ELOA

Functionⁱ

SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).1 Publication

Caution

It is uncertain whether Met-1 or Met-27 is the initiator.Curated

GO - Biological processⁱ

regulation of transcription by RNA polymerase II
Source: ProtInc
Traceable author statementⁱ
- 7660129
transcription by RNA polymerase II Source: Reactome
transcription elongation from RNA polymerase II promoter Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Transcription, Transcription regulation

Biological process

Transcription, Transcription regulation

Enzyme and pathway databases

Reactomeⁱ	R-HSA-112382 Formation of RNA Pol II elongation complex R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation R-HSA-167243 Tat-mediated HIV elongation arrest and recovery R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript R-HSA-167287 HIV elongation arrest and recovery R-HSA-167290 Pausing and recovery of HIV elongation R-HSA-674695 RNA Polymerase II Pre-transcription Events R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes R-HSA-75955 RNA Polymerase II Transcription Elongation

Reactomeⁱ

R-HSA-112382 Formation of RNA Pol II elongation complex
R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat
R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat
R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation
R-HSA-167243 Tat-mediated HIV elongation arrest and recovery
R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript
R-HSA-167287 HIV elongation arrest and recovery
R-HSA-167290 Pausing and recovery of HIV elongation
R-HSA-674695 RNA Polymerase II Pre-transcription Events
R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-HSA-75955 RNA Polymerase II Transcription Elongation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Elongin-A Short name: EloA Alternative name(s): Elongin 110 kDa subunit RNA polymerase II transcription factor SIII subunit A1 SIII p110 Transcription elongation factor B polypeptide 3
Gene namesⁱ	Name:ELOAImported Synonyms:TCEB3 ORF Names:MSTP059
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000011007.12
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:11620 ELOA
MIMⁱ	600786 gene
neXtProtⁱ	NX_Q14241

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6924
Open Targets More...OpenTargetsⁱ	ENSG00000011007
PharmGKBⁱ	PA36379

Polymorphism and mutation databases

BioMutaⁱ	TCEB3
DMDMⁱ	294862430

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000086960	1 – 798	Elongin-AAdd BLAST		798

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	222	PhosphoserineBy similarity	1
Modified residueⁱ	410	PhosphoserineCombined sources	1
Modified residueⁱ	413	PhosphoserineCombined sources	1
Modified residueⁱ	420	PhosphothreonineCombined sources	1
Modified residueⁱ	460	N6-acetyllysineBy similarity	1
Modified residueⁱ	542	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Acetylation, Phosphoprotein

Proteomic databases

EPDⁱ	Q14241
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q14241
PaxDbⁱ	Q14241
PeptideAtlas More...PeptideAtlasⁱ	Q14241
PRIDEⁱ	Q14241
ProteomicsDBⁱ	59938

PTM databases

iPTMnetⁱ	Q14241
PhosphoSitePlusⁱ	Q14241

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000011007 Expressed in 240 organ(s), highest expression level in upper lobe of lung
ExpressionAtlasⁱ	Q14241 baseline and differential
Genevisibleⁱ	Q14241 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA005910

HPAⁱ

HPA005910

Interactionⁱ

Subunit structureⁱ

Heterotrimer of an A (ELOA, ELOA2 or ELOA3), ELOB and ELOC subunit.By similarity

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
CEP57L1	Q8IYX8-2	3	EBI-742350,EBI-10181988
CEP70	Q8NHQ1	3	EBI-742350,EBI-739624
FAM9B	Q8IZU0	3	EBI-742350,EBI-10175124
FLJ13057	Q53SE7	3	EBI-742350,EBI-10172181
HOMEZ	Q8IX15-3	3	EBI-742350,EBI-10172004
JAKMIP2	Q96AA8	3	EBI-742350,EBI-752007
KRT40	Q6A162	3	EBI-742350,EBI-10171697
MDFI	Q99750	5	EBI-742350,EBI-724076
MID2	Q9UJV3-2	3	EBI-742350,EBI-10172526
PLK4	O00444	5	EBI-742350,EBI-746202
SPERT	Q8NA61	3	EBI-742350,EBI-741724
TRIM54	Q9BYV2	3	EBI-742350,EBI-2130429

Protein-protein interaction databases

BioGridⁱ	112786, 59 interactors
IntActⁱ	Q14241, 56 interactors
Molecular INTeraction database More...MINTⁱ	Q14241
STRINGⁱ	9606.ENSP00000395574

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	607 – 609	Combined sources	3
Helixⁱ	612 – 619	Combined sources	8
Helixⁱ	623 – 625	Combined sources	3
Helixⁱ	630 – 636	Combined sources	7
Beta strandⁱ	648 – 650	Combined sources	3
Helixⁱ	652 – 671	Combined sources	20

Show more details

3D structure databases

ProteinModelPortalⁱ	Q14241
SMRⁱ	Q14241
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	30 – 105	TFIIS N-terminalPROSITE-ProRule annotationAdd BLAST		76
Domainⁱ	592 – 636	F-boxPROSITE-ProRule annotationAdd BLAST		45

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	548 – 707	Activation domainBy similarityAdd BLAST		160
Regionⁱ	576 – 585	BC-boxBy similarity		10

Domainⁱ

The BC-box, which mediates binding to the elongin BC complex, has the consensus sequence [APST]-L-x₃-C-x₃-[AILV].By similarity

Phylogenomic databases

eggNOGⁱ	KOG2821 Eukaryota ENOG4110PG3 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000002428
HOGENOMⁱ	HOG000059565
HOVERGENⁱ	HBG051467
InParanoidⁱ	Q14241
KEGG Orthology (KO) More...KOⁱ	K15076
OMAⁱ	HLQETGI
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0D2G
PhylomeDBⁱ	Q14241
TreeFamⁱ	TF317259

Family and domain databases

Gene3Dⁱ	1.20.930.10, 1 hit
InterProⁱ	View protein in InterPro IPR001810 F-box_dom IPR010684 RNA_pol_II_trans_fac_SIII_A IPR003617 TFIIS/CRSP70_N_sub IPR035441 TFIIS/LEDGF_dom_sf IPR017923 TFIIS_N
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF06881 Elongin_A, 1 hit PF08711 Med26, 1 hit
SMARTⁱ	View protein in SMART SM00509 TFS2N, 1 hit
SUPFAMⁱ	SSF47676 SSF47676, 1 hit
PROSITEⁱ	View protein in PROSITE PS50181 FBOX, 1 hit PS51319 TFIIS_N, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

Q14241-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MHGGRSCGPR TRREPSSGEE AAPVTAMAAE SALQVVEKLQ ARLAANPDPK 
        60         70         80         90        100
KLLKYLKKLS TLPITVDILA ETGVGKTVNS LRKHEHVGSF ARDLVAQWKK 
       110        120        130        140        150
LVPVERNAEP DEQDFEKSNS RKRPRDALQK EEEMEGDYQE TWKATGSRSY 
       160        170        180        190        200
SPDHRQKKHR KLSELERPHK VSHGHERRDE RKRCHRMSPT YSSDPESSDY 
       210        220        230        240        250
GHVQSPPSCT SPHQMYVDHY RSLEEDQEPI VSHQKPGKGH SNAFQDRLGA 
       260        270        280        290        300
SQERHLGEPH GKGVVSQNKE HKSSHKDKRP VDAKSDEKAS VVSREKSHKA 
       310        320        330        340        350
LSKEENRRPP SGDNAREKPP SSGVKKEKDR EGSSLKKKCL PPSEAASDNH 
       360        370        380        390        400
LKKPKHRDPE KAKLDKSKQG LDSFDTGKGA GDLLPKVKEK GSNNLKTPEG 
       410        420        430        440        450
KVKTNLDRKS LGSLPKVEET DMEDEFEQPT MSFESYLSYD QPRKKKKKIV 
       460        470        480        490        500
KTSATALGDK GLKKNDSKST GKNLDSVQKL PKVNKTKSEK PAGADLAKLR 
       510        520        530        540        550
KVPDVLPVLP DLPLPAIQAN YRPLPSLELI SSFQPKRKAF SSPQEEEEAG 
       560        570        580        590        600
FTGRRMNSKM QVYSGSKCAY LPKMMTLHQQ CIRVLKNNID SIFEVGGVPY 
       610        620        630        640        650
SVLEPVLERC TPDQLYRIEE YNHVLIEETD QLWKVHCHRD FKEERPEEYE 
       660        670        680        690        700
SWREMYLRLQ DAREQRLRVL TKNIQFAHAN KPKGRQAKMA FVNSVAKPPR 
       710        720        730        740        750
DVRRRQEKFG TGGAAVPEKI KIKPAPYPMG SSHASASSIS FNPSPEEPAY 
       760        770        780        790 
DGPSTSSAHL APVVSSTVSY DPRKPTVKKI APMMAKTIKA FKNRFSRR

