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Protein

Collagen alpha-1(XIX) chain

Gene

COL19A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • extracellular matrix structural constituent Source: GO_Central
  • protein binding, bridging Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processCell adhesion, Differentiation, Myogenesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-1442490 Collagen degradation
R-HSA-1650814 Collagen biosynthesis and modifying enzymes
R-HSA-8948216 Collagen chain trimerization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Collagen alpha-1(XIX) chain
Alternative name(s):
Collagen alpha-1(Y) chain
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COL19A1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000082293.12

Human Gene Nomenclature Database

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HGNCi
HGNC:2196 COL19A1

Online Mendelian Inheritance in Man (OMIM)

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MIMi
120165 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q14993

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
1310

Open Targets

More...
OpenTargetsi
ENSG00000082293

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA26712

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
COL19A1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
68840003

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000579724 – 1142Collagen alpha-1(XIX) chainAdd BLAST1119

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.

Keywords - PTMi

Disulfide bond, Hydroxylation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q14993

PeptideAtlas

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PeptideAtlasi
Q14993

PRoteomics IDEntifications database

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PRIDEi
Q14993

ProteomicsDB human proteome resource

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ProteomicsDBi
60277

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q14993

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q14993

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000082293 Expressed in 75 organ(s), highest expression level in stomach

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q14993 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q14993 HS

Organism-specific databases

Human Protein Atlas

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HPAi
HPA042422

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Oligomer; disulfide-linked.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
107705, 1 interactor

ComplexPortal: manually curated resource of macromolecular complexes

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ComplexPortali
CPX-1760 Collagen type XIX trimer

STRING: functional protein association networks

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STRINGi
9606.ENSP00000316030

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q14993

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q14993

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini50 – 234Laminin G-likeAdd BLAST185
Domaini292 – 349Collagen-like 1Add BLAST58
Domaini350 – 391Collagen-like 2Add BLAST42
Domaini392 – 433Collagen-like 3Add BLAST42
Domaini474 – 516Collagen-like 4Add BLAST43
Domaini568 – 624Collagen-like 5Add BLAST57
Domaini626 – 678Collagen-like 6Add BLAST53
Domaini728 – 778Collagen-like 7Add BLAST51
Domaini779 – 814Collagen-like 8Add BLAST36
Domaini845 – 903Collagen-like 9Add BLAST59
Domaini904 – 947Collagen-like 10Add BLAST44
Domaini948 – 1004Collagen-like 11Add BLAST57

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni292 – 351Triple-helical region 1 (COL1)Add BLAST60
Regioni370 – 429Triple-helical region 2 (COL2)Add BLAST60
Regioni448 – 688Triple-helical region 3 (COL3)Add BLAST241
Regioni700 – 818Triple-helical region 4 (COL4)Add BLAST119
Regioni833 – 1012Triple-helical region 5 (COL5)Add BLAST180
Regioni1054 – 1111Triple-helical region 6 (COL6)Add BLAST58

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi952 – 954Cell attachment siteSequence analysis3

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The numerous interruptions in the triple helix may make this molecule either elastic or flexible.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Collagen, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3544 Eukaryota
ENOG410YG60 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000158276

