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Protein

Cyclin-A2-2

Gene

CYCA2-2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • cell cycle Source: UniProtKB-KW
  • cell division Source: UniProtKB-KW
  • cell proliferation Source: TAIR
  • positive regulation of stomatal complex development Source: TAIR

Keywordsi

Molecular functionCyclin
Biological processCell cycle, Cell division

Enzyme and pathway databases

ReactomeiR-ATH-1538133 G0 and Early G1
R-ATH-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-ATH-5689880 Ub-specific processing proteases
R-ATH-5693607 Processing of DNA double-strand break ends
R-ATH-68911 G2 Phase
R-ATH-68949 Orc1 removal from chromatin
R-ATH-69017 CDK-mediated phosphorylation and removal of Cdc6
R-ATH-69273 Cyclin A/B1/B2 associated events during G2/M transition
R-ATH-69656 Cyclin A:Cdk2-associated events at S phase entry
R-ATH-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-A2-2
Alternative name(s):
Cyc3b-At
Cyclin-3b
G2/mitotic-specific cyclin-A2-2
Short name:
CycA2;2
Gene namesi
Name:CYCA2-2
Synonyms:CYC3B
Ordered Locus Names:At5g11300
ORF Names:F2I11.190
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G11300
TAIRilocus:2148052 AT5G11300

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002869941 – 436Cyclin-A2-2Add BLAST436

Proteomic databases

PaxDbiQ147G5
PRIDEiQ147G5

Expressioni

Tissue specificityi

Expressed in roots, stems, leaves, flowers and siliques.1 Publication

Gene expression databases

ExpressionAtlasiQ147G5 baseline and differential
GenevisibleiQ147G5 AT

Interactioni

Protein-protein interaction databases

BioGridi16279, 15 interactors
IntActiQ147G5, 4 interactors
STRINGi3702.AT5G11300.1

Structurei

3D structure databases

ProteinModelPortaliQ147G5
SMRiQ147G5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family. Cyclin AB subfamily.Curated

Phylogenomic databases

eggNOGiKOG0654 Eukaryota
COG5024 LUCA
HOGENOMiHOG000167672
InParanoidiQ147G5
KOiK06627
OMAiYNQPKFK
OrthoDBiEOG09360C5F
PhylomeDBiQ147G5

Family and domain databases

CDDicd00043 CYCLIN, 2 hits
InterProiView protein in InterPro
IPR039361 Cyclin
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR004367 Cyclin_C-dom
IPR006671 Cyclin_N
PANTHERiPTHR10177 PTHR10177, 2 hits
PfamiView protein in Pfam
PF02984 Cyclin_C, 1 hit
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 2 hits
SM01332 Cyclin_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits
PROSITEiView protein in PROSITE
PS00292 CYCLINS, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q147G5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYCSSSMHPN ANKENISTSD VQESFVRITR SRAKKAMGRG VSIPPTKPSF
60 70 80 90 100
KQQKRRAVLK DVSNTSADII YSELRKGGNI KANRKCLKEP KKAAKEGANS
110 120 130 140 150
AMDILVDMHT EKSKLAEDLS KIRMAEAQDV SLSNFKDEEI TEQQEDGSGV
160 170 180 190 200
MELLQVVDID SNVEDPQCCS LYAADIYDNI HVAELQQRPL ANYMELVQRD
210 220 230 240 250
IDPDMRKILI DWLVEVSDDY KLVPDTLYLT VNLIDRFLSN SYIERQRLQL
260 270 280 290 300
LGVSCMLIAS KYEELSAPGV EEFCFITANT YTRPEVLSME IQILNFVHFR
310 320 330 340 350
LSVPTTKTFL RRFIKAAQAS YKVPFIELEY LANYLAELTL VEYSFLRFLP
360 370 380 390 400
SLIAASAVFL ARWTLDQTDH PWNPTLQHYT RYEVAELKNT VLAMEDLQLN
410 420 430
TSGCTLAATR EKYNQPKFKS VAKLTSPKRV TSLFSR
Length:436
Mass (Da):49,694
Last modified:August 22, 2006 - v1
Checksum:iE8971BD931AA25EF
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8BA04A0A1P8BA04_ARATH
Mitotic-like cyclin 3B from Arabido...
CYC3B CYC2BAT, CYCA2:2, CYCLIN, CYCLIN A2:2, At5g11300
413Annotation score:

Sequence cautioni

The sequence CAB96665 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti284P → R in CAA83277 (PubMed:7972055).Curated1
Sequence conflicti432S → L in CAA83277 (PubMed:7972055).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z31402 mRNA Translation: CAA83277.1
AL360314 Genomic DNA Translation: CAB96665.1 Sequence problems.
CP002688 Genomic DNA Translation: AED91657.1
BT026128 mRNA Translation: ABG48484.1
RefSeqiNP_568248.2, NM_121168.5
UniGeneiAt.1678

Genome annotation databases

EnsemblPlantsiAT5G11300.1; AT5G11300.1; AT5G11300
GeneIDi831001
GrameneiAT5G11300.1; AT5G11300.1; AT5G11300
KEGGiath:AT5G11300

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z31402 mRNA Translation: CAA83277.1
AL360314 Genomic DNA Translation: CAB96665.1 Sequence problems.
CP002688 Genomic DNA Translation: AED91657.1
BT026128 mRNA Translation: ABG48484.1
RefSeqiNP_568248.2, NM_121168.5
UniGeneiAt.1678

3D structure databases

ProteinModelPortaliQ147G5
SMRiQ147G5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi16279, 15 interactors
IntActiQ147G5, 4 interactors
STRINGi3702.AT5G11300.1

Proteomic databases

PaxDbiQ147G5
PRIDEiQ147G5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G11300.1; AT5G11300.1; AT5G11300
GeneIDi831001
GrameneiAT5G11300.1; AT5G11300.1; AT5G11300
KEGGiath:AT5G11300

Organism-specific databases

AraportiAT5G11300
TAIRilocus:2148052 AT5G11300

Phylogenomic databases

eggNOGiKOG0654 Eukaryota
COG5024 LUCA
HOGENOMiHOG000167672
InParanoidiQ147G5
KOiK06627
OMAiYNQPKFK
OrthoDBiEOG09360C5F
PhylomeDBiQ147G5

Enzyme and pathway databases

ReactomeiR-ATH-1538133 G0 and Early G1
R-ATH-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-ATH-5689880 Ub-specific processing proteases
R-ATH-5693607 Processing of DNA double-strand break ends
R-ATH-68911 G2 Phase
R-ATH-68949 Orc1 removal from chromatin
R-ATH-69017 CDK-mediated phosphorylation and removal of Cdc6
R-ATH-69273 Cyclin A/B1/B2 associated events during G2/M transition
R-ATH-69656 Cyclin A:Cdk2-associated events at S phase entry
R-ATH-983168 Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

PROiPR:Q147G5

Gene expression databases

ExpressionAtlasiQ147G5 baseline and differential
GenevisibleiQ147G5 AT

Family and domain databases

CDDicd00043 CYCLIN, 2 hits
InterProiView protein in InterPro
IPR039361 Cyclin
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR004367 Cyclin_C-dom
IPR006671 Cyclin_N
PANTHERiPTHR10177 PTHR10177, 2 hits
PfamiView protein in Pfam
PF02984 Cyclin_C, 1 hit
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 2 hits
SM01332 Cyclin_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits
PROSITEiView protein in PROSITE
PS00292 CYCLINS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCCA22_ARATH
AccessioniPrimary (citable) accession number: Q147G5
Secondary accession number(s): Q39073, Q9LFM7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: August 22, 2006
Last modified: July 18, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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