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Protein

Nodal modulator 1

Gene

NOMO1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May antagonize Nodal signaling.By similarity

Caution

There are 3 copies of the NOMO gene on chromosome 16p12-p13: NOMO1, NOMO2 (AC Q5JPE7) and NOMO3 (AC P69849). All 3 are extremely similar, which makes their individual characterization difficult. Thus, most experiments probably do not discriminate between the different members. Moreover, it does not allow a clear view of which variant belongs to which of the 3 copies. The results reported in other entries may therefore apply for this protein.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nodal modulator 1
Alternative name(s):
pM5 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NOMO1
Synonyms:PM5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000103512.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30060 NOMO1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609157 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q15155

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini32 – 1155ExtracellularSequence analysisAdd BLAST1124
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1156 – 1176HelicalSequence analysisAdd BLAST21
Topological domaini1177 – 1222CytoplasmicSequence analysisAdd BLAST46

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
23420

Open Targets

More...
OpenTargetsi
ENSG00000103512

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134934458

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NOMO1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296439497

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 31Sequence analysisAdd BLAST31
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002181932 – 1222Nodal modulator 1Add BLAST1191

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi50N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi218N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi618N-linked (GlcNAc...) asparagine1 Publication1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1205PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q15155

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q15155

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q15155

PeptideAtlas

More...
PeptideAtlasi
Q15155

PRoteomics IDEntifications database

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PRIDEi
Q15155

ProteomicsDB human proteome resource

More...
ProteomicsDBi
60474

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1572

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q15155

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q15155

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q15155

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in colon tumor tissue and in adjacent normal colonic mucosa.

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

No difference between normal colonic mucosa and colon tumor tissue in mRNA expression, whereas the protein is expressed 1.5-fold more in normal colonic mucosa that in colon tumor tissue.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000103512 Expressed in 91 organ(s), highest expression level in skeletal muscle tissue

CleanEx database of gene expression profiles

More...
CleanExi
HS_NOMO1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q15155 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q15155 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB025192
HPA046697
HPA061174

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116991, 67 interactors

Protein interaction database and analysis system

More...
IntActi
Q15155, 13 interactors

Molecular INTeraction database

More...
MINTi
Q15155

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000287667

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q15155

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q15155

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1948 Eukaryota
ENOG410XTI0 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000089

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000230623

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG023764

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q15155

Database for complete collections of gene phylogenies

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PhylomeDBi
Q15155

TreeFam database of animal gene trees

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TreeFami
TF313696

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR013784 Carb-bd-like_fold
IPR008969 CarboxyPept-like_regulatory

