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UniProtKB - Q13316 (DMP1_HUMAN)

Entry version 155 (11 Dec 2019)
Sequence version 2 (01 Jan 1998)
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Protein

Dentin matrix acidic phosphoprotein 1

Gene

DMP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • calcium ion binding Source: ProtInc
  • extracellular matrix binding Source: Ensembl
  • integrin binding Source: ProtInc
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processBiomineralization

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-3000178 ECM proteoglycans
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-8957275 Post-translational protein phosphorylation

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q13316

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dentin matrix acidic phosphoprotein 1
Short name:
DMP-1
Short name:
Dentin matrix protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DMP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000152592.13

Human Gene Nomenclature Database

More...HGNCi		HGNC:2932 DMP1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		600980 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q13316

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Extracellular matrix, Nucleus, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Hypophosphatemic rickets, autosomal recessive, 1 (ARHR1)2 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA hereditary form of hypophosphatemic rickets, a disorder of proximal renal tubule function that causes phosphate loss, hypophosphatemia and skeletal deformities, including rickets and osteomalacia unresponsive to vitamin D. Symptoms are bone pain, fractures and growth abnormalities.
Related information in OMIM

Organism-specific databases

DisGeNET

More...DisGeNETi		1758

MalaCards human disease database

More...MalaCardsi		DMP1
MIMi241520 phenotype

Open Targets

More...OpenTargetsi		ENSG00000152592

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...Orphaneti		289176 Autosomal recessive hypophosphatemic rickets

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA27379

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q13316 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		DMP1

Domain mapping of disease mutations (DMDM)

More...DMDMi		7673998

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 16Sequence analysisAdd BLAST16
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002111017 – 513Dentin matrix acidic phosphoprotein 1Add BLAST497

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi25N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi285N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi324N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi345N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi351N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi413N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi426N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi467N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated in the cytosol and extracellular matrix and unphosphorylated in the nucleus. Phosphorylation is necessary for nucleocytoplasmic transport and may be catalyzed by a nuclear isoform of CK2 and can be augmented by calcium. Phosphorylated (in vitro) by FAM20C in the extracellular medium at sites within the S-x-E/pS motif.2 Publications

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q13316

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q13316

PeptideAtlas

More...PeptideAtlasi		Q13316

PRoteomics IDEntifications database

More...PRIDEi		Q13316

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		59304 [Q13316-1]
59305 [Q13316-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q13316

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q13316

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in tooth particularly in odontoblast, ameloblast and cementoblast.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000152592 Expressed in 80 organ(s), highest expression level in tibia

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q13316 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA037465

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with importin alpha.

1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		108098, 1 interactor

Protein interaction database and analysis system

More...IntActi		Q13316, 1 interactor

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000340935

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q13316 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi364 – 366Cell attachment siteSequence analysis3

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1181 Eukaryota
ENOG4111M3T LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00730000111375

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000220909

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q13316

KEGG Orthology (KO)

More...KOi		K23328

Identification of Orthologs from Complete Genome Data

More...OMAi		ARYQNTE

Database of Orthologous Groups

More...OrthoDBi		1235561at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q13316

TreeFam database of animal gene trees

More...TreeFami		TF337029

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR009889 DMP1

The PANTHER Classification System

More...PANTHERi		PTHR23400 PTHR23400, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07263 DMP1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q13316-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKISILLMFL WGLSCALPVT RYQNNESEDS EEWKGHLAQA PTPPLESSES 
        60         70         80         90        100
SEGSKVSSEE QANEDPSDST QSEEGLGSDD HQYIYRLAGG FSRSTGKGGD 
       110        120        130        140        150
DKDDDEDDSG DDTFGDDDSG PGPKDRQEGG NSRLGSDEDS DDTIQASEES 
       160        170        180        190        200
APQGQDSAQD TTSESRELDN EDRVDSKPEG GDSTQESESE EHWVGGGSDG 
       210        220        230        240        250
ESSHGDGSEL DDEGMQSDDP ESIRSERGNS RMNSAGMKSK ESGENSEQAN 
       260        270        280        290        300
TQDSGGSQLL EHPSRKIFRK SRISEEDDRS ELDDNNTMEE VKSDSTENSN 
       310        320        330        340        350
SRDTGLSQPR RDSKGDSQED SKENLSQEES QNVDGPSSES SQEANLSSQE 
       360        370        380        390        400
NSSESQEEVV SESRGDNPDP TTSYVEDQED SDSSEEDSSH TLSHSKSESR 
       410        420        430        440        450
EEQADSESSE SLNFSEESPE SPEDENSSSQ EGLQSHSSSA ESQSEESHSE 
       460        470        480        490        500
EDDSDSQDSS RSKEDSNSTE SKSSSEEDGQ LKNIEIESRK LTVDAYHNKP 
       510 
IGDQDDNDCQ DGY
Length:513
Mass (Da):55,782
Last modified:January 1, 1998 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2C1FDE319A5D106F
GO
Isoform 2 (identifier: Q13316-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     46-61: Missing.

Show »
Length:497
Mass (Da):54,115
Checksum:i6E146232B6365507
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03075069S → C2 PublicationsCorresponds to variant dbSNP:rs10019009EnsemblClinVar.1
Natural variantiVAR_030751117D → N in one individual with tumoral calcinosis. 1 PublicationCorresponds to variant dbSNP:rs140719182Ensembl.1
Natural variantiVAR_030752272R → H1 PublicationCorresponds to variant dbSNP:rs145237146EnsemblClinVar.1
Natural variantiVAR_033848463K → R. Corresponds to variant dbSNP:rs34661425EnsemblClinVar.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_00419146 – 61Missing in isoform 2. 1 PublicationAdd BLAST16

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U89012 mRNA Translation: AAC51332.1
U34037 Genomic DNA Translation: AAA97602.1
CH471057 Genomic DNA Translation: EAX05996.1
BC130581 mRNA Translation: AAI30582.1
BC132865 mRNA Translation: AAI32866.1
U65378 mRNA Translation: AAB87728.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS3623.1 [Q13316-1]
CCDS43249.1 [Q13316-2]

NCBI Reference Sequences

More...RefSeqi		NP_001073380.1, NM_001079911.2 [Q13316-2]
NP_004398.1, NM_004407.3 [Q13316-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000282479; ENSP00000282479; ENSG00000152592 [Q13316-2]
ENST00000339673; ENSP00000340935; ENSG00000152592 [Q13316-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		1758

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:1758

UCSC genome browser

More...UCSCi		uc003hqv.4 human [Q13316-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89012 mRNA Translation: AAC51332.1
U34037 Genomic DNA Translation: AAA97602.1
CH471057 Genomic DNA Translation: EAX05996.1
BC130581 mRNA Translation: AAI30582.1
BC132865 mRNA Translation: AAI32866.1
U65378 mRNA Translation: AAB87728.1
CCDSiCCDS3623.1 [Q13316-1]
CCDS43249.1 [Q13316-2]
RefSeqiNP_001073380.1, NM_001079911.2 [Q13316-2]
NP_004398.1, NM_004407.3 [Q13316-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGridi108098, 1 interactor
IntActiQ13316, 1 interactor
STRINGi9606.ENSP00000340935

PTM databases

iPTMnetiQ13316
PhosphoSitePlusiQ13316

Polymorphism and mutation databases

BioMutaiDMP1
DMDMi7673998

Proteomic databases

MassIVEiQ13316
PaxDbiQ13316
PeptideAtlasiQ13316
PRIDEiQ13316
ProteomicsDBi59304 [Q13316-1]
59305 [Q13316-2]

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		1758

Genome annotation databases

EnsembliENST00000282479; ENSP00000282479; ENSG00000152592 [Q13316-2]
ENST00000339673; ENSP00000340935; ENSG00000152592 [Q13316-1]
GeneIDi1758
KEGGihsa:1758
UCSCiuc003hqv.4 human [Q13316-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		1758
DisGeNETi1758
EuPathDBiHostDB:ENSG00000152592.13

GeneCards: human genes, protein and diseases

More...GeneCardsi		DMP1
HGNCiHGNC:2932 DMP1
HPAiHPA037465
MalaCardsiDMP1
MIMi241520 phenotype
600980 gene
neXtProtiNX_Q13316
OpenTargetsiENSG00000152592
Orphaneti289176 Autosomal recessive hypophosphatemic rickets
PharmGKBiPA27379

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1181 Eukaryota
ENOG4111M3T LUCA
GeneTreeiENSGT00730000111375
HOGENOMiHOG000220909
InParanoidiQ13316
KOiK23328
OMAiARYQNTE
OrthoDBi1235561at2759
PhylomeDBiQ13316
TreeFamiTF337029

Enzyme and pathway databases

ReactomeiR-HSA-3000178 ECM proteoglycans
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-8957275 Post-translational protein phosphorylation
SignaLinkiQ13316

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		DMP1_(gene)

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		1758
PharosiQ13316 Tbio

Protein Ontology

More...PROi		PR:Q13316
RNActiQ13316 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000152592 Expressed in 80 organ(s), highest expression level in tibia
GenevisibleiQ13316 HS

Family and domain databases

InterProiView protein in InterPro
IPR009889 DMP1
PANTHERiPTHR23400 PTHR23400, 1 hit
PfamiView protein in Pfam
PF07263 DMP1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDMP1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q13316
Secondary accession number(s): A1L4L3, O43265
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: December 11, 2019
This is version 155 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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