UniProtKB - Q13362 (2A5G_HUMAN)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
PPP2R5C
Functioni
GO - Molecular functioni
- protein phosphatase activator activity Source: GO_Central
- protein phosphatase regulator activity Source: UniProtKB
GO - Biological processi
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Source: UniProtKB
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Source: UniProtKB
- negative regulation of cell population proliferation Source: UniProtKB
- negative regulation of protein kinase B signaling Source: Reactome
- proteasome-mediated ubiquitin-dependent protein catabolic process Source: MGI
- protein dephosphorylation Source: GO_Central
- regulation of phosphatidylinositol 3-kinase signaling Source: Reactome
- regulation of protein autophosphorylation Source: GO_Central
- signal transduction Source: UniProtKB
Enzyme and pathway databases
PathwayCommonsi | Q13362 |
Reactomei | R-HSA-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-195253, Degradation of beta-catenin by the destruction complex R-HSA-196299, Beta-catenin phosphorylation cascade R-HSA-2467813, Separation of Sister Chromatids R-HSA-2500257, Resolution of Sister Chromatid Cohesion R-HSA-389513, CTLA4 inhibitory signaling R-HSA-432142, Platelet sensitization by LDL R-HSA-4641262, Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-5339716, Misspliced GSK3beta mutants stabilize beta-catenin R-HSA-5358747, S33 mutants of beta-catenin aren't phosphorylated R-HSA-5358749, S37 mutants of beta-catenin aren't phosphorylated R-HSA-5358751, S45 mutants of beta-catenin aren't phosphorylated R-HSA-5358752, T41 mutants of beta-catenin aren't phosphorylated R-HSA-5467337, APC truncation mutants have impaired AXIN binding R-HSA-5467340, AXIN missense mutants destabilize the destruction complex R-HSA-5467348, Truncations of AMER1 destabilize the destruction complex R-HSA-5663220, RHO GTPases Activate Formins R-HSA-5673000, RAF activation R-HSA-5675221, Negative regulation of MAPK pathway R-HSA-6804757, Regulation of TP53 Degradation R-HSA-6811558, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-68877, Mitotic Prometaphase R-HSA-9648025, EML4 and NUDC in mitotic spindle formation |
SignaLinki | Q13362 |
SIGNORi | Q13362 |
Names & Taxonomyi
Protein namesi | Recommended name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoformAlternative name(s): PP2A B subunit isoform B'-gamma PP2A B subunit isoform B56-gamma PP2A B subunit isoform PR61-gamma PP2A B subunit isoform R5-gamma Renal carcinoma antigen NY-REN-29 |
Gene namesi | Name:PPP2R5C Synonyms:KIAA0044 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000078304.19 |
HGNCi | HGNC:9311, PPP2R5C |
MIMi | 601645, gene |
neXtProti | NX_Q13362 |
Subcellular locationi
Nucleus
Other locations
Cytosol
- cytosol Source: HPA
Golgi apparatus
- Golgi apparatus Source: HPA
Nucleus
- nucleoplasm Source: HPA
- nucleus Source: UniProtKB
Other locations
- chromosome, centromeric region Source: UniProtKB
- protein phosphatase type 2A complex Source: UniProtKB
Keywords - Cellular componenti
Centromere, Chromosome, NucleusPathology & Biotechi
Organism-specific databases
DisGeNETi | 5527 |
OpenTargetsi | ENSG00000078304 |
PharmGKBi | PA33674 |
Miscellaneous databases
Pharosi | Q13362, Tbio |
Chemistry databases
DrugBanki | DB06905, (2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid DB02506, 2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid |
Polymorphism and mutation databases
BioMutai | PPP2R5C |
DMDMi | 116241235 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000071457 | 1 – 524 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoformAdd BLAST | 524 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineCombined sources | 1 |
Post-translational modificationi
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
jPOSTi | Q13362 |
MassIVEi | Q13362 |
MaxQBi | Q13362 |
PaxDbi | Q13362 |
PeptideAtlasi | Q13362 |
PRIDEi | Q13362 |
ProteomicsDBi | 24176 59345 59346 [Q13362-2] 59347 [Q13362-3] 59348 [Q13362-4] |
PTM databases
iPTMneti | Q13362 |
PhosphoSitePlusi | Q13362 |
SwissPalmi | Q13362 |
Expressioni
Tissue specificityi
Inductioni
Gene expression databases
Bgeei | ENSG00000078304, Expressed in sperm and 244 other tissues |
ExpressionAtlasi | Q13362, baseline and differential |
Genevisiblei | Q13362, HS |
Organism-specific databases
HPAi | ENSG00000078304, Low tissue specificity |
Interactioni
Subunit structurei
PP2A consists of a common heterodimeric core enzyme, composed of PPP2CA a 36 kDa catalytic subunit (subunit C) and PPP2R1A a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.
Interacts with PPP2CA AND PPP2R1A; the interaction is direct.
Interacts with SGO1; the interaction is direct. Isoform 1 and isoform 2 interact with TP53 (phosphorylated at Ser-15 by ATM); increased upon DNA damage it drives PP2A-mediated dephosphorylation of TP53 at Thr-55.
Interacts with IER3 and/or ERK kinases; regulates ERK dephosphorylation.
Interacts with CIP2A; this interaction stabilizes CIP2A (PubMed:28174209).
9 PublicationsBinary interactionsi
Hide detailsQ13362
Isoform Gamma-3 [Q13362-1]
With | #Exp. | IntAct |
---|---|---|
CHEK2 [O96017] | 3 | EBI-1266170,EBI-1180783 |
PPP2R1A [P30153] | 5 | EBI-1266170,EBI-302388 |
Isoform Gamma-1 [Q13362-2]
With | #Exp. | IntAct |
---|---|---|
CHEK2 [O96017] | 2 | EBI-1266173,EBI-1180783 |
PPP2R1A [P30153] | 4 | EBI-1266173,EBI-302388 |
Isoform Gamma-2 [Q13362-3]
With | #Exp. | IntAct |
---|---|---|
CHEK2 [O96017] | 4 | EBI-1266176,EBI-1180783 |
Protein-protein interaction databases
BioGRIDi | 111519, 45 interactors |
DIPi | DIP-39401N |
ELMi | Q13362 |
IntActi | Q13362, 29 interactors |
MINTi | Q13362 |
STRINGi | 9606.ENSP00000412324 |
Miscellaneous databases
RNActi | Q13362, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q13362 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q13362 |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 416 – 422 | Nuclear localization signalSequence analysis | 7 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG2085, Eukaryota |
GeneTreei | ENSGT01010000222363 |
HOGENOMi | CLU_012437_3_2_1 |
InParanoidi | Q13362 |
OMAi | ECSQNFN |
OrthoDBi | 890437at2759 |
PhylomeDBi | Q13362 |
TreeFami | TF105556 |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR002554, PP2A_B56 |
PANTHERi | PTHR10257, PTHR10257, 1 hit |
Pfami | View protein in Pfam PF01603, B56, 1 hit |
PIRSFi | PIRSF028043, PP2A_B56, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
s (5+)i Sequence
Sequence statusi: Complete.
