UniProtKB - Q13614 (MTMR2_HUMAN)
Myotubularin-related protein 2
MTMR2
Functioni
Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (PubMed:11733541, PubMed:12668758, PubMed:21372139, PubMed:14690594).
Binds phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (By similarity).
Stabilizes SBF2/MTMR13 at the membranes (By similarity).
Specifically in peripheral nerves, stabilizes SBF2/MTMR13 protein (By similarity).
By similarity4 PublicationsCatalytic activityi
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate4 PublicationsEC:3.1.3.644 Publications
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate3 PublicationsEC:3.1.3.953 Publications
Activity regulationi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 417 | Phosphocysteine intermediate2 Publications | 1 | |
Binding sitei | 463 | Substrate1 Publication | 1 |
GO - Molecular functioni
- identical protein binding Source: Ensembl
- phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity Source: UniProtKB
- phosphatidylinositol-3-phosphatase activity Source: UniProtKB
- protein tyrosine/serine/threonine phosphatase activity Source: UniProtKB
- protein tyrosine phosphatase activity Source: InterPro
GO - Biological processi
- dendritic spine maintenance Source: BHF-UCL
- inositol phosphate dephosphorylation Source: Ensembl
- myelin assembly Source: Ensembl
- negative regulation of endocytosis Source: BHF-UCL
- negative regulation of excitatory postsynaptic potential Source: BHF-UCL
- negative regulation of myelination Source: Ensembl
- negative regulation of receptor catabolic process Source: BHF-UCL
- negative regulation of receptor internalization Source: BHF-UCL
- neuron development Source: Ensembl
- phosphatidylinositol biosynthetic process Source: Reactome
- phosphatidylinositol dephosphorylation Source: UniProtKB
- positive regulation of early endosome to late endosome transport Source: BHF-UCL
- protein dephosphorylation Source: UniProtKB
- regulation of phosphatidylinositol dephosphorylation Source: UniProtKB
Keywordsi
Molecular function | Hydrolase |
Biological process | Lipid metabolism |
Enzyme and pathway databases
BRENDAi | 3.1.3.64, 2681 3.1.3.95, 2681 |
PathwayCommonsi | Q13614 |
Reactomei | R-HSA-1483248, Synthesis of PIPs at the ER membrane R-HSA-1660499, Synthesis of PIPs at the plasma membrane R-HSA-1660516, Synthesis of PIPs at the early endosome membrane R-HSA-1660517, Synthesis of PIPs at the late endosome membrane |
SignaLinki | Q13614 |
Chemistry databases
SwissLipidsi | SLP:000001135 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:7450, MTMR2 |
MIMi | 603557, gene |
neXtProti | NX_Q13614 |
VEuPathDBi | HostDB:ENSG00000087053 |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm 3 Publications
Endosome
- Early endosome membrane 2 Publications; Peripheral membrane protein 2 Publications
- Endosome membrane By similarity; Peripheral membrane protein Curated
Other locations
- perinuclear region 1 Publication
- axon By similarity
Note: Partly associated with membranes (PubMed:12668758, PubMed:15998640, PubMed:21372139). Localizes to vacuoles in hypo-osmotic conditions (By similarity).By similarity3 Publications
Cytosol
- cytosol Source: UniProtKB
Endosome
- early endosome membrane Source: UniProtKB-SubCell
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
Nucleus
- nucleus Source: UniProtKB
Plasma Membrane
- synaptic membrane Source: BHF-UCL
Other locations
- axon Source: BHF-UCL
- cytoplasm Source: UniProtKB
- dendrite Source: BHF-UCL
- dendritic spine Source: BHF-UCL
- intracellular membrane-bounded organelle Source: HPA
- perinuclear region of cytoplasm Source: UniProtKB-SubCell
- postsynaptic density Source: BHF-UCL
- synaptic vesicle Source: BHF-UCL
- vacuolar membrane Source: Ensembl
Keywords - Cellular componenti
Cell projection, Cytoplasm, Endosome, MembranePathology & Biotechi
Involvement in diseasei
Charcot-Marie-Tooth disease 4B1 (CMT4B1)2 Publications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_047947 | 283 | R → W in CMT4B1. 1 PublicationCorresponds to variant dbSNP:rs1590983932EnsemblClinVar. | 1 |
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 417 | C → S: Loss of activity. 2 Publications | 1 | |
Mutagenesisi | 419 | D → A: No effect. 1 Publication | 1 | |
Mutagenesisi | 422 | D → A: Loss of activity. 1 Publication | 1 | |
Mutagenesisi | 589 – 643 | Missing : Loss of homodimerization and interaction with SBF1. 1 PublicationAdd BLAST | 55 | |
Mutagenesisi | 607 | L → Y: Reduces homodimerization and interaction with SBF1. 1 Publication | 1 |
Keywords - Diseasei
Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, NeuropathyOrganism-specific databases
DisGeNETi | 8898 |
GeneReviewsi | MTMR2 |
MalaCardsi | MTMR2 |
MIMi | 601382, phenotype |
OpenTargetsi | ENSG00000087053 |
Orphaneti | 99955, Charcot-Marie-Tooth disease type 4B1 |
PharmGKBi | PA31253 |
Miscellaneous databases
Pharosi | Q13614, Tbio |
Genetic variation databases
BioMutai | MTMR2 |
DMDMi | 212276520 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000094934 | 1 – 643 | Myotubularin-related protein 2Add BLAST | 643 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 6 | PhosphoserineBy similarity | 1 | |
Modified residuei | 9 | PhosphoserineBy similarity | 1 | |
Modified residuei | 58 | PhosphoserineCombined sources1 Publication | 1 |
Post-translational modificationi
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q13614 |
jPOSTi | Q13614 |
MassIVEi | Q13614 |
MaxQBi | Q13614 |
PaxDbi | Q13614 |
PeptideAtlasi | Q13614 |
PRIDEi | Q13614 |
ProteomicsDBi | 1592 59600 [Q13614-1] |
PTM databases
DEPODi | MTMR2 |
GlyGeni | Q13614, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q13614 |
MetOSitei | Q13614 |
PhosphoSitePlusi | Q13614 |
SwissPalmi | Q13614 |
Expressioni
Gene expression databases
Bgeei | ENSG00000087053, Expressed in testis and 237 other tissues |
ExpressionAtlasi | Q13614, baseline and differential |
Genevisiblei | Q13614, HS |
Organism-specific databases
HPAi | ENSG00000087053, Low tissue specificity |
Interactioni
Subunit structurei
Binary interactionsi
Q13614
With | #Exp. | IntAct |
---|---|---|
NEFL [P07196] | 2 | EBI-475631,EBI-475646 |
GO - Molecular functioni
- identical protein binding Source: Ensembl
Protein-protein interaction databases
BioGRIDi | 114415, 55 interactors |
IntActi | Q13614, 12 interactors |
MINTi | Q13614 |
STRINGi | 9606.ENSP00000345752 |
Miscellaneous databases
RNActi | Q13614, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q13614 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q13614 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 68 – 139 | GRAMSequence analysisAdd BLAST | 72 | |
Domaini | 205 – 580 | Myotubularin phosphatasePROSITE-ProRule annotationAdd BLAST | 376 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 56 | DisorderedSequence analysisAdd BLAST | 56 | |
Regioni | 330 – 333 | Substrate binding1 Publication | 4 | |
Regioni | 355 – 356 | Substrate binding1 Publication | 2 | |
Regioni | 417 – 423 | Substrate binding1 Publication | 7 | |
Regioni | 615 – 643 | DisorderedSequence analysisAdd BLAST | 29 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 593 – 627 | 1 PublicationAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 19 – 56 | Polar residuesSequence analysisAdd BLAST | 38 | |
Compositional biasi | 618 – 643 | Polar residuesSequence analysisAdd BLAST | 26 |
Domaini
Sequence similaritiesi
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | KOG4471, Eukaryota |
GeneTreei | ENSGT00940000153669 |
InParanoidi | Q13614 |
OMAi | ESYAICD |
OrthoDBi | 824298at2759 |
PhylomeDBi | Q13614 |
TreeFami | TF315197 |
Family and domain databases
Gene3Di | 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR004182, GRAM IPR010569, Myotubularin-like_Pase_dom IPR030564, Myotubularin_fam IPR011993, PH-like_dom_sf IPR029021, Prot-tyrosine_phosphatase-like IPR016130, Tyr_Pase_AS IPR003595, Tyr_Pase_cat IPR000387, Tyr_Pase_dom |
PANTHERi | PTHR10807, PTHR10807, 1 hit |
Pfami | View protein in Pfam PF02893, GRAM, 1 hit PF06602, Myotub-related, 1 hit |
SMARTi | View protein in SMART SM00568, GRAM, 1 hit SM00404, PTPc_motif, 1 hit |
SUPFAMi | SSF52799, SSF52799, 1 hit |
PROSITEi | View protein in PROSITE PS51339, PPASE_MYOTUBULARIN, 1 hit PS00383, TYR_PHOSPHATASE_1, 1 hit PS50056, TYR_PHOSPHATASE_2, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 10 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MEKSSSCESL GSQPAAARPP SVDSLSSAST SHSENSVHTK SASVVSSDSI
60 70 80 90 100
STSADNFSPD LRVLRESNKL AEMEEPPLLP GENIKDMAKD VTYICPFTGA
110 120 130 140 150
VRGTLTVTNY RLYFKSMERD PPFVLDASLG VINRVEKIGG ASSRGENSYG
160 170 180 190 200
LETVCKDIRN LRFAHKPEGR TRRSIFENLM KYAFPVSNNL PLFAFEYKEV
210 220 230 240 250
FPENGWKLYD PLLEYRRQGI PNESWRITKI NERYELCDTY PALLVVPANI
260 270 280 290 300
PDEELKRVAS FRSRGRIPVL SWIHPESQAT ITRCSQPMVG VSGKRSKEDE
310 320 330 340 350
KYLQAIMDSN AQSHKIFIFD ARPSVNAVAN KAKGGGYESE DAYQNAELVF
360 370 380 390 400
LDIHNIHVMR ESLRKLKEIV YPNIEETHWL SNLESTHWLE HIKLILAGAL
410 420 430 440 450
RIADKVESGK TSVVVHCSDG WDRTAQLTSL AMLMLDGYYR TIRGFEVLVE
460 470 480 490 500
KEWLSFGHRF QLRVGHGDKN HADADRSPVF LQFIDCVWQM TRQFPTAFEF
510 520 530 540 550
NEYFLITILD HLYSCLFGTF LCNSEQQRGK ENLPKRTVSL WSYINSQLED
560 570 580 590 600
FTNPLYGSYS NHVLYPVASM RHLELWVGYY IRWNPRMKPQ EPIHNRYKEL
610 620 630 640
LAKRAELQKK VEELQREISN RSTSSSERAS SPAQCVTPVQ TVV
Computationally mapped potential isoform sequencesi
There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketC9JEX3 | C9JEX3_HUMAN | Phosphatidylinositol-3,5-bisphospha... | MTMR2 | 556 | Annotation score: | ||
A0A6Q8PGS5 | A0A6Q8PGS5_HUMAN | Phosphatidylinositol-3,5-bisphospha... | MTMR2 | 540 | Annotation score: | ||
A0A6Q8PHL9 | A0A6Q8PHL9_HUMAN | Phosphatidylinositol-3,5-bisphospha... | MTMR2 | 581 | Annotation score: | ||
