UniProtKB - Q14AJ9 (Q14AJ9_MOUSE)
Protein
Olfactory receptor
Gene
Olfr125
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- G protein-coupled receptor activity Source: UniProtKB-KW
- odorant binding Source: GO_Central
- olfactory receptor activity Source: MGI
GO - Biological processi
- G protein-coupled receptor signaling pathway Source: MGI
- sensory perception of smell Source: MGI
Keywordsi
Molecular function | G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer |
Biological process | OlfactionUniRule annotationSAAS annotation, Sensory transduction |
Enzyme and pathway databases
Reactomei | R-MMU-381753 Olfactory Signaling Pathway |
Names & Taxonomyi
Protein namesi | Recommended name: Olfactory receptorUniRule annotation |
Gene namesi | Name:Olfr125Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2177508 Olfr125 |
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotationSAAS annotation; Multi-pass membrane protein UniRule annotationSAAS annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: MGI
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 20 – 46 | HelicalUniRule annotationAdd BLAST | 27 | |
Transmembranei | 58 – 75 | HelicalUniRule annotationAdd BLAST | 18 | |
Transmembranei | 95 – 115 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 136 – 155 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 190 – 213 | HelicalUniRule annotationAdd BLAST | 24 | |
Transmembranei | 234 – 257 | HelicalUniRule annotationAdd BLAST | 24 | |
Transmembranei | 269 – 289 | HelicalUniRule annotationAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membraneUniRule annotationSAAS annotation, MembraneExpressioni
Gene expression databases
Bgeei | ENSMUSG00000050613 Expressed in 3 organ(s), highest expression level in olfactory epithelium |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 38 – 287 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 250 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationSAAS annotationPhylogenomic databases
eggNOGi | ENOG410IEM2 Eukaryota ENOG410YBQN LUCA |
GeneTreei | ENSGT00940000153133 |
HOGENOMi | HOG000041365 |
HOVERGENi | HBG017625 |
KOi | K04257 |
OMAi | FSIPLCG |
OrthoDBi | 876979at2759 |
TreeFami | TF352740 |
Family and domain databases
InterProi | View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000725 Olfact_rcpt |
Pfami | View protein in Pfam PF13853 7tm_4, 1 hit |
PRINTSi | PR00237 GPCRRHODOPSN PR00245 OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q14AJ9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNVSFKTGFL LMGFSDERNL QILHSVLFLI TYLLAIMGNL LIITIITLDQ
60 70 80 90 100
RLHSPMYYFL KHLSFLDLCF ISVTVPQSIA NSLMDNGFIS LGQCMLQVFF
110 120 130 140 150
FIALASSEVA ILTVMSYDRY VAICRPLQYE TIMDPHACKC AVIAVWMAGG
160 170 180 190 200
LSGLLHTGVN FSIPLCGKRI IHQFFCDIPQ MLKLACSYEF INEIAVAAFT
210 220 230 240 250
TSTAFVCLIA IVFSYTQIFS TVMRIPSADS RTKVFSTCLP HLFVVMFFLS
260 270 280 290 300
AAGFEFLRPP SDSLSAMDLI FSIFYTVIPP TLNPLIYSLR NEAMKAALRK
310 320
VLSKEEFSRR MVYVKAIFNL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR974430 Genomic DNA No translation available. BC116810 mRNA Translation: AAI16811.1 BC116812 mRNA Translation: AAI16813.1 |
RefSeqi | NP_666402.2, NM_146290.2 |
UniGenei | Mm.377416 |
Genome annotation databases
Ensembli | ENSMUST00000050255; ENSMUSP00000055221; ENSMUSG00000050613 ENSMUST00000213857; ENSMUSP00000149602; ENSMUSG00000050613 |
GeneIDi | 258287 |
KEGGi | mmu:258287 |
UCSCi | uc008cnq.2 mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR974430 Genomic DNA No translation available. BC116810 mRNA Translation: AAI16811.1 BC116812 mRNA Translation: AAI16813.1 |
RefSeqi | NP_666402.2, NM_146290.2 |
UniGenei | Mm.377416 |
3D structure databases
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000055221 |
Protein family/group databases
GPCRDBi | Search... |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
Ensembli | ENSMUST00000050255; ENSMUSP00000055221; ENSMUSG00000050613 ENSMUST00000213857; ENSMUSP00000149602; ENSMUSG00000050613 |
GeneIDi | 258287 |
KEGGi | mmu:258287 |
UCSCi | uc008cnq.2 mouse |
Organism-specific databases
CTDi | 258287 |
MGIi | MGI:2177508 Olfr125 |
Phylogenomic databases
eggNOGi | ENOG410IEM2 Eukaryota ENOG410YBQN LUCA |
GeneTreei | ENSGT00940000153133 |
HOGENOMi | HOG000041365 |
HOVERGENi | HBG017625 |
KOi | K04257 |
OMAi | FSIPLCG |
OrthoDBi | 876979at2759 |
TreeFami | TF352740 |
Enzyme and pathway databases
Reactomei | R-MMU-381753 Olfactory Signaling Pathway |
Miscellaneous databases
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000050613 Expressed in 3 organ(s), highest expression level in olfactory epithelium |
Family and domain databases
InterProi | View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000725 Olfact_rcpt |
Pfami | View protein in Pfam PF13853 7tm_4, 1 hit |
PRINTSi | PR00237 GPCRRHODOPSN PR00245 OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | Q14AJ9_MOUSE | |
Accessioni | Q14AJ9Primary (citable) accession number: Q14AJ9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 22, 2006 |
Last sequence update: | August 22, 2006 | |
Last modified: | January 16, 2019 | |
This is version 111 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |