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Entry version 164 (31 Jul 2019)
Sequence version 2 (02 Nov 2010)
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Protein

Probable ATP-dependent RNA helicase DHX34

Gene

DHX34

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable ATP-binding RNA helicase.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi185 – 192ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicase, Hydrolase, RNA-binding
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable ATP-dependent RNA helicase DHX34 (EC:3.6.4.13)
Alternative name(s):
DEAH box protein 34
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DHX34
Synonyms:DDX34, KIAA0134
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:16719 DHX34

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615475 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q14147

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000134815

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA27221

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
DHX34

Domain mapping of disease mutations (DMDM)

More...
DMDMi
311033371

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000551661 – 1143Probable ATP-dependent RNA helicase DHX34Add BLAST1143

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei749PhosphoserineCombined sources1
Modified residuei750PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q14147

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q14147

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q14147

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q14147

PeptideAtlas

More...
PeptideAtlasi
Q14147

PRoteomics IDEntifications database

More...
PRIDEi
Q14147

ProteomicsDB human proteome resource

More...
ProteomicsDBi
59851

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q14147

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q14147

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000134815 Expressed in 184 organ(s), highest expression level in blood

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q14147 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q14147 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA042159
HPA043558

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115056, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q14147, 7 interactors

Molecular INTeraction database

More...
MINTi
Q14147

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000331907

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini172 – 332Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST161
Domaini368 – 536Helicase C-terminalPROSITE-ProRule annotationAdd BLAST169

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi279 – 282DEAH box4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0922 Eukaryota
COG1643 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158721

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000232193

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q14147

KEGG Orthology (KO)

More...
KOi
K20101

Identification of Orthologs from Complete Genome Data

More...
OMAi
YASHTQR

Database of Orthologous Groups

More...
OrthoDBi
278674at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q14147

TreeFam database of animal gene trees

More...
TreeFami
TF313217

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011709 DUF1605
IPR007502 Helicase-assoc_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04408 HA2, 1 hit
PF00271 Helicase_C, 1 hit
PF07717 OB_NTP_bind, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487 DEXDc, 1 hit
SM00847 HA2, 1 hit
SM00490 HELICc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q14147-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPPRTREGR DRRDHHRAPS EEEALEKWDW NCPETRRLLE DAFFREEDYI
60 70 80 90 100
RQGSEECQKF WTFFERLQRF QNLKTSRKEE KDPGQPKHSI PALADLPRTY
110 120 130 140 150
DPRYRINLSV LGPATRGSQG LGRHLPAERV AEFRRALLHY LDFGQKQAFG
160 170 180 190 200
RLAKLQRERA ALPIAQYGNR ILQTLKEHQV VVVAGDTGCG KSTQVPQYLL
210 220 230 240 250
AAGFSHVACT QPRRIACISL AKRVGFESLS QYGSQVGYQI RFESTRSAAT
260 270 280 290 300
KIVFLTVGLL LRQIQREPSL PQYEVLIVDE VHERHLHNDF LLGVLQRLLP
310 320 330 340 350
TRPDLKVILM SATINISLFS SYFSNAPVVQ VPGRLFPITV VYQPQEAEPT
360 370 380 390 400
TSKSEKLDPR PFLRVLESID HKYPPEERGD LLVFLSGMAE ISAVLEAAQT
410 420 430 440 450
YASHTQRWVV LPLHSALSVA DQDKVFDVAP PGVRKCILST NIAETSVTID
460 470 480 490 500
GIRFVVDSGK VKEMSYDPQA KLQRLQEFWI SQASAEQRKG RAGRTGPGVC
510 520 530 540 550
FRLYAESDYD AFAPYPVPEI RRVALDSLVL QMKSMSVGDP RTFPFIEPPP
560 570 580 590 600
PASLETAILY LRDQGALDSS EALTPIGSLL AQLPVDVVIG KMLILGSMFS
610 620 630 640 650
LVEPVLTIAA ALSVQSPFTR SAQSSPECAA ARRPLESDQG DPFTLFNVFN
660 670 680 690 700
AWVQVKSERS RNSRKWCRRR GIEEHRLYEM ANLRRQFKEL LEDHGLLAGA
710 720 730 740 750
QAAQVGDSYS RLQQRRERRA LHQLKRQHEE GAGRRRKVLR LQEEQDGGSS
760 770 780 790 800
DEDRAGPAPP GASDGVDIQD VKFKLRHDLA QLQAAASSAQ DLSREQLALL
810 820 830 840 850
KLVLGRGLYP QLAVPDAFNS SRKDSDQIFH TQAKQGAVLH PTCVFAGSPE
860 870 880 890 900
VLHAQELEAS NCDGSRDDKD KMSSKHQLLS FVSLLETNKP YLVNCVRIPA
910 920 930 940 950
LQSLLLFSRS LDTNGDCSRL VADGWLELQL ADSESAIRLL AASLRLRARW
960 970 980 990 1000
ESALDRQLAH QAQQQLEEEE EDTPVSPKEV ATLSKELLQF TASKIPYSLR
1010 1020 1030 1040 1050
RLTGLEVQNM YVGPQTIPAT PHLPGLFGSS TLSPHPTKGG YAVTDFLTYN
1060 1070 1080 1090 1100
CLTNDTDLYS DCLRTFWTCP HCGLHAPLTP LERIAHENTC PQAPQDGPPG
1110 1120 1130 1140
AEEAALETLQ KTSVLQRPYH CEACGKDFLF TPTEVLRHRK QHV
Length:1,143
Mass (Da):128,120
Last modified:November 2, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4081CAC2D9B4B840
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C504H7C504_HUMAN
Probable ATP-dependent RNA helicase...
DHX34
272Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA09483 differs from that shown. Aberrant splicing.Curated
The sequence BAG60050 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05724117R → W. Corresponds to variant dbSNP:rs12984558Ensembl.1
Natural variantiVAR_057242117G → D. Corresponds to variant dbSNP:rs8113564Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D50924 mRNA Translation: BAA09483.2 Sequence problems.
AC008754 Genomic DNA No translation available.
AK297692 mRNA Translation: BAG60050.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12700.1

NCBI Reference Sequences

More...
RefSeqi
NP_055496.2, NM_014681.5
XP_005259500.1, XM_005259443.3
XP_011525852.1, XM_011527550.2
XP_011525853.1, XM_011527551.2
XP_016883013.1, XM_017027524.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000328771; ENSP00000331907; ENSG00000134815

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9704

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9704

UCSC genome browser

More...
UCSCi
uc010xyn.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50924 mRNA Translation: BAA09483.2 Sequence problems.
AC008754 Genomic DNA No translation available.
AK297692 mRNA Translation: BAG60050.1 Different initiation.
CCDSiCCDS12700.1
RefSeqiNP_055496.2, NM_014681.5
XP_005259500.1, XM_005259443.3
XP_011525852.1, XM_011527550.2
XP_011525853.1, XM_011527551.2
XP_016883013.1, XM_017027524.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi115056, 11 interactors
IntActiQ14147, 7 interactors
MINTiQ14147
STRINGi9606.ENSP00000331907

PTM databases

iPTMnetiQ14147
PhosphoSitePlusiQ14147

Polymorphism and mutation databases

BioMutaiDHX34
DMDMi311033371

Proteomic databases

EPDiQ14147
jPOSTiQ14147
MaxQBiQ14147
PaxDbiQ14147
PeptideAtlasiQ14147
PRIDEiQ14147
ProteomicsDBi59851

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
9704
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000328771; ENSP00000331907; ENSG00000134815
GeneIDi9704
KEGGihsa:9704
UCSCiuc010xyn.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9704

GeneCards: human genes, protein and diseases

More...
GeneCardsi
DHX34
HGNCiHGNC:16719 DHX34
HPAiHPA042159
HPA043558
MIMi615475 gene
neXtProtiNX_Q14147
OpenTargetsiENSG00000134815
PharmGKBiPA27221

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0922 Eukaryota
COG1643 LUCA
GeneTreeiENSGT00940000158721
HOGENOMiHOG000232193
InParanoidiQ14147
KOiK20101
OMAiYASHTQR
OrthoDBi278674at2759
PhylomeDBiQ14147
TreeFamiTF313217

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
DHX34 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9704

Protein Ontology

More...
PROi
PR:Q14147

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000134815 Expressed in 184 organ(s), highest expression level in blood
ExpressionAtlasiQ14147 baseline and differential
GenevisibleiQ14147 HS

Family and domain databases

InterProiView protein in InterPro
IPR011709 DUF1605
IPR007502 Helicase-assoc_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF04408 HA2, 1 hit
PF00271 Helicase_C, 1 hit
PF07717 OB_NTP_bind, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00847 HA2, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDHX34_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q14147
Secondary accession number(s): B4DMY8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 2, 2010
Last modified: July 31, 2019
This is version 164 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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