This entry describes 5 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 5 described isoforms and 16 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MLTCNKAGSR MVVDAANSNG PFQPVVLLHI RDVPPADQEK LFIQKLRQCC
60 70 80 90 100
VLFDFVSDPL SDLKWKEVKR AALSEMVEYI THNRNVITEP IYPEVVHMFA
110 120 130 140 150
VNMFRTLPPS SNPTGAEFDP EEDEPTLEAA WPHLQLVYEF FLRFLESPDF
160 170 180 190 200
QPNIAKKYID QKFVLQLLEL FDSEDPRERD FLKTTLHRIY GKFLGLRAYI
210 220 230 240 250
RKQINNIFYR FIYETEHHNG IAELLEILGS IINGFALPLK EEHKIFLLKV
260 270 280 290 300
LLPLHKVKSL SVYHPQLAYC VVQFLEKDST LTEPVVMALL KYWPKTHSPK
310 320 330 340 350
EVMFLNELEE ILDVIEPSEF VKIMEPLFRQ LAKCVSSPHF QVAERALYYW
360 370 380 390 400
NNEYIMSLIS DNAAKILPIM FPSLYRNSKT HWNKTIHGLI YNALKLFMEM
410 420 430 440 450
NQKLFDDCTQ QFKAEKLKEK LKMKEREEAW VKIENLAKAN PQYTVYSQAS
460 470 480 490 500
TMSIPVAMET DGPLFEDVQM LRKTVKDEAH QAQKDPKKDR PLARRKSELP
510 520
QDPHTKKALE AHCRADELAS QDGR
The sequence of this isoform differs from the canonical sequence as follows:
443-524: YTVYSQASTM...ADELASQDGR → VLKKRIT
The sequence of this isoform differs from the canonical sequence as follows:
443-481: Missing.
Computationally mapped potential isoform sequencesi
There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ96B13 | Q96B13_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 384 | Annotation score: | ||
H0YJ75 | H0YJ75_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 553 | Annotation score: | ||
H0YJ35 | H0YJ35_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 71 | Annotation score: | ||
G3V292 | G3V292_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 124 | Annotation score: | ||
G3V2U3 | G3V2U3_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 216 | Annotation score: | ||
H0YJ49 | H0YJ49_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 151 | Annotation score: | ||
H0YJU0 | H0YJU0_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 153 | Annotation score: | ||
H0YN84 | H0YN84_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 89 | Annotation score: | ||
H0YJZ3 | H0YJZ3_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 69 | Annotation score: | ||
H0YK26 | H0YK26_HUMAN | Serine/threonine-protein phosphatas... | PPP2R5C | 146 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
Sequence conflicti | 494 | R → L in AAC50387 (PubMed:8617797).Curated | 1 | ||
Isoform 5 (identifier: Q13362-5) | |||||
Sequence conflicti | 3 | N → K in BAG63760 (PubMed:14702039).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_051745 | 515 | A → P. Corresponds to variant dbSNP:rs3742424Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_043645 | 1 – 31 | MLTCN…LLHIR → MPNKNKKEKESPKAGKSGKS SKEGQDTVESEQISVRKNSL VAVPSTVSAKIKVPVSQPIV KKDKRQNSSRFSASNNRELQ KLPSLK in isoform 4. 1 PublicationAdd BLAST | 31 | |
Alternative sequenceiVSP_046768 | 1 – 30 | MLTCN…VLLHI → MPNKNKKEKESPKAGKSGKS SKEGQDTVESEGTSPEEPSS PKVPPPLLPELLVLIFGGLQ G in isoform 5. CuratedAdd BLAST | 30 | |
Alternative sequenceiVSP_005112 | 443 – 524 | YTVYS…SQDGR → VLKKRIT in isoform Gamma-1. 2 PublicationsAdd BLAST | 82 | |
Alternative sequenceiVSP_005113 | 443 – 481 | Missing in isoform Gamma-2 and isoform 4. 2 PublicationsAdd BLAST | 39 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U37352 mRNA Translation: AAC50387.1 Different initiation. Z69030 mRNA Translation: CAA93154.1 AK131391 mRNA Translation: BAD18542.1 AK302470 mRNA Translation: BAG63760.1 Different initiation. AB451341 mRNA Translation: BAG70155.1 AL118558 Genomic DNA No translation available. AL137779 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW81756.1 D26445 mRNA Translation: BAA05465.1 L42375 mRNA Translation: AAC37603.1 |
