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Entry version 104 (02 Jun 2021)
Sequence version 2 (29 May 2007)
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Protein

Anoctamin-7

Gene

Ano7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (PubMed:23532839).

Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:23532839).

May play a role in cell-cell interactions (By similarity).

By similarity1 Publication

Miscellaneous

The term 'anoctamin' was coined because these channels are anion selective and have eight (OCT) transmembrane segments. There is some dissatisfaction in the field with the Ano nomenclature because it is not certain that all the members of this family are anion channels or have the 8-transmembrane topology.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-2672351, Stimuli-sensing channels

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...
SwissLipidsi
SLP:000000375

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Anoctamin-7
Alternative name(s):
New gene expressed in prostate homolog
Transmembrane protein 16G
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ano7
Synonyms:Ngep, Tmem16g
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3052714, Ano7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 297CytoplasmicSequence analysisAdd BLAST297
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei298 – 318HelicalSequence analysisAdd BLAST21
Topological domaini319 – 362ExtracellularSequence analysisAdd BLAST44
Transmembranei363 – 383HelicalSequence analysisAdd BLAST21
Topological domaini384 – 441CytoplasmicSequence analysisAdd BLAST58
Transmembranei442 – 462HelicalSequence analysisAdd BLAST21
Topological domaini463 – 492ExtracellularSequence analysisAdd BLAST30
Transmembranei493 – 513HelicalSequence analysisAdd BLAST21
Topological domaini514 – 530CytoplasmicSequence analysisAdd BLAST17
Transmembranei531 – 551HelicalSequence analysisAdd BLAST21
Topological domaini552 – 651ExtracellularSequence analysisAdd BLAST100
Transmembranei652 – 672HelicalSequence analysisAdd BLAST21
Topological domaini673 – 700CytoplasmicSequence analysisAdd BLAST28
Transmembranei701 – 721HelicalSequence analysisAdd BLAST21
Topological domaini722 – 780ExtracellularSequence analysisAdd BLAST59
Transmembranei781 – 801HelicalSequence analysisAdd BLAST21
Topological domaini802 – 859CytoplasmicSequence analysisAdd BLAST58

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002893271 – 859Anoctamin-7Add BLAST859

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi746N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi761N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q14AT5

PRoteomics IDEntifications database

More...
PRIDEi
Q14AT5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
296311 [Q14AT5-1]
296312 [Q14AT5-2]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q14AT5, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q14AT5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q14AT5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in the stomach. Expressed at low levels in small intestine and large intestine.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000034107, Expressed in stomach and 63 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
240364, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000140438

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q14AT5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q14AT5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni25 – 50DisorderedSequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi25 – 47Polar residuesSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the anoctamin family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2514, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158551

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006685_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q14AT5

Identification of Orthologs from Complete Genome Data

More...
OMAi
GLYCQDQ

Database of Orthologous Groups

More...
OrthoDBi
1263362at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q14AT5

TreeFam database of animal gene trees

More...
TreeFami
TF314265

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032394, Anoct_dimer
IPR007632, Anoctamin
IPR031296, Anoctamin-7

The PANTHER Classification System

More...
PANTHERi
PTHR12308, PTHR12308, 1 hit
PTHR12308:SF22, PTHR12308:SF22, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16178, Anoct_dimer, 1 hit
PF04547, Anoctamin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q14AT5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLRGQAREED SVVLIDMASP EAGNGCSYGS TAQASEAGKQ QVAPSRVGSS
60 70 80 90 100
AKPPIDFVLV WEEDLRNQEN PTKDKTDTHE VWRETFLENL CLAGLKIDQH
110 120 130 140 150
DVQDEAAAVH YILLRAPWAV LCYYAEDLRL KLPLQELPNQ ASNWSATLLE
160 170 180 190 200
WLGIPNILLE HVPDTPPEYY SCQFKASKLQ WFLGSDNQDT FFTSTKRHQI
210 220 230 240 250
LFEILAKTPY GHEKKGLFGI DQLLAEGVFS AAFPLHDGPF SAVPESSQVL
260 270 280 290 300
GLIQRQVLFQ HWARWGKWNK YQPLDHVRRY FGEKVALYFA WLGFYTGWLL
310 320 330 340 350
PAAVVGTVVF LVGCFLVFSD IPTQELCHSS DSFDMCPLCS DCSFWLLSSA
360 370 380 390 400
CTLAQAGRLF DHGGTVFFSL FMALWAVLLL EYWKRKNATL AYRWDCSDYE
410 420 430 440 450
DIEERPRPQF AATAPMTALN PITGEDEPYF PEKNRVRRML AGSVVLLMMV
460 470 480 490 500
AVVIMCLVSV ILYRAVMAII VSRSDNAFLS AWASRIASLT GSVVNLVFIL
510 520 530 540 550
ILSKVYVLLA QVLTRWEMHR TQTEFEDAFT LKVFIFQFVN FYASPVYIAF
560 570 580 590 600
FKGRFVGYPG NYHTLFGIRN EECPAGGCLS ELAQELLVIM VGKQIINNVQ
610 620 630 640 650
EVLVPKLKGC WQKFSRGKKA GTGTHPAPWE ADYELLPCEG LFHEYLEMVL
660 670 680 690 700
QFGFVTIFVA ACPLAPLFAL LNNWVEIRLD ARKFVCEYRR PVAERAQDIG
710 720 730 740 750
IWFHILTGLT HLAVISNAFL LAFSSDFLPR VYYSWTHAPD LHGFLNFTLA
760 770 780 790 800
RAPPTFTSAH NRTCRYRAFR DDDGHYSPTY WTLLAIRLAF VIVFEHVVFS
810 820 830 840 850
IGRVLDLLVP DIPESVEIKV KREYYLAKQA LAENEALLGA TGVKDDQPPS

SEPSLGLPA
Length:859
Mass (Da):97,128
Last modified:May 29, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i82E1A473C59C8DA3
GO
Isoform 2 (identifier: Q14AT5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     836-843: ALLGATGV → VTVGVTGG
     844-859: Missing.

Show »
Length:843
Mass (Da):95,496
Checksum:i7E28834A94251748
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WPD8A0A087WPD8_MOUSE
Anoctamin-7
Ano7
69Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_026009836 – 843ALLGATGV → VTVGVTGG in isoform 2. 1 Publication8
Alternative sequenceiVSP_026010844 – 859Missing in isoform 2. 1 PublicationAdd BLAST16

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC108412 Genomic DNA No translation available.
AC124669 Genomic DNA No translation available.
BC116706 mRNA Translation: AAI16707.1
BK004075 mRNA Translation: DAA04566.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS15188.1 [Q14AT5-1]
CCDS78656.1 [Q14AT5-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001258813.1, NM_001271884.1 [Q14AT5-2]
NP_996914.1, NM_207031.2 [Q14AT5-1]
XP_006529796.1, XM_006529733.2 [Q14AT5-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000058682; ENSMUSP00000050495; ENSMUSG00000034107 [Q14AT5-2]
ENSMUST00000186641; ENSMUSP00000140438; ENSMUSG00000034107 [Q14AT5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
404545

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:404545

UCSC genome browser

More...
UCSCi
uc007cdw.2, mouse [Q14AT5-1]
uc033fku.1, mouse [Q14AT5-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108412 Genomic DNA No translation available.
AC124669 Genomic DNA No translation available.
BC116706 mRNA Translation: AAI16707.1
BK004075 mRNA Translation: DAA04566.1
CCDSiCCDS15188.1 [Q14AT5-1]
CCDS78656.1 [Q14AT5-2]
RefSeqiNP_001258813.1, NM_001271884.1 [Q14AT5-2]
NP_996914.1, NM_207031.2 [Q14AT5-1]
XP_006529796.1, XM_006529733.2 [Q14AT5-1]

3D structure databases

SMRiQ14AT5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi240364, 3 interactors
STRINGi10090.ENSMUSP00000140438

Chemistry databases

SwissLipidsiSLP:000000375

PTM databases

GlyGeniQ14AT5, 2 sites
iPTMnetiQ14AT5
PhosphoSitePlusiQ14AT5

Proteomic databases

PaxDbiQ14AT5
PRIDEiQ14AT5
ProteomicsDBi296311 [Q14AT5-1]
296312 [Q14AT5-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
47723, 117 antibodies

The DNASU plasmid repository

More...
DNASUi
404545

Genome annotation databases

EnsembliENSMUST00000058682; ENSMUSP00000050495; ENSMUSG00000034107 [Q14AT5-2]
ENSMUST00000186641; ENSMUSP00000140438; ENSMUSG00000034107 [Q14AT5-1]
GeneIDi404545
KEGGimmu:404545
UCSCiuc007cdw.2, mouse [Q14AT5-1]
uc033fku.1, mouse [Q14AT5-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
50636
MGIiMGI:3052714, Ano7

Phylogenomic databases

eggNOGiKOG2514, Eukaryota
GeneTreeiENSGT00940000158551
HOGENOMiCLU_006685_0_1_1
InParanoidiQ14AT5
OMAiGLYCQDQ
OrthoDBi1263362at2759
PhylomeDBiQ14AT5
TreeFamiTF314265

Enzyme and pathway databases

ReactomeiR-MMU-2672351, Stimuli-sensing channels

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
404545, 2 hits in 52 CRISPR screens

Protein Ontology

More...
PROi
PR:Q14AT5
RNActiQ14AT5, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000034107, Expressed in stomach and 63 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR032394, Anoct_dimer
IPR007632, Anoctamin
IPR031296, Anoctamin-7
PANTHERiPTHR12308, PTHR12308, 1 hit
PTHR12308:SF22, PTHR12308:SF22, 1 hit
PfamiView protein in Pfam
PF16178, Anoct_dimer, 1 hit
PF04547, Anoctamin, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiANO7_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q14AT5
Secondary accession number(s): Q6IFT5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: June 2, 2021
This is version 104 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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