Length:798

Mass (Da):89,909

Last modified:April 20, 2010 - v2

Checksum:ⁱ2C8FD8710E27EE46

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	A0A024RAC6	A0A024RAC6_HUMAN		Elongin-A Elongin-A (Transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A), isoform CRA_a)	ELOA TCEB3, hCG_37551	772	Annotation score:

Sequence cautionⁱ

The sequence AAA75492 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

The sequence AAH02883 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

The sequence AAO15305 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

The sequence BAG35905 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

The sequence EAW95070 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_020104	145	T → M. Corresponds to variant dbSNP:rs2235541Ensembl.	1
Natural variantⁱVAR_033850	324	V → I. Corresponds to variant dbSNP:rs520713Ensembl.	1
Natural variantⁱVAR_033851	516	A → V. Corresponds to variant dbSNP:rs550252Ensembl.	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK313079 mRNA Translation: BAG35905.1 Different initiation. DA333869 mRNA No translation available. AL031295 Genomic DNA No translation available. CH471134 Genomic DNA Translation: EAW95070.1 Different initiation. L47345 mRNA Translation: AAA75492.1 Different initiation. BC002883 mRNA Translation: AAH02883.1 Different initiation. AF116729 mRNA Translation: AAO15305.1 Different initiation.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS239.2
PIRⁱ	JC4636
NCBI Reference Sequences More...RefSeqⁱ	NP_003189.2, NM_003198.2
UniGeneⁱ	Hs.15535

Genome annotation databases

Ensemblⁱ	ENST00000418390; ENSP00000395574; ENSG00000011007 ENST00000613537; ENSP00000484196; ENSG00000011007
GeneIDⁱ	6924
KEGGⁱ	hsa:6924
UCSC genome browser More...UCSCⁱ	uc001bho.4 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q14241	Elongin-A		HUMAN		772	UniRef100_Q14241

Protein	Similar proteins		Species	Score	Length	Source
Q14241	Elongin-A		HUMAN		772	UniRef90_Q14241
Uncharacterized protein		CALJA		812
Uncharacterized protein		MACMU		803
Uncharacterized protein		PAPAN		801
Uncharacterized protein		CERAT		800
+29

Protein	Similar proteins		Species	Score	Length	Source
Q14241	Elongin-A		RAT		773	UniRef50_Q14241
Elongin-A		MOUSE		773
Elongin-A		HUMAN		772
Uncharacterized protein		CALJA		812
Uncharacterized protein		MACMU		803
+144

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK313079 mRNA Translation: BAG35905.1 Different initiation. DA333869 mRNA No translation available. AL031295 Genomic DNA No translation available. CH471134 Genomic DNA Translation: EAW95070.1 Different initiation. L47345 mRNA Translation: AAA75492.1 Different initiation. BC002883 mRNA Translation: AAH02883.1 Different initiation. AF116729 mRNA Translation: AAO15305.1 Different initiation.
CCDSⁱ	CCDS239.2
PIRⁱ	JC4636
RefSeqⁱ	NP_003189.2, NM_003198.2
UniGeneⁱ	Hs.15535

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	4HFX	X-ray	2.54	A/B/C/D	597-682	[»]
ProteinModelPortalⁱ	Q14241
SMRⁱ	Q14241
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	112786, 59 interactors
IntActⁱ	Q14241, 56 interactors
MINTⁱ	Q14241
STRINGⁱ	9606.ENSP00000395574

PTM databases

iPTMnetⁱ	Q14241
PhosphoSitePlusⁱ	Q14241

Polymorphism and mutation databases

BioMutaⁱ	TCEB3
DMDMⁱ	294862430

Proteomic databases

EPDⁱ	Q14241
MaxQBⁱ	Q14241
PaxDbⁱ	Q14241
PeptideAtlasⁱ	Q14241
PRIDEⁱ	Q14241
ProteomicsDBⁱ	59938

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	6924
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000418390; ENSP00000395574; ENSG00000011007 ENST00000613537; ENSP00000484196; ENSG00000011007
GeneIDⁱ	6924
KEGGⁱ	hsa:6924
UCSCⁱ	uc001bho.4 human

Organism-specific databases

CTDⁱ	6924
DisGeNETⁱ	6924
EuPathDBⁱ	HostDB:ENSG00000011007.12
GeneCardsⁱ	ELOA
H-InvDBⁱ	HIX0000251
HGNCⁱ	HGNC:11620 ELOA
HPAⁱ	HPA005910
MIMⁱ	600786 gene
neXtProtⁱ	NX_Q14241
OpenTargetsⁱ	ENSG00000011007
PharmGKBⁱ	PA36379
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2821 Eukaryota ENOG4110PG3 LUCA
GeneTreeⁱ	ENSGT00390000002428
HOGENOMⁱ	HOG000059565
HOVERGENⁱ	HBG051467
InParanoidⁱ	Q14241
KOⁱ	K15076
OMAⁱ	HLQETGI
OrthoDBⁱ	EOG091G0D2G
PhylomeDBⁱ	Q14241
TreeFamⁱ	TF317259

Enzyme and pathway databases

Reactomeⁱ	R-HSA-112382 Formation of RNA Pol II elongation complex R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation R-HSA-167243 Tat-mediated HIV elongation arrest and recovery R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript R-HSA-167287 HIV elongation arrest and recovery R-HSA-167290 Pausing and recovery of HIV elongation R-HSA-674695 RNA Polymerase II Pre-transcription Events R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes R-HSA-75955 RNA Polymerase II Transcription Elongation

Reactomeⁱ

R-HSA-112382 Formation of RNA Pol II elongation complex
R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat
R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat
R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation
R-HSA-167243 Tat-mediated HIV elongation arrest and recovery
R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript
R-HSA-167287 HIV elongation arrest and recovery
R-HSA-167290 Pausing and recovery of HIV elongation
R-HSA-674695 RNA Polymerase II Pre-transcription Events
R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-HSA-75955 RNA Polymerase II Transcription Elongation

Miscellaneous databases

GeneWikiⁱ	TCEB3
GenomeRNAiⁱ	6924
Protein Ontology More...PROⁱ	PR:Q14241
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000011007 Expressed in 240 organ(s), highest expression level in upper lobe of lung
ExpressionAtlasⁱ	Q14241 baseline and differential
Genevisibleⁱ	Q14241 HS

Family and domain databases

Gene3Dⁱ	1.20.930.10, 1 hit
InterProⁱ	View protein in InterPro IPR001810 F-box_dom IPR010684 RNA_pol_II_trans_fac_SIII_A IPR003617 TFIIS/CRSP70_N_sub IPR035441 TFIIS/LEDGF_dom_sf IPR017923 TFIIS_N
Pfamⁱ	View protein in Pfam PF06881 Elongin_A, 1 hit PF08711 Med26, 1 hit
SMARTⁱ	View protein in SMART SM00509 TFS2N, 1 hit
SUPFAMⁱ	SSF47676 SSF47676, 1 hit
PROSITEⁱ	View protein in PROSITE PS50181 FBOX, 1 hit PS51319 TFIIS_N, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ELOA1_HUMAN
Accessionⁱ	Q14241Primary (citable) accession number: Q14241 Secondary accession number(s): B2R7Q8, Q8IXH1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 11, 2003
	Last sequence update:	April 20, 2010
	Last modified:	November 7, 2018
	This is version 176 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

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UniProtKB - Q14241 (ELOA1_HUMAN)

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Elongin-A

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Extracellular region or secreted

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