEX, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTCAL1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q15170
Secondary accession number(s): Q9UJQ9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: May 30, 2006
Last modified: December 5, 2018
This is version 135 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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