UniProtKB - Q12834 (CDC20_HUMAN)
Cell division cycle protein 20 homolog
CDC20
Functioni
: protein ubiquitination Pathwayi
This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.
GO - Molecular functioni
- anaphase-promoting complex binding Source: GO_Central
- enzyme binding Source: UniProtKB
- histone deacetylase binding Source: Ensembl
- protein C-terminus binding Source: UniProtKB
- ubiquitin ligase activator activity Source: GO_Central
GO - Biological processi
- anaphase-promoting complex-dependent catabolic process Source: UniProtKB
- cell differentiation Source: UniProtKB-KW
- cell division Source: UniProtKB-KW
- mitotic sister chromatid cohesion Source: Ensembl
- mitotic spindle assembly Source: Ensembl
- mitotic spindle assembly checkpoint Source: Reactome
- nervous system development Source: UniProtKB-KW
- positive regulation of anaphase-promoting complex-dependent catabolic process Source: GO_Central
- positive regulation of cell population proliferation Source: Ensembl
- positive regulation of synapse maturation Source: UniProtKB
- positive regulation of synaptic plasticity Source: UniProtKB
- positive regulation of ubiquitin protein ligase activity Source: UniProtKB
- protein deubiquitination Source: Reactome
- protein ubiquitination Source: UniProtKB-UniPathway
- regulation of dendrite development Source: Ensembl
- regulation of meiotic nuclear division Source: Ensembl
- regulation of mitotic cell cycle phase transition Source: Reactome
- ubiquitin-dependent protein catabolic process Source: Reactome
Keywordsi
Biological process | Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway |
Enzyme and pathway databases
PathwayCommonsi | Q12834 |
Reactomei | R-HSA-141405, Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141430, Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-174048, APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174113, SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174154, APC/C:Cdc20 mediated degradation of Securin R-HSA-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-176407, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176408, Regulation of APC/C activators between G1/S and early anaphase R-HSA-176409, APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176417, Phosphorylation of Emi1 R-HSA-179409, APC-Cdc20 mediated degradation of Nek2A R-HSA-2467813, Separation of Sister Chromatids R-HSA-2500257, Resolution of Sister Chromatid Cohesion R-HSA-5663220, RHO GTPases Activate Formins R-HSA-5689880, Ub-specific processing proteases R-HSA-68877, Mitotic Prometaphase R-HSA-9648025, EML4 and NUDC in mitotic spindle formation R-HSA-983168, Antigen processing: Ubiquitination & Proteasome degradation |
SignaLinki | Q12834 |
SIGNORi | Q12834 |
UniPathwayi | UPA00143 |
Protein family/group databases
TCDBi | 9.A.61.2.2, the domain of unknown function 3339 (duf3339) family |
Names & Taxonomyi
Protein namesi | Recommended name: Cell division cycle protein 20 homologAlternative name(s): p55CDC |
Gene namesi | Name:CDC20 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:1723, CDC20 |
MIMi | 603618, gene |
neXtProti | NX_Q12834 |
VEuPathDBi | HostDB:ENSG00000117399.13 |
Subcellular locationi
Cytoskeleton
- centrosome 1 Publication
- spindle pole 1 Publication
Cytoskeleton
- centrosome Source: Ensembl
- spindle Source: ProtInc
- spindle pole Source: UniProtKB-SubCell
Cytosol
- cytosol Source: HPA
Nucleus
- nucleoplasm Source: HPA
Other locations
- perinuclear region of cytoplasm Source: Ensembl
- protein-containing complex Source: Ensembl
Keywords - Cellular componenti
Cytoplasm, CytoskeletonPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 41 | S → A: Loss of BUB1-mediated phosphorylation and inhibition and partially defective spindle-assembly checkpoint; when associated with A-72; A-92; A-153; A-157 and A-161. 1 Publication | 1 | |
Mutagenesisi | 72 | S → A: Loss of BUB1-mediated phosphorylation and inhibition and partially defective spindle-assembly checkpoint; when associated with A-41; A-92; A-153; A-157 and A-161. 1 Publication | 1 | |
Mutagenesisi | 92 | S → A: Loss of BUB1-mediated phosphorylation and inhibition and partially defective spindle-assembly checkpoint; when associated with A-41; A-72; A-153; A-157 and A-161. 1 Publication | 1 | |
Mutagenesisi | 132 | R → A: Loss of interaction with MAD2L1. 1 Publication | 1 | |
Mutagenesisi | 153 | S → A: Loss of BUB1-mediated phosphorylation and inhibition and partially defective spindle-assembly checkpoint; when associated with A-42; A-72; A-92; A-157 and A-161. 1 Publication | 1 | |
Mutagenesisi | 157 | T → A: Loss of BUB1-mediated phosphorylation and inhibition and partially defective spindle-assembly checkpoint; when associated with A-42; A-72; A-92; A-153 and A-161. 1 Publication | 1 | |
Mutagenesisi | 161 | S → A: Loss of BUB1-mediated phosphorylation and inhibition and partially defective spindle-assembly checkpoint; when associated with A-72; A-92; A-153; A-157 and A-161. 1 Publication | 1 | |
Mutagenesisi | 485 | K → R: Does not affect its ability to bind the APC/C complex; when associated with R-490. 1 Publication | 1 | |
Mutagenesisi | 490 | K → R: Does not affect its ability to bind the APC/C complex; when associated with R-485. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 991 |
OpenTargetsi | ENSG00000117399 |
PharmGKBi | PA26257 |
Miscellaneous databases
Pharosi | Q12834, Tbio |
Genetic variation databases
BioMutai | CDC20 |
DMDMi | 37537762 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050900 | 1 – 499 | Cell division cycle protein 20 homologAdd BLAST | 499 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 41 | PhosphoserineCombined sources1 Publication | 1 | |
Modified residuei | 66 | N6-acetyllysine1 Publication | 1 | |
Modified residuei | 70 | PhosphothreonineCombined sources1 Publication | 1 | |
Modified residuei | 72 | Phosphoserine1 Publication | 1 | |
Modified residuei | 92 | Phosphoserine1 Publication | 1 | |
Modified residuei | 106 | Phosphothreonine1 Publication | 1 | |
Modified residuei | 153 | Phosphoserine1 Publication | 1 | |
Modified residuei | 157 | Phosphothreonine1 Publication | 1 | |
Modified residuei | 161 | Phosphoserine1 Publication | 1 | |
Cross-linki | 485 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication | ||
Cross-linki | 490 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication |
Post-translational modificationi
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q12834 |
jPOSTi | Q12834 |
MassIVEi | Q12834 |
MaxQBi | Q12834 |
PaxDbi | Q12834 |
PeptideAtlasi | Q12834 |
PRIDEi | Q12834 |
ProteomicsDBi | 58976 |
PTM databases
iPTMneti | Q12834 |
PhosphoSitePlusi | Q12834 |
SwissPalmi | Q12834 |
Expressioni
Developmental stagei
Gene expression databases
Bgeei | ENSG00000117399, Expressed in ventricular zone and 167 other tissues |
Genevisiblei | Q12834, HS |
Organism-specific databases
HPAi | ENSG00000117399, Tissue enhanced (lymphoid tissue, testis) |
Interactioni
Subunit structurei
Component of a complex with CDC20, CDC27, SPATC1 and TUBG1 (By similarity).
Interacts with NEUROD2 (By similarity).
Interacts with dimeric MAD2L1 in its closed conformation form (PubMed:9811605, PubMed:9637688, PubMed:15525512, PubMed:19098431, PubMed:29162720).
Interacts with BUB1B (PubMed:15525512, PubMed:18997788, PubMed:19098431). The phosphorylated form interacts with APC/C (PubMed:9811605, PubMed:9734353, PubMed:9637688).
Interacts with NINL (PubMed:17403670). May interact with MAD2L2 (PubMed:11459826).
Interacts with CDK5RAP2 (PubMed:19282672).
Interacts with SIRT2 (PubMed:22014574).
Interacts with isoform 1 of NEK2 (PubMed:20034488).
Interacts with HSF1 (via phosphorylated form); this interaction occurs in mitosis in a MAD2L1-dependent manner and prevents PLK1-stimulated degradation of HSF1 by blocking the recruitment of the SCF(BTRC) ubiquitin ligase complex (PubMed:18794143).
Interacts (via the N-terminal substrate-binding domain) with FBXO5 (By similarity).
By similarity13 PublicationsBinary interactionsi
Hide detailsQ12834
GO - Molecular functioni
- enzyme binding Source: UniProtKB
- histone deacetylase binding Source: Ensembl
- protein C-terminus binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 107427, 196 interactors |
ComplexPortali | CPX-3946, Mitotic Checkpoint Complex CPX-6087, Anaphase-Promoting complex, CDC20 variant |
CORUMi | Q12834 |
DIPi | DIP-29655N |
ELMi | Q12834 |
IntActi | Q12834, 72 interactors |
MINTi | Q12834 |
STRINGi | 9606.ENSP00000361540 |
Miscellaneous databases
RNActi | Q12834, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q12834 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 182 – 221 | WD 1Add BLAST | 40 | |
Repeati | 224 – 263 | WD 2Add BLAST | 40 | |
Repeati | 266 – 303 | WD 3Add BLAST | 38 | |
Repeati | 307 – 346 | WD 4Add BLAST | 40 | |
Repeati | 353 – 395 | WD 5Add BLAST | 43 | |
Repeati | 397 – 438 | WD 6Add BLAST | 42 | |
Repeati | 441 – 480 | WD 7Add BLAST | 40 |
Sequence similaritiesi
Keywords - Domaini
Repeat, WD repeatPhylogenomic databases
eggNOGi | KOG0305, Eukaryota |
GeneTreei | ENSGT00950000183104 |
HOGENOMi | CLU_014831_6_1_1 |
InParanoidi | Q12834 |
OMAi | WSPHKKE |
OrthoDBi | 1220675at2759 |
PhylomeDBi | Q12834 |
TreeFami | TF101065 |
Family and domain databases
DisProti | DP01118 |
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR024977, Apc4_WD40_dom IPR033010, Cdc20/Fizzy IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
PANTHERi | PTHR19918, PTHR19918, 1 hit |
Pfami | View protein in Pfam PF12894, ANAPC4_WD40, 1 hit PF00400, WD40, 4 hits |
SMARTi | View protein in SMART SM00320, WD40, 7 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 1 hit PS50082, WD_REPEATS_2, 3 hits PS50294, WD_REPEATS_REGION, 1 hit |
i Sequence
Sequence statusi: Complete.
10 20 30 40 50
MAQFAFESDL HSLLQLDAPI PNAPPARWQR KAKEAAGPAP SPMRAANRSH
60 70 80 90 100
SAGRTPGRTP GKSSSKVQTT PSKPGGDRYI PHRSAAQMEV ASFLLSKENQ
110 120 130 140 150
PENSQTPTKK EHQKAWALNL NGFDVEEAKI LRLSGKPQNA PEGYQNRLKV
160 170 180 190 200
LYSQKATPGS SRKTCRYIPS LPDRILDAPE IRNDYYLNLV DWSSGNVLAV
210 220 230 240 250
ALDNSVYLWS ASSGDILQLL QMEQPGEYIS SVAWIKEGNY LAVGTSSAEV
260 270 280 290 300
QLWDVQQQKR LRNMTSHSAR VGSLSWNSYI LSSGSRSGHI HHHDVRVAEH
310 320 330 340 350
HVATLSGHSQ EVCGLRWAPD GRHLASGGND NLVNVWPSAP GEGGWVPLQT
360 370 380 390 400
FTQHQGAVKA VAWCPWQSNV LATGGGTSDR HIRIWNVCSG ACLSAVDAHS
410 420 430 440 450
QVCSILWSPH YKELISGHGF AQNQLVIWKY PTMAKVAELK GHTSRVLSLT
460 470 480 490
MSPDGATVAS AAADETLRLW RCFELDPARR REREKASAAK SSLIHQGIR
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 101 | P → S in AAA19017 (PubMed:7513050).Curated | 1 | |
Sequence conflicti | 117 | A → V in AAH00624 (PubMed:15489334).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_030368 | 402 | V → M1 PublicationCorresponds to variant dbSNP:rs45443196Ensembl. | 1 | |
