WFDC2

Protein namesⁱ	Recommended name: WAP four-disulfide core domain protein 2 Alternative name(s): Epididymal secretory protein E4 Major epididymis-specific protein E4 Putative protease inhibitor WAP5
Gene namesⁱ	Name:WFDC2 Synonyms:HE4, WAP5
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 20

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000101443.17
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:15939 WFDC2
MIMⁱ	617548 gene
neXtProtⁱ	NX_Q14508

Keywords - Cellular componentⁱ

Secreted

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	10406
Open Targets More...OpenTargetsⁱ	ENSG00000101443
PharmGKBⁱ	PA38059

Polymorphism and mutation databases

BioMutaⁱ	WFDC2
DMDMⁱ	20141958

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 30	Sequence analysisAdd BLAST		30
ChainⁱPRO_0000041370	31 – 124	WAP four-disulfide core domain protein 2Add BLAST		94

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Disulfide bondⁱ	36 ↔ 62	PROSITE-ProRule annotation
Glycosylationⁱ	44	N-linked (GlcNAc...) asparagine2 Publications	1
Disulfide bondⁱ	45 ↔ 66	PROSITE-ProRule annotation
Disulfide bondⁱ	49 ↔ 61	PROSITE-ProRule annotation
Disulfide bondⁱ	55 ↔ 70	PROSITE-ProRule annotation
Disulfide bondⁱ	80 ↔ 110	PROSITE-ProRule annotation
Disulfide bondⁱ	93 ↔ 114	PROSITE-ProRule annotation
Disulfide bondⁱ	97 ↔ 109	PROSITE-ProRule annotation
Disulfide bondⁱ	103 ↔ 119	PROSITE-ProRule annotation

Keywords - PTMⁱ

Disulfide bond, Glycoprotein

Proteomic databases

EPDⁱ	Q14508
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q14508
PaxDbⁱ	Q14508
PeptideAtlas More...PeptideAtlasⁱ	Q14508
PRIDEⁱ	Q14508
ProteomicsDBⁱ	60010 60011 [Q14508-2] 60012 [Q14508-3] 60013 [Q14508-4] 60014 [Q14508-5]

PTM databases

GlyConnectⁱ	1902
iPTMnetⁱ	Q14508

Expressionⁱ

Tissue specificityⁱ

Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis.1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000101443 Expressed in 113 organ(s), highest expression level in adult mammalian kidney
CleanExⁱ	HS_WFDC2
ExpressionAtlasⁱ	Q14508 baseline and differential
Genevisibleⁱ	Q14508 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA042302

HPAⁱ

HPA042302

Interactionⁱ

Subunit structureⁱ

Homotrimer; disulfide-linked.1 Publication

Protein-protein interaction databases

BioGridⁱ	115677, 14 interactors
IntActⁱ	Q14508, 15 interactors
STRINGⁱ	9606.ENSP00000361761

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q14508
SMRⁱ	Q14508
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	31 – 73	WAP 1PROSITE-ProRule annotationAdd BLAST		43
Domainⁱ	74 – 123	WAP 2PROSITE-ProRule annotationAdd BLAST		50

Keywords - Domainⁱ

Repeat, Signal

Phylogenomic databases

eggNOGⁱ	ENOG410J36N Eukaryota ENOG41125F3 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00730000111410
HOVERGENⁱ	HBG018073
InParanoidⁱ	Q14508
OMAⁱ	DLNCTQE
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0UW4
PhylomeDBⁱ	Q14508

Family and domain databases

Gene3Dⁱ	4.10.75.10, 2 hits
InterProⁱ	View protein in InterPro IPR036645 Elafin-like_sf IPR008197 WAP_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00095 WAP, 2 hits
PRINTSⁱ	PR00003 4DISULPHCORE
SMARTⁱ	View protein in SMART SM00217 WAP, 2 hits
SUPFAMⁱ	SSF57256 SSF57256, 2 hits
PROSITEⁱ	View protein in PROSITE PS51390 WAP, 2 hits

Sequences (5+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 5 isoformsⁱ produced by alternative splicing. Align Add to basket

Note: Additional isoforms seem to exist.

This entry has 5 described isoforms and 1 potential isoform that is computationally mapped.Show all Align All

Isoform 1 (identifier: Q14508-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPACRLGPLA AALLLSLLLF GFTLVSGTGA EKTGVCPELQ ADQNCTQECV 
        60         70         80         90        100
SDSECADNLK CCSAGCATFC SLPNDKEGSC PQVNINFPQL GLCRDQCQVD 
       110        120 
SQCPGQMKCC RNGCGKVSCV TPNF

Length:124

Mass (Da):12,993

Last modified:January 23, 2002 - v2

Checksum:ⁱ9536B00B385259AD

GO

Isoform 2 (identifier: Q14508-2) [UniParc]FASTA Add to basket

Also known as: HE4-V3

The sequence of this isoform differs from the canonical sequence as follows:
2-23: PACRLGPLAAALLLSLLLFGFT → LQVQVNLPVSPLPTYPYSFFYP
24-74: Missing.

« Hide

        10         20         30         40         50
MLQVQVNLPV SPLPTYPYSF FYPDKEGSCP QVNINFPQLG LCRDQCQVDS 
        60         70 
QCPGQMKCCR NGCGKVSCVT PNF

Show »

Length:73

Mass (Da):8,120

Checksum:ⁱBDCFEECFA4FE8D59

GO

Isoform 3 (identifier: Q14508-3) [UniParc]FASTA Add to basket

Also known as: HE4-V2

The sequence of this isoform differs from the canonical sequence as follows:
27-74: Missing.

« Hide

        10         20         30         40         50
MPACRLGPLA AALLLSLLLF GFTLVSDKEG SCPQVNINFP QLGLCRDQCQ 
        60         70 
VDSQCPGQMK CCRNGCGKVS CVTPNF

Show »

Length:76

Mass (Da):8,108

Checksum:ⁱA93BE754FDAC93C2

GO

Isoform 4 (identifier: Q14508-4) [UniParc]FASTA Add to basket

Also known as: HE4-V1

The sequence of this isoform differs from the canonical sequence as follows:
71-79: SLPNDKEGS → LLCPNGQLAE
80-124: Missing.

« Hide

        10         20         30         40         50
MPACRLGPLA AALLLSLLLF GFTLVSGTGA EKTGVCPELQ ADQNCTQECV 
        60         70         80
SDSECADNLK CCSAGCATFC LLCPNGQLAE

Show »

Length:80

Mass (Da):8,202

Checksum:ⁱ75505D4E8301C895

GO

Isoform 5 (identifier: Q14508-5) [UniParc]FASTA Add to basket

Also known as: HE4-V4

The sequence of this isoform differs from the canonical sequence as follows:
75-102: DKEGSCPQVNINFPQLGLCRDQCQVDSQ → ALFHWHLKTRRLWEISGPRPRRPTWDSS
103-124: Missing.

« Hide

        10         20         30         40         50
MPACRLGPLA AALLLSLLLF GFTLVSGTGA EKTGVCPELQ ADQNCTQECV 
        60         70         80         90        100
SDSECADNLK CCSAGCATFC SLPNALFHWH LKTRRLWEIS GPRPRRPTWD 

SS

Show »

Length:102

Mass (Da):11,043

Checksum:ⁱ36C13D09AAD2E15B

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	A8K2M3	A8K2M3_HUMAN		WAP four-disulfide core domain 2, i... WAP four-disulfide core domain 2, isoform CRA_c (WAP four-disulfide core domain protein 2) (cDNA FLJ76533, highly similar to Homo sapiens WAP four-disulfide core domain 2 (WFDC2), transcript variant 3, mRNA)	WFDC2 hCG_38370	79	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	71 – 72	SL → LLC in CAA44869 (PubMed:1686187).Curated	2
Sequence conflictⁱ	71 – 72	SL → LLC in AAL37485 (PubMed:11965550).Curated	2
Sequence conflictⁱ	101	S → T in CAA44869 (PubMed:1686187).Curated	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_007666	2 – 23	PACRL…LFGFT → LQVQVNLPVSPLPTYPYSFF YP in isoform 2. 1 PublicationAdd BLAST	22
Alternative sequenceⁱVSP_007667	24 – 74	Missing in isoform 2. 1 PublicationAdd BLAST	51
Alternative sequenceⁱVSP_007668	27 – 74	Missing in isoform 3. 1 PublicationAdd BLAST	48
Alternative sequenceⁱVSP_007669	71 – 79	SLPNDKEGS → LLCPNGQLAE in isoform 4. 1 Publication	9
Alternative sequenceⁱVSP_007670	75 – 102	DKEGS…QVDSQ → ALFHWHLKTRRLWEISGPRP RRPTWDSS in isoform 5. 1 PublicationAdd BLAST	28
Alternative sequenceⁱVSP_007671	80 – 124	Missing in isoform 4. 1 PublicationAdd BLAST	45
Alternative sequenceⁱVSP_007672	103 – 124	Missing in isoform 5. 1 PublicationAdd BLAST	22

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X63187 mRNA Translation: CAA44869.1 AF330259 mRNA Translation: AAL37485.1 AF330260 mRNA Translation: AAL37486.1 AF330261 mRNA Translation: AAL37487.1 AF330262 mRNA Translation: AAL37488.1 AY212888 mRNA Translation: AAO52683.1 CR456977 mRNA Translation: CAG33258.1 AL031663 Genomic DNA No translation available. CH471077 Genomic DNA Translation: EAW75836.1 CH471077 Genomic DNA Translation: EAW75837.1 CH471077 Genomic DNA Translation: EAW75839.1 BC046106 mRNA Translation: AAH46106.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS35501.1 [Q14508-1]
PIRⁱ	S25454
NCBI Reference Sequences More...RefSeqⁱ	NP_006094.3, NM_006103.3 [Q14508-1]
UniGeneⁱ	Hs.2719

Genome annotation databases

Ensemblⁱ	ENST00000217425; ENSP00000217425; ENSG00000101443 [Q14508-5] ENST00000339946; ENSP00000340215; ENSG00000101443 [Q14508-3] ENST00000342873; ENSP00000342890; ENSG00000101443 [Q14508-2] ENST00000372676; ENSP00000361761; ENSG00000101443 [Q14508-1]
GeneIDⁱ	10406
KEGGⁱ	hsa:10406
UCSC genome browser More...UCSCⁱ	uc002xoo.4 human [Q14508-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q14508	WAP four-disulfide core domain 2		PANTR		124	UniRef100_Q14508
Uncharacterized protein		PANPA		124
WAP four-disulfide core domain 2		GORGO		124
Q14508-3	WAP four-disulfide core domain 2		PANTR		76	UniRef100_A0A2I3TX61
Uncharacterized protein		PANPA		76
WAP four-disulfide core domain 2		GORGO		76
Q14508-5	WAP four-disulfide core domain 2		PANTR		102	UniRef100_A0A2I3T2T6
Uncharacterized protein		PANPA		102
WAP four-disulfide core domain 2		GORGO		102

Protein	Similar proteins		Species	Score	Length	Source
Q14508	WAP four-disulfide core domain 2		PANTR		124	UniRef90_Q14508
Uncharacterized protein		PANPA		124
WAP four-disulfide core domain 2		GORGO		124
WAP four-disulfide core domain 2		AOTNA		124
WAP four-disulfide core domain 2		SAIBB		124
+16
Q14508-2	WFDC2 isoform 3		PONAB		73	UniRef90_Q14508-2
WFDC2 isoform 2 (Fragment)		PANTR		73
Q14508-3	WAP four-disulfide core domain 2		PANTR		76	UniRef90_A0A2I3TX61
Uncharacterized protein		PANPA		76
WAP four-disulfide core domain 2		GORGO		76
WAP four-disulfide core domain 2		SAIBB		76
Uncharacterized protein		Cebus capucinus imitator		76
+12
Q14508-4	WAP four-disulfide core domain 2, isoform CRA_c		HUMAN		79	UniRef90_Q14508-4
WFDC2 isoform 6		PANTR		79
WFDC2 isoform 6		PONAB		79
UPI0008F50C47		GORGO		86
Q14508-5	WAP four-disulfide core domain 2		PANTR		102	UniRef90_A0A2I3T2T6
Uncharacterized protein		PANPA		102
WAP four-disulfide core domain 2		GORGO		102
Uncharacterized protein		NOMLE		98

Protein	Similar proteins		Species	Score	Length	Source
Q14508	WAP four-disulfide core domain protein 2		PIG		123	UniRef50_Q14508
WAP four-disulfide core domain protein 2		CANLF		124
WAP four-disulfide core domain 2		PANTR		124
Uncharacterized protein		PANPA		124
WAP four-disulfide core domain 2		GORGO		124
+44
Q14508-2	WFDC2 isoform 3		PONAB		73	UniRef50_Q14508-2
WFDC2 isoform 2 (Fragment)		PANTR		73
WAP four-disulfide core domain protein 2		MOUSE		74
Uncharacterized protein		AOTNA		76
WAP four-disulfide core domain 2		SAIBB		76
+20
Q14508-3	Isoform 2 of WAP four-disulfide core domain protein 2		HUMAN		73	UniRef50_Q14508-2
WFDC2 isoform 3		PONAB		73
WFDC2 isoform 2 (Fragment)		PANTR		73
WAP four-disulfide core domain protein 2		MOUSE		74
Uncharacterized protein		AOTNA		76
+20
Q14508-4	WAP four-disulfide core domain 2, isoform CRA_c		HUMAN		79	UniRef50_Q14508-4
WFDC2 isoform 6		PANTR		79
WFDC2 isoform 6		PONAB		79
Uncharacterized protein		AOTNA		97
WAP four-disulfide core domain 2		SAIBB		97
+8
Q14508-5	Isoform 4 of WAP four-disulfide core domain protein 2		HUMAN		80	UniRef50_Q14508-4
WFDC2 isoform 6		PANTR		79
WFDC2 isoform 6		PONAB		79
Uncharacterized protein		AOTNA		97
WAP four-disulfide core domain 2		SAIBB		97
+8

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X63187 mRNA Translation: CAA44869.1 AF330259 mRNA Translation: AAL37485.1 AF330260 mRNA Translation: AAL37486.1 AF330261 mRNA Translation: AAL37487.1 AF330262 mRNA Translation: AAL37488.1 AY212888 mRNA Translation: AAO52683.1 CR456977 mRNA Translation: CAG33258.1 AL031663 Genomic DNA No translation available. CH471077 Genomic DNA Translation: EAW75836.1 CH471077 Genomic DNA Translation: EAW75837.1 CH471077 Genomic DNA Translation: EAW75839.1 BC046106 mRNA Translation: AAH46106.1
CCDSⁱ	CCDS35501.1 [Q14508-1]
PIRⁱ	S25454
RefSeqⁱ	NP_006094.3, NM_006103.3 [Q14508-1]
UniGeneⁱ	Hs.2719

3D structure databases

ProteinModelPortalⁱ	Q14508
SMRⁱ	Q14508
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	115677, 14 interactors
IntActⁱ	Q14508, 15 interactors
STRINGⁱ	9606.ENSP00000361761

Protein family/group databases

MEROPSⁱ	I17.004

MEROPSⁱ

I17.004

PTM databases

GlyConnectⁱ	1902
iPTMnetⁱ	Q14508

Polymorphism and mutation databases

BioMutaⁱ	WFDC2
DMDMⁱ	20141958

Proteomic databases

EPDⁱ	Q14508
MaxQBⁱ	Q14508
PaxDbⁱ	Q14508
PeptideAtlasⁱ	Q14508
PRIDEⁱ	Q14508
ProteomicsDBⁱ	60010 60011 [Q14508-2] 60012 [Q14508-3] 60013 [Q14508-4] 60014 [Q14508-5]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	10406
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000217425; ENSP00000217425; ENSG00000101443 [Q14508-5] ENST00000339946; ENSP00000340215; ENSG00000101443 [Q14508-3] ENST00000342873; ENSP00000342890; ENSG00000101443 [Q14508-2] ENST00000372676; ENSP00000361761; ENSG00000101443 [Q14508-1]
GeneIDⁱ	10406
KEGGⁱ	hsa:10406
UCSCⁱ	uc002xoo.4 human [Q14508-1]

Organism-specific databases

CTDⁱ	10406
DisGeNETⁱ	10406
EuPathDBⁱ	HostDB:ENSG00000101443.17
GeneCardsⁱ	WFDC2
HGNCⁱ	HGNC:15939 WFDC2
HPAⁱ	HPA042302
MIMⁱ	617548 gene
neXtProtⁱ	NX_Q14508
OpenTargetsⁱ	ENSG00000101443
PharmGKBⁱ	PA38059
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410J36N Eukaryota ENOG41125F3 LUCA
GeneTreeⁱ	ENSGT00730000111410
HOVERGENⁱ	HBG018073
InParanoidⁱ	Q14508
OMAⁱ	DLNCTQE
OrthoDBⁱ	EOG091G0UW4
PhylomeDBⁱ	Q14508

Miscellaneous databases

ChiTaRSⁱ	WFDC2 human
GeneWikiⁱ	WFDC2
GenomeRNAiⁱ	10406
Protein Ontology More...PROⁱ	PR:Q14508
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000101443 Expressed in 113 organ(s), highest expression level in adult mammalian kidney
CleanExⁱ	HS_WFDC2
ExpressionAtlasⁱ	Q14508 baseline and differential
Genevisibleⁱ	Q14508 HS

Family and domain databases

Gene3Dⁱ	4.10.75.10, 2 hits
InterProⁱ	View protein in InterPro IPR036645 Elafin-like_sf IPR008197 WAP_dom
Pfamⁱ	View protein in Pfam PF00095 WAP, 2 hits
PRINTSⁱ	PR00003 4DISULPHCORE
SMARTⁱ	View protein in SMART SM00217 WAP, 2 hits
SUPFAMⁱ	SSF57256 SSF57256, 2 hits
PROSITEⁱ	View protein in PROSITE PS51390 WAP, 2 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	WFDC2_HUMAN
Accessionⁱ	Q14508Primary (citable) accession number: Q14508 Secondary accession number(s): A2A2A5 Q96KJ1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
	Last sequence update:	January 23, 2002
	Last modified:	October 10, 2018
	This is version 167 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 20
Human chromosome 20: entries, gene names and cross-references to MIM

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UniProtKB - Q14508 (WFDC2_HUMAN)

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WAP four-disulfide core domain protein 2

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Extracellular region or secreted

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