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Entry version 184 (13 Nov 2019)
Sequence version 1 (01 Nov 1996)
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Protein

Mortality factor 4-like protein 2

Gene

MORF4L2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator
Biological processDNA damage, DNA repair, Growth regulation, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-3214847 HATs acetylate histones

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mortality factor 4-like protein 2
Alternative name(s):
MORF-related gene X protein
Protein MSL3-2
Transcription factor-like protein MRGX
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MORF4L2
Synonyms:KIAA0026, MRGX
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:16849 MORF4L2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300409 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q15014

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi132 – 136Missing : Abrogates both transcriptional activation and repression by MORF4L2. 1 Publication5
Mutagenesisi263L → A: Abrogates both transcriptional activation and repression by MORF4L2. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
9643

Open Targets

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OpenTargetsi
ENSG00000123562

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134925837

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q15014

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MORF4L2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
3123049

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000887681 – 288Mortality factor 4-like protein 2Add BLAST288

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei71PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q15014

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q15014

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q15014

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q15014

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q15014

PeptideAtlas

More...
PeptideAtlasi
Q15014

PRoteomics IDEntifications database

More...
PRIDEi
Q15014

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
60366

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q15014

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q15014

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000123562 Expressed in 244 organ(s), highest expression level in pituitary gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q15014 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q15014 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA031872
HPA054102

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41 and VPS72/YL1. The NuA4 complex interacts with MYC and the adenovirus E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack the KAT5/TIP60 catalytic subunit, but which include the SWI/SNF related protein SRCAP.

Component of the MSIN3A histone deacetylase complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46.

Interacts with MRFAP1 and RB1. May also interact with one or more as yet undefined members of the TLE (transducin-like enhancer of split) family of transcriptional repressors.

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115001, 112 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-978 NuA4 histone acetyltransferase complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q15014

Protein interaction database and analysis system

More...
IntActi
Q15014, 88 interactors

Molecular INTeraction database

More...
MINTi
Q15014

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000394417

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q15014

Database of comparative protein structure models

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ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini117 – 288MRGPROSITE-ProRule annotationAdd BLAST172

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3001 Eukaryota
ENOG410XR9F LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00950000182965

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000190863

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q15014

KEGG Orthology (KO)

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KOi
K11342

Identification of Orthologs from Complete Genome Data

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OMAi
RGNMQRS

Database of Orthologous Groups

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OrthoDBi
1624495at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
Q15014

TreeFam database of animal gene trees

More...
TreeFami
TF323400

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.274.30, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR008676 MRG
IPR038217 MRG_C_sf
IPR026541 MRG_dom
IPR038012 MRGX

The PANTHER Classification System

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PANTHERi
PTHR10880 PTHR10880, 1 hit
PTHR10880:SF25 PTHR10880:SF25, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05712 MRG, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF038133 HAT_Nua4_EAF3/MRG15, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51640 MRG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q15014-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN
60 70 80 90 100
LEPALPGRWG GRSAENPPSG SVRKTRKNKQ KTPGNGDGGS TSEAPQPPRK
110 120 130 140 150
KRARADPTVE SEEAFKNRME VKVKIPEELK PWLVEDWDLV TRQKQLFQLP
160 170 180 190 200
AKKNVDAILE EYANCKKSQG NVDNKEYAVN EVVAGIKEYF NVMLGTQLLY
210 220 230 240 250
KFERPQYAEI LLAHPDAPMS QVYGAPHLLR LFVRIGAMLA YTPLDEKSLA
260 270 280
LLLGYLHDFL KYLAKNSASL FTASDYKVAS AEYHRKAL
Length:288
Mass (Da):32,308
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC9EFF517C76A565D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5JXX1Q5JXX1_HUMAN
Mortality factor 4-like protein 2
MORF4L2
158Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5JXX2Q5JXX2_HUMAN
Mortality factor 4-like protein 2
MORF4L2
177Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5JXX6Q5JXX6_HUMAN
Mortality factor 4-like protein 2
MORF4L2
67Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MT59A0A0A0MT59_HUMAN
Mortality factor 4-like protein 2
MORF4L2
237Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF100620 mRNA Translation: AAD29873.1
AF167174 mRNA Translation: AAF80855.1
D14812 mRNA Translation: BAA03553.1
AK056012 mRNA Translation: BAG51604.1
AL049610 Genomic DNA No translation available.
CH471190 Genomic DNA Translation: EAW54698.1
CH471190 Genomic DNA Translation: EAW54699.1
CH471190 Genomic DNA Translation: EAW54700.1
CH471190 Genomic DNA Translation: EAW54701.1
BC056899 mRNA Translation: AAH56899.1
BC093013 mRNA Translation: AAH93013.1
AB050778 mRNA Translation: BAC22659.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14512.1

