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UniProtKB - Q14714 (SSPN_HUMAN)

Entry version 151 (16 Oct 2019)
Sequence version 3 (01 Oct 2000)
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Protein

Sarcospan

Gene

SSPN

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q14714

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sarcospan
Alternative name(s):
K-ras oncogene-associated protein
Kirsten-ras-associated protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SSPN
Synonyms:KRAG
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:11322 SSPN

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		601599 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q14714

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 53CytoplasmicSequence analysisAdd BLAST53
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei54 – 74HelicalSequence analysisAdd BLAST21
Topological domaini75 – 86ExtracellularSequence analysisAdd BLAST12
Transmembranei87 – 107HelicalSequence analysisAdd BLAST21
Topological domaini108 – 122CytoplasmicSequence analysisAdd BLAST15
Transmembranei123 – 143HelicalSequence analysisAdd BLAST21
Topological domaini144 – 193ExtracellularSequence analysisAdd BLAST50
Transmembranei194 – 214HelicalSequence analysisAdd BLAST21
Topological domaini215 – 243CytoplasmicSequence analysisAdd BLAST29

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		8082

Open Targets

More...OpenTargetsi		ENSG00000123096

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA36146

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q14714

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SSPN

Domain mapping of disease mutations (DMDM)

More...DMDMi		13431900

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000722261 – 243SarcospanAdd BLAST243

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q14714

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q14714

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q14714

PeptideAtlas

More...PeptideAtlasi		Q14714

PRoteomics IDEntifications database

More...PRIDEi		Q14714

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		3623
60142 [Q14714-1]
60143 [Q14714-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q14714

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q14714

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q14714

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform 1 is expressed exclusively in heart and skeletal muscle. Isoform 2 is expressed in heart, skeletal muscle, thymus, prostate, testis, ovary, small intestine, colon and spleen.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000123096 Expressed in 237 organ(s), highest expression level in myometrium

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q14714 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q14714 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA066432

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		113755, 1 interactor

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q14714

Protein interaction database and analysis system

More...IntActi		Q14714, 2 interactors

Molecular INTeraction database

More...MINTi		Q14714

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000242729

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IK33 Eukaryota
ENOG4111WM7 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000007747

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000065718

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q14714

KEGG Orthology (KO)

More...KOi		K22194

Identification of Orthologs from Complete Genome Data

More...OMAi		HRYQVFF

Database of Orthologous Groups

More...OrthoDBi		629563at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q14714

TreeFam database of animal gene trees

More...TreeFami		TF332100

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR007237 CD20-like
IPR030429 Sarcospan

The PANTHER Classification System

More...PANTHERi		PTHR15260 PTHR15260, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF04103 CD20, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q14714-1) [UniParc]FASTAAdd to basket
Also known as: SPN1

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGKNKQPRGQ QRQGGPPAAD AAGPDDMEPK KGTGAPKECG EEEPRTCCGC 
        60         70         80         90        100
RFPLLLALLQ LALGIAVTVV GFLMASISSS LLVRDTPFWA GIIVCLVAYL 
       110        120        130        140        150
GLFMLCVSYQ VDERTCIQFS MKLLYFLLSA LGLTVCVLAV AFAAHHYSQL 
       160        170        180        190        200
TQFTCETTLD SCQCKLPSSE PLSRTFVYRD VTDCTSVTGT FKLFLLIQMI 
       210        220        230        240 
LNLVCGLVCL LACFVMWKHR YQVFYVGVRI CSLTASEGPQ QKI
Length:243
Mass (Da):26,618
Last modified:October 1, 2000 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0D6B24B9848253F9
GO
Isoform 2 (identifier: Q14714-2) [UniParc]FASTAAdd to basket
Also known as: SPN2

The sequence of this isoform differs from the canonical sequence as follows:
     108-218: Missing.

Show »
Length:132
Mass (Da):14,126
Checksum:i65539CE9E96797E6
GO
Isoform 3 (identifier: Q14714-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-103: Missing.

