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UniProtKB - Q12GE3 (Q12GE3_POLSJ)
Protein
Submitted name:
Galactarate dehydratase / L-talarate dehydratase
Gene
Bpro_0435
Organism
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 211 | Magnesium 1Combined sources | 1 | |
Metal bindingi | 237 | Magnesium 1Combined sources | 1 | |
Metal bindingi | 252 | Calcium; via carbonyl oxygenCombined sources | 1 | |
Metal bindingi | 252 | Magnesium 2; via carbonyl oxygenCombined sources | 1 | |
Metal bindingi | 255 | Calcium; via carbonyl oxygenCombined sources | 1 | |
Metal bindingi | 255 | Magnesium 2; via carbonyl oxygenCombined sources | 1 | |
Metal bindingi | 263 | Magnesium 1Combined sources | 1 |
GO - Molecular functioni
- galactarate dehydratase activity Source: UniProtKB-EC
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- cellular amino acid catabolic process Source: InterPro
Keywordsi
Molecular function | LyaseImported |
Ligand | CalciumCombined sources, MagnesiumCombined sources, Metal-bindingCombined sources |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:Bpro_0435Imported |
Organismi | Polaromonas sp. (strain JS666 / ATCC BAA-500)Imported |
Taxonomic identifieri | 296591 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas › unclassified Polaromonas |
Proteomesi |
|
Structurei
3D structure databases
SMRi | Q12GE3 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q12GE3 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 162 – 258 | MR_MLEInterPro annotationAdd BLAST | 97 |
Phylogenomic databases
eggNOGi | COG4948, Bacteria |
HOGENOMi | CLU_030273_3_1_4 |
OMAi | CEAYYIP |
OrthoDBi | 743369at2 |
Family and domain databases
Gene3Di | 3.20.20.120, 1 hit 3.30.390.10, 1 hit |
InterProi | View protein in InterPro IPR036849, Enolase-like_C_sf IPR029017, Enolase-like_N IPR029065, Enolase_C-like IPR033978, L-talarate_dehydratase IPR018110, Mandel_Rmase/mucon_lact_enz_CS IPR013342, Mandelate_racemase_C IPR013341, Mandelate_racemase_N_dom |
Pfami | View protein in Pfam PF13378, MR_MLE_C, 1 hit PF02746, MR_MLE_N, 1 hit |
SFLDi | SFLDF00134, L-talarate/galactarate_dehydra, 1 hit |
SMARTi | View protein in SMART SM00922, MR_MLE, 1 hit |
SUPFAMi | SSF51604, SSF51604, 1 hit SSF54826, SSF54826, 1 hit |
PROSITEi | View protein in PROSITE PS00909, MR_MLE_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q12GE3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKTTTSSTPS DRITWVRISS CYLPLATPIS DAKVLTGRQK PMTEIAILFA
60 70 80 90 100
EIETAGGHQG LGFSYSKRAG GPGQFAHARE IAPALIGEDP SDIAKLWDKL
110 120 130 140 150
CWAGASAGRS GLSTQAIGAF DVALWDLKAK RAGLSLAKLL GSYRDSVRCY
160 170 180 190 200
NTSGGFLHTP IDQLMVNASA SIERGIGGIK LKVGQPDGAL DIARVTAVRK
210 220 230 240 250
HLGDAVPLMV DANQQWDRPT AQRMCRIFEP FNLVWIEEPL DAYDHEGHAA
260 270 280 290 300
LALQFDTPIA TGEMLTSAAE HGDLIRHRAA DYLMPDAPRV GGITPFLKIA
310 320 330 340 350
SLAEHAGLML APHFAMELHV HLAAAYPREP WVEHFEWLEP LFNERIEIRD
360 370 380
GRMLVPTRPG LGLTLSGQVK AWTREEAQVG TRP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000316 Genomic DNA Translation: ABE42399.1 |
RefSeqi | WP_011481406.1, NC_007948.1 |
Genome annotation databases
EnsemblBacteriai | ABE42399; ABE42399; Bpro_0435 |
KEGGi | pol:Bpro_0435 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000316 Genomic DNA Translation: ABE42399.1 |
RefSeqi | WP_011481406.1, NC_007948.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2OG9 | X-ray | 1.90 | A/B | 2-383 | [»] | |
3CB3 | X-ray | 2.00 | A/B/C/D | 2-383 | [»] | |
SMRi | Q12GE3 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 296591.Bpro_0435 |
Genome annotation databases
EnsemblBacteriai | ABE42399; ABE42399; Bpro_0435 |
KEGGi | pol:Bpro_0435 |
Phylogenomic databases
eggNOGi | COG4948, Bacteria |
HOGENOMi | CLU_030273_3_1_4 |
OMAi | CEAYYIP |
OrthoDBi | 743369at2 |
Miscellaneous databases
EvolutionaryTracei | Q12GE3 |
Family and domain databases
Gene3Di | 3.20.20.120, 1 hit 3.30.390.10, 1 hit |
InterProi | View protein in InterPro IPR036849, Enolase-like_C_sf IPR029017, Enolase-like_N IPR029065, Enolase_C-like IPR033978, L-talarate_dehydratase IPR018110, Mandel_Rmase/mucon_lact_enz_CS IPR013342, Mandelate_racemase_C IPR013341, Mandelate_racemase_N_dom |
Pfami | View protein in Pfam PF13378, MR_MLE_C, 1 hit PF02746, MR_MLE_N, 1 hit |
SFLDi | SFLDF00134, L-talarate/galactarate_dehydra, 1 hit |
SMARTi | View protein in SMART SM00922, MR_MLE, 1 hit |
SUPFAMi | SSF51604, SSF51604, 1 hit SSF54826, SSF54826, 1 hit |
PROSITEi | View protein in PROSITE PS00909, MR_MLE_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q12GE3_POLSJ | |
Accessioni | Q12GE3Primary (citable) accession number: Q12GE3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 22, 2006 |
Last sequence update: | August 22, 2006 | |
Last modified: | September 29, 2021 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |