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Entry version 145 (29 Sep 2021)
Sequence version 2 (25 Nov 2008)
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Protein

Protein FAM53B

Gene

FAM53B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processWnt signaling pathway

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q14153

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM53BCurated
Alternative name(s):
Protein simplet1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM53BImported
Synonyms:KIAA01401 Publication, SMP1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28968, FAM53B

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q14153

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000189319

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
9679

Open Targets

More...
OpenTargetsi
ENSG00000189319

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134957918

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q14153, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM53B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
215273981

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001895441 – 422Protein FAM53BAdd BLAST422

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei118PhosphoserineCombined sources1
Modified residuei167PhosphoserineCombined sources1
Modified residuei169PhosphoserineCombined sources1
Modified residuei179PhosphoserineCombined sources1
Modified residuei212PhosphoserineBy similarity1
Modified residuei268PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q14153

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q14153

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q14153

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q14153

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q14153

PeptideAtlas

More...
PeptideAtlasi
Q14153

PRoteomics IDEntifications database

More...
PRIDEi
Q14153

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
59855 [Q14153-1]
59856 [Q14153-2]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q14153, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q14153

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q14153

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in skeletal muscle, kidney, spleen, thyroid, testis, ovary, small intestine, colon and peripheral blood.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000189319, Expressed in ventricular zone and 244 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q14153, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000189319, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
115033, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q14153, 9 interactors

Molecular INTeraction database

More...
MINTi
Q14153

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000338532

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q14153, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni245 – 269DisorderedSequence analysisAdd BLAST25

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi281 – 284Nuclear localization signalBy similarity4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM53 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQM7, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063371

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_054215_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q14153

Identification of Orthologs from Complete Genome Data

More...
OMAi
FHHRFGG

Database of Orthologous Groups

More...
OrthoDBi
1614405at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q14153

TreeFam database of animal gene trees

More...
TreeFami
TF332095

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029356, FAM53

The PANTHER Classification System

More...
PANTHERi
PTHR28567, PTHR28567, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15242, FAM53, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q14153-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVMVLSESLS TRGADSIACG TFSRELHTPK KMSQGPTLFS CGIMENDRWR
60 70 80 90 100
DLDRKCPLQI DQPSTSIWEC LPEKDSSLWH REAVTACAVT SLIKDLSISD
110 120 130 140 150
HNGNPSAPPS KRQCRSLSFS DEMSSCRTSW RPLGSKVWTP VEKRRCYSGG
160 170 180 190 200
SVQRYSNGFS TMQRSSSFSL PSRANVLSSP CDQAGLHHRF GGQPCQGVPG
210 220 230 240 250
SAPCGQAGDT WSPDLHPVGG GRLDLQRSLS CSHEQFSFVE YCPPSANSTP
260 270 280 290 300
ASTPELARRS SGLSRSRSQP CVLNDKKVGV KRRRPEEVQE QRPSLDLAKM
310 320 330 340 350
AQNCQTFSSL SCLSAGTEDC GPQSPFARHV SNTRAWTALL SASGPGGRTP
360 370 380 390 400
AGTPVPEPLP PSFDDHLACQ EDLSCEESDS CALDEDCGRR AEPAAAWRDR
410 420
GAPGNSLCSL DGELDIEQIE KN
Length:422
Mass (Da):45,768
Last modified:November 25, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7F7768093408D791
GO
Isoform 2 (identifier: Q14153-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     303-305: NCQ → IAP
     306-422: Missing.

