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Entry version 166 (16 Oct 2019)
Sequence version 2 (18 Apr 2006)
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Protein

ELAV-like protein 2

Gene

ELAVL2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs (By similarity). Seems to recognize a GAAA motif (By similarity). Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-72163 mRNA Splicing - Major Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ELAV-like protein 2
Alternative name(s):
ELAV-like neuronal protein 1
Hu-antigen B
Short name:
HuB
Nervous system-specific RNA-binding protein Hel-N1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ELAVL2
Synonyms:HUB
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:3313 ELAVL2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
601673 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q12926

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
1993

Open Targets

More...
OpenTargetsi
ENSG00000107105

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA27741

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q12926

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ELAVL2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
93141258

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000815791 – 359ELAV-like protein 2Add BLAST359

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei221PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q12926

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q12926

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q12926

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q12926

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q12926

PeptideAtlas

More...
PeptideAtlasi
Q12926

PRoteomics IDEntifications database

More...
PRIDEi
Q12926

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
59031 [Q12926-1]
59032 [Q12926-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q12926

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q12926

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q12926

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Brain; neural-specific.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000107105 Expressed in 132 organ(s), highest expression level in Brodmann (1909) area 23

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q12926 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q12926 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB022222

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with IGF2BP1 (PubMed:17289661).

Interacts with MAP1B light chain LC1 (By similarity).

By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
108308, 131 interactors

Protein interaction database and analysis system

More...
IntActi
Q12926, 105 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000380479

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q12926

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 117RRM 1PROSITE-ProRule annotationAdd BLAST79
Domaini125 – 205RRM 2PROSITE-ProRule annotationAdd BLAST81
Domaini276 – 354RRM 3PROSITE-ProRule annotationAdd BLAST79

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RRM elav family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0145 Eukaryota
ENOG410XP7S LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156823

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231162

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q12926

KEGG Orthology (KO)

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KOi
K13208

Database of Orthologous Groups

More...
OrthoDBi
775799at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q12926

TreeFam database of animal gene trees

More...
TreeFami
TF313377

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12650 RRM1_Hu, 1 hit
cd12775 RRM2_HuB, 1 hit
cd12654 RRM3_HuB, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006548 ELAD_HU_SF
IPR034775 ELAV/Hu_RRM1
IPR034999 HuB_RRM2
IPR034914 HuB_RRM3
IPR002343 Hud_Sxl_RNA
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076 RRM_1, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00961 HUDSXLRNA

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360 RRM, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01661 ELAV_HUD_SF, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q12926-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
METQLSNGPT CNNTANGPTT INNNCSSPVD SGNTEDSKTN LIVNYLPQNM
60 70 80 90 100
TQEELKSLFG SIGEIESCKL VRDKITGQSL GYGFVNYIDP KDAEKAINTL
110 120 130 140 150
NGLRLQTKTI KVSYARPSSA SIRDANLYVS GLPKTMTQKE LEQLFSQYGR
160 170 180 190 200
IITSRILVDQ VTGISRGVGF IRFDKRIEAE EAIKGLNGQK PPGATEPITV
210 220 230 240 250
KFANNPSQKT NQAILSQLYQ SPNRRYPGPL AQQAQRFRLD NLLNMAYGVK
260 270 280 290 300
RFSPMTIDGM TSLAGINIPG HPGTGWCIFV YNLAPDADES ILWQMFGPFG
310 320 330 340 350
AVTNVKVIRD FNTNKCKGFG FVTMTNYDEA AMAIASLNGY RLGDRVLQVS

FKTNKTHKA
Length:359
Mass (Da):39,504
Last modified:April 18, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i15E87088FC546DDC
GO
Isoform 2 (identifier: Q12926-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     239-251: Missing.

Show »
Length:346
Mass (Da):38,015
Checksum:iF1EC0F69EE5D15DD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AM48B1AM48_HUMAN
ELAV-like protein
ELAVL2
189Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MRX1A0A0A0MRX1_HUMAN
ELAV-like protein
ELAVL2
389Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JB16C9JB16_HUMAN
ELAV-like protein 2
ELAVL2
90Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD92531 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti335A → R (PubMed:8158249).Curated1
Sequence conflicti335A → R (PubMed:7972035).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_005788239 – 251Missing in isoform 2. 2 PublicationsAdd BLAST13

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U12431 mRNA Translation: AAA69698.1
U29943 mRNA Translation: AAA70417.1
AB209294 mRNA Translation: BAD92531.1 Different initiation.
AL161628 Genomic DNA No translation available.
AL445623 Genomic DNA No translation available.
CH471071 Genomic DNA Translation: EAW58581.1
CH471071 Genomic DNA Translation: EAW58582.1
BC030692 mRNA Translation: AAH30692.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS55298.1 [Q12926-2]
CCDS6515.1 [Q12926-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
I38726
I39077

