UniProtKB - Q13136 (LIPA1_HUMAN)
Liprin-alpha-1
PPFIA1
Functioni
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
1 PublicationGO - Biological processi
- cell-matrix adhesion Source: ProtInc
- negative regulation of protein localization to plasma membrane Source: MGI
- negative regulation of stress fiber assembly Source: MGI
- signal transduction Source: ProtInc
- synapse organization Source: GO_Central
Enzyme and pathway databases
PathwayCommonsi | Q13136 |
Reactomei | R-HSA-181429, Serotonin Neurotransmitter Release Cycle R-HSA-181430, Norepinephrine Neurotransmitter Release Cycle R-HSA-210500, Glutamate Neurotransmitter Release Cycle R-HSA-212676, Dopamine Neurotransmitter Release Cycle R-HSA-264642, Acetylcholine Neurotransmitter Release Cycle R-HSA-388844, Receptor-type tyrosine-protein phosphatases |
SignaLinki | Q13136 |
SIGNORi | Q13136 |
Names & Taxonomyi
Protein namesi | Recommended name: Liprin-alpha-1Alternative name(s): LAR-interacting protein 1 Short name: LIP-1 Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1 Short name: PTPRF-interacting protein alpha-1 |
Gene namesi | Name:PPFIA1 Synonyms:LIP1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:9245, PPFIA1 |
MIMi | 611054, gene |
neXtProti | NX_Q13136 |
VEuPathDBi | HostDB:ENSG00000131626 |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Note: Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus.
Cytosol
- cytosol Source: HPA
Other locations
- axon Source: Ensembl
- cytoplasm Source: ProtInc
- dendrite Source: Ensembl
- focal adhesion Source: HPA
- presynaptic active zone Source: GO_Central
- protein-containing complex Source: Ensembl
Keywords - Cellular componenti
CytoplasmPathology & Biotechi
Organism-specific databases
DisGeNETi | 8500 |
OpenTargetsi | ENSG00000131626 |
PharmGKBi | PA33566 |
Miscellaneous databases
Pharosi | Q13136, Tbio |
Genetic variation databases
BioMutai | PPFIA1 |
DMDMi | 42558969 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000191026 | 1 – 1202 | Liprin-alpha-1Add BLAST | 1202 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 150 | PhosphoserineCombined sources | 1 | |
Modified residuei | 230 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 239 | PhosphoserineCombined sources | 1 | |
Modified residuei | 242 | PhosphoserineCombined sources | 1 | |
Modified residuei | 244 | PhosphoserineCombined sources | 1 | |
Modified residuei | 448 | PhosphoserineCombined sources | 1 | |
Modified residuei | 666 | PhosphoserineCombined sources | 1 | |
Modified residuei | 668 | PhosphoserineCombined sources | 1 | |
Modified residuei | 693 | PhosphoserineCombined sources | 1 | |
Modified residuei | 761 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 763 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1133 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1159 | PhosphothreonineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q13136 |
jPOSTi | Q13136 |
MassIVEi | Q13136 |
MaxQBi | Q13136 |
PaxDbi | Q13136 |
PeptideAtlasi | Q13136 |
PRIDEi | Q13136 |
ProteomicsDBi | 59184 [Q13136-1] 59185 [Q13136-2] |
PTM databases
GlyGeni | Q13136, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q13136 |
MetOSitei | Q13136 |
PhosphoSitePlusi | Q13136 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000131626, Expressed in sural nerve and 239 other tissues |
ExpressionAtlasi | Q13136, baseline and differential |
Genevisiblei | Q13136, HS |
Organism-specific databases
HPAi | ENSG00000131626, Low tissue specificity |
Interactioni
Subunit structurei
Forms homodimers and heterodimers with liprins-alpha and liprins-beta.
Interacts with the second PTPase domain of PTPRD, PTPRF and PTPRS.
Interacts with GIT1, KIF1A and GRIP1 (By similarity).
By similarityBinary interactionsi
Q13136
Protein-protein interaction databases
BioGRIDi | 114072, 145 interactors |
ELMi | Q13136 |
IntActi | Q13136, 64 interactors |
MINTi | Q13136 |
STRINGi | 9606.ENSP00000253925 |
Miscellaneous databases
RNActi | Q13136, protein |
Structurei
Secondary structure
3D structure databases
AlphaFoldDBi | Q13136 |
SMRi | Q13136 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 878 – 944 | SAM 1PROSITE-ProRule annotationAdd BLAST | 67 | |
Domaini | 963 – 1027 | SAM 2PROSITE-ProRule annotationAdd BLAST | 65 | |
Domaini | 1051 – 1120 | SAM 3PROSITE-ProRule annotationAdd BLAST | 70 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 33 | DisorderedSequence analysisAdd BLAST | 33 | |
Regioni | 224 – 245 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 426 – 446 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 651 – 855 | DisorderedSequence analysisAdd BLAST | 205 | |
Regioni | 1163 – 1202 | DisorderedSequence analysisAdd BLAST | 40 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 34 – 141 | Sequence analysisAdd BLAST | 108 | |
Coiled coili | 176 – 214 | Sequence analysisAdd BLAST | 39 | |
Coiled coili | 249 – 521 | Sequence analysisAdd BLAST | 273 | |
Coiled coili | 623 – 669 | Sequence analysisAdd BLAST | 47 | |
Coiled coili | 847 – 871 | Sequence analysisAdd BLAST | 25 | |
Coiled coili | 1021 – 1050 | Sequence analysisAdd BLAST | 30 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 224 – 239 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 681 – 699 | Polar residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 749 – 772 | Basic and acidic residuesSequence analysisAdd BLAST | 24 | |
Compositional biasi | 773 – 793 | Polar residuesSequence analysisAdd BLAST | 21 | |
Compositional biasi | 831 – 845 | Polar residuesSequence analysisAdd BLAST | 15 |
Domaini
Sequence similaritiesi
Keywords - Domaini
Coiled coil, RepeatPhylogenomic databases
eggNOGi | KOG0249, Eukaryota |
GeneTreei | ENSGT01030000234715 |
HOGENOMi | CLU_006923_0_0_1 |
InParanoidi | Q13136 |
OMAi | KERMVAM |
OrthoDBi | 440941at2759 |
PhylomeDBi | Q13136 |
TreeFami | TF314207 |
Family and domain databases
CDDi | cd09562, SAM_liprin-alpha1_2_3_4_repeat1, 1 hit cd09565, SAM_liprin-alpha1_2_3_4_repeat2, 1 hit cd09568, SAM_liprin-alpha1_2_3_4_repeat3, 1 hit |
Gene3Di | 1.10.150.50, 3 hits |
InterProi | View protein in InterPro IPR029515, Liprin IPR037620, Liprin-alpha_SAM_rpt_1 IPR037621, Liprin-alpha_SAM_rpt_2 IPR037622, Liprin-alpha_SAM_rpt_3 IPR030438, PPFIA1 IPR001660, SAM IPR013761, SAM/pointed_sf |
PANTHERi | PTHR12587, PTHR12587, 1 hit PTHR12587:SF15, PTHR12587:SF15, 1 hit |
Pfami | View protein in Pfam PF00536, SAM_1, 2 hits PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00454, SAM, 3 hits |
SUPFAMi | SSF47769, SSF47769, 3 hits |
PROSITEi | View protein in PROSITE PS50105, SAM_DOMAIN, 3 hits |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 13 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MMCEVMPTIS EAEGPPGGGG GHGSGSPSQP DADSHFEQLM VSMLEERDRL
60 70 80 90 100
LDTLRETQET LALTQGKLHE VGHERDSLQR QLNTALPQEF AALTKELNVC
110 120 130 140 150
REQLLEREEE IAELKAERNN TRLLLEHLEC LVSRHERSLR MTVVKRQAQS
160 170 180 190 200
PAGVSSEVEV LKALKSLFEH HKALDEKVRE RLRVALERCS LLEEELGATH
210 220 230 240 250
KELMILKEQN NQKKTLTDGV LDINHEQENT PSTSGKRSSD GSLSHEEDLA
260 270 280 290 300
KVIELQEIIS KQSREQSQMK ERLASLSSHV TELEEDLDTA RKDLIKSEEM
310 320 330 340 350
NTKLQRDVRE AMAQKEDMEE RITTLEKRYL AAQREATSVH DLNDKLENEI
360 370 380 390 400
ANKDSMHRQT EDKNRQLQER LELAEQKLQQ TLRKAETLPE VEAELAQRVA
410 420 430 440 450
ALSKAEERHG NIEERLRQME AQLEEKNQEL QRARQREKMN EEHNKRLSDT
460 470 480 490 500
VDKLLSESNE RLQLHLKERM AALEDKNSLL REVESAKKQL EETQHDKDQL
510 520 530 540 550
VLNIEALRAE LDHMRLRGAS LHHGRPHLGS VPDFRFPMAD GHTDSYSTSA
560 570 580 590 600
VLRRPQKGRL AALRDEPSKV QTLNEQDWER AQQASVLANV AQAFESDADV
610 620 630 640 650
SDGEDDRDTL LSSVDLLSPS GQADAHTLAM MLQEQLDAIN KEIRLIQEEK
660 670 680 690 700
ENTEQRAEEI ESRVGSGSLD NLGRFRSMSS IPPYPASSLA SSSPPGSGRS
710 720 730 740 750
TPRRIPHSPA REVDRLGVMT LLPPSREEVR DDKTTIKCET SPPSSPRALR
760 770 780 790 800
LDRLHKGALH TVSHEDIRDI RNSTGSQDGP VSNPSSSNSS QDSLHKAPKK
810 820 830 840 850
KGIKSSIGRL FGKKEKGRPG QTGKEALGQA GVSETDNSSQ DALGLSKLGG
860 870 880 890 900
QAEKNRKLQK KHELLEEARR QGLPFAQWDG PTVVVWLELW VGMPAWYVAA
910 920 930 940 950
CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE IMSLTSPSAP
960 970 980 990 1000
PTSRTTLAYG DMNHEWIGNE WLPSLGLPQY RSYFMECLVD ARMLDHLTKK
1010 1020 1030 1040 1050
DLRGQLKMVD SFHRNSFQCG IMCLRRLNYD RKELERKREE SQSEIKDVLV
1060 1070 1080 1090 1100
WSNDRVIRWI LSIGLKEYAN NLIESGVHGA LLALDETFDF SALALLLQIP
1110 1120 1130 1140 1150
TQNTQARAVL EREFNNLLVM GTDRRFDEDD DKSFRRAPSW RKKFRPKDIR
1160 1170 1180 1190 1200
GLAAGSAETL PANFRVTSSM SSPSMQPKKM QMDGNVSGTQ RLDSATVRTY
SC
Computationally mapped potential isoform sequencesi
There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2R8Y7R9 | A0A2R8Y7R9_HUMAN | Liprin-alpha-1 | PPFIA1 | 1,224 | Annotation score: | ||
A0A1B0GVT3 | A0A1B0GVT3_HUMAN | Liprin-alpha-1 | PPFIA1 | 271 | Annotation score: | ||
H0YDW2 | H0YDW2_HUMAN | Liprin-alpha-1 | PPFIA1 | 389 | Annotation score: | ||
E9PJZ7 | E9PJZ7_HUMAN | Liprin-alpha-1 | PPFIA1 | 583 | Annotation score: | ||
H0YD72 | H0YD72_HUMAN | Liprin-alpha-1 | PPFIA1 | 237 | Annotation score: | ||
E9PPF6 | E9PPF6_HUMAN | Liprin-alpha-1 | PPFIA1 | 158 | Annotation score: | ||
E9PID5 | E9PID5_HUMAN | Liprin-alpha-1 | PPFIA1 | 99 | Annotation score: | ||
H0YEF9 | H0YEF9_HUMAN | Liprin-alpha-1 | PPFIA1 | 387 | Annotation score: | ||
H0YDZ8 | H0YDZ8_HUMAN | Liprin-alpha-1 | PPFIA1 | 98 | Annotation score: | ||
H0YEK0 | H0YEK0_HUMAN | Liprin-alpha-1 | PPFIA1 | 46 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 492 | E → G in AAH34046 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 555 | P → T in AAH34046 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 672 – 674 | LGR → EFG in BAA08353 (Ref. 4) Curated | 3 | |
Sequence conflicti | 800 – 801 | KK → EE in BAA08353 (Ref. 4) Curated | 2 | |
Sequence conflicti | 866 | E → G in AAH34046 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 994 | L → Q in BAA08353 (Ref. 4) Curated | 1 | |
Sequence conflicti | 1023 | C → S in BAA08353 (Ref. 4) Curated | 1 | |
Sequence conflicti | 1044 | E → EVRV in BAA08353 (Ref. 4) Curated | 1 | |
Sequence conflicti | 1121 – 1123 | GTD → PEF in BAA08353 (Ref. 4) Curated | 3 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_017756 | 71 | V → I. Corresponds to variant dbSNP:rs546502Ensembl. | 1 | |
Natural variantiVAR_049998 | 1072 | L → F. Corresponds to variant dbSNP:rs11236045Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_009391 | 1185 – 1202 | NVSGT…RTYSC → M in isoform 2. 1 PublicationAdd BLAST | 18 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U22815 mRNA Translation: AAC50172.1 U22816 mRNA Translation: AAC50173.1 AP002336 Genomic DNA No translation available. BC034046 mRNA Translation: AAH34046.1 D49354 mRNA Translation: BAA08353.1 Frameshift. |
CCDSi | CCDS31627.1 [Q13136-1] CCDS31628.1 [Q13136-2] |
PIRi | S55553 |
RefSeqi | NP_003617.1, NM_003626.3 [Q13136-1] NP_803172.1, NM_177423.2 [Q13136-2] |
Genome annotation databases
Ensembli | ENST00000253925.12; ENSP00000253925.7; ENSG00000131626.19 ENST00000389547.7; ENSP00000374198.3; ENSG00000131626.19 [Q13136-2] |
GeneIDi | 8500 |
KEGGi | hsa:8500 |
MANE-Selecti | ENST00000253925.12; ENSP00000253925.7; NM_003626.5; NP_003617.1 |
UCSCi | uc001opn.3, human [Q13136-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U22815 mRNA Translation: AAC50172.1 U22816 mRNA Translation: AAC50173.1 AP002336 Genomic DNA No translation available. BC034046 mRNA Translation: AAH34046.1 D49354 mRNA Translation: BAA08353.1 Frameshift. |
CCDSi | CCDS31627.1 [Q13136-1] CCDS31628.1 [Q13136-2] |
PIRi | S55553 |
RefSeqi | NP_003617.1, NM_003626.3 [Q13136-1] NP_803172.1, NM_177423.2 [Q13136-2] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1N7F | X-ray | 1.80 | C/D | 1195-1202 | [»] | |
AlphaFoldDBi | Q13136 | |||||
SMRi | Q13136 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 114072, 145 interactors |
ELMi | Q13136 |
IntActi | Q13136, 64 interactors |
MINTi | Q13136 |
STRINGi | 9606.ENSP00000253925 |
PTM databases
GlyGeni | Q13136, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q13136 |
MetOSitei | Q13136 |
PhosphoSitePlusi | Q13136 |
Genetic variation databases
BioMutai | PPFIA1 |
DMDMi | 42558969 |
Proteomic databases
EPDi | Q13136 |
jPOSTi | Q13136 |
MassIVEi | Q13136 |
MaxQBi | Q13136 |
PaxDbi | Q13136 |
PeptideAtlasi | Q13136 |
PRIDEi | Q13136 |
ProteomicsDBi | 59184 [Q13136-1] 59185 [Q13136-2] |
Protocols and materials databases
Antibodypediai | 30679, 196 antibodies from 31 providers |
DNASUi | 8500 |
Genome annotation databases
Ensembli | ENST00000253925.12; ENSP00000253925.7; ENSG00000131626.19 ENST00000389547.7; ENSP00000374198.3; ENSG00000131626.19 [Q13136-2] |
GeneIDi | 8500 |
KEGGi | hsa:8500 |
MANE-Selecti | ENST00000253925.12; ENSP00000253925.7; NM_003626.5; NP_003617.1 |
UCSCi | uc001opn.3, human [Q13136-1] |
Organism-specific databases
CTDi | 8500 |
DisGeNETi | 8500 |
GeneCardsi | PPFIA1 |
HGNCi | HGNC:9245, PPFIA1 |
HPAi | ENSG00000131626, Low tissue specificity |
MIMi | 611054, gene |
neXtProti | NX_Q13136 |
OpenTargetsi | ENSG00000131626 |
PharmGKBi | PA33566 |
VEuPathDBi | HostDB:ENSG00000131626 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0249, Eukaryota |
GeneTreei | ENSGT01030000234715 |
HOGENOMi | CLU_006923_0_0_1 |
InParanoidi | Q13136 |
OMAi | KERMVAM |
OrthoDBi | 440941at2759 |
PhylomeDBi | Q13136 |
TreeFami | TF314207 |
Enzyme and pathway databases
PathwayCommonsi | Q13136 |
Reactomei | R-HSA-181429, Serotonin Neurotransmitter Release Cycle R-HSA-181430, Norepinephrine Neurotransmitter Release Cycle R-HSA-210500, Glutamate Neurotransmitter Release Cycle R-HSA-212676, Dopamine Neurotransmitter Release Cycle R-HSA-264642, Acetylcholine Neurotransmitter Release Cycle R-HSA-388844, Receptor-type tyrosine-protein phosphatases |
SignaLinki | Q13136 |
SIGNORi | Q13136 |
Miscellaneous databases
BioGRID-ORCSi | 8500, 26 hits in 1082 CRISPR screens |
ChiTaRSi | PPFIA1, human |
GeneWikii | Liprin-alpha-1 |
GenomeRNAii | 8500 |
Pharosi | Q13136, Tbio |
PROi | PR:Q13136 |
RNActi | Q13136, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000131626, Expressed in sural nerve and 239 other tissues |
ExpressionAtlasi | Q13136, baseline and differential |
Genevisiblei | Q13136, HS |
Family and domain databases
CDDi | cd09562, SAM_liprin-alpha1_2_3_4_repeat1, 1 hit cd09565, SAM_liprin-alpha1_2_3_4_repeat2, 1 hit cd09568, SAM_liprin-alpha1_2_3_4_repeat3, 1 hit |
Gene3Di | 1.10.150.50, 3 hits |
InterProi | View protein in InterPro IPR029515, Liprin IPR037620, Liprin-alpha_SAM_rpt_1 IPR037621, Liprin-alpha_SAM_rpt_2 IPR037622, Liprin-alpha_SAM_rpt_3 IPR030438, PPFIA1 IPR001660, SAM IPR013761, SAM/pointed_sf |
PANTHERi | PTHR12587, PTHR12587, 1 hit PTHR12587:SF15, PTHR12587:SF15, 1 hit |
Pfami | View protein in Pfam PF00536, SAM_1, 2 hits PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00454, SAM, 3 hits |
SUPFAMi | SSF47769, SSF47769, 3 hits |
PROSITEi | View protein in PROSITE PS50105, SAM_DOMAIN, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | LIPA1_HUMAN | |
Accessioni | Q13136Primary (citable) accession number: Q13136 Secondary accession number(s): A6NLE3 Q8N4I2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 16, 2004 |
Last sequence update: | November 1, 1996 | |
Last modified: | May 25, 2022 | |
This is version 192 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families