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Entry version 171 (17 Jun 2020)
Sequence version 3 (03 Apr 2007)
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Protein

Zinc finger protein 154

Gene

ZNF154

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri89 – 111C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri133 – 155C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri161 – 183C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri189 – 211C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri217 – 239C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri245 – 267C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri273 – 295C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri301 – 323C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri329 – 351C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri357 – 379C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri385 – 407C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri413 – 435C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • DNA-binding transcription factor activity Source: UniProtKB
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 154
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF154
Synonyms:KIAA2003
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000179909.15

Human Gene Nomenclature Database

More...
HGNCi
HGNC:12939 ZNF154

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604085 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q13106

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7710

Open Targets

More...
OpenTargetsi
ENSG00000179909

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37523

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q13106 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF154

Domain mapping of disease mutations (DMDM)

More...
DMDMi
143811477

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000474301 – 437Zinc finger protein 154Add BLAST437

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q13106

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q13106

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q13106

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q13106

PeptideAtlas

More...
PeptideAtlasi
Q13106

PRoteomics IDEntifications database

More...
PRIDEi
Q13106

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
59157

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q13106

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q13106

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000179909 Expressed in lung and 93 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q13106 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q13106 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000179909 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q13106, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000421258

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q13106 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q13106

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini14 – 88KRABPROSITE-ProRule annotationAdd BLAST75

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri89 – 111C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri133 – 155C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri161 – 183C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri189 – 211C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri217 – 239C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri245 – 267C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri273 – 295C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri301 – 323C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri329 – 351C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri357 – 379C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri385 – 407C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri413 – 435C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154734

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_0_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q13106

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
RGKTHYN

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q13106

TreeFam database of animal gene trees

More...
TreeFami
TF339848

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q13106-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAATLRTPT QGTVTFEDVA VHFSWEEWGL LDEAQRCLYR DVMLENLALL
60 70 80 90 100
TSLDVHHQKQ HLGEKHFRSN VGRALFVKTC TFHVSGEPST CREVGKDFLA
110 120 130 140 150
KLGFLHQQAA HTGEQSNSKS DGGAISHRGK THYNCGEHTK AFSGKHTLVQ
160 170 180 190 200
QQRTLTTERC YICSECGKSF SKSYSLNDHW RLHTGEKPYE CRECGKSFRQ
210 220 230 240 250
SSSLIQHRRV HTAVRPHECD ECGKLFSNKS NLIKHRRVHT GERPYECSEC
260 270 280 290 300
GKSFSQRSAL LQHRGVHTGE RPYECSECGK FFTYHSSLIK HQKVHSGSRP
310 320 330 340 350
YECSECGKSF SQNSSLIEHH RVHTGERPYK CSECGKSFSQ RSALLQHRGV
360 370 380 390 400
HTGERPYECS ECGKFFPYSS SLRKHQRVHT GSRPYECSEC GKSFTQNSGL
410 420 430
IKHRRVHTGE KPYECTECGK SFSHNSSLIK HQRIHSR
Length:437
Mass (Da):49,865
Last modified:April 3, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i37469112DC85BFEB
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC23100 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti3A → V in BAC03839 (PubMed:14702039).Curated1
Sequence conflicti296S → I in BAC03839 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06067857H → R2 PublicationsCorresponds to variant dbSNP:rs34282745Ensembl.1
Natural variantiVAR_052779122G → V. Corresponds to variant dbSNP:rs2074078Ensembl.1
Natural variantiVAR_052780182L → V. Corresponds to variant dbSNP:rs2188736Ensembl.1
Natural variantiVAR_052781384P → L. Corresponds to variant dbSNP:rs34746514Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK092261 mRNA Translation: BAC03839.1
AB095924 mRNA Translation: BAC23100.1 Different initiation.
BC152404 mRNA Translation: AAI52405.1
BC152426 mRNA Translation: AAI52427.1
BC152561 mRNA Translation: AAI52562.1
U20648 mRNA Translation: AAC50257.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS42639.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I38941

NCBI Reference Sequences

More...
RefSeqi
NP_001078853.1, NM_001085384.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000451275; ENSP00000469633; ENSG00000179909
ENST00000512439; ENSP00000421258; ENSG00000179909

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7710

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7710

UCSC genome browser

More...
UCSCi
uc061dmm.1 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK092261 mRNA Translation: BAC03839.1
AB095924 mRNA Translation: BAC23100.1 Different initiation.
BC152404 mRNA Translation: AAI52405.1
BC152426 mRNA Translation: AAI52427.1
BC152561 mRNA Translation: AAI52562.1
U20648 mRNA Translation: AAC50257.1
CCDSiCCDS42639.1
PIRiI38941
RefSeqiNP_001078853.1, NM_001085384.2

3D structure databases

SMRiQ13106
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ13106, 1 interactor
STRINGi9606.ENSP00000421258

PTM databases

iPTMnetiQ13106
PhosphoSitePlusiQ13106

Polymorphism and mutation databases

BioMutaiZNF154
DMDMi143811477

Proteomic databases

jPOSTiQ13106
MassIVEiQ13106
MaxQBiQ13106
PaxDbiQ13106
PeptideAtlasiQ13106
PRIDEiQ13106
ProteomicsDBi59157

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33286 90 antibodies

The DNASU plasmid repository

More...
DNASUi
7710

Genome annotation databases

EnsembliENST00000451275; ENSP00000469633; ENSG00000179909
ENST00000512439; ENSP00000421258; ENSG00000179909
GeneIDi7710
KEGGihsa:7710
UCSCiuc061dmm.1 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7710
DisGeNETi7710
EuPathDBiHostDB:ENSG00000179909.15

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF154
HGNCiHGNC:12939 ZNF154
HPAiENSG00000179909 Low tissue specificity
MIMi604085 gene
neXtProtiNX_Q13106
OpenTargetsiENSG00000179909
PharmGKBiPA37523

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000154734
HOGENOMiCLU_002678_0_2_1
InParanoidiQ13106
KOiK09228
OMAiRGKTHYN
OrthoDBi1318335at2759
PhylomeDBiQ13106
TreeFamiTF339848

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
7710 5 hits in 807 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF154 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
7710
PharosiQ13106 Tdark

Protein Ontology

More...
PROi
PR:Q13106
RNActiQ13106 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000179909 Expressed in lung and 93 other tissues
ExpressionAtlasiQ13106 baseline and differential
GenevisibleiQ13106 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 10 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 10 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN154_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q13106
Secondary accession number(s): A7MCY3, Q8IVG7, Q8NAR0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: April 3, 2007
Last modified: June 17, 2020
This is version 171 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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