Note: No experimental confirmation available.
Show »
Length:140
Mass (Da):15,820
Checksum:i83EBCA15741F4F47
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H0K2F5H0K2_HUMAN
Sarcospan
SSPN
128Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H381F5H381_HUMAN
Sarcospan
SSPN
120Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti13Missing (PubMed:9395445).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_051384186S → N. Corresponds to variant dbSNP:rs12313670Ensembl.1
Natural variantiVAR_051385228V → I. Corresponds to variant dbSNP:rs12313736Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0463511 – 103Missing in isoform 3. 1 PublicationAdd BLAST103
Alternative sequenceiVSP_004431108 – 218Missing in isoform 2. 2 PublicationsAdd BLAST111

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF016028 mRNA Translation: AAC61660.2
AL136756 mRNA Translation: CAB66690.1
AK092925 mRNA Translation: BAG52629.1
AC022509 Genomic DNA No translation available.
AC055720 Genomic DNA No translation available.
BC062299 mRNA Translation: AAH62299.1
X89105 mRNA Translation: CAA61479.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS44850.1 [Q14714-3]
CCDS8707.1 [Q14714-1]

Protein sequence database of the Protein Information Resource

More...PIRi		S57712

NCBI Reference Sequences

More...RefSeqi		NP_001129295.1, NM_001135823.1 [Q14714-3]
NP_005077.2, NM_005086.4 [Q14714-1]
XP_011519155.1, XM_011520853.2 [Q14714-3]
XP_011519156.1, XM_011520854.2 [Q14714-3]
XP_011519157.1, XM_011520855.2 [Q14714-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000242729; ENSP00000242729; ENSG00000123096 [Q14714-1]
ENST00000422622; ENSP00000396087; ENSG00000123096 [Q14714-3]
ENST00000540266; ENSP00000442893; ENSG00000123096 [Q14714-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		8082

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:8082

UCSC genome browser

More...UCSCi		uc001rhd.4 human [Q14714-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF016028 mRNA Translation: AAC61660.2
AL136756 mRNA Translation: CAB66690.1
AK092925 mRNA Translation: BAG52629.1
AC022509 Genomic DNA No translation available.
AC055720 Genomic DNA No translation available.
BC062299 mRNA Translation: AAH62299.1
X89105 mRNA Translation: CAA61479.1
CCDSiCCDS44850.1 [Q14714-3]
CCDS8707.1 [Q14714-1]
PIRiS57712
RefSeqiNP_001129295.1, NM_001135823.1 [Q14714-3]
NP_005077.2, NM_005086.4 [Q14714-1]
XP_011519155.1, XM_011520853.2 [Q14714-3]
XP_011519156.1, XM_011520854.2 [Q14714-3]
XP_011519157.1, XM_011520855.2 [Q14714-3]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGridi113755, 1 interactor
CORUMiQ14714
IntActiQ14714, 2 interactors
MINTiQ14714
STRINGi9606.ENSP00000242729

PTM databases

iPTMnetiQ14714
PhosphoSitePlusiQ14714
SwissPalmiQ14714

Polymorphism and mutation databases

BioMutaiSSPN
DMDMi13431900

Proteomic databases

jPOSTiQ14714
MassIVEiQ14714
PaxDbiQ14714
PeptideAtlasiQ14714
PRIDEiQ14714
ProteomicsDBi3623
60142 [Q14714-1]
60143 [Q14714-2]

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		8082

Genome annotation databases

EnsembliENST00000242729; ENSP00000242729; ENSG00000123096 [Q14714-1]
ENST00000422622; ENSP00000396087; ENSG00000123096 [Q14714-3]
ENST00000540266; ENSP00000442893; ENSG00000123096 [Q14714-3]
GeneIDi8082
KEGGihsa:8082
UCSCiuc001rhd.4 human [Q14714-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		8082
DisGeNETi8082

GeneCards: human genes, protein and diseases

More...GeneCardsi		SSPN
HGNCiHGNC:11322 SSPN
HPAiHPA066432
MIMi601599 gene
neXtProtiNX_Q14714
OpenTargetsiENSG00000123096
PharmGKBiPA36146

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IK33 Eukaryota
ENOG4111WM7 LUCA
GeneTreeiENSGT00390000007747
HOGENOMiHOG000065718
InParanoidiQ14714
KOiK22194
OMAiHRYQVFF
OrthoDBi629563at2759
PhylomeDBiQ14714
TreeFamiTF332100

Enzyme and pathway databases

SIGNORiQ14714

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SSPN human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		8082
PharosiQ14714

Protein Ontology

More...PROi		PR:Q14714

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000123096 Expressed in 237 organ(s), highest expression level in myometrium
ExpressionAtlasiQ14714 baseline and differential
GenevisibleiQ14714 HS

Family and domain databases

InterProiView protein in InterPro
IPR007237 CD20-like
IPR030429 Sarcospan
PANTHERiPTHR15260 PTHR15260, 1 hit
PfamiView protein in Pfam
PF04103 CD20, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSSPN_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q14714
Secondary accession number(s): B3KS67
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 1, 2000
Last modified: October 16, 2019
This is version 151 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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