CCDSi | CCDS45163.1 [Q13362-2] CCDS53911.1 [Q13362-4] CCDS53912.1 [Q13362-5] CCDS9964.1 [Q13362-1] CCDS9965.1 [Q13362-3] |
RefSeqi | NP_001155197.1, NM_001161725.1 [Q13362-5] NP_001155198.1, NM_001161726.1 [Q13362-4] NP_002710.2, NM_002719.3 [Q13362-1] NP_848701.1, NM_178586.2 [Q13362-3] NP_848702.1, NM_178587.2 [Q13362-2] XP_005267884.1, XM_005267827.1 XP_011535222.1, XM_011536920.1 |
Genome annotation databases
Ensembli | ENST00000328724; ENSP00000329009; ENSG00000078304 [Q13362-4] ENST00000334743; ENSP00000333905; ENSG00000078304 [Q13362-1] ENST00000350249; ENSP00000262239; ENSG00000078304 [Q13362-3] ENST00000422945; ENSP00000412324; ENSG00000078304 [Q13362-5] ENST00000445439; ENSP00000408389; ENSG00000078304 [Q13362-2] |
GeneIDi | 5527 |
KEGGi | hsa:5527 |
UCSCi | uc001ykk.4, human [Q13362-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U37352 mRNA Translation: AAC50387.1 Different initiation. Z69030 mRNA Translation: CAA93154.1 AK131391 mRNA Translation: BAD18542.1 AK302470 mRNA Translation: BAG63760.1 Different initiation. AB451341 mRNA Translation: BAG70155.1 AL118558 Genomic DNA No translation available. AL137779 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW81756.1 D26445 mRNA Translation: BAA05465.1 L42375 mRNA Translation: AAC37603.1 |
CCDSi | CCDS45163.1 [Q13362-2] CCDS53911.1 [Q13362-4] CCDS53912.1 [Q13362-5] CCDS9964.1 [Q13362-1] CCDS9965.1 [Q13362-3] |
RefSeqi | NP_001155197.1, NM_001161725.1 [Q13362-5] NP_001155198.1, NM_001161726.1 [Q13362-4] NP_002710.2, NM_002719.3 [Q13362-1] NP_848701.1, NM_178586.2 [Q13362-3] NP_848702.1, NM_178587.2 [Q13362-2] XP_005267884.1, XM_005267827.1 XP_011535222.1, XM_011536920.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2IAE | X-ray | 3.50 | B/E | 30-436 | [»] | |
2JAK | X-ray | 2.60 | A | 11-380 | [»] | |
2NPP | X-ray | 3.30 | B/E | 1-442 | [»] | |
2NYL | X-ray | 3.80 | B/E | 38-425 | [»] | |
2NYM | X-ray | 3.60 | B/E | 38-425 | [»] | |
3FGA | X-ray | 2.70 | B | 34-436 | [»] | |
5JJA | X-ray | 2.35 | A/B | 30-380 | [»] | |
5K6S | X-ray | 2.79 | A | 31-380 | [»] | |
5SW9 | X-ray | 2.85 | A | 31-380 | [»] | |
5SWF | X-ray | 2.82 | A | 31-380 | [»] | |
6OYL | X-ray | 3.15 | A | 31-380 | [»] | |
6VOY | electron microscopy | 3.70 | E/F | 30-372 | [»] | |
6VRO | X-ray | 2.45 | A | 31-380 | [»] | |
SMRi | Q13362 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 111519, 45 interactors |
DIPi | DIP-39401N |
ELMi | Q13362 |
IntActi | Q13362, 29 interactors |
MINTi | Q13362 |
STRINGi | 9606.ENSP00000412324 |
Chemistry databases
DrugBanki | DB06905, (2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid DB02506, 2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid |
PTM databases
iPTMneti | Q13362 |
PhosphoSitePlusi | Q13362 |
SwissPalmi | Q13362 |
Polymorphism and mutation databases
BioMutai | PPP2R5C |
DMDMi | 116241235 |
Proteomic databases
jPOSTi | Q13362 |
MassIVEi | Q13362 |
MaxQBi | Q13362 |
PaxDbi | Q13362 |
PeptideAtlasi | Q13362 |
PRIDEi | Q13362 |
ProteomicsDBi | 24176 59345 59346 [Q13362-2] 59347 [Q13362-3] 59348 [Q13362-4] |
Protocols and materials databases
Antibodypediai | 27667, 234 antibodies |
DNASUi | 5527 |
Genome annotation databases
Ensembli | ENST00000328724; ENSP00000329009; ENSG00000078304 [Q13362-4] ENST00000334743; ENSP00000333905; ENSG00000078304 [Q13362-1] ENST00000350249; ENSP00000262239; ENSG00000078304 [Q13362-3] ENST00000422945; ENSP00000412324; ENSG00000078304 [Q13362-5] ENST00000445439; ENSP00000408389; ENSG00000078304 [Q13362-2] |
GeneIDi | 5527 |
KEGGi | hsa:5527 |
UCSCi | uc001ykk.4, human [Q13362-1] |
Organism-specific databases
CTDi | 5527 |
DisGeNETi | 5527 |
EuPathDBi | HostDB:ENSG00000078304.19 |
GeneCardsi | PPP2R5C |
HGNCi | HGNC:9311, PPP2R5C |
HPAi | ENSG00000078304, Low tissue specificity |
MIMi | 601645, gene |
neXtProti | NX_Q13362 |
OpenTargetsi | ENSG00000078304 |
PharmGKBi | PA33674 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG2085, Eukaryota |
GeneTreei | ENSGT01010000222363 |
HOGENOMi | CLU_012437_3_2_1 |
InParanoidi | Q13362 |
OMAi | ECSQNFN |
OrthoDBi | 890437at2759 |
PhylomeDBi | Q13362 |
TreeFami | TF105556 |
Enzyme and pathway databases
PathwayCommonsi | Q13362 |
Reactomei | R-HSA-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-195253, Degradation of beta-catenin by the destruction complex R-HSA-196299, Beta-catenin phosphorylation cascade R-HSA-2467813, Separation of Sister Chromatids R-HSA-2500257, Resolution of Sister Chromatid Cohesion R-HSA-389513, CTLA4 inhibitory signaling R-HSA-432142, Platelet sensitization by LDL R-HSA-4641262, Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-5339716, Misspliced GSK3beta mutants stabilize beta-catenin R-HSA-5358747, S33 mutants of beta-catenin aren't phosphorylated R-HSA-5358749, S37 mutants of beta-catenin aren't phosphorylated R-HSA-5358751, S45 mutants of beta-catenin aren't phosphorylated R-HSA-5358752, T41 mutants of beta-catenin aren't phosphorylated R-HSA-5467337, APC truncation mutants have impaired AXIN binding R-HSA-5467340, AXIN missense mutants destabilize the destruction complex R-HSA-5467348, Truncations of AMER1 destabilize the destruction complex R-HSA-5663220, RHO GTPases Activate Formins R-HSA-5673000, RAF activation R-HSA-5675221, Negative regulation of MAPK pathway R-HSA-6804757, Regulation of TP53 Degradation R-HSA-6811558, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-68877, Mitotic Prometaphase R-HSA-9648025, EML4 and NUDC in mitotic spindle formation |
SignaLinki | Q13362 |
SIGNORi | Q13362 |
Miscellaneous databases
BioGRID-ORCSi | 5527, 19 hits in 846 CRISPR screens |
ChiTaRSi | PPP2R5C, human |
EvolutionaryTracei | Q13362 |
GeneWikii | PPP2R5C |
GenomeRNAii | 5527 |
Pharosi | Q13362, Tbio |
PROi | PR:Q13362 |
RNActi | Q13362, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000078304, Expressed in sperm and 244 other tissues |
ExpressionAtlasi | Q13362, baseline and differential |
Genevisiblei | Q13362, HS |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR002554, PP2A_B56 |
PANTHERi | PTHR10257, PTHR10257, 1 hit |
Pfami | View protein in Pfam PF01603, B56, 1 hit |
PIRSFi | PIRSF028043, PP2A_B56, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | 2A5G_HUMAN | |
Accessioni | Q13362Primary (citable) accession number: Q13362 Secondary accession number(s): B4DYJ8 Q6ZN33 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | October 17, 2006 | |
Last modified: | December 2, 2020 | |
This is version 200 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations