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UniProtKB - Q13113 (PDZ1I_HUMAN)

Entry version 149 (23 Feb 2022)
Sequence version 1 (01 Nov 1996)
Previous versions | rss
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Protein

PDZK1-interacting protein 1

Gene

PDZK1IP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play an important role in tumor biology.

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q13113

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q13113

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PDZK1-interacting protein 1
Alternative name(s):
17 kDa membrane-associated protein
Protein DD96
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PDZK1IP1
Synonyms:MAP17
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:16887, PDZK1IP1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		607178, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q13113

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000162366

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei30 – 50HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		10158

Open Targets

More...OpenTargetsi		ENSG00000162366

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142671188

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q13113, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		PDZK1IP1

Domain mapping of disease mutations (DMDM)

More...DMDMi		6225642

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000582821 – 114PDZK1-interacting protein 1Add BLAST114

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei85PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q13113

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q13113

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q13113

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q13113

PeptideAtlas

More...PeptideAtlasi		Q13113

PRoteomics IDEntifications database

More...PRIDEi		Q13113

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		59164

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q13113

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q13113

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q13113

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at significant levels only in a single epithelial cell population, the proximal tubular epithelial cells of the kidney. Diffusely expressed in various carcinomas originating from kidney, colon, lung and breast.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000162366, Expressed in adult mammalian kidney and 164 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q13113, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000162366, Tissue enriched (kidney)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PDZK1.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q13113
With#Exp.IntAct
AGR3 [Q8TD06]3EBI-716063,EBI-3925742
AIG1 - isoform 1 [Q9NVV5-2]3EBI-716063,EBI-11957045
APOA2 [P02652]3EBI-716063,EBI-1171525
APOD [P05090]3EBI-716063,EBI-715495
APP [P05067]3EBI-716063,EBI-77613
APP - isoform APP305 [P05067-2]3EBI-716063,EBI-17264467
AQP2 [P41181]3EBI-716063,EBI-12701138
AQP6 [Q13520]3EBI-716063,EBI-13059134
ARL13B [Q3SXY8]3EBI-716063,EBI-11343438
ASGR1 [P07306]3EBI-716063,EBI-1172335
ATXN1 [P54253]6EBI-716063,EBI-930964
C2CD2L [O14523]3EBI-716063,EBI-12822627
CD81 [P60033]3EBI-716063,EBI-712921
CES1 - isoform 3 [P23141-3]3EBI-716063,EBI-12360993
CLDN19 - isoform 2 [Q8N6F1-2]3EBI-716063,EBI-12256978
CYB5B [O43169]3EBI-716063,EBI-1058710
CYBC1 [Q9BQA9]3EBI-716063,EBI-2680384
DNM2 - isoform 2 [P50570-2]3EBI-716063,EBI-10968534
EMC6 [Q9BV81]3EBI-716063,EBI-2820492
ERG28 [Q9UKR5]3EBI-716063,EBI-711490
FAM3C [Q92520]3EBI-716063,EBI-2876774
GALNT15 [Q8N3T1]3EBI-716063,EBI-3925203
GAST [P01350]3EBI-716063,EBI-3436637
GIMAP5 [Q96F15]3EBI-716063,EBI-6166686
GRM2 [Q14416]3EBI-716063,EBI-10232876
GYPA [P02724]3EBI-716063,EBI-702665
HMOX1 [P09601]3EBI-716063,EBI-2806151
HTT [P42858]21EBI-716063,EBI-466029
ICMT [O60725]3EBI-716063,EBI-11721771
IGFBP5 [P24593]3EBI-716063,EBI-720480
JAGN1 [Q8N5M9]3EBI-716063,EBI-10266796
LEPROTL1 [O95214]3EBI-716063,EBI-750776
LHFPL5 [Q8TAF8]3EBI-716063,EBI-2820517
MIP [P30301]3EBI-716063,EBI-8449636
MYADM [Q96S97]3EBI-716063,EBI-13301517
MYADML2 [A6NDP7]3EBI-716063,EBI-17641390
NRAC [Q8N912]3EBI-716063,EBI-12051377
NSG1 [P42857]3EBI-716063,EBI-6380741
OPTN [Q96CV9]3EBI-716063,EBI-748974
PEX16 [Q9Y5Y5]3EBI-716063,EBI-981985
PGAP2 - isoform 5 [Q9UHJ9-5]3EBI-716063,EBI-12092917
PINK1 [Q9BXM7]3EBI-716063,EBI-2846068
PLP2 [Q04941]3EBI-716063,EBI-608347
PLPP4 [Q5VZY2]3EBI-716063,EBI-10485931
PLPP6 [Q8IY26]3EBI-716063,EBI-11721828
PMP22 [D3DTS7]3EBI-716063,EBI-25882629
PMP22 [Q01453]3EBI-716063,EBI-2845982
PRKN - isoform 5 [O60260-5]6EBI-716063,EBI-21251460
PSEN1 - isoform 2 [P49768-2]6EBI-716063,EBI-11047108
PSEN2 [P49810]3EBI-716063,EBI-2010251
RPRM [Q9NS64]3EBI-716063,EBI-1052363
RTP2 [Q5QGT7]3EBI-716063,EBI-10244780
SDCBP [O00560]3EBI-716063,EBI-727004
SFTPC [P11686]3EBI-716063,EBI-10197617
SFXN2 [Q96NB2]3EBI-716063,EBI-6381136
SLC35B1 [P78383]3EBI-716063,EBI-12147661
SLC35B4 [Q969S0]3EBI-716063,EBI-10281213
SNCA [P37840]3EBI-716063,EBI-985879
SOD1 [P00441]3EBI-716063,EBI-990792
STRIT1 [P0DN84]3EBI-716063,EBI-12200293
STX12 [Q86Y82]3EBI-716063,EBI-2691717
THBD [P07204]3EBI-716063,EBI-941422
TMEM101 [Q96IK0]3EBI-716063,EBI-3922699
TMEM107 [Q6UX40]3EBI-716063,EBI-12845616
TMEM109 [Q9BVC6]3EBI-716063,EBI-1057733
TMEM11 [P17152]3EBI-716063,EBI-723946
TMEM140 [Q9NV12]3EBI-716063,EBI-2844246
TMEM14A [Q9Y6G1]3EBI-716063,EBI-2800360
TMEM14B [Q9NUH8]3EBI-716063,EBI-8638294
TMEM14C [Q9P0S9]3EBI-716063,EBI-2339195
TMEM203 [Q969S6]3EBI-716063,EBI-12274070
TMEM39B - isoform 4 [Q9GZU3-4]3EBI-716063,EBI-17572471
TMEM65 [Q6PI78]3EBI-716063,EBI-6656213
TMEM86A [Q8N2M4]3EBI-716063,EBI-12015604
TMEM97 [Q5BJF2]3EBI-716063,EBI-12111910
TNFRSF10C [O14798]3EBI-716063,EBI-717441
TOR1A - isoform 2 [O14656-2]3EBI-716063,EBI-25847109
TSPO2 [Q5TGU0]3EBI-716063,EBI-12195249
TUSC5 [A5PKU2]3EBI-716063,EBI-11988865
UCHL1 [P09936]3EBI-716063,EBI-714860
UPK1B [O75841]3EBI-716063,EBI-12237619
VAMP3 [Q15836]3EBI-716063,EBI-722343
YIPF6 [Q96EC8]3EBI-716063,EBI-751210

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		115460, 77 interactors

Protein interaction database and analysis system

More...IntActi		Q13113, 86 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000294338

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q13113, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni94 – 114DisorderedSequence analysisAdd BLAST21

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502SAPW, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000154660

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_168651_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q13113

Identification of Orthologs from Complete Genome Data

More...OMAi		NFRSSEH

Database of Orthologous Groups

More...OrthoDBi		1588365at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q13113

TreeFam database of animal gene trees

More...TreeFami		TF328829

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026628, PDZK-int_prot1
IPR031627, PDZK1IP1/SMIM24

The PANTHER Classification System

More...PANTHERi		PTHR15296, PTHR15296, 1 hit
PTHR15296:SF0, PTHR15296:SF0, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15807, MAP17, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q13113-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSALSLLILG LLTAVPPASC QQGLGNLQPW MQGLIAVAVF LVLVAIAFAV 
        60         70         80         90        100
NHFWCQEEPE PAHMILTVGN KADGVLVGTD GRYSSMAASF RSSEHENAYE 
       110 
NVPEEEGKVR STPM
Length:114
Mass (Da):12,227
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7DEB64C3AF78CB18
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti13T → M in AAH12303 (PubMed:15489334).Curated1
Sequence conflicti51N → K in AAH12303 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U21049 mRNA Translation: AAA92690.1
CR450304 mRNA Translation: CAG29300.1
AL135960 Genomic DNA Translation: CAB72104.1
CH471059 Genomic DNA Translation: EAX06878.1
BC012303 mRNA Translation: AAH12303.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS546.1

NCBI Reference Sequences

More...RefSeqi		NP_005755.1, NM_005764.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000294338; ENSP00000294338; ENSG00000162366
ENST00000371885; ENSP00000360952; ENSG00000162366

Database of genes from NCBI RefSeq genomes

More...GeneIDi		10158

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:10158

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000294338.7; ENSP00000294338.2; NM_005764.4; NP_005755.1

UCSC genome browser

More...UCSCi		uc001cqw.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U21049 mRNA Translation: AAA92690.1
CR450304 mRNA Translation: CAG29300.1
AL135960 Genomic DNA Translation: CAB72104.1
CH471059 Genomic DNA Translation: EAX06878.1
BC012303 mRNA Translation: AAH12303.1
CCDSiCCDS546.1
RefSeqiNP_005755.1, NM_005764.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
7FENelectron microscopy2.95B1-56[»]
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi115460, 77 interactors
IntActiQ13113, 86 interactors
STRINGi9606.ENSP00000294338

PTM databases

iPTMnetiQ13113
PhosphoSitePlusiQ13113
SwissPalmiQ13113

Genetic variation databases

BioMutaiPDZK1IP1
DMDMi6225642

Proteomic databases

EPDiQ13113
jPOSTiQ13113
MassIVEiQ13113
PaxDbiQ13113
PeptideAtlasiQ13113
PRIDEiQ13113
ProteomicsDBi59164

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2658, 29 antibodies from 12 providers

The DNASU plasmid repository

More...DNASUi		10158

Genome annotation databases

EnsembliENST00000294338; ENSP00000294338; ENSG00000162366
ENST00000371885; ENSP00000360952; ENSG00000162366
GeneIDi10158
KEGGihsa:10158
MANE-SelectiENST00000294338.7; ENSP00000294338.2; NM_005764.4; NP_005755.1
UCSCiuc001cqw.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		10158
DisGeNETi10158

GeneCards: human genes, protein and diseases

More...GeneCardsi		PDZK1IP1
HGNCiHGNC:16887, PDZK1IP1
HPAiENSG00000162366, Tissue enriched (kidney)
MIMi607178, gene
neXtProtiNX_Q13113
OpenTargetsiENSG00000162366
PharmGKBiPA142671188
VEuPathDBiHostDB:ENSG00000162366

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502SAPW, Eukaryota
GeneTreeiENSGT00940000154660
HOGENOMiCLU_168651_0_0_1
InParanoidiQ13113
OMAiNFRSSEH
OrthoDBi1588365at2759
PhylomeDBiQ13113
TreeFamiTF328829

Enzyme and pathway databases

PathwayCommonsiQ13113
SignaLinkiQ13113

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		10158, 37 hits in 1029 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		PDZK1IP1, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		PDZK1IP1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		10158
PharosiQ13113, Tbio

Protein Ontology

More...PROi		PR:Q13113
RNActiQ13113, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000162366, Expressed in adult mammalian kidney and 164 other tissues
GenevisibleiQ13113, HS

Family and domain databases

InterProiView protein in InterPro
IPR026628, PDZK-int_prot1
IPR031627, PDZK1IP1/SMIM24
PANTHERiPTHR15296, PTHR15296, 1 hit
PTHR15296:SF0, PTHR15296:SF0, 1 hit
PfamiView protein in Pfam
PF15807, MAP17, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPDZ1I_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q13113
Secondary accession number(s): Q6ICT9, Q96EI1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: February 23, 2022
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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