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Protein

Pheromone-regulated protein PRM7

Gene

PRM7

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
YEAST:G3O-29462-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Pheromone-regulated protein PRM7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PRM7
Ordered Locus Names:YDL039C
ORF Names:D2723, D2726, YDL038C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

Saccharomyces Genome Database

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SGDi
S000002197 PRM7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002627501 – 698Pheromone-regulated protein PRM7Add BLAST698

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q12459

PRoteomics IDEntifications database

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PRIDEi
Q12459

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced by pheromone. Down-regulated by RIM101 and inositol.3 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
32019, 113 interactors

STRING: functional protein association networks

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STRINGi
4932.YDL039C

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q12459

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi6 – 520Ser-richAdd BLAST515
Compositional biasi11 – 372Thr-richAdd BLAST362

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

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OMAi
NIQSEVG

Database of Orthologous Groups

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OrthoDBi
EOG092C3IKZ

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q12459-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYRTRSSDEV TTSTDLTSSS DVATSVDPTT SVISSTSADP TTSADSTTST
60 70 80 90 100
VQTTSAGPSN NIGNSTLANS TTFAVSSTSI DPTSSSDVIT STVQTTSIEP
110 120 130 140 150
TTSLVSSNDI TTSTSLNISV VISTSTDSTS LIESTTTVGP HASSSVAGMY
160 170 180 190 200
RTRSSDEVTT STDPTSSSDV ATSADPTSSS AVTTLVDPTT SVVISTSVDQ
210 220 230 240 250
TSSSDVATSV DPTTSVISST SADPTTSADS TTSTVQTTSV DPTSSVVSSA
260 270 280 290 300
PVDPASSVVS LTSSYPTSSS TVTISANSNG SATLAAQTTS IDPVSSIVSS
310 320 330 340 350
SGATTIISSA SIDPASSVVS STSSEPTSFI VSSTSVYSTR PSGPTTSTDL
360 370 380 390 400
ATFSDTIILR VSTTSTSQDT QTVSSSLTDM VSSTGSADLS VSSIQRSQVD
410 420 430 440 450
PSTFAVSNSP VYPTASTGST STGIPIASES LSLSRQQGIS ATSSSSIVTL
460 470 480 490 500
TPVDSASSSR SSATSIIKPN MPVSSNDSKT QSSVSVVDAF QSTKSSYPSI
510 520 530 540 550
TSADPTTLAS ENGLVGSSSS AHPITLDRTY ASAHASVTDI VSRVTDSTRH
560 570 580 590 600
TTLVTSNINI QSEVGNPNYS GPKDTTITKQ SAFMTSPAST STISNVQSTA
610 620 630 640 650
SVMNHSIEDN ISAAASLESV SGTSTKDYSS QSSAIHYTNS FTTTTTNAFI
660 670 680 690
TSKHSIAAVS TGAITSSASI SLIMEGSANI EAVGKLVWLA AALPLAFI
Length:698
Mass (Da):70,123
Last modified:July 22, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEDF687608FCC5268
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA96450 differs from that shown. Reason: Frameshift at position 567.Curated
The sequence CAA96451 differs from that shown. Reason: Frameshift at position 567.Curated
The sequence CAA98597 differs from that shown. Reason: Frameshift at position 567.Curated
The sequence CAA98598 differs from that shown. Reason: Frameshift at position 567.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
Z71781 Genomic DNA Translation: CAA96450.1 Frameshift.
Z71781 Genomic DNA Translation: CAA96451.1 Frameshift.
Z74087 Genomic DNA Translation: CAA98597.1 Frameshift.
Z74087 Genomic DNA Translation: CAA98598.1 Frameshift.
AY557637 Genomic DNA Translation: AAS55963.1
BK006938 Genomic DNA Translation: DAA11816.1

Protein sequence database of the Protein Information Resource

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PIRi
S67571
S67572

NCBI Reference Sequences

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RefSeqi
NP_010245.2, NM_001180098.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YDL039C_mRNA; YDL039C_mRNA; YDL039C

Database of genes from NCBI RefSeq genomes

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GeneIDi
851522

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
sce:YDL039C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71781 Genomic DNA Translation: CAA96450.1 Frameshift.
Z71781 Genomic DNA Translation: CAA96451.1 Frameshift.
Z74087 Genomic DNA Translation: CAA98597.1 Frameshift.
Z74087 Genomic DNA Translation: CAA98598.1 Frameshift.
AY557637 Genomic DNA Translation: AAS55963.1
BK006938 Genomic DNA Translation: DAA11816.1
PIRiS67571
S67572
RefSeqiNP_010245.2, NM_001180098.1

3D structure databases

ProteinModelPortaliQ12459
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32019, 113 interactors
STRINGi4932.YDL039C

Proteomic databases

PaxDbiQ12459
PRIDEiQ12459

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDL039C_mRNA; YDL039C_mRNA; YDL039C
GeneIDi851522
KEGGisce:YDL039C

Organism-specific databases

SGDiS000002197 PRM7

Phylogenomic databases

OMAiNIQSEVG
OrthoDBiEOG092C3IKZ

Enzyme and pathway databases

BioCyciYEAST:G3O-29462-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q12459

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPRM7_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q12459
Secondary accession number(s): D6VRV6, Q99175
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: July 22, 2008
Last modified: December 5, 2018
This is version 101 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names
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