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Protein

Pyruvoyl-dependent arginine decarboxylase

Gene

pdaD

Organism
Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-arginine = agmatine + CO2.UniRule annotation

Cofactori

pyruvateUniRule annotationNote: Binds 1 pyruvoyl group covalently per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylase, Lyase
LigandPyruvate

Enzyme and pathway databases

BioCyciMBUR259564:G1G6A-1959-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvoyl-dependent arginine decarboxylaseUniRule annotation (EC:4.1.1.19UniRule annotation)
Short name:
PvlArgDCUniRule annotation
Cleaved into the following 2 chains:
Pyruvoyl-dependent arginine decarboxylase subunit betaUniRule annotation
Pyruvoyl-dependent arginine decarboxylase subunit alphaUniRule annotation
Gene namesi
Name:pdaDUniRule annotation
Ordered Locus Names:Mbur_1870
OrganismiMethanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
Taxonomic identifieri259564 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanococcoides
Proteomesi
  • UP000001979 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000683931 – 40Pyruvoyl-dependent arginine decarboxylase subunit betaUniRule annotationAdd BLAST40
ChainiPRO_100006839441 – 180Pyruvoyl-dependent arginine decarboxylase subunit alphaUniRule annotationAdd BLAST140

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei41Pyruvic acid (Ser)UniRule annotation1

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei40 – 41Cleavage (non-hydrolytic)UniRule annotation2

Interactioni

Protein-protein interaction databases

STRINGi259564.Mbur_1870

Structurei

3D structure databases

ProteinModelPortaliQ12UX3
SMRiQ12UX3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PdaD family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04490 Archaea
COG1945 LUCA
HOGENOMiHOG000012204
KOiK02626
OMAiSEHHSFG
OrthoDBiPOG093Z0D0B

Family and domain databases

Gene3Di3.50.20.10, 1 hit
HAMAPiMF_01404 PvlArgDC, 1 hit
InterProiView protein in InterPro
IPR016104 Pyr-dep_his/arg-deCO2ase
IPR016105 Pyr-dep_his/arg-deCO2ase_sand
IPR002724 Pyruvoyl-dep_arg_deCO2ase
PANTHERiPTHR40438 PTHR40438, 1 hit
PfamiView protein in Pfam
PF01862 PvlArgDC, 1 hit
PIRSFiPIRSF005216 Pyruvoyl-dep_arg_deCO2ase, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD010449 Pyruvoyl-dep_arg_deCO2ase, 1 hit
SFLDiSFLDG01170 Pyruvoyl-dependent_arginine_de, 1 hit
SUPFAMiSSF56271 SSF56271, 1 hit
TIGRFAMsiTIGR00286 TIGR00286, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12UX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPKKAFVVK GTGVHKDKLA SFELALRDAG IEKFNLVTVS SILPPNCSIV
60 70 80 90 100
SRKEGLEELA PGQIVYCVMA KNQTNEPERM IAAAIGNAVP VDSNDYGYIS
110 120 130 140 150
EHHSFGEDER TAGIYAEDLA ATMLATTLGI EFDADSAWGE RERVYKASGH
160 170 180
IFDTVHYCRC VKGDENGLWT TVVVSMVFVL
Length:180
Mass (Da):19,688
Last modified:August 22, 2006 - v1
Checksum:iAD44697D865CD971
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000300 Genomic DNA Translation: ABE52753.1
RefSeqiWP_011499896.1, NC_007955.1

Genome annotation databases

EnsemblBacteriaiABE52753; ABE52753; Mbur_1870
GeneIDi3997531
KEGGimbu:Mbur_1870

Similar proteinsi

Entry informationi

Entry nameiPDAD_METBU
AccessioniPrimary (citable) accession number: Q12UX3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 22, 2006
Last modified: February 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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