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UniProtKB - Q14DL0 (UBQLN_MOUSE)
Protein
Ubiquilin-like protein
Gene
Ubqlnl
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- polyubiquitin modification-dependent protein binding Source: GO_Central
GO - Biological processi
- ubiquitin-dependent protein catabolic process Source: GO_Central
Names & Taxonomyi
Protein namesi | Recommended name: Ubiquilin-like protein |
Gene namesi | Name:Ubqlnl |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2685336, Ubqlnl |
VEuPathDBi | HostDB:ENSMUSG00000051437 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000307792 | 1 – 610 | Ubiquilin-like proteinAdd BLAST | 610 |
Proteomic databases
PaxDbi | Q14DL0 |
PRIDEi | Q14DL0 |
ProteomicsDBi | 297796 |
PTM databases
iPTMneti | Q14DL0 |
PhosphoSitePlusi | Q14DL0 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000051437, Expressed in testis and 28 other tissues |
Genevisiblei | Q14DL0, MM |
Interactioni
GO - Molecular functioni
- polyubiquitin modification-dependent protein binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000056365 |
Miscellaneous databases
RNActi | Q14DL0, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q14DL0 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q14DL0 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 31 – 105 | Ubiquitin-likePROSITE-ProRule annotationAdd BLAST | 75 | |
Domaini | 562 – 607 | UBAAdd BLAST | 46 |
Phylogenomic databases
eggNOGi | KOG0010, Eukaryota |
GeneTreei | ENSGT00940000163345 |
HOGENOMi | CLU_024293_4_0_1 |
InParanoidi | Q14DL0 |
OMAi | MLFMSMP |
OrthoDBi | 1553668at2759 |
PhylomeDBi | Q14DL0 |
TreeFami | TF314412 |
Family and domain databases
InterProi | View protein in InterPro IPR009060, UBA-like_sf IPR000626, Ubiquitin-like_dom IPR029071, Ubiquitin-like_domsf |
Pfami | View protein in Pfam PF00240, ubiquitin, 1 hit |
SMARTi | View protein in SMART SM00213, UBQ, 1 hit |
SUPFAMi | SSF46934, SSF46934, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS50053, UBIQUITIN_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q14DL0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPRIISRSPK MPQSRYTAGV PADGKISPGV IRVIVKTPGN QIIFTVADDT
60 70 80 90 100
LVRQFKEILS AHFKCQMEQL VLVFMGRLLK DHDTLSQRGI TDGHIIHVVI
110 120 130 140 150
KSKHGPRSLA HSFRNLVTNN PCHQDRNPKG NSSMVCQSAG MNETKVESSL
160 170 180 190 200
LMEPEAPKVG TESPEVGSLE HIAQVLENLC VQSLLSNMDF VHQMPPEQPY
210 220 230 240 250
MEELIQQNPE VSHLLDNSEI LCQTLELVRH LAIIQEIMQI QQPAQNPEYP
260 270 280 290 300
PNSQPFLGLE TVPNGNNHLG QSYVNNNDHM LNGVPDLLEG NCFTALLDEQ
310 320 330 340 350
VLEQVQTPSL SQPLPQEQWD QLSSSQVIYA NSCGLSSITP TNATPNHTNN
360 370 380 390 400
VSRENPAIVA TQGQSNVCAV QQPAEIPVLP TISINQKPQV DKDTTITLGI
410 420 430 440 450
SDQWLEEDLQ QSDDQTSSQI TGGMIQLLRN HPQMAAQMLL LMNTSQLNEQ
460 470 480 490 500
WRQETPTPLQ SSQLHDLLLA LANPKTSQAL LQIEHGLQLL ATEAPALLPY
510 520 530 540 550
IEPYLWGLGW LIPSICSYPD IVPWTWNVQD MAEPQCPESC HKSETVLQKV
560 570 580 590 600
QPPSGDPSHS LQAPEVRFSK EMECLQAMGF VNYNANLQAL IATDGDTNAA
610
IYKLKSSQGF
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 17 | T → P in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 52 | V → G in BAC36434 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 58 | I → M in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 82 | H → Y in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 132 | S → C in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 142 | N → S in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 145 | K → I in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 150 | Missing in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 163 | S → G in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 