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Entry version 170 (07 Apr 2021)
Sequence version 1 (01 Nov 1996)
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Protein

Fibroleukin

Gene

FGL2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in physiologic lymphocyte functions at mucosal sites.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q14314

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6798695, Neutrophil degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fibroleukin
Alternative name(s):
Fibrinogen-like protein 2
pT49
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FGL2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:3696, FGL2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605351, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q14314

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000127951.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10875

Open Targets

More...
OpenTargetsi
ENSG00000127951

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA28134

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q14314, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FGL2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
12230074

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000910624 – 439FibroleukinAdd BLAST416

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi25N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi179N-linked (GlcNAc...) asparagine2 Publications1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi213 ↔ 242PROSITE-ProRule annotation
Glycosylationi235N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi263N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi336N-linked (GlcNAc...) asparagine2 Publications1
Disulfide bondi371 ↔ 384PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
CPTAC-2213
CPTAC-2214

Encyclopedia of Proteome Dynamics

More...
EPDi
Q14314

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q14314

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q14314

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q14314

PeptideAtlas

More...
PeptideAtlasi
Q14314

PRoteomics IDEntifications database

More...
PRIDEi
Q14314

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
59959

2D gel databases

REPRODUCTION-2DPAGE

More...
REPRODUCTION-2DPAGEi
Q14314

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1241, 18 N-Linked glycans (4 sites)

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q14314, 8 sites, 3 O-linked glycans (2 sites)

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q14314

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q14314

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Constitutively expressed in cytotoxic T-cells.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000127951, Expressed in blood and 234 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q14314, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q14314, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000127951, Tissue enhanced (blood)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homotetramer; disulfide-linked.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
116083, 12 interactors

Protein interaction database and analysis system

More...
IntActi
Q14314, 12 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000248598

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q14314, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini204 – 436Fibrinogen C-terminalPROSITE-ProRule annotationAdd BLAST233

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili73 – 165Sequence analysisAdd BLAST93

Keywords - Domaini

Coiled coil, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2579, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157946

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_038628_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q14314

Identification of Orthologs from Complete Genome Data

More...
OMAi
DHFYVAN

Database of Orthologous Groups

More...
OrthoDBi
357340at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q14314

TreeFam database of animal gene trees

More...
TreeFami
TF336658

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00087, FReD, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033083, Fgl2
IPR036056, Fibrinogen-like_C
IPR002181, Fibrinogen_a/b/g_C_dom
IPR020837, Fibrinogen_CS

The PANTHER Classification System

More...
PANTHERi
PTHR19143:SF189, PTHR19143:SF189, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00147, Fibrinogen_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00186, FBG, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56496, SSF56496, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00514, FIBRINOGEN_C_1, 1 hit
PS51406, FIBRINOGEN_C_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q14314-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLANWYWLS SAVLATYGFL VVANNETEEI KDERAKDVCP VRLESRGKCE
60 70 80 90 100
EAGECPYQVS LPPLTIQLPK QFSRIEEVFK EVQNLKEIVN SLKKSCQDCK
110 120 130 140 150
LQADDNGDPG RNGLLLPSTG APGEVGDNRV RELESEVNKL SSELKNAKEE
160 170 180 190 200
INVLHGRLEK LNLVNMNNIE NYVDSKVANL TFVVNSLDGK CSKCPSQEQI
210 220 230 240 250
QSRPVQHLIY KDCSDYYAIG KRSSETYRVT PDPKNSSFEV YCDMETMGGG
260 270 280 290 300
WTVLQARLDG STNFTRTWQD YKAGFGNLRR EFWLGNDKIH LLTKSKEMIL
310 320 330 340 350
RIDLEDFNGV ELYALYDQFY VANEFLKYRL HVGNYNGTAG DALRFNKHYN
360 370 380 390 400
HDLKFFTTPD KDNDRYPSGN CGLYYSSGWW FDACLSANLN GKYYHQKYRG
410 420 430
VRNGIFWGTW PGVSEAHPGG YKSSFKEAKM MIRPKHFKP
Length:439
Mass (Da):50,229
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDF34656288E49E68
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01306653G → E1 PublicationCorresponds to variant dbSNP:rs2075761Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z36531 mRNA Translation: CAA85298.1
AF104015, AF104014 Genomic DNA Translation: AAD10825.1
AF468959 Genomic DNA Translation: AAL68855.1
BC033820 mRNA Translation: AAH33820.1
BC073986 mRNA Translation: AAH73986.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5591.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I37391

NCBI Reference Sequences

More...
RefSeqi
NP_006673.1, NM_006682.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000248598; ENSP00000248598; ENSG00000127951

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10875

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10875

UCSC genome browser

More...
UCSCi
uc003ugb.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

SeattleSNPs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z36531 mRNA Translation: CAA85298.1
AF104015, AF104014 Genomic DNA Translation: AAD10825.1
AF468959 Genomic DNA Translation: AAL68855.1
BC033820 mRNA Translation: AAH33820.1
BC073986 mRNA Translation: AAH73986.1
CCDSiCCDS5591.1
PIRiI37391
RefSeqiNP_006673.1, NM_006682.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi116083, 12 interactors
IntActiQ14314, 12 interactors
STRINGi9606.ENSP00000248598

PTM databases

GlyConnecti1241, 18 N-Linked glycans (4 sites)
GlyGeniQ14314, 8 sites, 3 O-linked glycans (2 sites)
iPTMnetiQ14314
PhosphoSitePlusiQ14314

Genetic variation databases

BioMutaiFGL2
DMDMi12230074

2D gel databases

REPRODUCTION-2DPAGEiQ14314

Proteomic databases

CPTACiCPTAC-2213
CPTAC-2214
EPDiQ14314
jPOSTiQ14314
MassIVEiQ14314
PaxDbiQ14314
PeptideAtlasiQ14314
PRIDEiQ14314
ProteomicsDBi59959

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
15028, 379 antibodies

The DNASU plasmid repository

More...
DNASUi
10875

Genome annotation databases

EnsembliENST00000248598; ENSP00000248598; ENSG00000127951
GeneIDi10875
KEGGihsa:10875
UCSCiuc003ugb.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10875
DisGeNETi10875

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FGL2
HGNCiHGNC:3696, FGL2
HPAiENSG00000127951, Tissue enhanced (blood)
MIMi605351, gene
neXtProtiNX_Q14314
OpenTargetsiENSG00000127951
PharmGKBiPA28134
VEuPathDBiHostDB:ENSG00000127951.5

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2579, Eukaryota
GeneTreeiENSGT00940000157946
HOGENOMiCLU_038628_3_0_1
InParanoidiQ14314
OMAiDHFYVAN
OrthoDBi357340at2759
PhylomeDBiQ14314
TreeFamiTF336658

Enzyme and pathway databases

PathwayCommonsiQ14314
ReactomeiR-HSA-6798695, Neutrophil degranulation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
10875, 1 hit in 981 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FGL2, human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
FGL2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10875
PharosiQ14314, Tbio

Protein Ontology

More...
PROi
PR:Q14314
RNActiQ14314, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000127951, Expressed in blood and 234 other tissues
ExpressionAtlasiQ14314, baseline and differential
GenevisibleiQ14314, HS

Family and domain databases

CDDicd00087, FReD, 1 hit
InterProiView protein in InterPro
IPR033083, Fgl2
IPR036056, Fibrinogen-like_C
IPR002181, Fibrinogen_a/b/g_C_dom
IPR020837, Fibrinogen_CS
PANTHERiPTHR19143:SF189, PTHR19143:SF189, 2 hits
PfamiView protein in Pfam
PF00147, Fibrinogen_C, 1 hit
SMARTiView protein in SMART
SM00186, FBG, 1 hit
SUPFAMiSSF56496, SSF56496, 1 hit
PROSITEiView protein in PROSITE
PS00514, FIBRINOGEN_C_1, 1 hit
PS51406, FIBRINOGEN_C_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFGL2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q14314
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: November 1, 1996
Last modified: April 7, 2021
This is version 170 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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