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG060240

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q14993

Identification of Orthologs from Complete Genome Data

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OMAi
ISLYMDC

Database of Orthologous Groups

More...
OrthoDBi
EOG091G02GL

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q14993

TreeFam database of animal gene trees

More...
TreeFami
TF351778

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR001791 Laminin_G

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01391 Collagen, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00210 TSPN, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF49899 SSF49899, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q14993-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLTGPWKLW LWMSIFLLPA STSVTVRDKT EESCPILRIE GHQLTYDNIN
60 70 80 90 100
KLEVSGFDLG DSFSLRRAFC ESDKTCFKLG SALLIRDTIK IFPKGLPEEY
110 120 130 140 150
SVAAMFRVRR NAKKERWFLW QVLNQQNIPQ ISIVVDGGKK VVEFMFQATE
160 170 180 190 200
GDVLNYIFRN RELRPLFDRQ WHKLGISIQS QVISLYMDCN LIARRQTDEK
210 220 230 240 250
DTVDFHGRTV IATRASDGKP VDIELHQLKI YCSANLIAQE TCCEISDTKC
260 270 280 290 300
PEQDGFGNIA SSWVTAHASK MSSYLPAKQE LKDQCQCIPN KGEAGLPGAP
310 320 330 340 350
GSPGQKGHKG EPGENGLHGA PGFPGQKGEQ GFEGSKGETG EKGEQGEKGD
360 370 380 390 400
PALAGLNGEN GLKGDLGPHG PPGPKGEKGD TGPPGPPALP GSLGIQGPQG
410 420 430 440 450
PPGKEGQRGR RGKTGPPGKP GPPGPPGPPG IQGIHQTLGG YYNKDNKGND
460 470 480 490 500
EHEAGGLKGD KGETGLPGFP GSVGPKGQKG EPGEPFTKGE KGDRGEPGVI
510 520 530 540 550
GSQGVKGEPG DPGPPGLIGS PGLKGQQGSA GSMGPRGPPG DVGLPGEHGI
560 570 580 590 600
PGKQGIKGEK GDPGGIIGPP GLPGPKGEAG PPGKSLPGEP GLDGNPGAPG
610 620 630 640 650
PRGPKGERGL PGVHGSPGDI GPQGIGIPGR TGAQGPAGEP GIQGPRGLPG
660 670 680 690 700
LPGTPGTPGN DGVPGRDGKP GLPGPPGDPI ALPLLGDIGA LLKNFCGNCQ
710 720 730 740 750
ASVPGLKSNK GEEGGAGEPG KYDSMARKGD IGPRGPPGIP GREGPKGSKG
760 770 780 790 800
ERGYPGIPGE KGDEGLQGIP GIPGAPGPTG PPGLMGRTGH PGPTGAKGEK
810 820 830 840 850
GSDGPPGKPG PPGPPGIPFN ERNGMSSLYK IKGGVNVPSY PGPPGPPGPK
860 870 880 890 900
GDPGPVGEPG AMGLPGLEGF PGVKGDRGPA GPPGIAGMSG KPGAPGPPGV
910 920 930 940 950
PGEPGERGPV GDIGFPGPEG PSGKPGINGK DGIPGAQGIM GKPGDRGPKG
960 970 980 990 1000
ERGDQGIPGD RGSQGERGKP GLTGMKGAIG PMGPPGNKGS MGSPGHQGPP
1010 1020 1030 1040 1050
GSPGIPGIPA DAVSFEEIKK YINQEVLRIF EERMAVFLSQ LKLPAAMLAA
1060 1070 1080 1090 1100
QAYGRPGPPG KDGLPGPPGD PGPQGYRGQK GERGEPGIGL PGSPGLPGTS
1110 1120 1130 1140
ALGLPGSPGA PGPQGPPGPS GRCNPEDCLY PVSHAHQRTG GN
Length:1,142
Mass (Da):115,221
Last modified:July 5, 2005 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF1153CE751387943
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WVJ7A0A087WVJ7_HUMAN
Collagen alpha-1(XIX) chain
COL19A1
60Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5JVU1Q5JVU1_HUMAN
Collagen alpha-1(XIX) chain
COL19A1
36Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti89I → MY in BAA23309 (PubMed:9344653).Curated1
Sequence conflicti106 – 119FRVRR…ERWFL → ETTVPFWRFFVLET in AAA36358 (PubMed:7916703).CuratedAdd BLAST14
Sequence conflicti279Q → L in BAA07368 (PubMed:7775380).Curated1
Sequence conflicti354 – 355AG → GC in AAA58468 (PubMed:1639419).Curated2
Sequence conflicti365D → V in BAA07368 (PubMed:7775380).Curated1
Sequence conflicti365D → V in AAA58468 (PubMed:1639419).Curated1
Sequence conflicti441 – 442YY → DD in BAA07368 (PubMed:7775380).Curated2
Sequence conflicti441 – 442YY → DD in AAA58468 (PubMed:1639419).Curated2
Sequence conflicti622 – 624PQG → QRD in AAA58468 (PubMed:1639419).Curated3
Sequence conflicti816 – 823GIPFNERN → VSCSRLKI in AAA36358 (PubMed:7916703).Curated8
Sequence conflicti937Q → E in BAA07368 (PubMed:7775380).Curated1
Sequence conflicti1140G → C in BAA23309 (PubMed:9344653).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024419352A → G. Corresponds to variant dbSNP:rs2273426Ensembl.1
Natural variantiVAR_035746361G → D in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_048782406G → E. Corresponds to variant dbSNP:rs13204209Ensembl.1
Natural variantiVAR_048783496E → G. Corresponds to variant dbSNP:rs13204209Ensembl.1
Natural variantiVAR_0357471019K → N in a breast cancer sample; somatic mutation. 1 PublicationCorresponds to variant dbSNP:rs771562232Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D38163 mRNA Translation: BAA07368.1
AB004629 Genomic DNA Translation: BAA23309.1
AL118519 Genomic DNA No translation available.
AL133388 Genomic DNA No translation available.
AL136445 Genomic DNA No translation available.
AL160262 Genomic DNA No translation available.
AL359539 Genomic DNA No translation available.
BC113362 mRNA Translation: AAI13363.1
BC113364 mRNA Translation: AAI13365.1
M63597 mRNA Translation: AAA58468.1
L12347 mRNA Translation: AAA36358.1
U09279 mRNA Translation: AAA21146.1
AH000850 Genomic DNA Translation: AAA21147.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS4970.1

Protein sequence database of the Protein Information Resource

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PIRi
JX0369

NCBI Reference Sequences

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RefSeqi
NP_001849.2, NM_001858.5
XP_011533740.1, XM_011535438.2
XP_016865744.1, XM_017010255.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.444842

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000620364; ENSP00000480474; ENSG00000082293

Database of genes from NCBI RefSeq genomes

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GeneIDi
1310

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:1310

UCSC genome browser

More...
UCSCi
uc032xam.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38163 mRNA Translation: BAA07368.1
AB004629 Genomic DNA Translation: BAA23309.1
AL118519 Genomic DNA No translation available.
AL133388 Genomic DNA No translation available.
AL136445 Genomic DNA No translation available.
AL160262 Genomic DNA No translation available.
AL359539 Genomic DNA No translation available.
BC113362 mRNA Translation: AAI13363.1
BC113364 mRNA Translation: AAI13365.1
M63597 mRNA Translation: AAA58468.1
L12347 mRNA Translation: AAA36358.1
U09279 mRNA Translation: AAA21146.1
AH000850 Genomic DNA Translation: AAA21147.1
CCDSiCCDS4970.1
PIRiJX0369
RefSeqiNP_001849.2, NM_001858.5
XP_011533740.1, XM_011535438.2
XP_016865744.1, XM_017010255.1
UniGeneiHs.444842

3D structure databases

ProteinModelPortaliQ14993
SMRiQ14993
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi107705, 1 interactor
ComplexPortaliCPX-1760 Collagen type XIX trimer
STRINGi9606.ENSP00000316030

PTM databases

iPTMnetiQ14993
PhosphoSitePlusiQ14993

Polymorphism and mutation databases

BioMutaiCOL19A1
DMDMi68840003

Proteomic databases

PaxDbiQ14993
PeptideAtlasiQ14993
PRIDEiQ14993
ProteomicsDBi60277

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000620364; ENSP00000480474; ENSG00000082293
GeneIDi1310
KEGGihsa:1310
UCSCiuc032xam.2 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
1310
DisGeNETi1310
EuPathDBiHostDB:ENSG00000082293.12

GeneCards: human genes, protein and diseases

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GeneCardsi
COL19A1
HGNCiHGNC:2196 COL19A1
HPAiHPA042422
MIMi120165 gene
neXtProtiNX_Q14993
OpenTargetsiENSG00000082293
PharmGKBiPA26712

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3544 Eukaryota
ENOG410YG60 LUCA
GeneTreeiENSGT00940000158276
HOVERGENiHBG060240
InParanoidiQ14993
OMAiISLYMDC
OrthoDBiEOG091G02GL
PhylomeDBiQ14993
TreeFamiTF351778

Enzyme and pathway databases

ReactomeiR-HSA-1442490 Collagen degradation
R-HSA-1650814 Collagen biosynthesis and modifying enzymes
R-HSA-8948216 Collagen chain trimerization

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
COL19A1 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
Collagen,_type_XIX,_alpha_1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
1310

Protein Ontology

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PROi
PR:Q14993

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000082293 Expressed in 75 organ(s), highest expression level in stomach
ExpressionAtlasiQ14993 baseline and differential
GenevisibleiQ14993 HS

Family and domain databases

InterProiView protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR001791 Laminin_G
PfamiView protein in Pfam
PF01391 Collagen, 10 hits
SMARTiView protein in SMART
SM00210 TSPN, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCOJA1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q14993
Secondary accession number(s): Q00559
, Q05850, Q12885, Q13676, Q14DH1, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: July 5, 2005
Last modified: December 5, 2018
This is version 167 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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