196 | P → Q in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 256 | F → Y in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 284 | V → A in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 345 | P → S in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 383 | S → P in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 387 | K → E in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 395 | T → A in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 423 | G → R in AAI13135 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 445 | S → P in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 445 | S → P in AAI13135 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 460 | Q → H in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 517 | S → G in AAI11902 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 522 | V → E in BAC36434 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 553 | P → L in AAI11902 (PubMed:15489334).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK076645 mRNA Translation: BAC36434.1 AC123830 Genomic DNA No translation available. BC111901 mRNA Translation: AAI11902.1 BC113134 mRNA Translation: AAI13135.1 |
CCDSi | CCDS21611.1 |
RefSeqi | NP_941026.2, NM_198624.3 |
Genome annotation databases
Ensembli | ENSMUST00000059121; ENSMUSP00000056365; ENSMUSG00000051437 |
GeneIDi | 244179 |
KEGGi | mmu:244179 |
UCSCi | uc009ivl.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK076645 mRNA Translation: BAC36434.1 AC123830 Genomic DNA No translation available. BC111901 mRNA Translation: AAI11902.1 BC113134 mRNA Translation: AAI13135.1 |
CCDSi | CCDS21611.1 |
RefSeqi | NP_941026.2, NM_198624.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2DNA | NMR | - | A | 557-610 | [»] | |
SMRi | Q14DL0 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000056365 |
PTM databases
iPTMneti | Q14DL0 |
PhosphoSitePlusi | Q14DL0 |
Proteomic databases
PaxDbi | Q14DL0 |
PRIDEi | Q14DL0 |
ProteomicsDBi | 297796 |
Protocols and materials databases
Antibodypediai | 23640, 77 antibodies from 20 providers |
DNASUi | 244179 |
Genome annotation databases
Ensembli | ENSMUST00000059121; ENSMUSP00000056365; ENSMUSG00000051437 |
GeneIDi | 244179 |
KEGGi | mmu:244179 |
UCSCi | uc009ivl.1, mouse |
Organism-specific databases
CTDi | 143630 |
MGIi | MGI:2685336, Ubqlnl |
VEuPathDBi | HostDB:ENSMUSG00000051437 |
Phylogenomic databases
eggNOGi | KOG0010, Eukaryota |
GeneTreei | ENSGT00940000163345 |
HOGENOMi | CLU_024293_4_0_1 |
InParanoidi | Q14DL0 |
OMAi | MLFMSMP |
OrthoDBi | 1553668at2759 |
PhylomeDBi | Q14DL0 |
TreeFami | TF314412 |
Miscellaneous databases
BioGRID-ORCSi | 244179, 1 hit in 64 CRISPR screens |
EvolutionaryTracei | Q14DL0 |
PROi | PR:Q14DL0 |
RNActi | Q14DL0, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000051437, Expressed in testis and 28 other tissues |
Genevisiblei | Q14DL0, MM |
Family and domain databases
InterProi | View protein in InterPro IPR009060, UBA-like_sf IPR000626, Ubiquitin-like_dom IPR029071, Ubiquitin-like_domsf |
Pfami | View protein in Pfam PF00240, ubiquitin, 1 hit |
SMARTi | View protein in SMART SM00213, UBQ, 1 hit |
SUPFAMi | SSF46934, SSF46934, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS50053, UBIQUITIN_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | UBQLN_MOUSE | |
Accessioni | Q14DL0Primary (citable) accession number: Q14DL0 Secondary accession number(s): E9QM12, Q14DR8, Q8BVT0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 23, 2007 |
Last sequence update: | July 27, 2011 | |
Last modified: | February 23, 2022 | |
This is version 98 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references