A0A6Q8PHS7 | A0A6Q8PHS7_HUMAN | Phosphatidylinositol-3,5-bisphospha... | MTMR2 | 527 | Annotation score: | ||
A0A6Q8PGV9 | A0A6Q8PGV9_HUMAN | Myotubularin-related protein 2 | MTMR2 | 225 | Annotation score: | ||
A0A6Q8PFL3 | A0A6Q8PFL3_HUMAN | Myotubularin-related protein 2 | MTMR2 | 89 | Annotation score: | ||
A0A6Q8PF46 | A0A6Q8PF46_HUMAN | Myotubularin-related protein 2 | MTMR2 | 69 | Annotation score: | ||
A0A6Q8PG25 | A0A6Q8PG25_HUMAN | Myotubularin-related protein 2 | MTMR2 | 91 | Annotation score: | ||
A0A6Q8PGT1 | A0A6Q8PGT1_HUMAN | Myotubularin-related protein 2 | MTMR2 | 86 | Annotation score: | ||
A0A6Q8PHC4 | A0A6Q8PHC4_HUMAN | Myotubularin-related protein 2 | MTMR2 | 69 | Annotation score: |
Sequence cautioni
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_047255 | 3 | K → T2 PublicationsCorresponds to variant dbSNP:rs3824874EnsemblClinVar. | 1 | |
Natural variantiVAR_047947 | 283 | R → W in CMT4B1. 1 PublicationCorresponds to variant dbSNP:rs1590983932EnsemblClinVar. | 1 | |
Natural variantiVAR_047256 | 545 | N → S. Corresponds to variant dbSNP:rs558018EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_044933 | 1 – 72 | Missing in isoform 2. 1 PublicationAdd BLAST | 72 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB028996 mRNA Translation: BAA83025.2 Different initiation. AK302940 mRNA Translation: BAG64098.1 AP000870 Genomic DNA No translation available. AP001877 Genomic DNA No translation available. CH471065 Genomic DNA Translation: EAW66971.1 BC052990 mRNA Translation: AAH52990.1 U58033 mRNA Translation: AAC79118.1 |
CCDSi | CCDS8305.1 [Q13614-1] CCDS8306.1 [Q13614-2] |
PIRi | T09497 |
RefSeqi | NP_001230500.1, NM_001243571.1 [Q13614-2] NP_057240.3, NM_016156.5 [Q13614-1] NP_958435.1, NM_201278.2 [Q13614-2] NP_958438.1, NM_201281.2 [Q13614-2] XP_005274431.1, XM_005274374.2 [Q13614-2] XP_005274432.1, XM_005274375.2 [Q13614-2] XP_006718997.1, XM_006718934.2 XP_006718998.1, XM_006718935.2 XP_006718999.1, XM_006718936.3 XP_016874006.1, XM_017018517.1 XP_016874007.1, XM_017018518.1 |
Genome annotation databases
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Web resourcesi
Inherited peripheral neuropathies mutation db |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB028996 mRNA Translation: BAA83025.2 Different initiation. AK302940 mRNA Translation: BAG64098.1 AP000870 Genomic DNA No translation available. AP001877 Genomic DNA No translation available. CH471065 Genomic DNA Translation: EAW66971.1 BC052990 mRNA Translation: AAH52990.1 U58033 mRNA Translation: AAC79118.1 |
CCDSi | CCDS8305.1 [Q13614-1] CCDS8306.1 [Q13614-2] |
PIRi | T09497 |
RefSeqi | NP_001230500.1, NM_001243571.1 [Q13614-2] NP_057240.3, NM_016156.5 [Q13614-1] NP_958435.1, NM_201278.2 [Q13614-2] NP_958438.1, NM_201281.2 [Q13614-2] XP_005274431.1, XM_005274374.2 [Q13614-2] XP_005274432.1, XM_005274375.2 [Q13614-2] XP_006718997.1, XM_006718934.2 XP_006718998.1, XM_006718935.2 XP_006718999.1, XM_006718936.3 XP_016874006.1, XM_017018517.1 XP_016874007.1, XM_017018518.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1LW3 | X-ray | 2.30 | A | 1-643 | [»] | |
1M7R | X-ray | 2.60 | A/B | 1-643 | [»] | |
1ZSQ | X-ray | 1.82 | A | 73-586 | [»] | |
1ZVR | X-ray | 1.98 | A | 73-586 | [»] | |
5GNH | X-ray | 2.60 | A/B | 73-643 | [»] | |
