UniProtKB - Q14899 (Q14899_HUMAN)
Protein
Submitted name:
Myc proto-oncogene protein
Gene
MYC
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- eukaryotic initiation factor eIF2 binding Source: UniProtKB
- mRNA binding Source: UniProtKB
GO - Biological processi
- positive regulation of translation Source: UniProtKB
Names & Taxonomyi
Protein namesi | Submitted name: Myc proto-oncogene proteinImportedSubmitted name: Myc-related translation/localization regulatory factorImportedSubmitted name: ORF 114Imported |
Gene namesi | |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:7553, MYC |
Subcellular locationi
Endoplasmic reticulum
- rough endoplasmic reticulum Source: UniProtKB
Nucleus
- nuclear envelope Source: UniProtKB
- nucleoplasmic reticulum Source: UniProtKB
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 6 – 25 | HelicalSequence analysisAdd BLAST | 20 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000155285 |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
Q14899-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRCWVILIIL GIVFLLMPLS FLPIYTNIPR SERAPINTLL SSTLPGTLDQ
60 70 80 90 100
SAALSPALAR RPAAWYARGV AVGAQCVLGV EGSCSACDDL YSQDKDAVCQ
110
TVLLRRSSRE RERV
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP01106 | MYC_HUMAN | Myc proto-oncogene protein | MYC BHLHE39 | 439 | Annotation score: | ||
A0A087WUS5 | A0A087WUS5_HUMAN | Myc proto-oncogene protein | MYC | 454 | Annotation score: | ||
H0YBT0 | H0YBT0_HUMAN | Myc proto-oncogene protein | MYC | 453 | Annotation score: | ||
A0A494C1T8 | A0A494C1T8_HUMAN | Myc proto-oncogene protein | MYC | 339 | Annotation score: | ||
A0A0B4J1R1 | A0A0B4J1R1_HUMAN | Myc proto-oncogene protein | MYC hCG_15917 | 257 | Annotation score: | ||
Q16591 | Q16591_HUMAN | Myc protein | MYC | 188 | Annotation score: | ||
H0YBG3 | H0YBG3_HUMAN | Myc proto-oncogene protein | MYC | 184 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC103819 Genomic DNA No translation available. M13930 mRNA Translation: AAA88093.1 BK006467 mRNA Translation: DAA06340.1 |
Genome annotation databases
Ensembli | ENST00000641252; ENSP00000493139; ENSG00000136997 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC103819 Genomic DNA No translation available. M13930 mRNA Translation: AAA88093.1 BK006467 mRNA Translation: DAA06340.1 |
3D structure databases
SMRi | Q14899 |
ModBasei | Search... |
Proteomic databases
PRIDEi | Q14899 |
Protocols and materials databases
Antibodypediai | 3520, 4059 antibodies |
Genome annotation databases
Ensembli | ENST00000641252; ENSP00000493139; ENSG00000136997 |
Organism-specific databases
HGNCi | HGNC:7553, MYC |
OpenTargetsi | ENSG00000136997 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155285 |
Miscellaneous databases
ChiTaRSi | MYC, human |
Gene expression databases
ExpressionAtlasi | Q14899, baseline and differential |
Family and domain databases
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q14899_HUMAN | |
Accessioni | Q14899Primary (citable) accession number: Q14899 Secondary accession number(s): Q14898 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1996 |
Last sequence update: | November 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 76 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |