UniProtKB - Q13304 (GPR17_HUMAN)

BLAST

>sp|Q13304|GPR17_HUMAN Uracil nucleotide/cysteinyl leukotriene receptor OS=Homo sapiens OX=9606 GN=GPR17 PE=2 SV=2
MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENM
LFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHF
SGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLAC
AFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCY
LLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQ
RILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESS
LSAKSEL

Align

Format
Add to basket Added to basket
History
Entry version 149 (07 Nov 2018)
Sequence version 2 (27 May 2002)
Previous versions | rss
Other tutorials and videos
Help video
Feedback

Protein

Uracil nucleotide/cysteinyl leukotriene receptor

Gene

GPR17

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at transcript levelⁱ

Functionⁱ

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.1 Publication

GO - Molecular functionⁱ

chemokine receptor activity
Source: ProtInc
Traceable author statementⁱ
- 8558062
G protein-coupled receptor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
receptor serine/threonine kinase binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

G protein-coupled receptor signaling pathway Source: Reactome
negative regulation of inflammatory response to antigenic stimulus Source: Ensembl
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
positive regulation of Rho protein signal transduction
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptor, Receptor, Transducer

Molecular function

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactomeⁱ	R-HSA-391906 Leukotriene receptors R-HSA-416476 G alpha (q) signalling events R-HSA-417957 P2Y receptors R-HSA-418594 G alpha (i) signalling events

Reactomeⁱ

R-HSA-391906 Leukotriene receptors
R-HSA-416476 G alpha (q) signalling events
R-HSA-417957 P2Y receptors
R-HSA-418594 G alpha (i) signalling events

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Uracil nucleotide/cysteinyl leukotriene receptor Short name: UDP/CysLT receptor Alternative name(s): G-protein coupled receptor 17 P2Y-like receptor R12
Gene namesⁱ	Name:GPR17
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 2

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000144230.16
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:4471 GPR17
MIMⁱ	603071 gene
neXtProtⁱ	NX_Q13304

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 64	ExtracellularSequence analysisAdd BLAST	64
Transmembraneⁱ	65 – 85	Helical; Name=1Sequence analysisAdd BLAST	21
Topological domainⁱ	86 – 92	CytoplasmicSequence analysis	7
Transmembraneⁱ	93 – 113	Helical; Name=2Sequence analysisAdd BLAST	21
Topological domainⁱ	114 – 133	ExtracellularSequence analysisAdd BLAST	20
Transmembraneⁱ	134 – 154	Helical; Name=3Sequence analysisAdd BLAST	21
Topological domainⁱ	155 – 175	CytoplasmicSequence analysisAdd BLAST	21
Transmembraneⁱ	176 – 196	Helical; Name=4Sequence analysisAdd BLAST	21
Topological domainⁱ	197 – 223	ExtracellularSequence analysisAdd BLAST	27
Transmembraneⁱ	224 – 244	Helical; Name=5Sequence analysisAdd BLAST	21
Topological domainⁱ	245 – 260	CytoplasmicSequence analysisAdd BLAST	16
Transmembraneⁱ	261 – 281	Helical; Name=6Sequence analysisAdd BLAST	21
Topological domainⁱ	282 – 308	ExtracellularSequence analysisAdd BLAST	27
Transmembraneⁱ	309 – 329	Helical; Name=7Sequence analysisAdd BLAST	21
Topological domainⁱ	330 – 367	CytoplasmicSequence analysisAdd BLAST	38

Keywords - Cellular componentⁱ

Cell membrane, Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	2840
Open Targets More...OpenTargetsⁱ	ENSG00000144230
PharmGKBⁱ	PA28859

Chemistry databases

ChEMBLⁱ	CHEMBL1075162
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	88

Polymorphism and mutation databases

BioMutaⁱ	GPR17
DMDMⁱ	21264435

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000069536	1 – 367	Uracil nucleotide/cysteinyl leukotriene receptorAdd BLAST		367

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	42	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	132 ↔ 209	PROSITE-ProRule annotation
Glycosylationⁱ	204	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	282	N-linked (GlcNAc...) asparagineSequence analysis	1

Keywords - PTMⁱ

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbⁱ	Q13304
PeptideAtlas More...PeptideAtlasⁱ	Q13304
PRIDEⁱ	Q13304
ProteomicsDBⁱ	59291 59292 [Q13304-2]

PTM databases

iPTMnetⁱ	Q13304
PhosphoSitePlusⁱ	Q13304

Expressionⁱ

Tissue specificityⁱ

Gene expression databases

Bgeeⁱ	ENSG00000144230 Expressed in 113 organ(s), highest expression level in heart left ventricle
CleanExⁱ	HS_GPR17
ExpressionAtlasⁱ	Q13304 baseline and differential
Genevisibleⁱ	Q13304 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA029766

HPAⁱ

HPA029766

Interactionⁱ

GO - Molecular functionⁱ

receptor serine/threonine kinase binding Source: Ensembl

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	109099, 1 interactor
STRINGⁱ	9606.ENSP00000272644

Chemistry databases

BindingDBⁱ

Q13304

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q13304
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG410IGZC Eukaryota ENOG41110RZ LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000148939
HOGENOMⁱ	HOG000236328
HOVERGENⁱ	HBG102010
InParanoidⁱ	Q13304
KEGG Orthology (KO) More...KOⁱ	K08404
OMAⁱ	FSGNHWP
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0A8K
PhylomeDBⁱ	Q13304
TreeFamⁱ	TF330775

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show all Align All

Isoform 1 (identifier: Q13304-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSKRSWWAGS RKPPREMLKL SGSDSSQSMN GLEVAPPGLI TNFSLATAEQ 
        60         70         80         90        100
CGQETPLENM LFASFYLLDF ILALVGNTLA LWLFIRDHKS GTPANVFLMH 
       110        120        130        140        150
LAVADLSCVL VLPTRLVYHF SGNHWPFGEI ACRLTGFLFY LNMYASIYFL 
       160        170        180        190        200
TCISADRFLA IVHPVKSLKL RRPLYAHLAC AFLWVVVAVA MAPLLVSPQT 
       210        220        230        240        250
VQTNHTVVCL QLYREKASHH ALVSLAVAFT FPFITTVTCY LLIIRSLRQG 
       260        270        280        290        300
LRVEKRLKTK AVRMIAIVLA IFLVCFVPYH VNRSVYVLHY RSHGASCATQ 
       310        320        330        340        350
RILALANRIT SCLTSLNGAL DPIMYFFVAE KFRHALCNLL CGKRLKGPPP 
       360 
SFEGKTNESS LSAKSEL

Length:367

Mass (Da):40,989

Last modified:May 27, 2002 - v2

Checksum:ⁱ132FBE97BE83C60C

Isoform 2 (identifier: Q13304-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-28: Missing.

« Hide

        10         20         30         40         50
MNGLEVAPPG LITNFSLATA EQCGQETPLE NMLFASFYLL DFILALVGNT 
        60         70         80         90        100
LALWLFIRDH KSGTPANVFL MHLAVADLSC VLVLPTRLVY HFSGNHWPFG 
       110        120        130        140        150
EIACRLTGFL FYLNMYASIY FLTCISADRF LAIVHPVKSL KLRRPLYAHL 
       160        170        180        190        200
ACAFLWVVVA VAMAPLLVSP QTVQTNHTVV CLQLYREKAS HHALVSLAVA 
       210        220        230        240        250
FTFPFITTVT CYLLIIRSLR QGLRVEKRLK TKAVRMIAIV LAIFLVCFVP 
       260        270        280        290        300
YHVNRSVYVL HYRSHGASCA TQRILALANR ITSCLTSLNG ALDPIMYFFV 
       310        320        330 
AEKFRHALCN LLCGKRLKGP PPSFEGKTNE SSLSAKSEL

Show »

Length:339

Mass (Da):37,827

Checksum:ⁱBD2AEDB2FEBF15E1

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	C9JWY5	C9JWY5_HUMAN		Uracil nucleotide/cysteinyl leukotr... Uracil nucleotide/cysteinyl leukotriene receptor	GPR17	136	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	83	L → F in AAH31653 (PubMed:15489334).Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_001987	1 – 28	Missing in isoform 2. 3 PublicationsAdd BLAST		28

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U33447 Genomic DNA Translation: AAB16746.1 Y12546 mRNA Translation: CAA73144.1 Z94154 mRNA Translation: CAB08107.1 Z94155 mRNA Translation: CAB08108.1 AK292725 mRNA Translation: BAF85414.1 AK313949 mRNA Translation: BAG36667.1 CH471103 Genomic DNA Translation: EAW95337.1 BC031653 mRNA Translation: AAH31653.1 BC039595 mRNA No translation available.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS2148.1 [Q13304-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001154887.1, NM_001161415.1 [Q13304-1] NP_001154888.1, NM_001161416.1 [Q13304-2] NP_001154889.1, NM_001161417.1 [Q13304-2] NP_005282.1, NM_005291.2 [Q13304-1] XP_016859322.1, XM_017003833.1 [Q13304-1]
UniGeneⁱ	Hs.46453 Hs.736277

Genome annotation databases

Ensemblⁱ	ENST00000272644; ENSP00000272644; ENSG00000144230 [Q13304-1] ENST00000393018; ENSP00000376741; ENSG00000144230 [Q13304-1] ENST00000544369; ENSP00000442982; ENSG00000144230 [Q13304-1]
GeneIDⁱ	2840
KEGGⁱ	hsa:2840
UCSC genome browser More...UCSCⁱ	uc002tpc.4 human [Q13304-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q13304	G protein-coupled receptor 17 isoform b		HUMAN		339	UniRef100_Q13304
Isoform 2 of Uracil nucleotide/cysteinyl leukotriene receptor		HUMAN		339
Uracil nucleotide/cysteinyl leukotriene receptor (Fragment)		HUMAN		136

Protein	Similar proteins		Species	Score	Length	Source
Q13304	G protein-coupled receptor 17 isoform b		HUMAN		339	UniRef90_Q13304
Uncharacterized protein		COLAP		371
Uncharacterized protein		PAPAN		371
Uncharacterized protein		CERAT		371
Uncharacterized protein		RHIRO		371
+32

Protein	Similar proteins		Species	Score	Length	Source
Q13304	G protein-coupled receptor 17 isoform b		HUMAN		339	UniRef50_Q13304
Uncharacterized protein		MACNE		371
Uncharacterized protein		COLAP		371
G protein-coupled receptor 17		CHLSB		371
Uncharacterized protein		PAPAN		371
+55

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U33447 Genomic DNA Translation: AAB16746.1 Y12546 mRNA Translation: CAA73144.1 Z94154 mRNA Translation: CAB08107.1 Z94155 mRNA Translation: CAB08108.1 AK292725 mRNA Translation: BAF85414.1 AK313949 mRNA Translation: BAG36667.1 CH471103 Genomic DNA Translation: EAW95337.1 BC031653 mRNA Translation: AAH31653.1 BC039595 mRNA No translation available.
CCDSⁱ	CCDS2148.1 [Q13304-1]
RefSeqⁱ	NP_001154887.1, NM_001161415.1 [Q13304-1] NP_001154888.1, NM_001161416.1 [Q13304-2] NP_001154889.1, NM_001161417.1 [Q13304-2] NP_005282.1, NM_005291.2 [Q13304-1] XP_016859322.1, XM_017003833.1 [Q13304-1]
UniGeneⁱ	Hs.46453 Hs.736277

3D structure databases

ProteinModelPortalⁱ	Q13304
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	109099, 1 interactor
STRINGⁱ	9606.ENSP00000272644

Chemistry databases

BindingDBⁱ	Q13304
ChEMBLⁱ	CHEMBL1075162
GuidetoPHARMACOLOGYⁱ	88

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

PTM databases

iPTMnetⁱ	Q13304
PhosphoSitePlusⁱ	Q13304

Polymorphism and mutation databases

BioMutaⁱ	GPR17
DMDMⁱ	21264435

Proteomic databases

PaxDbⁱ	Q13304
PeptideAtlasⁱ	Q13304
PRIDEⁱ	Q13304
ProteomicsDBⁱ	59291 59292 [Q13304-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	2840
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000272644; ENSP00000272644; ENSG00000144230 [Q13304-1] ENST00000393018; ENSP00000376741; ENSG00000144230 [Q13304-1] ENST00000544369; ENSP00000442982; ENSG00000144230 [Q13304-1]
GeneIDⁱ	2840
KEGGⁱ	hsa:2840
UCSCⁱ	uc002tpc.4 human [Q13304-1]

Organism-specific databases

CTDⁱ	2840
DisGeNETⁱ	2840
EuPathDBⁱ	HostDB:ENSG00000144230.16
GeneCardsⁱ	GPR17
HGNCⁱ	HGNC:4471 GPR17
HPAⁱ	HPA029766
MIMⁱ	603071 gene
neXtProtⁱ	NX_Q13304
OpenTargetsⁱ	ENSG00000144230
PharmGKBⁱ	PA28859
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IGZC Eukaryota ENOG41110RZ LUCA
GeneTreeⁱ	ENSGT00920000148939
HOGENOMⁱ	HOG000236328
HOVERGENⁱ	HBG102010
InParanoidⁱ	Q13304
KOⁱ	K08404
OMAⁱ	FSGNHWP
OrthoDBⁱ	EOG091G0A8K
PhylomeDBⁱ	Q13304
TreeFamⁱ	TF330775

Enzyme and pathway databases

Reactomeⁱ	R-HSA-391906 Leukotriene receptors R-HSA-416476 G alpha (q) signalling events R-HSA-417957 P2Y receptors R-HSA-418594 G alpha (i) signalling events

Reactomeⁱ

R-HSA-391906 Leukotriene receptors
R-HSA-416476 G alpha (q) signalling events
R-HSA-417957 P2Y receptors
R-HSA-418594 G alpha (i) signalling events

Miscellaneous databases

GeneWikiⁱ	GPR17
GenomeRNAiⁱ	2840
Protein Ontology More...PROⁱ	PR:Q13304
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000144230 Expressed in 113 organ(s), highest expression level in heart left ventricle
CleanExⁱ	HS_GPR17
ExpressionAtlasⁱ	Q13304 baseline and differential
Genevisibleⁱ	Q13304 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM
Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	GPR17_HUMAN
Accessionⁱ	Q13304Primary (citable) accession number: Q13304 Secondary accession number(s): A8K9L0 , B2R9X0, Q8N5S7, Q9UDZ6, Q9UE21
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
	Last sequence update:	May 27, 2002
	Last modified:	November 7, 2018
	This is version 149 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 2
Human chromosome 2: entries, gene names and cross-references to MIM
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q13304 (GPR17_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Uracil nucleotide/cysteinyl leukotriene receptor

GPR17

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Plasma Membrane

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