SMRi | Q13614 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 114415, 55 interactors |
IntActi | Q13614, 12 interactors |
MINTi | Q13614 |
STRINGi | 9606.ENSP00000345752 |
Chemistry databases
SwissLipidsi | SLP:000001135 |
PTM databases
DEPODi | MTMR2 |
GlyGeni | Q13614, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q13614 |
MetOSitei | Q13614 |
PhosphoSitePlusi | Q13614 |
SwissPalmi | Q13614 |
Genetic variation databases
BioMutai | MTMR2 |
DMDMi | 212276520 |
Proteomic databases
EPDi | Q13614 |
jPOSTi | Q13614 |
MassIVEi | Q13614 |
MaxQBi | Q13614 |
PaxDbi | Q13614 |
PeptideAtlasi | Q13614 |
PRIDEi | Q13614 |
ProteomicsDBi | 1592 59600 [Q13614-1] |
Protocols and materials databases
Antibodypediai | 31676, 254 antibodies from 29 providers |
DNASUi | 8898 |
Genome annotation databases
Organism-specific databases
CTDi | 8898 |
DisGeNETi | 8898 |
GeneCardsi | MTMR2 |
GeneReviewsi | MTMR2 |
HGNCi | HGNC:7450, MTMR2 |
HPAi | ENSG00000087053, Low tissue specificity |
MalaCardsi | MTMR2 |
MIMi | 601382, phenotype 603557, gene |
neXtProti | NX_Q13614 |
OpenTargetsi | ENSG00000087053 |
Orphaneti | 99955, Charcot-Marie-Tooth disease type 4B1 |
PharmGKBi | PA31253 |
VEuPathDBi | HostDB:ENSG00000087053 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG4471, Eukaryota |
GeneTreei | ENSGT00940000153669 |
InParanoidi | Q13614 |
OMAi | ESYAICD |
OrthoDBi | 824298at2759 |
PhylomeDBi | Q13614 |
TreeFami | TF315197 |
Enzyme and pathway databases
BRENDAi | 3.1.3.64, 2681 3.1.3.95, 2681 |
PathwayCommonsi | Q13614 |
Reactomei | R-HSA-1483248, Synthesis of PIPs at the ER membrane R-HSA-1660499, Synthesis of PIPs at the plasma membrane R-HSA-1660516, Synthesis of PIPs at the early endosome membrane R-HSA-1660517, Synthesis of PIPs at the late endosome membrane |
SignaLinki | Q13614 |
Miscellaneous databases
BioGRID-ORCSi | 8898, 11 hits in 1052 CRISPR screens |
ChiTaRSi | MTMR2, human |
EvolutionaryTracei | Q13614 |
GeneWikii | MTMR2 |
GenomeRNAii | 8898 |
Pharosi | Q13614, Tbio |
PROi | PR:Q13614 |
RNActi | Q13614, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000087053, Expressed in testis and 237 other tissues |
ExpressionAtlasi | Q13614, baseline and differential |
Genevisiblei | Q13614, HS |
Family and domain databases
Gene3Di | 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR004182, GRAM IPR010569, Myotubularin-like_Pase_dom IPR030564, Myotubularin_fam IPR011993, PH-like_dom_sf IPR029021, Prot-tyrosine_phosphatase-like IPR016130, Tyr_Pase_AS IPR003595, Tyr_Pase_cat IPR000387, Tyr_Pase_dom |
PANTHERi | PTHR10807, PTHR10807, 1 hit |
Pfami | View protein in Pfam PF02893, GRAM, 1 hit PF06602, Myotub-related, 1 hit |
SMARTi | View protein in SMART SM00568, GRAM, 1 hit SM00404, PTPc_motif, 1 hit |
SUPFAMi | SSF52799, SSF52799, 1 hit |
PROSITEi | View protein in PROSITE PS51339, PPASE_MYOTUBULARIN, 1 hit PS00383, TYR_PHOSPHATASE_1, 1 hit PS50056, TYR_PHOSPHATASE_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MTMR2_HUMAN | |
Accessioni | Q13614Primary (citable) accession number: Q13614 Secondary accession number(s): A6NN98, Q9UPS9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 4, 2008 | |
Last modified: | February 23, 2022 | |
This is version 210 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families