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1 to 25 of 28  Show
  1. 1
    "The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins."
    Ollendorff V., Noguchi T., Delapeyriere O., Birnbaum D.
    Cell Growth Differ. 5:213-219(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Placenta.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50450 other entries.

  3. 3
    "Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression."
    Wang R., Wan Q., Kozhaya L., Fujii H., Unutmaz D.
    PLoS ONE 3:E2705-E2705(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
    Category: Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 36 other entries.

  4. 4
    "Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg."
    Stockis J., Colau D., Coulie P.G., Lucas S.
    Eur. J. Immunol. 39:3315-3322(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Category: Function, Subcellular Location, Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  5. 5
    "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
    Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.
    J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-308.
    Category: PTM / Processing.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 483 other entries.

  6. 6
    "GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells."
    Tran D.Q., Andersson J., Wang R., Ramsey H., Unutmaz D., Shevach E.M.
    Proc. Natl. Acad. Sci. U.S.A. 106:13445-13450(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH TGFB1 AND TGFB2.
    Category: Function, Subcellular Location, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 20 other entries.

  7. 7
    "Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32)."
    Chan D.V., Somani A.K., Young A.B., Massari J.V., Ohtola J., Sugiyama H., Garaczi E., Babineau D., Cooper K.D., McCormick T.S.
    BMC Biochem. 12:27-27(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: SIGNAL SEQUENCE CLEAVAGE SITE, TISSUE SPECIFICITY.
    Category: Function, PTM / Processing, Expression, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "GARP regulates the bioavailability and activation of TGFbeta."
    Wang R., Zhu J., Dong X., Shi M., Lu C., Springer T.A.
    Mol. Biol. Cell 23:1129-1139(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISULFIDE BOND, MUTAGENESIS OF CYS-211; CYS-350 AND CYS-436.
    Category: Function, Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5 and mapped to 24 other entries.

  9. 9
    "Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor beta1 (TGF-beta1) Production in Human Regulatory T Cells."
    Huygens C., Lienart S., Dedobbeleer O., Stockis J., Gauthy E., Coulie P.G., Lucas S.
    J. Biol. Chem. 290:20105-20116(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH LAPTM4B.
    Category: PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 15 other entries.

  10. 10
    Category: Function.
    Annotation: GARP is a key receptor controlling FOXP3 in T(reg) cells following T-cell activation in a positive feedback loop assisted by LGALS3 and LGMN.
    Source: GeneRIF:2615.

    This publication is mapped to 14 other entries.

  11. 11
    "Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells."
    Wang R., Kozhaya L., Mercer F., Khaitan A., Fujii H., Unutmaz D.
    Proc. Natl. Acad. Sci. U.S.A. 106:13439-13444(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Annotation: Expression of GARP on activated regulatory T cells correlates with their suppressive capacity.
    Source: GeneRIF:2615.

    This publication is mapped to 6 other entries.

  12. 12
    "New genetic associations detected in a host response study to hepatitis B vaccine."
    Davila S., Froeling F.E., Tan A., Bonnard C., Boland G.J., Snippe H., Hibberd M.L., Seielstad M.
    Genes Immun. 11:232-238(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:2615.

    This publication is mapped to 17804 other entries.

  13. 13
    Category: Sequences.
    Annotation: on chromosome 11q13.5 near the leucine-rich repeat containing 32 gene (LRRC32 also known as GARP) associated with asthma risk.
    Source: GeneRIF:2615.

    This publication is mapped to 4 other entries.

  14. 14
    Category: Function, Sequences.
    Annotation: There are 2 independent signals one in C11orf30 and the other in LRRC32 that are strongly associated with serum IgE levels. C11orf30-LRRC32 region may represent a common locus for atopic diseases via pathways involved in regulation of serum IgE levels.
    Source: GeneRIF:2615.

    This publication is mapped to 8 other entries.

  15. 15
    "miR-142-3p is involved in CD25+ CD4 T cell proliferation by targeting the expression of glycoprotein A repetitions predominant."
    Zhou Q., Haupt S., Prots I., Thummler K., Kremmer E., Lipsky P.E., Schulze-Koops H., Skapenko A.
    J. Immunol. 190:6579-6588(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: we investigated in detail miR-142-3 pregulation of GARP expression in regulatory CD25(+) CD4 T cells.
    Source: GeneRIF:2615.

    This publication is mapped to 1 other entry.

  16. 16
    "GARP is regulated by miRNAs and controls latent TGF-beta1 production by human regulatory T cells."
    Gauthy E., Cuende J., Stockis J., Huygens C., Lethe B., Collet J.F., Bommer G., Coulie P.G., Lucas S.
    PLoS ONE 8:e76186-e76186(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Function, PTM / Processing.
    Annotation: GARP is regulated by miRNAs and controls latent TGF-beta1 production by human regulatory T cells.
    Source: GeneRIF:2615.

    This publication is mapped to 1 other entry.

  17. 17
    Category: Subcellular Location.
    Annotation: GARP deficiency leads to accumulation of sphingolipid synthesis intermediates changes in sterol distribution and lysosomal dysfunction.
    Source: GeneRIF:2615.

    This publication is mapped to 14 other entries.

  18. 18
    "Methylation of an intragenic alternative promoter regulates transcription of GARP."
    Haupt S., Sontgerath V.S., Leipe J., Schulze-Koops H., Skapenko A.
    Biochim. Biophys. Acta 1859:223-234(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: since GARP functions as a transporter of transforming growth factor beta (TGFbeta) a cytokine with broad pleiotropic traits GARP transcriptional attenuation by alternative promoters might provide a mechanism regulating peripheral TGFb.
    Source: GeneRIF:2615.

    This publication is mapped to 26 other entries.

  19. 19
    "Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients."
    Abd Al Samid M., Chaudhary B., Khaled Y.S., Ammori B.J., Elkord E.
    Oncotarget 7:14083-14094(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: High GARP expression is associated with pancreatic cancer and liver metastases from colorectal cancer.
    Source: GeneRIF:2615.

    This publication is mapped to 6 other entries.

  20. 20
    "GARP: a surface molecule of regulatory T cells that is involved in the regulatory function and TGF-beta releasing."
    Sun L., Jin H., Li H.
    Oncotarget 7:42826-42836(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: GARP is a surface molecule of regulatory T cells with roles in the regulatory function and TGF-beta releasing (review).
    Source: GeneRIF:2615.

    This publication is mapped to 1 other entry.

  21. 21
    Category: Function.
    Annotation: Data show that the Treg activation marker GARP (glycoprotein A repetitions predominant) is expressed on primary melanoma.
    Source: GeneRIF:2615.

    This publication is mapped to 1 other entry.

  22. 22
    "Atopic Dermatitis According to GARP: New Mechanistic Insights in Disease Pathogenesis."
    Nousbeck J., Irvine A.D.
    J. Invest. Dermatol. 136:2340-2341(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: GARP plays an important role in the pathogenesis of atopic dermatitis.
    Source: GeneRIF:2615.

    This publication is mapped to 1 other entry.

  23. 23
    "Surface Expression of TGFbeta Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer."
    Metelli A., Wu B.X., Fugle C.W., Rachidi S., Sun S., Zhang Y., Wu J., Tomlinson S., Howe P.H., Yang Y., Garrett-Mayer E., Liu B., Li Z.
    Cancer Res. 76:7106-7117(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: these results define the oncogenic effects of the GARP-TGFbeta axis in the tumor microenvironment.
    Source: GeneRIF:2615.

    This publication is mapped to 17 other entries.

  24. 24
    "Human gingiva transcriptome during wound healing."
    Wang Y., Tatakis D.N.
    J. Clin. Periodontol. 44:394-402(2017) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: LRRC32 expression is significantly upregulated in human masticatory mucosa during wound healing.
    Source: GeneRIF:2615.

    This publication is mapped to 319 other entries.

  25. 25
    "CD4+ CD25+ GARP+ regulatory T cells display a compromised suppressive function in patients with dilated cardiomyopathy."
    Wei Y., Yu K., Wei H., Su X., Zhu R., Shi H., Sun H., Luo Q., Xu W., Xiao J., Zhong Y., Zeng Q.
    Immunology 151:291-303(2017) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: CD4(+) CD25(+) GARP(+) Treg cells are defective in dilated cardiomyopathy patients and GARP seems to be a better molecular definition of the regulatory phenotype.
    Source: GeneRIF:2615.

    This publication is mapped to 7 other entries.

1 to 25 of 28  Show
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