NCBI Reference Sequences

More...
RefSeqi
NP_001135890.1, NM_001142418.1
NP_001135891.1, NM_001142419.1
NP_001135892.1, NM_001142420.1
NP_001135893.1, NM_001142421.1
NP_001135894.1, NM_001142422.1
NP_001135895.1, NM_001142423.1
NP_001135896.1, NM_001142424.1
NP_001135897.1, NM_001142425.1
NP_001135898.1, NM_001142426.1
NP_001135899.1, NM_001142427.1
NP_001135900.1, NM_001142428.1
NP_001135901.1, NM_001142429.1
NP_001135902.1, NM_001142430.1
NP_001135903.1, NM_001142431.1
NP_001135904.1, NM_001142432.1
NP_036418.1, NM_012286.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000360458; ENSP00000353643; ENSG00000123562
ENST00000422154; ENSP00000394417; ENSG00000123562
ENST00000433176; ENSP00000415476; ENSG00000123562
ENST00000441076; ENSP00000391969; ENSG00000123562
ENST00000451301; ENSP00000410532; ENSG00000123562

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9643

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9643

UCSC genome browser

More...
UCSCi
uc004ekx.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF100620 mRNA Translation: AAD29873.1
AF167174 mRNA Translation: AAF80855.1
D14812 mRNA Translation: BAA03553.1
AK056012 mRNA Translation: BAG51604.1
AL049610 Genomic DNA No translation available.
CH471190 Genomic DNA Translation: EAW54698.1
CH471190 Genomic DNA Translation: EAW54699.1
CH471190 Genomic DNA Translation: EAW54700.1
CH471190 Genomic DNA Translation: EAW54701.1
BC056899 mRNA Translation: AAH56899.1
BC093013 mRNA Translation: AAH93013.1
AB050778 mRNA Translation: BAC22659.1
CCDSiCCDS14512.1
RefSeqiNP_001135890.1, NM_001142418.1
NP_001135891.1, NM_001142419.1
NP_001135892.1, NM_001142420.1
NP_001135893.1, NM_001142421.1
NP_001135894.1, NM_001142422.1
NP_001135895.1, NM_001142423.1
NP_001135896.1, NM_001142424.1
NP_001135897.1, NM_001142425.1
NP_001135898.1, NM_001142426.1
NP_001135899.1, NM_001142427.1
NP_001135900.1, NM_001142428.1
NP_001135901.1, NM_001142429.1
NP_001135902.1, NM_001142430.1
NP_001135903.1, NM_001142431.1
NP_001135904.1, NM_001142432.1
NP_036418.1, NM_012286.2

3D structure databases

SMRiQ15014
ModBaseiSearch...

Protein-protein interaction databases

BioGridi115001, 112 interactors
ComplexPortaliCPX-978 NuA4 histone acetyltransferase complex
CORUMiQ15014
IntActiQ15014, 88 interactors
MINTiQ15014
STRINGi9606.ENSP00000394417

PTM databases

iPTMnetiQ15014
PhosphoSitePlusiQ15014

Polymorphism and mutation databases

BioMutaiMORF4L2
DMDMi3123049

Proteomic databases

EPDiQ15014
jPOSTiQ15014
MassIVEiQ15014
MaxQBiQ15014
PaxDbiQ15014
PeptideAtlasiQ15014
PRIDEiQ15014
ProteomicsDBi60366

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
9643

Genome annotation databases

EnsembliENST00000360458; ENSP00000353643; ENSG00000123562
ENST00000422154; ENSP00000394417; ENSG00000123562
ENST00000433176; ENSP00000415476; ENSG00000123562
ENST00000441076; ENSP00000391969; ENSG00000123562
ENST00000451301; ENSP00000410532; ENSG00000123562
GeneIDi9643
KEGGihsa:9643
UCSCiuc004ekx.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9643
DisGeNETi9643

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MORF4L2
HGNCiHGNC:16849 MORF4L2
HPAiHPA031872
HPA054102
MIMi300409 gene
neXtProtiNX_Q15014
OpenTargetsiENSG00000123562
PharmGKBiPA134925837

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3001 Eukaryota
ENOG410XR9F LUCA
GeneTreeiENSGT00950000182965
HOGENOMiHOG000190863
InParanoidiQ15014
KOiK11342
OMAiRGNMQRS
OrthoDBi1624495at2759
PhylomeDBiQ15014
TreeFamiTF323400

Enzyme and pathway databases

ReactomeiR-HSA-3214847 HATs acetylate histones

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
MORF4L2 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
MORF4L2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
9643
PharosiQ15014

Protein Ontology

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PROi
PR:Q15014

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000123562 Expressed in 244 organ(s), highest expression level in pituitary gland
ExpressionAtlasiQ15014 baseline and differential
GenevisibleiQ15014 HS

Family and domain databases

Gene3Di1.10.274.30, 1 hit
InterProiView protein in InterPro
IPR008676 MRG
IPR038217 MRG_C_sf
IPR026541 MRG_dom
IPR038012 MRGX
PANTHERiPTHR10880 PTHR10880, 1 hit
PTHR10880:SF25 PTHR10880:SF25, 1 hit
PfamiView protein in Pfam
PF05712 MRG, 1 hit
PIRSFiPIRSF038133 HAT_Nua4_EAF3/MRG15, 1 hit
PROSITEiView protein in PROSITE
PS51640 MRG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMO4L2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q15014
Secondary accession number(s): B3KP92
, D3DXA5, Q567V0, Q8J026
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: November 13, 2019
This is version 184 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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