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Protein

ELAV-like protein 3

Gene

ELAVL3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance.By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • AU-rich element binding Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, RNA-binding
Biological processDifferentiation, Neurogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ELAV-like protein 3
Alternative name(s):
Hu-antigen C
Short name:
HuC
Paraneoplastic cerebellar degeneration-associated antigen
Paraneoplastic limbic encephalitis antigen 21
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ELAVL3
Synonyms:HUC, PLE21
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000196361.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:3314 ELAVL3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603458 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q14576

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
1995

Open Targets

More...
OpenTargetsi
ENSG00000196361

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA27742

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ELAVL3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
21264436

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000815811 – 367ELAV-like protein 3Add BLAST367

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q14576

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q14576

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q14576

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q14576

PeptideAtlas

More...
PeptideAtlasi
Q14576

PRoteomics IDEntifications database

More...
PRIDEi
Q14576

ProteomicsDB human proteome resource

More...
ProteomicsDBi
60054
60055 [Q14576-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q14576

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q14576

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Brain specific.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000196361 Expressed in 221 organ(s), highest expression level in cerebral cortex

CleanEx database of gene expression profiles

More...
CleanExi
HS_ELAVL3

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q14576 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q14576 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB013066

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
108310, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q14576, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000352162

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q14576

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q14576

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 117RRM 1PROSITE-ProRule annotationAdd BLAST79
Domaini125 – 205RRM 2PROSITE-ProRule annotationAdd BLAST81
Domaini284 – 362RRM 3PROSITE-ProRule annotationAdd BLAST79

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

RRM 1 and RRM 2 bind cooperatively to AU-rich sequences in target mRNAs. RRM 3 binds to poly-A mRNA sequences (By similarity).By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RRM elav family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0145 Eukaryota
ENOG410XP7S LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160389

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231162

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG002295

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q14576

KEGG Orthology (KO)

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KOi
K13208

Identification of Orthologs from Complete Genome Data

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OMAi
SSAGWCI

Database of Orthologous Groups

More...
OrthoDBi
614259at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q14576

TreeFam database of animal gene trees

More...
TreeFami
TF313377

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12650 RRM1_Hu, 1 hit
cd12655 RRM3_HuC, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006548 ELAD_HU_SF
IPR034775 ELAV/Hu_RRM1
IPR034915 HuC_RRM3
IPR002343 Hud_Sxl_RNA
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076 RRM_1, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00961 HUDSXLRNA

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360 RRM, 3 hits
SM00361 RRM_1, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01661 ELAV_HUD_SF, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q14576-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVTQILGAME SQVGGGPAGP ALPNGPLLGT NGATDDSKTN LIVNYLPQNM
60 70 80 90 100
TQDEFKSLFG SIGDIESCKL VRDKITGQSL GYGFVNYSDP NDADKAINTL
110 120 130 140 150
NGLKLQTKTI KVSYARPSSA SIRDANLYVS GLPKTMSQKE MEQLFSQYGR
160 170 180 190 200
IITSRILVDQ VTGVSRGVGF IRFDKRIEAE EAIKGLNGQK PLGAAEPITV
210 220 230 240 250
KFANNPSQKT GQALLTHLYQ SSARRYAGPL HHQTQRFRLD NLLNMAYGVK
260 270 280 290 300
SPLSLIARFS PIAIDGMSGL AGVGLSGGAA GAGWCIFVYN LSPEADESVL
310 320 330 340 350
WQLFGPFGAV TNVKVIRDFT TNKCKGFGFV TMTNYDEAAM AIASLNGYRL
360
GERVLQVSFK TSKQHKA
Length:367
Mass (Da):39,547
Last modified:May 27, 2002 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i03FB3BD4D112B326
GO
Isoform 2 (identifier: Q14576-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     251-257: Missing.

Show »
Length:360
Mass (Da):38,865
Checksum:i9D649E3D50AC1797
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EPB5K7EPB5_HUMAN
ELAV-like protein 3
ELAVL3
92Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti20 – 25PALPNG → RPAQR in BAA21838 (PubMed:15489334).Curated6
Sequence conflicti78 – 79QS → RD in AAA58677 (Ref. 1) Curated2
Sequence conflicti78 – 79QS → RD in AAK67714 (Ref. 2) Curated2
Sequence conflicti88S → P in AAA58677 (Ref. 1) Curated1
Sequence conflicti88S → P in AAK67714 (Ref. 2) Curated1
Sequence conflicti195A → R in BAA21838 (PubMed:15489334).Curated1
Sequence conflicti248G → A in BAA21838 (PubMed:15489334).Curated1
Sequence conflicti282Missing in AAA58677 (Ref. 1) Curated1
Sequence conflicti282Missing in BAA21838 (PubMed:15489334).Curated1
Sequence conflicti295 – 297ADE → PDQ in BAA21838 (PubMed:15489334).Curated3
Sequence conflicti330V → M in BAA21838 (PubMed:15489334).Curated1
Sequence conflicti351G → A in AAA58677 (Ref. 1) Curated1
Sequence conflicti352E → Q in BAA21838 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_005789251 – 257Missing in isoform 2. 3 Publications7

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L26405 mRNA Translation: AAA58677.1
AY036909 mRNA Translation: AAK67714.1
AC008481 Genomic DNA No translation available.
BC014144 mRNA No translation available.
D26158 mRNA Translation: BAA21838.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32912.1 [Q14576-1]
CCDS45978.1 [Q14576-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001411.2, NM_001420.3 [Q14576-1]
NP_115657.2, NM_032281.2 [Q14576-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.1701

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000359227; ENSP00000352162; ENSG00000196361 [Q14576-1]
ENST00000438662; ENSP00000390878; ENSG00000196361 [Q14576-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1995

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:1995

UCSC genome browser

More...
UCSCi
uc002mrx.2 human [Q14576-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L26405 mRNA Translation: AAA58677.1
AY036909 mRNA Translation: AAK67714.1
AC008481 Genomic DNA No translation available.
BC014144 mRNA No translation available.
D26158 mRNA Translation: BAA21838.1
CCDSiCCDS32912.1 [Q14576-1]
CCDS45978.1 [Q14576-2]
RefSeqiNP_001411.2, NM_001420.3 [Q14576-1]
NP_115657.2, NM_032281.2 [Q14576-2]
UniGeneiHs.1701

3D structure databases

ProteinModelPortaliQ14576
SMRiQ14576
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi108310, 11 interactors
IntActiQ14576, 7 interactors
STRINGi9606.ENSP00000352162

PTM databases

iPTMnetiQ14576
PhosphoSitePlusiQ14576

Polymorphism and mutation databases

BioMutaiELAVL3
DMDMi21264436

Proteomic databases

EPDiQ14576
jPOSTiQ14576
MaxQBiQ14576
PaxDbiQ14576
PeptideAtlasiQ14576
PRIDEiQ14576
ProteomicsDBi60054
60055 [Q14576-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000359227; ENSP00000352162; ENSG00000196361 [Q14576-1]
ENST00000438662; ENSP00000390878; ENSG00000196361 [Q14576-2]
GeneIDi1995
KEGGihsa:1995
UCSCiuc002mrx.2 human [Q14576-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1995
DisGeNETi1995
EuPathDBiHostDB:ENSG00000196361.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ELAVL3
HGNCiHGNC:3314 ELAVL3
HPAiCAB013066
MIMi603458 gene
neXtProtiNX_Q14576
OpenTargetsiENSG00000196361
PharmGKBiPA27742

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0145 Eukaryota
ENOG410XP7S LUCA
GeneTreeiENSGT00940000160389
HOGENOMiHOG000231162
HOVERGENiHBG002295
InParanoidiQ14576
KOiK13208
OMAiSSAGWCI
OrthoDBi614259at2759
PhylomeDBiQ14576
TreeFamiTF313377

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ELAVL3 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
ELAVL3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
1995

Protein Ontology

More...
PROi
PR:Q14576

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000196361 Expressed in 221 organ(s), highest expression level in cerebral cortex
CleanExiHS_ELAVL3
ExpressionAtlasiQ14576 baseline and differential
GenevisibleiQ14576 HS

Family and domain databases

CDDicd12650 RRM1_Hu, 1 hit
cd12655 RRM3_HuC, 1 hit
Gene3Di3.30.70.330, 3 hits
InterProiView protein in InterPro
IPR006548 ELAD_HU_SF
IPR034775 ELAV/Hu_RRM1
IPR034915 HuC_RRM3
IPR002343 Hud_Sxl_RNA
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk
PfamiView protein in Pfam
PF00076 RRM_1, 3 hits
PRINTSiPR00961 HUDSXLRNA
SMARTiView protein in SMART
SM00360 RRM, 3 hits
SM00361 RRM_1, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
TIGRFAMsiTIGR01661 ELAV_HUD_SF, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiELAV3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q14576
Secondary accession number(s): Q16135, Q96CL8, Q96QS9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: May 27, 2002
Last modified: January 16, 2019
This is version 161 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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