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49452 SSF49452, 3 hits
SSF49464 SSF49464, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q15155-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLVGQGAGPL GPAVVTAAVV LLLSGVGPAH GSEDIVVGCG GFVKSDVEIN
60 70 80 90 100
YSLIEIKLYT KHGTLKYQTD CAPNNGYFMI PLYDKGDFIL KIEPPLGWSF
110 120 130 140 150
EPTTVELHVD GVSDICTKGG DINFVFTGFS VNGKVLSKGQ PLGPAGVQVS
160 170 180 190 200
LRNTGTEAKI QSTVTQPGGK FAFFKVLPGD YEILATHPTW ALKEASTTVR
210 220 230 240 250
VTNSNANAAS PLIVAGYNVS GSVRSDGEPM KGVKFLLFSS LVTKEDVLGC
260 270 280 290 300
NVSPVPGFQP QDESLVYLCY TVSREDGSFS FYSLPSGGYT VIPFYRGERI
310 320 330 340 350
TFDVAPSRLD FTVEHDSLKI EPVFHVMGFS VTGRVLNGPE GDGVPEAVVT
360 370 380 390 400
LNNQIKVKTK ADGSFRLENI TTGTYTIHAQ KEHLYFETVT IKIAPNTPQL
410 420 430 440 450
ADIIATGFSV CGQISIIRFP DTVKQMNKYK VVLSSQDKDK SLVTVETDAH
460 470 480 490 500
GSFCFKAKPG TYKVQVMVPE AETRAGLTLK PQTFPLTVTN RPMMDVAFVQ
510 520 530 540 550
FLASVSGKVS CLDTCGDLLV TLQSLSRQGE KRSLQLSGKV NAMTFTFDNV
560 570 580 590 600
LPGKYKISIM HEDWCWKNKS LEVEVLEDDM SAVEFRQTGY MLRCSLSHAI
610 620 630 640 650
TLEFYQDGNG RENVGIYNLS KGVNRFCLSK PGVYKVTPRS CHRFEQAFYT
660 670 680 690 700
YDTSSPSILT LTAIRHHVLG TITTDKMMDV TVTIKSSIDS EPALVLGPLK
710 720 730 740 750
SVQELRREQQ LAEIEARRQE REKNGNEEGE ERMTKPPVQE MVDELQGPFS
760 770 780 790 800
YDFSYWARSG EKITVTPSSK ELLFYPPSME AVVSGESCPG KLIEIHGKAG
810 820 830 840 850
LFLEGQIHPE LEGVEIVISE KGASSPLITV FTDDKGAYSV GPLHSDLEYT
860 870 880 890 900
VTSQKEGYVL TAVEGTIGDF KAYALAGVSF EIKAEDDQPL PGVLLSLSGG
910 920 930 940 950
LFRSNLLTQD NGILTFSNLS PGQYYFKPMM KEFRFEPSSQ MIEVQEGQNL
960 970 980 990 1000
KITITGYRTA YSCYGTVSSL NGEPEQGVAM EAVGQNDCSI YGEDTVTDEE
1010 1020 1030 1040 1050
GKFRLRGLLP GCVYHVQLKA EGNDHIERAL PHHRVIEVGN NDIDDVNIIV
1060 1070 1080 1090 1100
FRQINQFDLS GNVITSSEYL PTLWVKLYKS ENLDNPIQTV SLGQSLFFHF
1110 1120 1130 1140 1150
PPLLRDGENY VVLLDSTLPR SQYDYILPQV SFTAVGYHKH ITLIFNPTRK
1160 1170 1180 1190 1200
LPEQDIAQGS YIALPLTLLV LLAGYNHDKL IPLLLQLTSR LQGVRALGQA
1210 1220
ASDNSGPEDA KRQAKKQKTR RT
Length:1,222
Mass (Da):134,324
Last modified:May 18, 2010 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEE0A3BB552BAB72B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087X117A0A087X117_HUMAN
Nodal modulator 1
NOMO1
1,267Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JN29A0A0G2JN29_HUMAN
Nodal modulator 1
NOMO1
1,267Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WW46A0A087WW46_HUMAN
Nodal modulator 1
NOMO1
1,100Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JP90A0A0G2JP90_HUMAN
Nodal modulator 1
NOMO1
1,100Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BUC9H3BUC9_HUMAN
Nodal modulator 1
NOMO1
144Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti33 – 35EDI → RDL in CAA40655 (PubMed:1310294).Curated3
Sequence conflicti200R → S in CAA40655 (PubMed:1310294).Curated1
Sequence conflicti513D → N in CAA40655 (PubMed:1310294).Curated1
Sequence conflicti618N → S in CAA40655 (PubMed:1310294).Curated1
Sequence conflicti620S → F in CAA40655 (PubMed:1310294).Curated1
Sequence conflicti650T → I in CAA40655 (PubMed:1310294).Curated1
Sequence conflicti659L → F in CAA40655 (PubMed:1310294).Curated1
Sequence conflicti1141I → T in CAA40655 (PubMed:1310294).Curated1
Sequence conflicti1196A → V in AAH65535 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_013312404I → V1 PublicationCorresponds to variant dbSNP:rs2561962Ensembl.1
Natural variantiVAR_013313458K → N1 PublicationCorresponds to variant dbSNP:rs1345150579Ensembl.1
Natural variantiVAR_013314490N → D1 PublicationCorresponds to variant dbSNP:rs1062412Ensembl.1
Natural variantiVAR_022551493M → V. Corresponds to variant dbSNP:rs141860762Ensembl.1
Natural variantiVAR_056956580M → V. Corresponds to variant dbSNP:rs17356851Ensembl.1
Natural variantiVAR_060370583V → A1 PublicationCorresponds to variant dbSNP:rs17855981Ensembl.1
Natural variantiVAR_0114961081E → K1 PublicationCorresponds to variant dbSNP:rs200317822Ensembl.1
Natural variantiVAR_0133151141I → F1 PublicationCorresponds to variant dbSNP:rs376397163Ensembl.1
Natural variantiVAR_0133161195R → G1 PublicationCorresponds to variant dbSNP:rs9330Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC136443 Genomic DNA No translation available.
BC065535 mRNA Translation: AAH65535.1
X57398 mRNA Translation: CAA40655.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS10556.1