NCBI Reference Sequences

More...
RefSeqi
NP_001164666.1, NM_001171195.1 [Q12926-2]
NP_001164668.1, NM_001171197.1 [Q12926-2]
NP_004423.2, NM_004432.3 [Q12926-1]
XP_016869908.1, XM_017014419.1
XP_016869909.1, XM_017014420.1
XP_016869910.1, XM_017014421.1
XP_016869911.1, XM_017014422.1
XP_016869912.1, XM_017014423.1
XP_016869913.1, XM_017014424.1
XP_016869914.1, XM_017014425.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000223951; ENSP00000223951; ENSG00000107105 [Q12926-2]
ENST00000380117; ENSP00000369460; ENSG00000107105 [Q12926-1]
ENST00000397312; ENSP00000380479; ENSG00000107105 [Q12926-1]
ENST00000544538; ENSP00000440998; ENSG00000107105 [Q12926-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1993

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:1993

UCSC genome browser

More...
UCSCi
uc003zps.4 human [Q12926-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12431 mRNA Translation: AAA69698.1
U29943 mRNA Translation: AAA70417.1
AB209294 mRNA Translation: BAD92531.1 Different initiation.
AL161628 Genomic DNA No translation available.
AL445623 Genomic DNA No translation available.
CH471071 Genomic DNA Translation: EAW58581.1
CH471071 Genomic DNA Translation: EAW58582.1
BC030692 mRNA Translation: AAH30692.1
CCDSiCCDS55298.1 [Q12926-2]
CCDS6515.1 [Q12926-1]
PIRiI38726
I39077
RefSeqiNP_001164666.1, NM_001171195.1 [Q12926-2]
NP_001164668.1, NM_001171197.1 [Q12926-2]
NP_004423.2, NM_004432.3 [Q12926-1]
XP_016869908.1, XM_017014419.1
XP_016869909.1, XM_017014420.1
XP_016869910.1, XM_017014421.1
XP_016869911.1, XM_017014422.1
XP_016869912.1, XM_017014423.1
XP_016869913.1, XM_017014424.1
XP_016869914.1, XM_017014425.1

3D structure databases

SMRiQ12926
ModBaseiSearch...

Protein-protein interaction databases

BioGridi108308, 131 interactors
IntActiQ12926, 105 interactors
STRINGi9606.ENSP00000380479

PTM databases

iPTMnetiQ12926
PhosphoSitePlusiQ12926
SwissPalmiQ12926

Polymorphism and mutation databases

BioMutaiELAVL2
DMDMi93141258

Proteomic databases

EPDiQ12926
jPOSTiQ12926
MassIVEiQ12926
MaxQBiQ12926
PaxDbiQ12926
PeptideAtlasiQ12926
PRIDEiQ12926
ProteomicsDBi59031 [Q12926-1]
59032 [Q12926-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
1993

Genome annotation databases

EnsembliENST00000223951; ENSP00000223951; ENSG00000107105 [Q12926-2]
ENST00000380117; ENSP00000369460; ENSG00000107105 [Q12926-1]
ENST00000397312; ENSP00000380479; ENSG00000107105 [Q12926-1]
ENST00000544538; ENSP00000440998; ENSG00000107105 [Q12926-1]
GeneIDi1993
KEGGihsa:1993
UCSCiuc003zps.4 human [Q12926-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
1993
DisGeNETi1993

GeneCards: human genes, protein and diseases

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GeneCardsi
ELAVL2
HGNCiHGNC:3313 ELAVL2
HPAiCAB022222
MIMi601673 gene
neXtProtiNX_Q12926
OpenTargetsiENSG00000107105
PharmGKBiPA27741

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG0145 Eukaryota
ENOG410XP7S LUCA
GeneTreeiENSGT00940000156823
HOGENOMiHOG000231162
InParanoidiQ12926
KOiK13208
OrthoDBi775799at2759
PhylomeDBiQ12926
TreeFamiTF313377

Enzyme and pathway databases

ReactomeiR-HSA-72163 mRNA Splicing - Major Pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ELAVL2 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ELAVL2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
1993
PharosiQ12926

Protein Ontology

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PROi
PR:Q12926

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000107105 Expressed in 132 organ(s), highest expression level in Brodmann (1909) area 23
ExpressionAtlasiQ12926 baseline and differential
GenevisibleiQ12926 HS

Family and domain databases

CDDicd12650 RRM1_Hu, 1 hit
cd12775 RRM2_HuB, 1 hit
cd12654 RRM3_HuB, 1 hit
Gene3Di3.30.70.330, 3 hits
InterProiView protein in InterPro
IPR006548 ELAD_HU_SF
IPR034775 ELAV/Hu_RRM1
IPR034999 HuB_RRM2
IPR034914 HuB_RRM3
IPR002343 Hud_Sxl_RNA
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 3 hits
PRINTSiPR00961 HUDSXLRNA
SMARTiView protein in SMART
SM00360 RRM, 3 hits
SUPFAMiSSF54928 SSF54928, 2 hits
TIGRFAMsiTIGR01661 ELAV_HUD_SF, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiELAV2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q12926
Secondary accession number(s): D3DRK3
, Q13235, Q59G15, Q8NEM4, Q9H1Q8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: April 18, 2006
Last modified: October 16, 2019
This is version 166 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
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