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UniProtKB - Q13875 (MOBP_HUMAN)

Entry version 138 (07 Apr 2021)
Sequence version 2 (20 Mar 2007)
Previous versions | rss
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Protein

Myelin-associated oligodendrocyte basic protein

Gene

MOBP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q13875

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-8986944, Transcriptional Regulation by MECP2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Myelin-associated oligodendrocyte basic protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MOBP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:7189, MOBP

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		600948, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q13875

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000168314.17

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		4336

Open Targets

More...OpenTargetsi		ENSG00000168314

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA30899

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q13875, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MOBP

Domain mapping of disease mutations (DMDM)

More...DMDMi		134034171

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002810251 – 183Myelin-associated oligodendrocyte basic proteinAdd BLAST183

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei99PhosphoserineBy similarity1
Modified residuei109PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q13875

PeptideAtlas

More...PeptideAtlasi		Q13875

PRoteomics IDEntifications database

More...PRIDEi		Q13875

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		33825
59706 [Q13875-1]
59707 [Q13875-2]
59708 [Q13875-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q13875

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q13875

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000168314, Expressed in inferior vagus X ganglion and 167 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q13875, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q13875, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000168314, Tissue enriched (brain)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		110479, 22 interactors

Protein interaction database and analysis system

More...IntActi		Q13875, 16 interactors

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q13875, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati97 – 106110
Repeati107 – 116210
Repeati117 – 126310
Repeati127 – 136410

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni97 – 1364 X 10 AA tandem repeats of P-R-S-P-P-R-S-E-R-QAdd BLAST40

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi77 – 168Pro-richAdd BLAST92

Keywords - Domaini

Repeat

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00950000183138

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_2855470_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q13875

Identification of Orthologs from Complete Genome Data

More...OMAi		CACQRTS

Database of Orthologous Groups

More...OrthoDBi		492485at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q13875

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR041282, FYVE_2
IPR013083, Znf_RING/FYVE/PHD

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02318, FYVE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q13875-1) [UniParc]FASTAAdd to basket
Also known as: OPRP2

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSQKPAKEGP RLSKNQKYSE HFSIHCCPPF TFLNSKKEIV DRKYSICKSG 
        60         70         80         90        100
CFYQKKEEDW ICCACQKTRT SRRAKSPQRP KQQPAAPPAV VRAPAKPRSP 
       110        120        130        140        150
PRSERQPRSP PRSERQPRSP PRSERQPRSP PRSERQPRPR PEVRPPPAKQ 
       160        170        180 
RPPQKSKQQP RSSPLRGPGA SRGGSPVKAS RFW
Length:183
Mass (Da):20,959
Last modified:March 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i81831413BCC6A041
GO
Isoform 2 (identifier: Q13875-2) [UniParc]FASTAAdd to basket
Also known as: OPRP1

The sequence of this isoform differs from the canonical sequence as follows:
     183-183: Missing.

Show »
Length:182
Mass (Da):20,773
Checksum:iE31413BCC6A041B5
GO
Isoform 3 (identifier: Q13875-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     70-81: TSRRAKSPQRPK → LKRKIRPTPKKK
     82-183: Missing.

Show »
Length:81
Mass (Da):9,614
Checksum:i741E059219155AAF
GO
Isoform 4 (identifier: Q13875-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     68-68: T → TSSCQRRLSSRGEPWLPPPASFGPL
     183-183: Missing.

Show »
Length:206
Mass (Da):23,381
Checksum:i9B33699136F2E7D7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JLT8C9JLT8_HUMAN
Myelin-associated oligodendrocyte b...
MOBP
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JAR7C9JAR7_HUMAN
Myelin-associated oligodendrocyte b...
MOBP
58Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti28P → R in AAH75796 (PubMed:15489334).Curated1
Sequence conflicti40V → E in AK127034 (PubMed:14702039).Curated1
Sequence conflicti76S → P in BAA05660 (PubMed:7989345).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05515268T → TSSCQRRLSSRGEPWLPPPA SFGPL in isoform 4. 1 Publication1
Alternative sequenceiVSP_02393370 – 81TSRRA…PQRPK → LKRKIRPTPKKK in isoform 3. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_02393482 – 183Missing in isoform 3. 1 PublicationAdd BLAST102
Alternative sequenceiVSP_023935183Missing in isoform 2 and isoform 4. 2 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
D28113 mRNA Translation: BAA05659.1
D28114 mRNA Translation: BAA05660.1
AK127034 mRNA No translation available.
AK290187 mRNA Translation: BAF82876.1
AC092058 Genomic DNA No translation available.
CH471055 Genomic DNA Translation: EAW64588.1
CH471055 Genomic DNA Translation: EAW64592.1
BC022471 mRNA Translation: AAH22471.1
BC075796 mRNA Translation: AAH75796.1
BC119694 mRNA Translation: AAI19695.1
BC119695 mRNA Translation: AAI19696.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS2687.1 [Q13875-3]
CCDS2688.1 [Q13875-1]
CCDS63598.1 [Q13875-4]

