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Protein

Testis-expressed protein 35

Gene

Tex35

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed protein 35
Alternative name(s):
Testis-specific conserved protein of 24 kDa
Gene namesi
Name:Tex35
Synonyms:Tsc24
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1920685 Tex35

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002511881 – 207Testis-expressed protein 35Add BLAST207

Proteomic databases

PaxDbiQ14BK3
PRIDEiQ14BK3

PTM databases

iPTMnetiQ14BK3
PhosphoSitePlusiQ14BK3

Expressioni

Tissue specificityi

Testis-specific. Expressed during spermatogenesis.1 Publication

Gene expression databases

CleanExiMM_1700057K13RIK

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000114092

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili43 – 79Sequence analysisAdd BLAST37

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IZ1Y Eukaryota
ENOG411197W LUCA
HOGENOMiHOG000111219
HOVERGENiHBG058182
InParanoidiQ14BK3
PhylomeDBiQ14BK3
TreeFamiTF337831

Family and domain databases

InterProiView protein in InterPro
IPR027874 Tex35
PANTHERiPTHR36860 PTHR36860, 1 hit
PfamiView protein in Pfam
PF15079 Tsc35, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q14BK3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSAKNAELKK TNLKKNYKAV CMEPKLTQIY DFKGFKQEGL LIRKGMTREL
60 70 80 90 100
KNELREVREQ LTEKMEEIKQ IKDIMDKDFD KLYEFVEIMK EMQQDMDEKM
110 120 130 140 150
DVLINNQKNN KLPFQNQAKE QQKFWQLGKM DKSSQAMITE EPDGVPLACD
160 170 180 190 200
KNVVPPKPTR NPLESLHPCQ SCCEKCLLCA LKTNRNQGRP SHHAWVPFSP

LSSGAAF
Length:207
Mass (Da):24,056
Last modified:August 22, 2006 - v1
Checksum:i82D9E68B4109E952
GO
Isoform 2 (identifier: Q14BK3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     188-188: G → GR

Note: No experimental confirmation available.
Show »
Length:208
Mass (Da):24,212
Checksum:i639AA50C49D7DE04
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WNR4A0A087WNR4_MOUSE
Testis-expressed protein 35
Tex35
209Annotation score:
D3Z652D3Z652_MOUSE
Testis-expressed protein 35
Tex35 1700057K13Rik
186Annotation score:
D3Z4U7D3Z4U7_MOUSE
Testis-expressed protein 35
Tex35 1700057K13Rik
187Annotation score:
A0A0R4J1P6A0A0R4J1P6_MOUSE
Testis-expressed protein 35
Tex35
208Annotation score:
A0A0R4J070A0A0R4J070_MOUSE
Testis-expressed protein 35
Tex35
207Annotation score:
D6RGU0D6RGU0_MOUSE
Testis-expressed protein 35
Tex35 1700057K13Rik
55Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti133S → G in BAB24758 (PubMed:16141072).Curated1
Sequence conflicti133S → G in AAH99580 (PubMed:15489334).Curated1
Sequence conflicti145V → A in BAB24758 (PubMed:16141072).Curated1
Sequence conflicti145V → A in AAH99580 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_020742188G → GR in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK006825 mRNA Translation: BAB24758.1
BC099580 mRNA Translation: AAH99580.1
BC115790 mRNA Translation: AAI15791.1
CCDSiCCDS48407.1 [Q14BK3-2]
CCDS78718.1 [Q14BK3-1]
RefSeqiNP_001291988.1, NM_001305059.1
NP_001291990.1, NM_001305061.1
NP_001291991.1, NM_001305062.1
NP_001291992.1, NM_001305063.1
NP_082816.1, NM_028540.3
UniGeneiMm.116705

Genome annotation databases

GeneIDi73435
KEGGimmu:73435

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK006825 mRNA Translation: BAB24758.1
BC099580 mRNA Translation: AAH99580.1
BC115790 mRNA Translation: AAI15791.1
CCDSiCCDS48407.1 [Q14BK3-2]
CCDS78718.1 [Q14BK3-1]
RefSeqiNP_001291988.1, NM_001305059.1
NP_001291990.1, NM_001305061.1
NP_001291991.1, NM_001305062.1
NP_001291992.1, NM_001305063.1
NP_082816.1, NM_028540.3
UniGeneiMm.116705

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000114092

PTM databases

iPTMnetiQ14BK3
PhosphoSitePlusiQ14BK3

Proteomic databases

PaxDbiQ14BK3
PRIDEiQ14BK3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi73435
KEGGimmu:73435

Organism-specific databases

CTDi84066
MGIiMGI:1920685 Tex35

Phylogenomic databases

eggNOGiENOG410IZ1Y Eukaryota
ENOG411197W LUCA
HOGENOMiHOG000111219
HOVERGENiHBG058182
InParanoidiQ14BK3
PhylomeDBiQ14BK3
TreeFamiTF337831

Miscellaneous databases

PROiPR:Q14BK3
SOURCEiSearch...

Gene expression databases

CleanExiMM_1700057K13RIK

Family and domain databases

InterProiView protein in InterPro
IPR027874 Tex35
PANTHERiPTHR36860 PTHR36860, 1 hit
PfamiView protein in Pfam
PF15079 Tsc35, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTEX35_MOUSE
AccessioniPrimary (citable) accession number: Q14BK3
Secondary accession number(s): Q4KKY9, Q9D9J9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: August 22, 2006
Last modified: November 22, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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