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UniProtKB - Q14585 (ZN345_HUMAN)

Entry version 190 (10 Feb 2021)
Sequence version 1 (01 Nov 1996)
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Protein

Zinc finger protein 345

Gene

ZNF345

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri62 – 84C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri90 – 112C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri118 – 140C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri146 – 168C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri174 – 196C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri202 – 224C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri230 – 252C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri258 – 280C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri286 – 308C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri314 – 336C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri342 – 364C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri370 – 392C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri398 – 420C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri426 – 448C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri454 – 476C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q14585

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 345
Alternative name(s):
Zinc finger protein HZF10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF345
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:16367, ZNF345

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q14585

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000251247.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000251247

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38128

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q14585, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF345

Domain mapping of disease mutations (DMDM)

More...DMDMi		11136080

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000475441 – 488Zinc finger protein 345Add BLAST488

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q14585

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q14585

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q14585

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q14585

PeptideAtlas

More...PeptideAtlasi		Q14585

PRoteomics IDEntifications database

More...PRIDEi		Q14585

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		60058

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q14585

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q14585

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000251247, Expressed in right testis and 154 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q14585, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q14585, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000251247, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		117374, 3 interactors

Protein interaction database and analysis system

More...IntActi		Q14585, 8 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000431202

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q14585, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q14585

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri62 – 84C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri90 – 112C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri118 – 140C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri146 – 168C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri174 – 196C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri202 – 224C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri230 – 252C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri258 – 280C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri286 – 308C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri314 – 336C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri342 – 364C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri370 – 392C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri398 – 420C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri426 – 448C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri454 – 476C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000163308

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_0_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q14585

Identification of Orthologs from Complete Genome Data

More...OMAi		MPTFNTQ

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q14585

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 11 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 15 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 8 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 15 hits
PS50157, ZINC_FINGER_C2H2_2, 15 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

Q14585-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENLTKHSIE CSSFRGDWEC KNQFERKQGS QEGHFSEMIF TPEDMPTFSI 
        60         70         80         90        100
QHQRIHTDEK LLECKECGKD FSFVSVLVRH QRIHTGEKPY ECKECGKAFG 
       110        120        130        140        150
SGANLAYHQR IHTGEKPFEC KECGKAFGSG SNLTHHQRIH TGEKPYECKE 
       160        170        180        190        200
CGKAFSFGSG LIRHQIIHSG EKPYECKECG KSFSFESALI RHHRIHTGEK 
       210        220        230        240        250
PYECIDCGKA FGSGSNLTQH RRIHTGEKPY ECKACGMAFS SGSALTRHQR 
       260        270        280        290        300
IHTGEKPYIC NECGKAFSFG SALTRHQRIH TGEKPYVCKE CGKAFNSGSD 
       310        320        330        340        350
LTQHQRIHTG EKPYECKECE KAFRSGSKLI QHQRMHTGEK PYECKECGKT 
       360        370        380        390        400
FSSGSDLTQH HRIHTGEKPY ECKECGKAFG SGSKLIQHQL IHTGERPYEC 
       410        420        430        440        450
KECGKSFSSG SALNRHQRIH TGEKPYECKE CGKAFYSGSS LTQHQRIHTG 
       460        470        480 
EKLYECKNCG KAYGRDSEFQ QHKKSHNGKK LCELETIN
Length:488
Mass (Da):55,383
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0BDC436E4451285B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EKZ8K7EKZ8_HUMAN
Zinc finger protein 345
ZNF345
184Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PLT7E9PLT7_HUMAN
Zinc finger protein 345
ZNF345
74Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W8R5F8W8R5_HUMAN
Zinc finger protein 345
ZNF345
113Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EM63K7EM63_HUMAN
Zinc finger protein 345
ZNF345
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2PPI4A0A1W2PPI4_HUMAN
Zinc finger protein 345
ZNF345
321Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EQ01K7EQ01_HUMAN
Zinc finger protein 345
ZNF345
75Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ESK8K7ESK8_HUMAN
Zinc finger protein 345
ZNF345
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X78933 mRNA Translation: CAA55533.1
BC032863 mRNA Translation: AAH32863.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12497.1

Protein sequence database of the Protein Information Resource

More...PIRi		S47072

NCBI Reference Sequences

More...RefSeqi		NP_001229401.1, NM_001242472.1
NP_001229403.1, NM_001242474.1
NP_001229404.1, NM_001242475.1
NP_001229405.1, NM_001242476.1
NP_003410.1, NM_003419.4
XP_011525006.1, XM_011526704.2
XP_016882057.1, XM_017026568.1
XP_016882058.1, XM_017026569.1
XP_016882059.1, XM_017026570.1
XP_016882060.1, XM_017026571.1
XP_016882061.1, XM_017026572.1
XP_016882062.1, XM_017026573.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000420450; ENSP00000431216; ENSG00000251247
ENST00000529555; ENSP00000431202; ENSG00000251247
ENST00000589046; ENSP00000465431; ENSG00000251247
ENST00000612719; ENSP00000482400; ENSG00000251247
ENST00000614069; ENSP00000477522; ENSG00000251247

Database of genes from NCBI RefSeq genomes

More...GeneIDi		25850

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:25850

UCSC genome browser

More...UCSCi		uc002oex.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78933 mRNA Translation: CAA55533.1
BC032863 mRNA Translation: AAH32863.1
CCDSiCCDS12497.1
PIRiS47072
RefSeqiNP_001229401.1, NM_001242472.1
NP_001229403.1, NM_001242474.1
NP_001229404.1, NM_001242475.1
NP_001229405.1, NM_001242476.1
NP_003410.1, NM_003419.4
XP_011525006.1, XM_011526704.2
XP_016882057.1, XM_017026568.1
XP_016882058.1, XM_017026569.1
XP_016882059.1, XM_017026570.1
XP_016882060.1, XM_017026571.1
XP_016882061.1, XM_017026572.1
XP_016882062.1, XM_017026573.1

3D structure databases

SMRiQ14585
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi117374, 3 interactors
IntActiQ14585, 8 interactors
STRINGi9606.ENSP00000431202

PTM databases

iPTMnetiQ14585
PhosphoSitePlusiQ14585

Genetic variation databases

BioMutaiZNF345
DMDMi11136080

Proteomic databases

jPOSTiQ14585
MassIVEiQ14585
MaxQBiQ14585
PaxDbiQ14585
PeptideAtlasiQ14585
PRIDEiQ14585
ProteomicsDBi60058

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		47728, 87 antibodies

The DNASU plasmid repository

More...DNASUi		25850

Genome annotation databases

EnsembliENST00000420450; ENSP00000431216; ENSG00000251247
ENST00000529555; ENSP00000431202; ENSG00000251247
ENST00000589046; ENSP00000465431; ENSG00000251247
ENST00000612719; ENSP00000482400; ENSG00000251247
ENST00000614069; ENSP00000477522; ENSG00000251247
GeneIDi25850
KEGGihsa:25850
UCSCiuc002oex.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		25850

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF345
HGNCiHGNC:16367, ZNF345
HPAiENSG00000251247, Low tissue specificity
neXtProtiNX_Q14585
OpenTargetsiENSG00000251247
PharmGKBiPA38128
VEuPathDBiHostDB:ENSG00000251247.9

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000163308
HOGENOMiCLU_002678_0_2_1
InParanoidiQ14585
OMAiMPTFNTQ
OrthoDBi1318335at2759
PhylomeDBiQ14585

Enzyme and pathway databases

PathwayCommonsiQ14585

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		25850, 10 hits in 893 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF345, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		25850
PharosiQ14585, Tdark

Protein Ontology

More...PROi		PR:Q14585
RNActiQ14585, protein

Gene expression databases

BgeeiENSG00000251247, Expressed in right testis and 154 other tissues
ExpressionAtlasiQ14585, baseline and differential
GenevisibleiQ14585, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 11 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 15 hits
SUPFAMiSSF57667, SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 15 hits
PS50157, ZINC_FINGER_C2H2_2, 15 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN345_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q14585
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: February 10, 2021
This is version 190 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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