Natural variantiVAR_030369 | 479 | R → Q1 PublicationCorresponds to variant dbSNP:rs45461499Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U05340 mRNA Translation: AAA19017.1 AF099644 mRNA Translation: AAD16405.1 AK312780 mRNA Translation: BAG35643.1 BT007388 mRNA Translation: AAP36052.1 DQ473545 Genomic DNA Translation: ABE96834.1 AL139289 Genomic DNA No translation available. CH471059 Genomic DNA Translation: EAX07101.1 CH471059 Genomic DNA Translation: EAX07102.1 BC000624 mRNA Translation: AAH00624.1 BC001088 mRNA Translation: AAH01088.1 BC006272 mRNA Translation: AAH06272.1 BC009425 mRNA Translation: AAH09425.1 BC009426 mRNA Translation: AAH09426.1 BC010044 mRNA Translation: AAH10044.1 BC012803 mRNA Translation: AAH12803.1 BC012827 mRNA Translation: AAH12827.1 BC013303 mRNA Translation: AAH13303.1 BC015998 mRNA Translation: AAH15998.1 BC024257 mRNA Translation: AAH24257.1 BC031294 mRNA Translation: AAH31294.1 BC110321 mRNA Translation: AAI10322.1 |
CCDSi | CCDS484.1 |
PIRi | A56021 |
RefSeqi | NP_001246.2, NM_001255.2 |
Genome annotation databases
Ensembli | ENST00000310955; ENSP00000308450; ENSG00000117399 ENST00000372462; ENSP00000361540; ENSG00000117399 |
GeneIDi | 991 |
KEGGi | hsa:991 |
UCSCi | uc001cix.4, human |
Similar proteinsi
Cross-referencesi
Web resourcesi
Atlas of Genetics and Cytogenetics in Oncology and Haematology |
NIEHS-SNPs |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U05340 mRNA Translation: AAA19017.1 AF099644 mRNA Translation: AAD16405.1 AK312780 mRNA Translation: BAG35643.1 BT007388 mRNA Translation: AAP36052.1 DQ473545 Genomic DNA Translation: ABE96834.1 AL139289 Genomic DNA No translation available. CH471059 Genomic DNA Translation: EAX07101.1 CH471059 Genomic DNA Translation: EAX07102.1 BC000624 mRNA Translation: AAH00624.1 BC001088 mRNA Translation: AAH01088.1 BC006272 mRNA Translation: AAH06272.1 BC009425 mRNA Translation: AAH09425.1 BC009426 mRNA Translation: AAH09426.1 BC010044 mRNA Translation: AAH10044.1 BC012803 mRNA Translation: AAH12803.1 BC012827 mRNA Translation: AAH12827.1 BC013303 mRNA Translation: AAH13303.1 BC015998 mRNA Translation: AAH15998.1 BC024257 mRNA Translation: AAH24257.1 BC031294 mRNA Translation: AAH31294.1 BC110321 mRNA Translation: AAI10322.1 |
CCDSi | CCDS484.1 |
PIRi | A56021 |
RefSeqi | NP_001246.2, NM_001255.2 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
4GGA | X-ray | 2.04 | A | 81-499 | [»] | |
4GGC | X-ray | 1.35 | A | 161-477 | [»] | |
4GGD | X-ray | 2.44 | A/B | 71-499 | [»] | |
4N14 | X-ray | 2.10 | A | 165-477 | [»] | |
5G04 | electron microscopy | 4.00 | R | 1-499 | [»] | |
5KHR | electron microscopy | 6.10 | R | 1-499 | [»] | |
5KHU | electron microscopy | 4.80 | R/S | 1-499 | [»] | |
5LCW | electron microscopy | 4.00 | Q | 126-499 | [»] | |
R | 1-499 | [»] | ||||
6F0X | electron microscopy | 4.60 | Q | 1-499 | [»] | |
6Q6G | electron microscopy | 3.20 | R | 1-499 | [»] | |
6Q6H | electron microscopy | 3.20 | R | 1-499 | [»] | |
SMRi | Q12834 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 107427, 196 interactors |
ComplexPortali | CPX-3946, Mitotic Checkpoint Complex CPX-6087, Anaphase-Promoting complex, CDC20 variant |
CORUMi | Q12834 |
DIPi | DIP-29655N |
ELMi | Q12834 |
IntActi | Q12834, 72 interactors |
MINTi | Q12834 |
STRINGi | 9606.ENSP00000361540 |
Protein family/group databases
TCDBi | 9.A.61.2.2, the domain of unknown function 3339 (duf3339) family |
PTM databases
iPTMneti | Q12834 |
PhosphoSitePlusi | Q12834 |
SwissPalmi | Q12834 |
Genetic variation databases
BioMutai | CDC20 |
DMDMi | 37537762 |
Proteomic databases
EPDi | Q12834 |
jPOSTi | Q12834 |
MassIVEi | Q12834 |
MaxQBi | Q12834 |
PaxDbi | Q12834 |
PeptideAtlasi | Q12834 |
PRIDEi | Q12834 |
ProteomicsDBi | 58976 |
Protocols and materials databases
Antibodypediai | 3864, 682 antibodies |
DNASUi | 991 |
Genome annotation databases
Ensembli | ENST00000310955; ENSP00000308450; ENSG00000117399 ENST00000372462; ENSP00000361540; ENSG00000117399 |
GeneIDi | 991 |
KEGGi | hsa:991 |
UCSCi | uc001cix.4, human |
Organism-specific databases
CTDi | 991 |
DisGeNETi | 991 |
GeneCardsi | CDC20 |
HGNCi | HGNC:1723, CDC20 |
HPAi | ENSG00000117399, Tissue enhanced (lymphoid tissue, testis) |
MIMi | 603618, gene |
neXtProti | NX_Q12834 |
OpenTargetsi | ENSG00000117399 |
PharmGKBi | PA26257 |
VEuPathDBi | HostDB:ENSG00000117399.13 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0305, Eukaryota |
GeneTreei | ENSGT00950000183104 |
HOGENOMi | CLU_014831_6_1_1 |
InParanoidi | Q12834 |
OMAi | WSPHKKE |
OrthoDBi | 1220675at2759 |
PhylomeDBi | Q12834 |
TreeFami | TF101065 |
Enzyme and pathway databases
UniPathwayi | UPA00143 |
PathwayCommonsi | Q12834 |
Reactomei | R-HSA-141405, Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141430, Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-174048, APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174113, SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174154, APC/C:Cdc20 mediated degradation of Securin R-HSA-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-176407, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176408, Regulation of APC/C activators between G1/S and early anaphase R-HSA-176409, APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176417, Phosphorylation of Emi1 R-HSA-179409, APC-Cdc20 mediated degradation of Nek2A R-HSA-2467813, Separation of Sister Chromatids R-HSA-2500257, Resolution of Sister Chromatid Cohesion R-HSA-5663220, RHO GTPases Activate Formins R-HSA-5689880, Ub-specific processing proteases R-HSA-68877, Mitotic Prometaphase R-HSA-9648025, EML4 and NUDC in mitotic spindle formation R-HSA-983168, Antigen processing: Ubiquitination & Proteasome degradation |
SignaLinki | Q12834 |
SIGNORi | Q12834 |
Miscellaneous databases
BioGRID-ORCSi | 991, 768 hits in 886 CRISPR screens |
ChiTaRSi | CDC20, human |
GeneWikii | CDC20 |
GenomeRNAii | 991 |
Pharosi | Q12834, Tbio |
PROi | PR:Q12834 |
RNActi | Q12834, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000117399, Expressed in ventricular zone and 167 other tissues |
Genevisiblei | Q12834, HS |
Family and domain databases
DisProti | DP01118 |
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR024977, Apc4_WD40_dom IPR033010, Cdc20/Fizzy IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
PANTHERi | PTHR19918, PTHR19918, 1 hit |
Pfami | View protein in Pfam PF12894, ANAPC4_WD40, 1 hit PF00400, WD40, 4 hits |
SMARTi | View protein in SMART SM00320, WD40, 7 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 1 hit PS50082, WD_REPEATS_2, 3 hits PS50294, WD_REPEATS_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CDC20_HUMAN | |
Accessioni | Q12834Primary (citable) accession number: Q12834 Secondary accession number(s): B2R6Z6 Q9UQI9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 3, 2003 |
Last sequence update: | October 3, 2003 | |
Last modified: | February 10, 2021 | |
This is version 203 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PATHWAY comments
Index of metabolic and biosynthesis pathways - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families