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UniProtKB - Q15072 (OZF_HUMAN)

Entry version 180 (07 Apr 2021)
Sequence version 2 (06 Mar 2007)
Previous versions | rss
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Protein

Zinc finger protein OZF

Gene

ZNF146

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri16 – 38C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri44 – 66C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri72 – 94C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri100 – 122C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri128 – 150C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri156 – 178C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri184 – 206C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri212 – 234C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri240 – 262C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri268 – 290C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q15072

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein OZF
Alternative name(s):
Only zinc finger protein
Zinc finger protein 146
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF146
Synonyms:OZF
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:12931, ZNF146

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		601505, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q15072

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000167635.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi157K → R: Induces a decrease in sumoylation. Induces a strong decrease but does not abolishes sumoylation; when associated with R-169. 1 Publication1
Mutagenesisi169K → R: Induces a decrease in sumoylation. Induces a strong decrease but does not abolishes sumoylation; when associated with R-157. 1 Publication1

Organism-specific databases

DisGeNET

More...DisGeNETi		7705

Open Targets

More...OpenTargetsi		ENSG00000167635

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA37518

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q15072, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF146

Domain mapping of disease mutations (DMDM)

More...DMDMi		134048495

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000472761 – 292Zinc finger protein OZFAdd BLAST292

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki28Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki51Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki56Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki157Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)By similarity
Cross-linki169Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)By similarity
Cross-linki173Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Sumoylated.1 Publication

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q15072

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q15072

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q15072

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q15072

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q15072

PeptideAtlas

More...PeptideAtlasi		Q15072

PRoteomics IDEntifications database

More...PRIDEi		Q15072

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		60426

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q15072

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q15072

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpressed in 80% of colorectal cancers.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000167635, Expressed in metanephros and 254 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q15072, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000167635, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds DNA.

Interacts with SUMO conjugating enzyme UBC9/UBE2I.

Interacts with the telomeric protein TERF2IP.

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		113499, 38 interactors

Protein interaction database and analysis system

More...IntActi		Q15072, 17 interactors

Molecular INTeraction database

More...MINTi		Q15072

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000400391

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q15072, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q15072

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni212 – 292Interaction with TERF2IP1 PublicationAdd BLAST81

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri16 – 38C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri44 – 66C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri72 – 94C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri100 – 122C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri128 – 150C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri156 – 178C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri184 – 206C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri212 – 234C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri240 – 262C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri268 – 290C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000162671

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q15072

Identification of Orthologs from Complete Genome Data

More...OMAi		GGSPFAC

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q15072

TreeFam database of animal gene trees

More...TreeFami		TF337055

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 6 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q15072-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHLSQQRIY SGENPFACKV CGKVFSHKSN LTEHEHFHTR EKPFECNECG 
        60         70         80         90        100
KAFSQKQYVI KHQNTHTGEK LFECNECGKS FSQKENLLTH QKIHTGEKPF 
       110        120        130        140        150
ECKDCGKAFI QKSNLIRHQR THTGEKPFVC KECGKTFSGK SNLTEHEKIH 
       160        170        180        190        200
IGEKPFKCSE CGTAFGQKKY LIKHQNIHTG EKPYECNECG KAFSQRTSLI 
       210        220        230        240        250
VHVRIHSGDK PYECNVCGKA FSQSSSLTVH VRSHTGEKPY GCNECGKAFS 
       260        270        280        290 
QFSTLALHLR IHTGKKPYQC SECGKAFSQK SHHIRHQKIH TH
Length:292
Mass (Da):33,308
Last modified:March 6, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD5062375D261B971
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0237468R → K3 PublicationsCorresponds to variant dbSNP:rs2070132Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X70394 mRNA Translation: CAA49844.1
AJ011806 Genomic DNA Translation: CAB41967.1
AC012617 Genomic DNA No translation available.
BC110500 mRNA Translation: AAI10501.1
BC110501 mRNA Translation: AAI10502.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12492.1

Protein sequence database of the Protein Information Resource

More...PIRi		S43826

NCBI Reference Sequences

More...RefSeqi		NP_001093108.1, NM_001099638.1
NP_001093109.1, NM_001099639.1
NP_009076.2, NM_007145.2
XP_005259271.1, XM_005259214.2
XP_016882733.1, XM_017027244.1
XP_016882734.1, XM_017027245.1
XP_016882735.1, XM_017027246.1
XP_016882736.1, XM_017027247.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000443387; ENSP00000392095; ENSG00000167635
ENST00000456324; ENSP00000400391; ENSG00000167635

Database of genes from NCBI RefSeq genomes

More...GeneIDi		7705

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:7705

UCSC genome browser

More...UCSCi		uc002odq.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X70394 mRNA Translation: CAA49844.1
AJ011806 Genomic DNA Translation: CAB41967.1
AC012617 Genomic DNA No translation available.
BC110500 mRNA Translation: AAI10501.1
BC110501 mRNA Translation: AAI10502.1
CCDSiCCDS12492.1
PIRiS43826
RefSeqiNP_001093108.1, NM_001099638.1
NP_001093109.1, NM_001099639.1
NP_009076.2, NM_007145.2
XP_005259271.1, XM_005259214.2
XP_016882733.1, XM_017027244.1
XP_016882734.1, XM_017027245.1
XP_016882735.1, XM_017027246.1
XP_016882736.1, XM_017027247.1

3D structure databases

SMRiQ15072
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi113499, 38 interactors
IntActiQ15072, 17 interactors
MINTiQ15072
STRINGi9606.ENSP00000400391

PTM databases

iPTMnetiQ15072
PhosphoSitePlusiQ15072

Genetic variation databases

BioMutaiZNF146
DMDMi134048495

Proteomic databases

EPDiQ15072
jPOSTiQ15072
MassIVEiQ15072
MaxQBiQ15072
PaxDbiQ15072
PeptideAtlasiQ15072
PRIDEiQ15072
ProteomicsDBi60426

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		929, 158 antibodies

The DNASU plasmid repository

More...DNASUi		7705

Genome annotation databases

EnsembliENST00000443387; ENSP00000392095; ENSG00000167635
ENST00000456324; ENSP00000400391; ENSG00000167635
GeneIDi7705
KEGGihsa:7705
UCSCiuc002odq.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		7705
DisGeNETi7705

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF146
HGNCiHGNC:12931, ZNF146
HPAiENSG00000167635, Low tissue specificity
MIMi601505, gene
neXtProtiNX_Q15072
OpenTargetsiENSG00000167635
PharmGKBiPA37518
VEuPathDBiHostDB:ENSG00000167635.11

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000162671
HOGENOMiCLU_002678_2_1_1
InParanoidiQ15072
OMAiGGSPFAC
OrthoDBi1318335at2759
PhylomeDBiQ15072
TreeFamiTF337055

Enzyme and pathway databases

PathwayCommonsiQ15072

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		7705, 5 hits in 987 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF146, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		ZNF146

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		7705
PharosiQ15072, Tbio

Protein Ontology

More...PROi		PR:Q15072
RNActiQ15072, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000167635, Expressed in metanephros and 254 other tissues
GenevisibleiQ15072, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 10 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 10 hits
SUPFAMiSSF57667, SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOZF_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q15072
Secondary accession number(s): Q2TB94
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: March 6, 2007
Last modified: April 7, 2021
This is version 180 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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