Protein sequence database of the Protein Information Resource

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PIRi
S21977

NCBI Reference Sequences

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RefSeqi
NP_055102.3, NM_014287.3

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.743963

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000287667; ENSP00000287667; ENSG00000103512
ENST00000619292; ENSP00000482008; ENSG00000274779

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23420

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:23420

UCSC genome browser

More...
UCSCi
uc002dcv.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC136443 Genomic DNA No translation available.
BC065535 mRNA Translation: AAH65535.1
X57398 mRNA Translation: CAA40655.1
CCDSiCCDS10556.1
PIRiS21977
RefSeqiNP_055102.3, NM_014287.3
UniGeneiHs.743963

3D structure databases

ProteinModelPortaliQ15155
SMRiQ15155
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116991, 67 interactors
IntActiQ15155, 13 interactors
MINTiQ15155
STRINGi9606.ENSP00000287667

PTM databases

GlyConnecti1572
iPTMnetiQ15155
PhosphoSitePlusiQ15155
SwissPalmiQ15155

Polymorphism and mutation databases

BioMutaiNOMO1
DMDMi296439497

Proteomic databases

EPDiQ15155
MaxQBiQ15155
PaxDbiQ15155
PeptideAtlasiQ15155
PRIDEiQ15155
ProteomicsDBi60474

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000287667; ENSP00000287667; ENSG00000103512
ENST00000619292; ENSP00000482008; ENSG00000274779
GeneIDi23420
KEGGihsa:23420
UCSCiuc002dcv.4 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
23420
DisGeNETi23420
EuPathDBiHostDB:ENSG00000103512.14

GeneCards: human genes, protein and diseases

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GeneCardsi
NOMO1

H-Invitational Database, human transcriptome db

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H-InvDBi
HIX0023257
HGNCiHGNC:30060 NOMO1
HPAiCAB025192
HPA046697
HPA061174
MIMi609157 gene
neXtProtiNX_Q15155
OpenTargetsiENSG00000103512
PharmGKBiPA134934458

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1948 Eukaryota
ENOG410XTI0 LUCA
GeneTreeiENSGT00390000000089
HOGENOMiHOG000230623
HOVERGENiHBG023764
InParanoidiQ15155
PhylomeDBiQ15155
TreeFamiTF313696

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
NOMO1 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
NOMO1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
23420

Protein Ontology

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PROi
PR:Q15155

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000103512 Expressed in 91 organ(s), highest expression level in skeletal muscle tissue
CleanExiHS_NOMO1
ExpressionAtlasiQ15155 baseline and differential
GenevisibleiQ15155 HS

Family and domain databases

InterProiView protein in InterPro
IPR013784 Carb-bd-like_fold
IPR008969 CarboxyPept-like_regulatory
SUPFAMiSSF49452 SSF49452, 3 hits
SSF49464 SSF49464, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNOMO1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q15155
Secondary accession number(s): P78421, Q8IW21, Q96DG0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: May 18, 2010
Last modified: November 7, 2018
This is version 175 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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