UniProtKB - Q13536 (CROC4_HUMAN)
Protein
Protein CROC-4
Gene
MIR9-1HG
Organism
Homo sapiens (Human)
Status
Functioni
May play a role in FOS signaling pathways involved in development and remodeling of neurons. Promotes transcription of the FOS promoter.1 Publication
GO - Biological processi
- positive regulation of transcription by RNA polymerase II Source: UniProtKB
Enzyme and pathway databases
PathwayCommonsi | Q13536 |
SIGNORi | Q13536 |
Names & Taxonomyi
Protein namesi | Recommended name: Protein CROC-4Alternative name(s): Contingent replication of cDNA 4 MIR9-1 host geneImported |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000125462.16 |
HGNCi | HGNC:30780, MIR9-1HG |
MIMi | 618747, gene |
neXtProti | NX_Q13536 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPathology & Biotechi
Organism-specific databases
DisGeNETi | 10485 |
OpenTargetsi | ENSG00000125462 |
PharmGKBi | PA142672511 |
Miscellaneous databases
Pharosi | Q13536, Tdark |
Polymorphism and mutation databases
BioMutai | C1orf61 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000333952 | 1 – 156 | Protein CROC-4Add BLAST | 156 |
Proteomic databases
PaxDbi | Q13536 |
PRIDEi | Q13536 |
ProteomicsDBi | 59524 |
Expressioni
Tissue specificityi
Expressed throughout the brain in the thalamus, subthalamic nucleus, corpus callosum, hippocampus, substantia nigra, caudate nucleus, and amygdala.1 Publication
Gene expression databases
Bgeei | ENSG00000125462, Expressed in ventricular zone and 157 other tissues |
Genevisiblei | Q13536, HS |
Organism-specific databases
HPAi | ENSG00000125462, Tissue enriched (brain) |
Interactioni
Protein-protein interaction databases
BioGRIDi | 115748, 1 interactor |
Miscellaneous databases
RNActi | Q13536, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502TF2T, Eukaryota |
GeneTreei | ENSGT00390000005493 |
HOGENOMi | CLU_131272_0_0_1 |
InParanoidi | Q13536 |
OrthoDBi | 1271587at2759 |
PhylomeDBi | Q13536 |
TreeFami | TF342418 |
i Sequence
Sequence statusi: Complete.
Q13536-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFLTEDLITF NLRNFLLFQL WESSFSPGAG GFCTTLPPSF LRVDDRATSS
60 70 80 90 100
TTDSSRAPSS PRPPGSTSHC GISTRCTERC LCVLPLRTSQ VPDVMAPQHD
110 120 130 140 150
QEKFHDLAYS CLGKSFSMSN QDLYGYSTSS LALGLAWLSW ETKKKNVLHL
VGLDSL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U49857 mRNA Translation: AAA93029.1 AL139130 Genomic DNA No translation available. CH471121 Genomic DNA Translation: EAW52956.1 |
RefSeqi | NP_006356.1, NM_006365.2 XP_011507372.1, XM_011509070.1 XP_011507373.1, XM_011509071.2 XP_011507374.1, XM_011509072.1 XP_016855551.1, XM_017000062.1 XP_016855552.1, XM_017000063.1 |
Genome annotation databases
Ensembli | ENST00000615748; ENSP00000479346; ENSG00000125462 |
GeneIDi | 10485 |
UCSCi | uc001fou.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U49857 mRNA Translation: AAA93029.1 AL139130 Genomic DNA No translation available. CH471121 Genomic DNA Translation: EAW52956.1 |
RefSeqi | NP_006356.1, NM_006365.2 XP_011507372.1, XM_011509070.1 XP_011507373.1, XM_011509071.2 XP_011507374.1, XM_011509072.1 XP_016855551.1, XM_017000062.1 XP_016855552.1, XM_017000063.1 |
3D structure databases
SMRi | Q13536 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 115748, 1 interactor |
Polymorphism and mutation databases
BioMutai | C1orf61 |
Proteomic databases
PaxDbi | Q13536 |
PRIDEi | Q13536 |
ProteomicsDBi | 59524 |
Protocols and materials databases
Antibodypediai | 34216, 12 antibodies |
DNASUi | 10485 |
Genome annotation databases
Ensembli | ENST00000615748; ENSP00000479346; ENSG00000125462 |
GeneIDi | 10485 |
UCSCi | uc001fou.2, human |
Organism-specific databases
CTDi | 10485 |
DisGeNETi | 10485 |
EuPathDBi | HostDB:ENSG00000125462.16 |
GeneCardsi | MIR9-1HG |
HGNCi | HGNC:30780, MIR9-1HG |
HPAi | ENSG00000125462, Tissue enriched (brain) |
MIMi | 618747, gene |
neXtProti | NX_Q13536 |
OpenTargetsi | ENSG00000125462 |
PharmGKBi | PA142672511 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502TF2T, Eukaryota |
GeneTreei | ENSGT00390000005493 |
HOGENOMi | CLU_131272_0_0_1 |
InParanoidi | Q13536 |
OrthoDBi | 1271587at2759 |
PhylomeDBi | Q13536 |
TreeFami | TF342418 |
Enzyme and pathway databases
PathwayCommonsi | Q13536 |
SIGNORi | Q13536 |
Miscellaneous databases
BioGRID-ORCSi | 10485, 1 hit in 844 CRISPR screens |
ChiTaRSi | C1orf61, human |
GenomeRNAii | 10485 |
Pharosi | Q13536, Tdark |
PROi | PR:Q13536 |
RNActi | Q13536, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000125462, Expressed in ventricular zone and 157 other tissues |
Genevisiblei | Q13536, HS |
Family and domain databases
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CROC4_HUMAN | |
Accessioni | Q13536Primary (citable) accession number: Q13536 Secondary accession number(s): B1ALL5, B1ALL8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 20, 2008 |
Last sequence update: | November 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM