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Entry version 161 (18 Sep 2019)
Sequence version 4 (24 Jan 2006)
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Protein

39S ribosomal protein L28, mitochondrial

Gene

MRPL28

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Potentially represents an important therapeutic reagent for HLA-A24 patients. This antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290 in the context of HLA-A24.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5368286 Mitochondrial translation initiation
R-HSA-5389840 Mitochondrial translation elongation
R-HSA-5419276 Mitochondrial translation termination

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
39S ribosomal protein L28, mitochondrial
Short name:
L28mt
Short name:
MRP-L28
Alternative name(s):
Melanoma antigen p15
Melanoma-associated antigen recognized by T-lymphocytes
Mitochondrial large ribosomal subunit protein bL28m1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MRPL28
Synonyms:MAAT1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14484 MRPL28

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604853 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q13084

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10573

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30515

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q13084

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MRPL28

Domain mapping of disease mutations (DMDM)

More...
DMDMi
85695426

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 55MitochondrionBy similarityAdd BLAST55
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003050656 – 25639S ribosomal protein L28, mitochondrialAdd BLAST201

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q13084

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q13084

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q13084

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q13084

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q13084

PeptideAtlas

More...
PeptideAtlasi
Q13084

PRoteomics IDEntifications database

More...
PRIDEi
Q13084

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
59138

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q13084

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q13084

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q13084

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Found in a variety of normal tissues including spleen, testes, thymus, liver, kidney, brain, adrenal, lung and retinal tissue.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000086504 Expressed in 220 organ(s), highest expression level in apex of heart

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q13084 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q13084 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB033542
HPA030594
HPA055589

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:28892042, PubMed:25278503, PubMed:11551941). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins (PubMed:11551941, PubMed:25278503).

Interacts with OXA1L.

By similarity1 Publication3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115824, 85 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q13084

Database of interacting proteins

More...
DIPi
DIP-61135N

Protein interaction database and analysis system

More...
IntActi
Q13084, 82 interactors

Molecular INTeraction database

More...
MINTi
Q13084

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000199706

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1256
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q13084

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3279 Eukaryota
ENOG410XQHX LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017359

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q13084

KEGG Orthology (KO)

More...
KOi
K02902

Identification of Orthologs from Complete Genome Data

More...
OMAi
MSVVVTE

Database of Orthologous Groups

More...
OrthoDBi
1558223at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q13084

TreeFam database of animal gene trees

More...
TreeFami
TF313040

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.170.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034704 L28p-like
IPR026569 Ribo_L28/L24
IPR037147 Ribo_L28/L24_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13528 PTHR13528, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00830 Ribosomal_L28, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF143800 SSF143800, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q13084-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLHKYPVWL WKRLQLREGI CSRLPGHYLR SLEEERTPTP VHYRPHGAKF
60 70 80 90 100
KINPKNGQRE RVEDVPIPIY FPPESQRGLW GGEGWILGQI YANNDKLSKR
110 120 130 140 150
LKKVWKPQLF EREFYSEILD KKFTVTVTMR TLDLIDEAYG LDFYILKTPK
160 170 180 190 200
EDLCSKFGMD LKRGMLLRLA RQDPQLHPED PERRAAIYDK YKEFAIPEEE
210 220 230 240 250
AEWVGLTLEE AIEKQRLLEE KDPVPLFKIY VAELIQQLQQ QALSEPAVVQ

KRASGQ
Length:256
Mass (Da):30,157
Last modified:January 24, 2006 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6578FD1E98FC5A6E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2IDC5A2IDC5_HUMAN
39S ribosomal protein L28, mitochon...
MRPL28
48Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2IDC6A2IDC6_HUMAN
39S ribosomal protein L28, mitochon...
MRPL28
240Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2IDC7A2IDC7_HUMAN
39S ribosomal protein L28, mitochon...
MRPL28
194Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q4TT37Q4TT37_HUMAN
39S ribosomal protein L28, mitochon...
MRPL28
218Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC50181 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAK61226 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti147K → KASG in AAK61226 (PubMed:11157797).Curated1
Sequence conflicti148 – 150TPK → ASG (PubMed:15616553).Curated3
Sequence conflicti252R → T in AAC50181 (PubMed:7751637).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05421927H → Y2 PublicationsCorresponds to variant dbSNP:rs3194151Ensembl.1
Natural variantiVAR_052024160D → E1 PublicationCorresponds to variant dbSNP:rs11557302Ensembl.1
Natural variantiVAR_061806230Y → C. Corresponds to variant dbSNP:rs13226Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK315180 mRNA Translation: BAG37621.1
AE006463 Genomic DNA Translation: AAK61226.1 Sequence problems.
Z97634 Genomic DNA No translation available.
CH471112 Genomic DNA Translation: EAW85827.1
CH471112 Genomic DNA Translation: EAW85829.1
CH471112 Genomic DNA Translation: EAW85832.1
CH471112 Genomic DNA Translation: EAW85834.1
BC000507 mRNA Translation: AAH00507.2
BC000990 mRNA Translation: AAH00990.2
U19796 mRNA Translation: AAC50181.1 Different initiation.
BT009857 mRNA Translation: AAP88859.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32349.1

NCBI Reference Sequences

More...
RefSeqi
NP_006419.2, NM_006428.4
XP_005255098.1, XM_005255041.1
XP_011520653.1, XM_011522351.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000199706; ENSP00000199706; ENSG00000086504
ENST00000389675; ENSP00000374326; ENSG00000086504
ENST00000648346; ENSP00000497004; ENSG00000086504

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10573

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10573

UCSC genome browser

More...
UCSCi
uc002cgs.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315180 mRNA Translation: BAG37621.1
AE006463 Genomic DNA Translation: AAK61226.1 Sequence problems.
Z97634 Genomic DNA No translation available.
CH471112 Genomic DNA Translation: EAW85827.1
CH471112 Genomic DNA Translation: EAW85829.1
CH471112 Genomic DNA Translation: EAW85832.1
CH471112 Genomic DNA Translation: EAW85834.1
BC000507 mRNA Translation: AAH00507.2
BC000990 mRNA Translation: AAH00990.2
U19796 mRNA Translation: AAC50181.1 Different initiation.
BT009857 mRNA Translation: AAP88859.1
CCDSiCCDS32349.1
RefSeqiNP_006419.2, NM_006428.4
XP_005255098.1, XM_005255041.1
XP_011520653.1, XM_011522351.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J7Yelectron microscopy3.40X1-256[»]
5OOLelectron microscopy3.06X1-256[»]
5OOMelectron microscopy3.03X1-256[»]
6NU2electron microscopy3.90X2-244[»]
6NU3electron microscopy4.40X2-244[»]
SMRiQ13084
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi115824, 85 interactors
CORUMiQ13084
DIPiDIP-61135N
IntActiQ13084, 82 interactors
MINTiQ13084
STRINGi9606.ENSP00000199706

PTM databases

iPTMnetiQ13084
PhosphoSitePlusiQ13084
SwissPalmiQ13084

Polymorphism and mutation databases

BioMutaiMRPL28
DMDMi85695426

Proteomic databases

EPDiQ13084
jPOSTiQ13084
MassIVEiQ13084
MaxQBiQ13084
PaxDbiQ13084
PeptideAtlasiQ13084
PRIDEiQ13084
ProteomicsDBi59138

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
10573

Genome annotation databases

EnsembliENST00000199706; ENSP00000199706; ENSG00000086504
ENST00000389675; ENSP00000374326; ENSG00000086504
ENST00000648346; ENSP00000497004; ENSG00000086504
GeneIDi10573
KEGGihsa:10573
UCSCiuc002cgs.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10573
DisGeNETi10573

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MRPL28
HGNCiHGNC:14484 MRPL28
HPAiCAB033542
HPA030594
HPA055589
MIMi604853 gene
neXtProtiNX_Q13084
PharmGKBiPA30515

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3279 Eukaryota
ENOG410XQHX LUCA
GeneTreeiENSGT00390000017359
InParanoidiQ13084
KOiK02902
OMAiMSVVVTE
OrthoDBi1558223at2759
PhylomeDBiQ13084
TreeFamiTF313040

Enzyme and pathway databases

ReactomeiR-HSA-5368286 Mitochondrial translation initiation
R-HSA-5389840 Mitochondrial translation elongation
R-HSA-5419276 Mitochondrial translation termination

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
MRPL28 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
MRPL28

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
10573
PharosiQ13084

Protein Ontology

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PROi
PR:Q13084

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000086504 Expressed in 220 organ(s), highest expression level in apex of heart
ExpressionAtlasiQ13084 baseline and differential
GenevisibleiQ13084 HS

Family and domain databases

Gene3Di2.30.170.40, 1 hit
InterProiView protein in InterPro
IPR034704 L28p-like
IPR026569 Ribo_L28/L24
IPR037147 Ribo_L28/L24_sf
PANTHERiPTHR13528 PTHR13528, 1 hit
PfamiView protein in Pfam
PF00830 Ribosomal_L28, 1 hit
SUPFAMiSSF143800 SSF143800, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRM28_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q13084
Secondary accession number(s): B2RCM4
, D3DU46, Q4TT39, Q96S26, Q9BQD8, Q9BR04
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 24, 2006
Last modified: September 18, 2019
This is version 161 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  7. Ribosomal proteins
    Ribosomal proteins families and list of entries
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