Show »
Length:305
Mass (Da):33,446
Checksum:iD1743235823004B7
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA09489 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti368A → V in BAA09489 (PubMed:8590280).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_009932303 – 305NCQ → IAP in isoform 2. 1 Publication3
Alternative sequenceiVSP_009933306 – 422Missing in isoform 2. 1 PublicationAdd BLAST117

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D50930 mRNA Translation: BAA09489.2 Different initiation.
AK127343 mRNA Translation: BAG54488.1
AC068896 Genomic DNA No translation available.
AL513190 Genomic DNA No translation available.
CH471066 Genomic DNA Translation: EAW49259.1
CH471066 Genomic DNA Translation: EAW49260.1
CH471066 Genomic DNA Translation: EAW49261.1
CH471066 Genomic DNA Translation: EAW49262.1
BC031654 mRNA Translation: AAH31654.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS7641.1 [Q14153-1]

NCBI Reference Sequences

More...
RefSeqi
NP_055476.3, NM_014661.3 [Q14153-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000280780; ENSP00000280780; ENSG00000189319 [Q14153-2]
ENST00000337318; ENSP00000338532; ENSG00000189319 [Q14153-1]
ENST00000392754; ENSP00000376509; ENSG00000189319 [Q14153-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9679

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9679

UCSC genome browser

More...
UCSCi
uc001lhv.2, human [Q14153-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50930 mRNA Translation: BAA09489.2 Different initiation.
AK127343 mRNA Translation: BAG54488.1
AC068896 Genomic DNA No translation available.
AL513190 Genomic DNA No translation available.
CH471066 Genomic DNA Translation: EAW49259.1
CH471066 Genomic DNA Translation: EAW49260.1
CH471066 Genomic DNA Translation: EAW49261.1
CH471066 Genomic DNA Translation: EAW49262.1
BC031654 mRNA Translation: AAH31654.1
CCDSiCCDS7641.1 [Q14153-1]
RefSeqiNP_055476.3, NM_014661.3 [Q14153-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi115033, 7 interactors
IntActiQ14153, 9 interactors
MINTiQ14153
STRINGi9606.ENSP00000338532

PTM databases

GlyGeniQ14153, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ14153
PhosphoSitePlusiQ14153

Genetic variation databases

BioMutaiFAM53B
DMDMi215273981

Proteomic databases

EPDiQ14153
jPOSTiQ14153
MassIVEiQ14153
MaxQBiQ14153
PaxDbiQ14153
PeptideAtlasiQ14153
PRIDEiQ14153
ProteomicsDBi59855 [Q14153-1]
59856 [Q14153-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
48489, 45 antibodies

The DNASU plasmid repository

More...
DNASUi
9679

Genome annotation databases

EnsembliENST00000280780; ENSP00000280780; ENSG00000189319 [Q14153-2]
ENST00000337318; ENSP00000338532; ENSG00000189319 [Q14153-1]
ENST00000392754; ENSP00000376509; ENSG00000189319 [Q14153-1]
GeneIDi9679
KEGGihsa:9679
UCSCiuc001lhv.2, human [Q14153-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9679
DisGeNETi9679

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM53B
HGNCiHGNC:28968, FAM53B
HPAiENSG00000189319, Low tissue specificity
neXtProtiNX_Q14153
OpenTargetsiENSG00000189319
PharmGKBiPA134957918
VEuPathDBiHostDB:ENSG00000189319

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QQM7, Eukaryota
GeneTreeiENSGT00530000063371
HOGENOMiCLU_054215_2_0_1
InParanoidiQ14153
OMAiFHHRFGG
OrthoDBi1614405at2759
PhylomeDBiQ14153
TreeFamiTF332095

Enzyme and pathway databases

PathwayCommonsiQ14153

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
9679, 4 hits in 1021 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM53B, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9679
PharosiQ14153, Tdark

Protein Ontology

More...
PROi
PR:Q14153
RNActiQ14153, protein

Gene expression databases

BgeeiENSG00000189319, Expressed in ventricular zone and 244 other tissues
GenevisibleiQ14153, HS

Family and domain databases

InterProiView protein in InterPro
IPR029356, FAM53
PANTHERiPTHR28567, PTHR28567, 1 hit
PfamiView protein in Pfam
PF15242, FAM53, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFA53B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q14153
Secondary accession number(s): D3DRF1
, Q5VUW1, Q5VUW2, Q8N5S6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 25, 2008
Last modified: September 29, 2021
This is version 145 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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