Protein sequence database of the Protein Information Resource

More...PIRi		C55663

NCBI Reference Sequences

More...RefSeqi		NP_001265251.1, NM_001278322.1 [Q13875-4]
NP_001265252.1, NM_001278323.1 [Q13875-1]
NP_891980.1, NM_182935.3 [Q13875-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000311042; ENSP00000312293; ENSG00000168314 [Q13875-4]
ENST00000383754; ENSP00000373261; ENSG00000168314 [Q13875-3]
ENST00000415443; ENSP00000388148; ENSG00000168314 [Q13875-3]
ENST00000420739; ENSP00000400491; ENSG00000168314 [Q13875-1]
ENST00000424090; ENSP00000389055; ENSG00000168314 [Q13875-1]
ENST00000428261; ENSP00000401312; ENSG00000168314 [Q13875-3]
ENST00000441980; ENSP00000388827; ENSG00000168314 [Q13875-1]
ENST00000442631; ENSP00000413771; ENSG00000168314 [Q13875-2]
ENST00000447324; ENSP00000409730; ENSG00000168314 [Q13875-3]
ENST00000452959; ENSP00000405549; ENSG00000168314 [Q13875-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		4336

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:4336

UCSC genome browser

More...UCSCi		uc003cju.5, human [Q13875-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D28113 mRNA Translation: BAA05659.1
D28114 mRNA Translation: BAA05660.1
AK127034 mRNA No translation available.
AK290187 mRNA Translation: BAF82876.1
AC092058 Genomic DNA No translation available.
CH471055 Genomic DNA Translation: EAW64588.1
CH471055 Genomic DNA Translation: EAW64592.1
BC022471 mRNA Translation: AAH22471.1
BC075796 mRNA Translation: AAH75796.1
BC119694 mRNA Translation: AAI19695.1
BC119695 mRNA Translation: AAI19696.1
CCDSiCCDS2687.1 [Q13875-3]
CCDS2688.1 [Q13875-1]
CCDS63598.1 [Q13875-4]
PIRiC55663
RefSeqiNP_001265251.1, NM_001278322.1 [Q13875-4]
NP_001265252.1, NM_001278323.1 [Q13875-1]
NP_891980.1, NM_182935.3 [Q13875-3]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi110479, 22 interactors
IntActiQ13875, 16 interactors

PTM databases

iPTMnetiQ13875
PhosphoSitePlusiQ13875

Genetic variation databases

BioMutaiMOBP
DMDMi134034171

Proteomic databases

MassIVEiQ13875
PeptideAtlasiQ13875
PRIDEiQ13875
ProteomicsDBi33825
59706 [Q13875-1]
59707 [Q13875-2]
59708 [Q13875-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		28962, 187 antibodies

The DNASU plasmid repository

More...DNASUi		4336

Genome annotation databases

EnsembliENST00000311042; ENSP00000312293; ENSG00000168314 [Q13875-4]
ENST00000383754; ENSP00000373261; ENSG00000168314 [Q13875-3]
ENST00000415443; ENSP00000388148; ENSG00000168314 [Q13875-3]
ENST00000420739; ENSP00000400491; ENSG00000168314 [Q13875-1]
ENST00000424090; ENSP00000389055; ENSG00000168314 [Q13875-1]
ENST00000428261; ENSP00000401312; ENSG00000168314 [Q13875-3]
ENST00000441980; ENSP00000388827; ENSG00000168314 [Q13875-1]
ENST00000442631; ENSP00000413771; ENSG00000168314 [Q13875-2]
ENST00000447324; ENSP00000409730; ENSG00000168314 [Q13875-3]
ENST00000452959; ENSP00000405549; ENSG00000168314 [Q13875-3]
GeneIDi4336
KEGGihsa:4336
UCSCiuc003cju.5, human [Q13875-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		4336
DisGeNETi4336

GeneCards: human genes, protein and diseases

More...GeneCardsi		MOBP
HGNCiHGNC:7189, MOBP
HPAiENSG00000168314, Tissue enriched (brain)
MIMi600948, gene
neXtProtiNX_Q13875
OpenTargetsiENSG00000168314
PharmGKBiPA30899
VEuPathDBiHostDB:ENSG00000168314.17

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT00950000183138
HOGENOMiCLU_2855470_0_0_1
InParanoidiQ13875
OMAiCACQRTS
OrthoDBi492485at2759
PhylomeDBiQ13875

Enzyme and pathway databases

PathwayCommonsiQ13875
ReactomeiR-HSA-8986944, Transcriptional Regulation by MECP2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		4336, 4 hits in 990 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		MOBP, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		4336
PharosiQ13875, Tbio

Protein Ontology

More...PROi		PR:Q13875
RNActiQ13875, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000168314, Expressed in inferior vagus X ganglion and 167 other tissues
ExpressionAtlasiQ13875, baseline and differential
GenevisibleiQ13875, HS

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR041282, FYVE_2
IPR013083, Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF02318, FYVE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMOBP_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q13875
Secondary accession number(s): A8K2C2
, G5E945, Q13874, Q6DHZ6, Q8TBJ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 20, 2007
Last modified: April 7, 2021
This is version 138 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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